Adapter protein CRKII signaling is involved in the rat pancreatic acini response to reactive oxygen species

Journal of Cellular Biochemistry

Volumn 97, Issue 2, 2006, Pages 359-367

  Andreolotti, Alberto G ^a   Bragado, María J ^a   Tapia, José A ^a   Jensen, Robert T ^b   García Marin, Luis J ^a  

^a UNIVERSITY OF EXTREMADURA   (Spain)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

CrkII; Pancreatic acini; Phosphorylation; Reactive oxygen species; Signaling

Indexed keywords

ACTIN; ADAPTOR PROTEIN; ANTIBODY; HYDROGEN PEROXIDE; PROTEIN CRKII; PROTEIN TYROSINE KINASE INHIBITOR; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ACINAR CELL; ACUTE HEMORRHAGIC PANCREATITIS; ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CELL DAMAGE; CELL ISOLATION; COMPLEX FORMATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSKELETON; GEL MOBILITY SHIFT ASSAY; HORMONE ACTION; MEDIATOR; NONHUMAN; PANCREATITIS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RAT;

ANIMALIA;

EID: 31544446849     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.20624     Document Type: Article

References (30)

1. Andreolotti AG, Bragado MJ, Tapia JA, Jensen RT, Garcia-Marin LJ. 2003. Cholecystokinin rapidly stimulates CrkII function in vivo in rat pancreatic acini. Formation of CrkII-protein complexes. Eur J Biochem 270:4706-4713.
2. Beitner-Johnson D, LeRoith D. 1995. Insulin-like growth factor-I stimulates tyrosine phosphorylation of endogenous c-Crk. J Biol Chem 270:5187-5190.
3. Blakesley VA, Beitner-Johnson D, Van Brooklyn JR, Rani S, Shen-Orr Z, Stannard BS, Spiegel S, LeRoith D. 1997. Sphingosine 1-phosphate stimulates tyrosine phosphorylation of Crk. J Biol Chem 272:16211-16215.
4. Buday L. 1999. Membrane-targeting of signalling molecules by SH2/SH3 domain-containing adaptor proteins. Biochim Biophys Acta 1422:187-204.
5. Dabrowski A, Grady T, Logsdon CD, Williams JA. 1996. Jun kinases are rapidly activated by cholecystokinin in rat pancreas both in vitro and in vivo. J Biol Chem 271:5686-5690.
6. Dabrowski A, Konturek SJ, Konturek JW, Gabryelewicz A. 1999. Role of oxidative stress in the pathogenesis of caerulein-induced acute pancreatitis. Eur J Pharmacol 377:1-11.
7. Dabrowski A, Boguslowicz C, Dabrowska M, Tribillo I, Gabryelewicz A. 2000. Reactive oxygen species activate mitogen-activated protein kinases in pancreatic acinar cells. Pancreas 21:376-384.
8. Feller SM. 2001. Crk family adaptors-signalling complex formation and biological roles. Oncogene 20:6348-6371.
9. Feller SM, Knudsen B, Hanafusa H. 1994. c-Abl kinase regulates the protein binding activity of c-Crk. EMBO J 13:2341-2351.
10. Ferris HA, Tapia JA, García LJ, Jensen RT. 1999. CCKA receptor activation stimulates p130Cas tyrosine phosphorylation, translocation and association with Crk in rat pancreatic acinar cells. Biochemistry 38:1497-1508.
11. FAK and paxillin by cholecystokinin and other neuropeptides. In: LeRoith D, editor. Advances in molecular and cellular endocrinology. Stamford, USA: JAI Press, pp 117-151.
12. rho. Biochem J 327:461-472.
13. Hashimoto Y, Katayama H, Kiyokawa E, Ota S, Kurata T, Gotoh N, Otsuka N, Shibata M, Matsuda M. 1998. Phosphorylation of CrkII adaptor protein at tyrosine 221 by epidermal growth factor receptor. J Biol Chem 273:17186-17191.
14. Kamata H, Hirata H. 1999. Redox regulation of cellular signalling. Cell Signal 11:1-14.
15. Lander HM. 1997. An essential role for free radicals and derived species in signal transduction. FASEB J 11:118-124.
16. Matsuda M, Tanaka S, Nagata S, Kojima A, Kurata T, Shibuya M. 1992. Two species of human CRK cDNA encode proteins with distinct biological activities. Mol Cell Biol 12:3482-3489.
17. Metz DC, Patto RJ, Morzinski JE, Jr., Jensen RT, Turner RJ, Gardner JD. 1992. Thapsigargin defines the roles of cellular calcium in secretagogue- stimulated enzyme secretion from pancreatic acini. J Biol Chem 267: 20620-20629.
18. Pariente JA, Camello C, Camello PJ, Salido GM. 2001. Release of calcium from mitochondrial and nonmitochondrial intracellular stores in mouse pancreatic acinar cells by hydrogen peroxide. J Membr Biol 179:27-35.
19. Peikin SR, Rottman AJ, Batzri S, Gardner JD. 1978. Kinetics of amylase release by dispersed acini prepared from guinea pig pancreas. Am J Physiol 235:743-749.
20. Rankin S, Hooshmand-Rad R, Claesson-Welsh L, Rozengurt E. 1996. Requirement for phosphatidylinositol 3′-kinase activity in platelet-derived growth factor-stimulated tyrosine phosphorylation of p125 focal adhesion kinase and paxillin. J Biol Chem 271:7829-7834.
21. Ren R, Ye ZS, Baltimore D. 1994. Abl protein-tyrosine kinase selects the Crk adapter as a substrate using SH3-binding sites. Gene Dev 8:783-795.
22. Rosado JA, Salido GM, Garcia LJ. 2000. A role for phosphoinositides in tyrosine phosphorylation of p125 focal adhesion kinase in rat pancreatic acini. Cell Signal 12:173-182.
23. Rosado JA, Gonzalez A, Salido GM, Pariente JA. 2002. Effects of reactive oxygen species on actin filament polymerization and amylase secretion in mouse pancreatic acinar cells. Cell Signal 14:547-556.
24. Salmon ED, McKell M, Hays T. 1984. Rapid rate of tubulin dissociation from microtubules in the mitotic spindle in vivo measured by blocking polymerization with colchicine. J Cell Biol 99:1066-1075.
25. Schafer C, Ross SE, Bragado MJ, Groblewski GE, Ernst SA, Williams JA. 1998. A role for the p38 mitogen-activated protein kinase/Hsp 27 pathway in cholecystokinin-induced changes in the actin cytoskeleton in rat pancreatic acini. J Biol Chem 273:24173-24180.
26. Seo JY, Kim H, Seo JT, Kim KH. 2002. Oxidative stress induced cytokine production in isolated rat pancreatic acinar cells: Effects of small-molecule antioxidants. Pharmacology 64:63-70.
27. Steer ML. 1998. Frank Brooks memorial Lecture: The early intraacinar cell events which occur during acute pancreatitis. Pancreas 17:31-37.
28. Tanaka S, Morishita T, Hashimoto Y, Hattori S, Nakamura S, Shibuya M, Matuoka K, Takenawa T, Kurata T, Nagashima K. 1994. C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and GRB2/ASH proteins. Proc Natl Acad Sci USA 91:3443-3447.
29. Tapia JA, Ferris HA, Jensen RT, Garcia LJ. 1999. Cholecystokinin activates PYK2/CAKbeta by a phospholipase C-dependent mechanism and its association with the mitogen-activated protein kinase signaling pathway in pancreatic acinar cells. J Biol Chem 274: 1261-1271.
30. Williams JA. 2001. Intracellular signaling mechanisms activated by cholecystokinin-regulating synthesis and secretion of digestive enzymes in pancreatic acinar cells. Annu Rev Physiol 63:77-97.