Soy protein formulas in children: No hormonal effects in long-term feeding

Journal of Pediatric Endocrinology and Metabolism

Volumn 17, Issue 2, 2004, Pages 191-196

  Giampietro, Paolo Gianni ^a,d   Bruno, Giovanna ^b   Furcolo, Giuseppe ^b   Casati, Alessandra ^a   Brunetti, Ercole ^a   Spadoni, Gian Luigi ^c   Galli, Elena ^a  

^a FATEBENEFRATELLI HOSPITAL   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c UNIVERSITY OF ROME TOR VERGATA   (Italy)

^d NONE   (Italy)

Author keywords

Phyto oestrogens; Soy protein formulas

Indexed keywords

ALKALINE PHOSPHATASE BONE ISOENZYME; BIOLOGICAL MARKER; DAIDZEIN; ESTRADIOL; GENISTEIN; GLYCOSIDE; ISOFLAVONE; OSTEOCALCIN; PARATHYROID HORMONE; PHYTOESTROGEN; SOYBEAN PROTEIN;

ALKALINE PHOSPHATASE BLOOD LEVEL; ARTICLE; ARTIFICIAL FEEDING; ARTIFICIAL MILK; BONE AGE; BONE METABOLISM; CHILD; CHILD CARE; CHILD NUTRITION; CLINICAL ARTICLE; CONTROLLED STUDY; ESTRADIOL BLOOD LEVEL; ESTROGEN ACTIVITY; ESTROGEN BLOOD LEVEL; FEMALE; GYNECOMASTIA; HUMAN; LONG TERM CARE; MALE; PARATHYROID HORMONE BLOOD LEVEL; PHYSICAL EXAMINATION; PRECOCIOUS PUBERTY; PROTEIN BLOOD LEVEL;

EID: 3142695548     PISSN: 0334018X     EISSN: None     Source Type: Journal    
DOI: 10.1515/JPEM.2004.17.2.191     Document Type: Article

References (19)

1. Setchell KDR, Welsh MB. High-performance liquid chromatographic analysis of phytoestrogens in soy protein preparation with ultraviolet, electrochemical and thermospray mass spectrometric detection. J Chromatogr 1987; 386: 315-323.
2. Setchell KDR, Zimmer-Nechemias L, Cai J, Heubi JE. Exposure of infants to phyto-oestrogens from soy-based infant formula. Lancet 1997; 350: 23-27.
3. Setchell KDR, Zimmer-Nechemias L, Cai J, Heubi JE. Isoflavone content of infant formulas and the metabolic fate of these phytoestrogens in early life. Am J Clin Nutr 1998; 68 (Suppl): 1453S-1461S.
4. Quak SH, Tan SP. Use of soy-protein formulas and soyfood for feeding infants and children in Asia. Am J Clin Nutr 1998; 68 (Suppl): 1444S-1446S.
5. Anthony MS, Clarkson TB, Williams JK. Effects of soy isoflavones on atherosclerosis: potential mechanisms. Am J Clin Nutr 1998; 68 (Suppl): 1390S- 1393S.
6. Gardner CD, Newell KA, Cherin R, Haskell WL. Effect of soy protein with or without isoflavones relative to milk protein on plasma lipids in hypercholesterolemic postmenopausal women. Am J Clin Nutr 2001; 73: 667-668.
7. Sirtori CR, Lovati MR. Soy protein and cardiovascular disease. Curr Atheroscler Rep 2001; 3: 47-53.
8. Cruz MLA, Wong WW, Mimouni F, Hachey DL, Setchell KD, Klein PD, Tsang RC. Effects of infant nutrition on cholesterol synthesis rates. Pediatr Res 1994; 35: 135-140.
9. Setchell KD, Cassidy A. Dietary isoflavones: biological effects and relevance to human health. J Nutr 1999; 129: 758S-767S.
10. Anderson KE, Lu LJ, Grady JJ, Koen F, Nagamani M. Decreased ovarian hormones during a soy diet: implications for breast cancer prevention. Cancer Res 2000; 60: 4112-4121.
11. Nakagawa H, Yamamoto D, Kiyozuka Y, Tsuta K, Uemura Y, Hioki K, Tsutsui Y, Tsubura A. Effects of genistein and synergistic action in combination with eicosapentaenoic acid on the growth of breast cancer cell lines. J Cancer Res Clin Oncol 2000; 126: 448-454.
12. Messina M. Soyfoods and soybean phyto-oestrogens (isoflavones) as possible alternatives to hormone replacement therapy (HRT). Eur J Cancer 2000; 36 (Suppl 4): 71S-72S.
13. Uesugi T, Toda T, Tsuji K, Ishida H. Comparative study on reduction of bone loss and lipid metabolism abnormality in ovariectomized rats by soy isoflavones, daidzin, genistin, and glycitin. Biol Pharm Bull 2001; 24: 368-372.
14. De Lorenzo A, Andreoli A, Sorge R, Bonamico M, Bedogni G, Battistini N, Barra PF. Comparison of body weight and body height in Italian children aged 6-12 years with American standards. Minerva Pediatr 1995; 47: 101-106.
15. Hugget AC, Pridmore S, Malnoe A, Haschke F, Offord EA. Phyto-oestrogens in soy-based infant formula. Lancet 1997; 350: 815-816.
16. Liener EL. Implications of antinutritional components in soybean foods. Crit Rev Food Sci Nutr 1994; 34: 31-67.
17. Irvine CH, Shand N, Fitzpatrick MG, Alexander SL. Daily intake and urinary excretion of genistein and daidzein by infants fed soy- or dairy-based infant formulas. Am J Clin Nutr 1998; 68 (Suppl 6): 1462S-1465S.
18. Mendez MA, Anthony MS, Arab L. Soy based formulae and infant growth and development: a review. J Nutr 2002; 132: 2127-2130.
19. Strom BL, Schinnar R, Ziegler EE, Barnhart KT, Sammel MD, Macones GA, Stallings VA, Drulis JM, Nelson SE, Hanson SA. Exposure to soy-based formula in infancy and endocrinological and reproductive outcomes in young adulthood. JAMA 2001; 286: 807-814.