Mechanism of inhibition of porcine leukocyte 12-lipoxygenase by the isoform-specific inhibitor 4-(2-oxapentadeca-4-yne)phenylpropanoic acid

Biochemistry

Volumn 38, Issue 50, 1999, Pages 16529-16538

  Richards, Karen M ^a,b   Moody, John S ^a   Marnett, Lawrence J ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONATE 12 LIPOXYGENASE; ARACHIDONIC ACID; HYDROPEROXIDE; PROPIONIC ACID DERIVATIVE;

ARTICLE; BINDING AFFINITY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME INHIBITION; ENZYME KINETICS; ENZYME MECHANISM; ENZYME SPECIFICITY; ENZYME STRUCTURE; OXIDATION; PRIORITY JOURNAL;

ANIMALS; ARACHIDONATE 12-LIPOXYGENASE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FERRIC COMPOUNDS; FERROUS COMPOUNDS; ISOENZYMES; LEUKOCYTES; LINOLEIC ACIDS; LIPID PEROXIDES; LIPOXYGENASE INHIBITORS; OXIDATION-REDUCTION; PEROXIDASES; PHENYLPROPIONATES; RECOMBINANT PROTEINS; SWINE;

SUIDAE;

EID: 0033554873     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi991336s     Document Type: Article

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