A genuine clotrimazole γ-cyclodextrin inclusion complex-isolation, antimycotic activity, toxicity and an unusual dissolution rate

International Journal of Pharmaceutics

Volumn 176, Issue 1, 1998, Pages

  Pedersen, Morten ^a   Bjerregaard, Simon ^b   Jacobsen, Jette ^b   Mehlsen Sørensen, Alex ^b  

^a PEDCY   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Antimycotic; Cell culture TR146; Cyclodextrin; Dissolution rate; Erythrocytes; Inclusion complex; Solubility diagram; Supersaturation; Toxicity

Indexed keywords

ALPHA CYCLODEXTRIN; BETA CYCLODEXTRIN; CLOTRIMAZOLE; GAMMA CYCLODEXTRIN;

ANTIFUNGAL ACTIVITY; ARTICLE; CANDIDA ALBICANS; COMPLEX FORMATION; DIFFERENTIAL SCANNING CALORIMETRY; DISSOLUTION; DRUG MIXTURE; DRUG SOLUBILITY; HEMOLYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; PRIORITY JOURNAL; TOXICITY TESTING; X RAY POWDER DIFFRACTION;

EID: 3142724624     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(98)00310-X     Document Type: Article

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