Candidate gene approach in association studies: Would the factor V Leiden mutation have been found by this approach?

European Journal of Human Genetics

Volumn 12, Issue 6, 2004, Pages 478-482

  van Hylckama Vlieg, Astrid ^a   Sandkuijl, Lodewijk A ^a   Rosendaal, Frits R ^a   Bertina, Rogier M ^a   Vos, Hans L ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Association study; Candidate gene; Factor V Leiden; Haplotypes

Indexed keywords

ACTIVATED PROTEIN C; ALANINE; ARGININE; BLOOD CLOTTING FACTOR 5 LEIDEN; GLUTAMINE; GLYCINE;

ARTICLE; CASE CONTROL STUDY; CONTROLLED STUDY; EXON; GENE LOCATION; GENE MUTATION; GENE SEQUENCE; GENE STRUCTURE; GENETIC ASSOCIATION; GENETIC PROCEDURES; GENETIC RISK; GENETIC SCREENING; HAPLOTYPE; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; INTRON; MAJOR CLINICAL STUDY; MISSENSE MUTATION; NUCLEOTIDE SEQUENCE; POPULATION GENETICS; PREDICTION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEGRADATION; SINGLE NUCLEOTIDE POLYMORPHISM; THROMBOPHILIA; VEIN THROMBOSIS;

CASE-CONTROL STUDIES; FACTOR V; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENETICS, POPULATION; HUMANS; MUTATION; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS; THROMBOPHILIA; VENOUS THROMBOSIS;

EID: 3142695572     PISSN: 10184813     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.ejhg.5201183     Document Type: Article

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