Tridimensional activation patterns of acquired torsade-de-pointes-tachycardias in dogs with chronic AV-block

Basic Research in Cardiology

Volumn 99, Issue 4, 2004, Pages 288-298

  Schreiner, Kirsten D ^a   Voss, Frederik ^b   Senges, Julia C ^a   Becker, Ruediger ^a   Kraft, Patrizia ^a   Bauer, Alexander ^a   Kelemen, Kamilla ^a   Kuebler, Wolfgang ^a   Vos, Marc A ^b   Schoels, Wolfgang ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

Acquired long QT syndrome; Electrophysiology; Mapping; Polymorphic ventricular tachycardia

Indexed keywords

ALMOKALANT; ANTHOPLEURIN A; ANTIARRHYTHMIC AGENT; DOFETILIDE; SOTALOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATRIOVENTRICULAR BLOCK; BODY WEIGHT; CONTROLLED STUDY; DOG; DRUG EXPOSURE; ELECTRODE; ENDOCARDIUM; HEART REPOLARIZATION; HEART SIZE; HEART VENTRICLE; HEART VENTRICLE HYPERTROPHY; HEART VENTRICLE TACHYCARDIA; IMAGE RECONSTRUCTION; NONHUMAN; QT INTERVAL; REENTRY TACHYCARDIA; REFRACTORY PERIOD; STATISTICAL ANALYSIS; THREE DIMENSIONAL IMAGING; TORSADE DES POINTES;

EID: 3142725715     PISSN: 03008428     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00395-004-0469-4     Document Type: Article

References (30)

1. Allessie MA, Lammers WJEP, Bonke IM et al. (1984) Intra-atrial reentry as a mechanism for atrial flutter induced by acetylcholine and rapid pacing in the dog. Circulation 70: 123-135
2. Antzelevitch C, Sicouri S, Liu DW et al. (1991) Heterogeneity within the ventricular wall: electrophysiology and pharmacology of epicardial, endocardial, and M cells. Circ Res 69: 1427-1449
3. Anyukhovsky EP, Sosunov EA, Rosen MR et al. (1996) Regional differences in electrophysiological properties of epicardium, midmyocardium, and endocardium: in vitro and in vivo correlations. Circulation 94: 1981-1988
4. Aronson RS (1980) Characteristics of action potentials of hypertrophied myocardium from rats with renal hypertension. Circ Res 47: 443-454
5. Aronson RS, Ming Z (1993) Cellular mechanisms of arrhythmias in hypertrophied and failing myocardium. Circulation 87: V1176-V1183
6. Bauer A, Becker R, Schoels W et al. (1999) Rate- and site dependent effects of propafenone, dofetilide, and the new Iks-blocking agent chromanol 293b on individual muscle layers of the intact canine heart. Circulation 100: 2184-2190
7. Carlsson L, Abrahamsson C, Andersson B et al. (1993) Proarrhythmic effects of the class III agent Almokalant: importance of infusion rate, QT dispersion, and early afterdepolarizations. Cardiovasc Res 27: 2186-2193
8. Duker G, Almgren O, Carlsson L (1992) Electrophysiologic and hemodynamic effects of H 234/09 (Almokalant), Quinidine and (+)-Sotalol in the anesthetized dog. J Cardiovasc Pharmacol 20: 458-465
9. El-Sherif N, Caref EB, Yin H, Restivo M (1996) The electrophysiological mechanism of ventricular arrhythmias in the long QT syndrome. Tridimensional mapping of activation and recovery patterns. Circ Res 79: 474-492
10. Gilmour RF, Riccio ML, Locati EH et al. (1997) Time-and rate-dependent alterations of the QT interval precede the onset of torsade de pointes in patients with acquired QT prolongation. J Am Coll Cardiol 30: 209-217
11. Gough WB, Mehra R, Restivo M et al. (1985) Reentrant ventricular arrhythmia in the late myocardial infarction period in the dog. 13. Circ Res 57: 432
12. Katz AM (1993) Cardiac ion channels. N Engl J Med 17:1244-1252
13. Kowey PR, Friehling TD, Sewter J et al. (1991) Electrophysiological effects of left ventricular hypertrophy: effect of calcium and potassium channel blockade. Circulation 83: 2067-2075
14. Kozhevnikov DO, Yamamoto K, Robotis D, Restivo M, El-Sherif N (2002) Electrophysiological mechanism of enhanced susceptibility of hypertrophied heart to acquired torsade de pointes arrhythmias. Tridimensional mapping of activation and recovery patterns. Circulation 105: 1128-1134
15. Mattioni TA, Zheutlin TA, Sarmiento JJ et al. (1989) Amiodarone in patients with previous drug-mediated torsade de pointes. Ann of Int Med 111: 574-580
16. McNeil DJ, Davies RO, Deitchman D (1993) Clinical safety profile in the treatment of arrhythmias. Am J Cardiol 72: 44A-50A
17. Nayebpour M, Solymoss BC, Nattel S (1989) Cardiovascular and metabolic effects of cesium chloride injection in dogs-limitations as a model for the long QT syndrome. Cardiovasc Res 23: 756-766
18. Schoels W, Gough WB, Restivo M et al. (1991) Circus movement atrial flutter in the canine sterile pericarditis model: activation patterns during entrainment and termination of single-loop reentry in vivo. Circulation 83: 1716-1730
19. Schwartz PJ (1983) The idiopathic long QT syndrome. Ann Intern Med 99: 561-562
20. Senges JC, Sterns LD, Schoels W et al. (2000) Cesium chloride induced ventricular arrhythmias in dogs: three-dimensional activation patterns and their relation to the cesium dose applied. Basic Res Cardiol 95: 152-162
21. Sipido KR, Volders PGA, de Groot SHM et al. (2000) Enhanced Ca2+ release and Na/Ca exchange activity in hypertrophied canine ventricular myocytes: potential link between contractil adaptation and arrhythmogenesis. Circulation 102: 2137-2144
22. Surawicz B (1989) Electrophysiological substrate of Torsade de pointes. Dispersion of repolarisation or early afterdepolarisation. J Am Coll Cardiol 14: 172-182
23. Surawicz B, Knoebel SB (1984) Long QT: good, bad or indifferent? J Am Coll Cardiol 4: 398-413
24. Verduyn SC, Vos MA, van der Zande J et al. (1997) Further observations to elucidate the role of interventricular dispersion of repolarization and early afterdepolarizations in the genesis of acquired torsade de pointes arrhythmias: a comparison between Almokalant and d-sotalol using the dog as ist own control. J Am Coll Cardiol 30:1575-1584
25. Volders PGA, Sipido KR, Vos MA et al. (1998) Cellular basis of biventricular hypertrophy and arrhythmogenesis in dogs with chronic complete atrioventricular block and acquired torsade de pointes. Circulation 98: 1136-1147
26. + currents in dogs with chronic complete atrioventricular block and acquired torsades de pointes. Circulation 100: 2455-2461
27. Vos MA, de Groot SHM, Verduyn SC et al. (1998) Enhanced susceptibility for acquired torsade de pointes arrhythmias in the dog with chronic, complete av block is related to cardiac hypertrophy and electrical remodeling. Circulation 98: 1125-1135
28. Vos MA, Verduyn SC, Gorgels APM et al. (1995) Reproducible induction of early afterdepolarizations and torsade de pointes arrhythmias by d-sotalol and pacing in dogs with chronic atrioventricular block. Circulation 91: 864-872
29. Voss F, Schreiner KD, Schoels W (2002) Refractory patterns and susceptibility to drug-induced polymorphic ventricular tachycardias in dogs with chronic atrioventricular lock: relation to the type of anesthesia. J Cardiovasc Pharmacol 40: 651-659
30. Akar FG, Yan GX, Antzelevitch C, Rosenbaum DS (2002) Unique topographical distribution of M cells underlies reentrant mechanism of torsade de pointes in the long-QT syndrome. Circulation 105: 1247-1253