27-Hydroxycholesterol inhibits neutral sphingomyelinase in cultured human endothelial cells

Life Sciences

Volumn 75, Issue 13, 2004, Pages 1567-1577

  Zhou, Qi ^a   Band, Mark R ^b   Hernandez, Alvaro ^b   Liu, Zonglin L ^c   Kummerow, Fred A ^a,b  

^a HE Moore Heart Research Foundation   (United States)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^c NATIONAL CENTER FOR AGRICULTURAL UTILIZATION RESEARCH   (United States)

Author keywords

27 hydroxycholesterol; Cultured human endothelial cells; Neutral sphingomyelinase; Sphingomyelin content

Indexed keywords

26 HYDROXYCHOLESTEROL; CARBON 14; DESIPRAMINE; GLUTATHIONE; MESSENGER RNA; SPHINGOMYELIN; SPHINGOMYELIN PHOSPHODIESTERASE; SPHINGOMYELIN PHOSPHODIESTERASE INHIBITOR;

ARTICLE; CATABOLISM; CELL CULTURE; CELL FREE SYSTEM; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; LIPID STORAGE; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UMBILICAL VEIN;

ANALYSIS OF VARIANCE; CARBON RADIOISOTOPES; CELLS, CULTURED; DESIPRAMINE; DNA PRIMERS; ENDOTHELIAL CELLS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUTATHIONE; HUMANS; HYDROXYCHOLESTEROLS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SPECTROPHOTOMETRY; SPHINGOMYELIN PHOSPHODIESTERASE; SPHINGOMYELINS;

EID: 3142705814     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2004.05.004     Document Type: Article

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