-
1
-
-
0033911567
-
New concepts in regulation and function of the insulin-like growth factors: Implications for understanding normal growth and neoplasia
-
Werner H, LeRoith D. New concepts in regulation and function of the insulin-like growth factors: implications for understanding normal growth and neoplasia. Cell Mol Life Sci 2000; 57: 932-942.
-
(2000)
Cell Mol. Life Sci.
, vol.57
, pp. 932-942
-
-
Werner, H.1
LeRoith, D.2
-
2
-
-
0003469985
-
-
Totowa, NJ: Humana Press
-
Rosenfeld RG, Roberts CT Jr. The IGF System: Molecular Biology, Physiology, and Clinical Applications. Totowa, NJ: Humana Press, 1999.
-
(1999)
The IGF System: Molecular Biology, Physiology, and Clinical Applications
-
-
Rosenfeld, R.G.1
Roberts Jr., C.T.2
-
4
-
-
0003169316
-
Molecular biology of the type 1 IGF receptor
-
Rosenfeld RG, Roberts CT Jr, eds. Totowa, NJ: Humana Press
-
Werner H. Molecular biology of the type 1 IGF receptor. In: Rosenfeld RG, Roberts CT Jr, eds. The IGF System: Molecular Biology, Physiology and Clinical Applications. Totowa, NJ: Humana Press, 1999; 63-88.
-
(1999)
The IGF System: Molecular Biology, Physiology and Clinical Applications
, pp. 63-88
-
-
Werner, H.1
-
5
-
-
0026842293
-
Constitutive expression of insulin-like growth factor I and insulin-like growth factor I receptor abrogates all requirements for exogenous growth factors
-
Pietrzkowski Z, Lammers R, Carpenter G, Soderquist AM, Limardo M, Phillips PD, Ullrich A, Baserga R. Constitutive expression of insulin-like growth factor I and insulin-like growth factor I receptor abrogates all requirements for exogenous growth factors. Cell Growth Diff 1992; 3: 199-205.
-
(1992)
Cell Growth Diff.
, vol.3
, pp. 199-205
-
-
Pietrzkowski, Z.1
Lammers, R.2
Carpenter, G.3
Soderquist, A.M.4
Limardo, M.5
Phillips, P.D.6
Ullrich, A.7
Baserga, R.8
-
6
-
-
0026780214
-
Suramin inhibits the growth of human rhabdomyosarcoma by interrupting the insulin-like growth factor II autocrine growth loop
-
Minniti CP, Maggi M, Helman LJ. Suramin inhibits the growth of human rhabdomyosarcoma by interrupting the insulin-like growth factor II autocrine growth loop. Cancer Res 1992; 52: 1830-1835.
-
(1992)
Cancer Res.
, vol.52
, pp. 1830-1835
-
-
Minniti, C.P.1
Maggi, M.2
Helman, L.J.3
-
7
-
-
0029692479
-
The role of the insulin-like growth factor system in human cancer
-
Werner H, LeRoith D. The role of the insulin-like growth factor system in human cancer. Adv Cancer Res 1996; 68: 183-223.
-
(1996)
Adv. Cancer Res.
, vol.68
, pp. 183-223
-
-
Werner, H.1
LeRoith, D.2
-
8
-
-
0031558028
-
The IGF-I receptor in cell growth, transformation and apoptosis
-
Baserga R, Hongo A, Rubini M, Prisco M, Valentinis B. The IGF-I receptor in cell growth, transformation and apoptosis. Biochim Biophys Acta 1997; 1332: F105-F126.
-
(1997)
Biochim. Biophys. Acta
, vol.1332
-
-
Baserga, R.1
Hongo, A.2
Rubini, M.3
Prisco, M.4
Valentinis, B.5
-
9
-
-
0027537988
-
Up-regulation of insulin-like growth factor-I (IGF-1) receptor gene expression in patients with reduced serum IGF-I levels
-
Eshet R, Werner H, Klinger B, Silbergeld A, Laron Z, LeRoith D, Roberts CT Jr. Up-regulation of insulin-like growth factor-I (IGF-1) receptor gene expression in patients with reduced serum IGF-I levels. J Mol Endocrinol 1993; 10: 115-120.
-
(1993)
J. Mol. Endocrinol.
, vol.10
, pp. 115-120
-
-
Eshet, R.1
Werner, H.2
Klinger, B.3
Silbergeld, A.4
Laron, Z.5
LeRoith, D.6
Roberts Jr., C.T.7
-
10
-
-
0020429850
-
Characterization of the somatomedin-C/insulin-like growth factor I (SM-C/IGF-I) receptor on cultured human fibroblast monolayers: Regulation of receptor concentration by SM-C/IGF-I and insulin
-
Rosenfeld RG, Dollar LA. Characterization of the somatomedin-C/insulin-like growth factor I (SM-C/IGF-I) receptor on cultured human fibroblast monolayers: regulation of receptor concentration by SM-C/IGF-I and insulin. J Clin Endocrinol Metab 1982; 55: 434-440.
-
(1982)
J. Clin. Endocrinol. Metab.
, vol.55
, pp. 434-440
-
-
Rosenfeld, R.G.1
Dollar, L.A.2
-
11
-
-
0028340736
-
Platelet-derived growth factor increases the activity of the promoter of the IGF-I receptor gene
-
Rubini M, Werner H, Gandini E, Roberts CT Jr, LeRoith D, Baserga R. Platelet-derived growth factor increases the activity of the promoter of the IGF-I receptor gene. Exp Cell Res 1994; 211: 374-379.
-
(1994)
Exp. Cell Res.
, vol.211
, pp. 374-379
-
-
Rubini, M.1
Werner, H.2
Gandini, E.3
Roberts Jr., C.T.4
LeRoith, D.5
Baserga, R.6
-
12
-
-
0031051392
-
Differential regulation of IGF-I receptor gene expression by IGF-I and basic fibroblast growth factor
-
Hernandez-Sanchez C, Werner H, Roberts CT Jr, Woo EJ, Hun DW, Rosenthal SM, LeRoith D. Differential regulation of IGF-I receptor gene expression by IGF-I and basic fibroblast growth factor. J Biol Chem 1997; 272: 4663-4670.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 4663-4670
-
-
Hernandez-Sanchez, C.1
Werner, H.2
Roberts Jr., C.T.3
Woo, E.J.4
Hun, D.W.5
Rosenthal, S.M.6
LeRoith, D.7
-
13
-
-
0027333425
-
Tumor necrosis factor, other cytokines and disease
-
Tracey KJ, Cerami A. Tumor necrosis factor, other cytokines and disease. Annu Rev Cell Biol 1993; 9: 317-343.
-
(1993)
Annu. Rev. Cell Biol.
, vol.9
, pp. 317-343
-
-
Tracey, K.J.1
Cerami, A.2
-
14
-
-
0035947225
-
Regulation of insulin-like growth factor-I receptor gene expression by tumor necrosis factor-α and interferon-γ
-
Shalita-Chesner M, Katz J, Shemer J, Werner H. Regulation of insulin-like growth factor-I receptor gene expression by tumor necrosis factor-α and interferon-γ. Mol Cell Endocrinol 2001; 176: 1-12.
-
(2001)
Mol. Cell Endocrinol.
, vol.176
, pp. 1-12
-
-
Shalita-Chesner, M.1
Katz, J.2
Shemer, J.3
Werner, H.4
-
15
-
-
0028234529
-
Jak-Stat pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
-
Darnell JE, Kerr IM, Stark GR. Jak-Stat pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 1994; 264: 1415-1421.
-
(1994)
Science
, vol.264
, pp. 1415-1421
-
-
Darnell, J.E.1
Kerr, I.M.2
Stark, G.R.3
-
16
-
-
0030272581
-
Roles of the JAK-STAT system in signal transduction via cytokine receptors
-
Watanabe S, Arai K. Roles of the JAK-STAT system in signal transduction via cytokine receptors. Curr Opin Gen Dev 1996; 6: 587-596.
-
(1996)
Curr. Opin. Gen. Dev.
, vol.6
, pp. 587-596
-
-
Watanabe, S.1
Arai, K.2
-
18
-
-
0029655971
-
Function of Stat2 protein in transcriptional activation by alpha interferon
-
Qureshi SA, Leung S, Kerr IM, Stark GR, Darnell JE Jr. Function of Stat2 protein in transcriptional activation by alpha interferon. Mol Cell Biol 1996; 16: 288-293.
-
(1996)
Mol. Cell Biol.
, vol.16
, pp. 288-293
-
-
Qureshi, S.A.1
Leung, S.2
Kerr, I.M.3
Stark, G.R.4
Darnell Jr., J.E.5
-
19
-
-
0028937707
-
Spacing of palindromic half sites as a determinant of selective STAT (signal transducers and activators of transcription) DNA binding and transcriptional activity
-
Seidel HM, Milocco LH, Lamb P, Darnell JE Jr, Stein RB, Rosen J. Spacing of palindromic half sites as a determinant of selective STAT (signal transducers and activators of transcription) DNA binding and transcriptional activity. Proc Natl Acad Sci USA 1995; 92: 3041-3045.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 3041-3045
-
-
Seidel, H.M.1
Milocco, L.H.2
Lamb, P.3
Darnell Jr., J.E.4
Stein, R.B.5
Rosen, J.6
-
20
-
-
0030046753
-
STATs: Signal transducers and activators of transcription
-
Ihle JN. STATs: signal transducers and activators of transcription. Cell 1996; 84: 331-334.
-
(1996)
Cell
, vol.84
, pp. 331-334
-
-
Ihle, J.N.1
-
21
-
-
0030840464
-
STATs and gene regulation
-
Darnell JE Jr. STATs and gene regulation. Science 1997; 277: 1630-1635.
-
(1997)
Science
, vol.277
, pp. 1630-1635
-
-
Darnell Jr., J.E.1
-
22
-
-
0029757120
-
Wild type and mutant p53 differentially regulate transcription of the insulin-like growth factor I receptor gene
-
Werner H, Karnieli E, Rauscher FJ III, LeRoith D. Wild type and mutant p53 differentially regulate transcription of the insulin-like growth factor I receptor gene. Proc Natl Acad Sci USA 1996; 93: 8318-8323.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 8318-8323
-
-
Werner, H.1
Karnieli, E.2
Rauscher III, F.J.3
LeRoith, D.4
-
23
-
-
0031769052
-
p53 regulates IGF-I receptor expression and IGF-I induced tyrosine phosphorylation in an osteosarcoma cell line: Interaction between p53 and Sp1
-
Ohlsson C, Kley N, Werner H, LeRoith D. p53 regulates IGF-I receptor expression and IGF-I induced tyrosine phosphorylation in an osteosarcoma cell line: interaction between p53 and Sp1. Endocrinology 1998; 139: 1101-1107.
-
(1998)
Endocrinology
, vol.139
, pp. 1101-1107
-
-
Ohlsson, C.1
Kley, N.2
Werner, H.3
LeRoith, D.4
-
24
-
-
0028318393
-
Transcriptional repression of the insulin-like growth factor I receptor (IGF-I-R) gene by the tumor suppressor WT1 involves binding to sequences both upstream and downstream of the IGF-I-R gene transcription start site
-
Werner H, Rauscher FJ III, Sukhatme VP, Drummond IA, Roberts CT Jr, LeRoith D. Transcriptional repression of the insulin-like growth factor I receptor (IGF-I-R) gene by the tumor suppressor WT1 involves binding to sequences both upstream and downstream of the IGF-I-R gene transcription start site. J Biol Chem 1994; 269: 12577-12582.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 12577-12582
-
-
Werner, H.1
Rauscher III, F.J.2
Sukhatme, V.P.3
Drummond, I.A.4
Roberts Jr., C.T.5
LeRoith, D.6
-
25
-
-
0026801581
-
Structural and functional analysis of the insulin-like growth factor I receptor gene promoter
-
Werner H, Bach MA, Stannard B, Roberts CT Jr, LeRoith D. Structural and functional analysis of the insulin-like growth factor I receptor gene promoter. Mol Endocrinol 1992; 6: 1545-1558.
-
(1992)
Mol. Endocrinol.
, vol.6
, pp. 1545-1558
-
-
Werner, H.1
Bach, M.A.2
Stannard, B.3
Roberts Jr., C.T.4
LeRoith, D.5
-
26
-
-
0027396719
-
Tumor necrosis factor-α and interferon-γ inhibit insulin-like growth factor II gene expression in human fetal adrenal cell cultures
-
Ilvesmaki V, Jaattela M, Saksela E, Voutilainen R. Tumor necrosis factor-α and interferon-γ inhibit insulin-like growth factor II gene expression in human fetal adrenal cell cultures. Mol Cell Endocrinol 1993; 91: 59-65.
-
(1993)
Mol. Cell Endocrinol.
, vol.91
, pp. 59-65
-
-
Ilvesmaki, V.1
Jaattela, M.2
Saksela, E.3
Voutilainen, R.4
-
27
-
-
0028986107
-
Interferon-γ inhibits macrophage insulin-like growth factor-I synthesis at the transcriptional level
-
Arkins S, Rebeiz N, Brunke-Reese DB, Biragyn A, Kelley KW. Interferon-γ inhibits macrophage insulin-like growth factor-I synthesis at the transcriptional level. Mol Endocrinol 1995; 9: 350-360.
-
(1995)
Mol. Endocrinol.
, vol.9
, pp. 350-360
-
-
Arkins, S.1
Rebeiz, N.2
Brunke-Reese, D.B.3
Biragyn, A.4
Kelley, K.W.5
-
28
-
-
0029117521
-
Tumor necrosis factor α, interferon γ and dexamethasone regulate IGF-I-maintained collagen production in cultured human fibroblasts
-
Bird JL, Tyler JA. Tumor necrosis factor α, interferon γ and dexamethasone regulate IGF-I-maintained collagen production in cultured human fibroblasts. J Endocrinol 1995; 147: 167-176.
-
(1995)
J. Endocrinol.
, vol.147
, pp. 167-176
-
-
Bird, J.L.1
Tyler, J.A.2
-
29
-
-
0032853188
-
Tumor necrosis factor α and interferon γ-induced cell growth arrest is mediated via insulin-like growth factor binding protein-3
-
Katz J, Nasatzky E, Werner H, LeRoith D, Shemer J. Tumor necrosis factor α and interferon γ-induced cell growth arrest is mediated via insulin-like growth factor binding protein-3. Growth Horm IGF Res 1999; 9: 174-178.
-
(1999)
Growth Horm. IGF Res.
, vol.9
, pp. 174-178
-
-
Katz, J.1
Nasatzky, E.2
Werner, H.3
LeRoith, D.4
Shemer, J.5
-
30
-
-
0030833570
-
Requirement of STAT5b for sexual dimorphism of body growth rates and liver gene expression
-
Udy GB, Towers RP, Snell RG, Wilkins RJ, Park SH, Ram PA, Waxman DJ, Davey HW. Requirement of STAT5b for sexual dimorphism of body growth rates and liver gene expression. Proc Natl Acad Sci USA 1997; 94: 7239-7244.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 7239-7244
-
-
Udy, G.B.1
Towers, R.P.2
Snell, R.G.3
Wilkins, R.J.4
Park, S.H.5
Ram, P.A.6
Waxman, D.J.7
Davey, H.W.8
-
31
-
-
0034658690
-
Divergent roles of STAT1 and STAT5 in malignancy as revealed by gene disruptions in mice
-
Levy DE, Gilliland DG. Divergent roles of STAT1 and STAT5 in malignancy as revealed by gene disruptions in mice. Oncogene 2000; 19: 2505-2510.
-
(2000)
Oncogene
, vol.19
, pp. 2505-2510
-
-
Levy, D.E.1
Gilliland, D.G.2
-
32
-
-
0033604523
-
The IGF-I receptor in cancer research
-
Baserga R. The IGF-I receptor in cancer research. Exp Cell Res 1999; 253: 1-6.
-
(1999)
Exp. Cell Res.
, vol.253
, pp. 1-6
-
-
Baserga, R.1
-
33
-
-
0029027521
-
The insulin-like growth factor I receptor protects tumor cells from apoptosis in vivo
-
Resnicoff M, Abraham D, Yutanawiboonchai W, Rotman HL, Kajstura J, Rubin R, Zoltick P, Baserga R. The insulin-like growth factor I receptor protects tumor cells from apoptosis in vivo. Cancer Res 1995; 55: 2463-2469.
-
(1995)
Cancer Res.
, vol.55
, pp. 2463-2469
-
-
Resnicoff, M.1
Abraham, D.2
Yutanawiboonchai, W.3
Rotman, H.L.4
Kajstura, J.5
Rubin, R.6
Zoltick, P.7
Baserga, R.8
-
34
-
-
0037061736
-
Stat1 negatively regulates angiogenesis, tumorigenicity and metastasis of tumor cells
-
Huang S, Bucana CD, Van Arsdall M, Fidler IJ. Stat1 negatively regulates angiogenesis, tumorigenicity and metastasis of tumor cells. Oncogene 2002; 21: 2504-2512.
-
(2002)
Oncogene
, vol.21
, pp. 2504-2512
-
-
Huang, S.1
Bucana, C.D.2
Van Arsdall, M.3
Fidler, I.J.4
-
36
-
-
0032516898
-
Transcriptional activation of the p21 (WAF1, CIP1, SDI1) gene by interleukin-6 type cytokines. A prerequisite for their pro-differentiating and anti-apoptotic effects on human osteoblastic cells
-
Bellido T, O'Brien CA, Roberson PK, Manolagas SC. Transcriptional activation of the p21 (WAF1, CIP1, SDI1) gene by interleukin-6 type cytokines. A prerequisite for their pro-differentiating and anti-apoptotic effects on human osteoblastic cells. J Biol Chem 1998; 273: 21137-21144.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 21137-21144
-
-
Bellido, T.1
O'Brien, C.A.2
Roberson, P.K.3
Manolagas, S.C.4
-
37
-
-
0027278677
-
Increased expression of the insulin-like growth factor-I receptor gene, IGFIR, in Wilms' tumor is correlated with modulation of IGFIR promoter activity by the WT1 Wilms' tumor gene product
-
Werner H, Re GG, Drummond IA, Sukhatme VP, Rauscher FJ III, Sens DA, Garvin AJ, LeRoith D, Roberts CT Jr. Increased expression of the insulin-like growth factor-I receptor gene, IGFIR, in Wilms' tumor is correlated with modulation of IGFIR promoter activity by the WT1 Wilms' tumor gene product. Proc Natl Acad Sci USA 1993; 90: 5828-5832.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 5828-5832
-
-
Werner, H.1
Re, G.G.2
Drummond, I.A.3
Sukhatme, V.P.4
Rauscher III, F.J.5
Sens, D.A.6
Garvin, A.J.7
LeRoith, D.8
Roberts Jr., C.T.9
|