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Volumn 29, Issue 5, 2004, Pages 989-996

Altered neuronal-glial signaling in glutamatergic transmission as a unifying mechanism in chronic pain and mental fatigue

Author keywords

Astroglia; Chronic pain; Concentration capacity; Glutamate; Microglia; Neuron

Indexed keywords

ADENOSINE TRIPHOSPHATE; GLUTAMIC ACID; INTERLEUKIN 1; INTERLEUKIN 6; MINOCYCLINE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; NEUROTRANSMITTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OXYGEN RADICAL; PENTOXIFYLLINE; PROPENTOFYLLINE; PROSTAGLANDIN; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR; XANTHINE DERIVATIVE;

EID: 3142693908     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:NERE.0000021243.86287.43     Document Type: Review
Times cited : (33)

References (60)
  • 1
    • 0036788082 scopus 로고    scopus 로고
    • Beyond neurons: Evidence that immune and glial cells contribute to pathological pain states
    • Watkins, L. R. and Maier, S. F. 2002. Beyond neurons: Evidence that immune and glial cells contribute to pathological pain states. Physiol. Rev. 82:981-1011.
    • (2002) Physiol. Rev. , vol.82 , pp. 981-1011
    • Watkins, L.R.1    Maier, S.F.2
  • 3
    • 0001050064 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor involvement in models of acute and persistent pain: Prospects for the development of novel analgesics
    • Varney, M. A. and Gereau, R. W. 4th 2002. Metabotropic glutamate receptor involvement in models of acute and persistent pain: prospects for the development of novel analgesics. Curr. Drug Target CNS Neurol. Disord. 1:283-296.
    • (2002) Curr. Drug Target CNS Neurol. Disord. , vol.1 , pp. 283-296
    • Varney, M.A.1    Gereau IV, R.W.2
  • 4
    • 0034882399 scopus 로고    scopus 로고
    • Spinal cord glia: New players in pain
    • Watkins, L. R., Milligan, E. D., and Maier, S. F. 2001. Spinal cord glia: new players in pain. Pain 93:201-205.
    • (2001) Pain , vol.93 , pp. 201-205
    • Watkins, L.R.1    Milligan, E.D.2    Maier, S.F.3
  • 5
    • 0036972549 scopus 로고    scopus 로고
    • The role of cytokines in the initiation and maintenance of chronic pain
    • Rutkowski, M. D. and DeLeo, J. A. 2002. The role of cytokines in the initiation and maintenance of chronic pain. Drug News Perspect. 15:626-632.
    • (2002) Drug News Perspect. , vol.15 , pp. 626-632
    • Rutkowski, M.D.1    DeLeo, J.A.2
  • 6
    • 0002595890 scopus 로고    scopus 로고
    • Proinflammatory cytokines and glial cells: Their role in neuropathic pain
    • Watkins, L. (ed.), Birkhauser, Basel
    • DeLeo, J. A. and Colburn, R. W. 1999. Proinflammatory cytokines and glial cells: their role in neuropathic pain. Pages 159-182, in Watkins, L. (ed.), Cytokines and pain. Birkhauser, Basel.
    • (1999) Cytokines and Pain , pp. 159-182
    • DeLeo, J.A.1    Colburn, R.W.2
  • 7
    • 0028027868 scopus 로고
    • The possible role of glia in nociceptive processing and hyperalgesia in the spinal cord of the rat
    • Meller, S. T. Dykstra, C., Grzbycki, D., Murphy, S., and Gebhart, G. F. 1994. The possible role of glia in nociceptive processing and hyperalgesia in the spinal cord of the rat. Neuropharmacology 33:1471-1478.
    • (1994) Neuropharmacology , vol.33 , pp. 1471-1478
    • Meller, S.T.1    Dykstra, C.2    Grzbycki, D.3    Murphy, S.4    Gebhart, G.F.5
  • 8
    • 0025096008 scopus 로고
    • Mechanisms of glial-guided neuronal migration in vitro and in vivo
    • Hatten, M. E. and Mason, C. A. 1990. Mechanisms of glial-guided neuronal migration in vitro and in vivo. Experientia 46:907-916.
    • (1990) Experientia , vol.46 , pp. 907-916
    • Hatten, M.E.1    Mason, C.A.2
  • 10
    • 0024458542 scopus 로고
    • Role of glial cells in regulation of the brain ion microenvironment
    • Walz, W. 1989. Role of glial cells in regulation of the brain ion microenvironment. Progr. Neurobiol. 33:309-333.
    • (1989) Progr. Neurobiol. , vol.33 , pp. 309-333
    • Walz, W.1
  • 13
    • 3543008638 scopus 로고    scopus 로고
    • Astrocytic receptors and second messenger systems
    • Hertz, L. (ed.)
    • Hansson, E. and Rönnbäck, L. 2004. Astrocytic receptors and second messenger systems. Hertz, L. (ed.), in Advances in Molecular and Cell Biology. 31:475-501.
    • (2004) Advances in Molecular and Cell Biology , vol.31 , pp. 475-501
    • Hansson, E.1    Rönnbäck, L.2
  • 14
    • 0030820823 scopus 로고    scopus 로고
    • Intracellular calcium oscillations in astrocytes: A highly plastic, bidirectional form of communication between neurons and astrocytes in situ
    • Pasti, L., Volterra, A., Pozzan, T., and Carmignoto, G. 1997. Intracellular calcium oscillations in astrocytes: a highly plastic, bidirectional form of communication between neurons and astrocytes in situ. J. Neurosci. 17:7817-7830.
    • (1997) J. Neurosci. , vol.17 , pp. 7817-7830
    • Pasti, L.1    Volterra, A.2    Pozzan, T.3    Carmignoto, G.4
  • 15
    • 0032890068 scopus 로고    scopus 로고
    • 5-Hydroxytryptamine and glutamate modulate velocity and extent of intercellular calcium signalling in hippocampal astroglial cells in primary cultures
    • Blomstrand, F., Khatibi, S., Muyderman, H., Hansson, E., Olsson, T., and Rönnbäck, L. 1999. 5-Hydroxytryptamine and glutamate modulate velocity and extent of intercellular calcium signalling in hippocampal astroglial cells in primary cultures. Neuroscience 88:1241-1253.
    • (1999) Neuroscience , vol.88 , pp. 1241-1253
    • Blomstrand, F.1    Khatibi, S.2    Muyderman, H.3    Hansson, E.4    Olsson, T.5    Rönnbäck, L.6
  • 16
    • 0028085213 scopus 로고
    • A model for the propagation of intercellular calcium waves
    • Sneyd, J., Charles, A. C., and Sanderson, M. J. 1994. A model for the propagation of intercellular calcium waves. Am. J. Physiol. 266:C293-C302.
    • (1994) Am. J. Physiol. , vol.266
    • Sneyd, J.1    Charles, A.C.2    Sanderson, M.J.3
  • 19
    • 0035824570 scopus 로고    scopus 로고
    • αr-Adrenergic modulation of metabotropic glutamate receptor-induced calcium oscillations and glutamate release
    • Muyderman, H., Ängehagen, M., Sandberg, M., Björklund, U., Olsson, T., Hansson, E., and Nilsson, M. 2001. αr-Adrenergic modulation of metabotropic glutamate receptor-induced calcium oscillations and glutamate release. J. Biol. Chem. 49:46504-46514.
    • (2001) J. Biol. Chem. , vol.49 , pp. 46504-46514
    • Muyderman, H.1    Ängehagen, M.2    Sandberg, M.3    Björklund, U.4    Olsson, T.5    Hansson, E.6    Nilsson, M.7
  • 20
    • 0030222037 scopus 로고    scopus 로고
    • Microglia: A sensor for pathological events in the CNS
    • Kreutzberg, G. W. 1996. Microglia: a sensor for pathological events in the CNS. Trends Neurosci. 19:312-318.
    • (1996) Trends Neurosci. , vol.19 , pp. 312-318
    • Kreutzberg, G.W.1
  • 22
    • 0037336296 scopus 로고    scopus 로고
    • Glial neuronal signaling in the central nervous system
    • Hansson, E. and Rönnbäck, L. 2003. Glial neuronal signaling in the central nervous system. FASEB J. 17:341-348.
    • (2003) FASEB J. , vol.17 , pp. 341-348
    • Hansson, E.1    Rönnbäck, L.2
  • 23
    • 0030840882 scopus 로고    scopus 로고
    • Evidence for the involvement of spinal cord glia in subcutaneous formalin induced hyperalgesia in the rat
    • Watkins, L. R., Martin, D., Ulrich, P., Tracey, K. J., and Maier, S. F. 1997. Evidence for the involvement of spinal cord glia in subcutaneous formalin induced hyperalgesia in the rat. Pain 71:225-235.
    • (1997) Pain , vol.71 , pp. 225-235
    • Watkins, L.R.1    Martin, D.2    Ulrich, P.3    Tracey, K.J.4    Maier, S.F.5
  • 24
    • 0036073658 scopus 로고    scopus 로고
    • Expression of neuron-associated tumor necrosis factor alpha in the brain is increased during persistent pain
    • Covey, W. C., Ignatowski, T. A., Renauld, A. E., Knight, P. R., Nader, N. D., and Spengler, R. N. 2002. Expression of neuron-associated tumor necrosis factor alpha in the brain is increased during persistent pain. Reg. Anesth. Pain Med. 27:357-366.
    • (2002) Reg. Anesth. Pain Med. , vol.27 , pp. 357-366
    • Covey, W.C.1    Ignatowski, T.A.2    Renauld, A.E.3    Knight, P.R.4    Nader, N.D.5    Spengler, R.N.6
  • 25
    • 0029943301 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha inhibits glutamate uptake by primary human astrocytes. Implications for pathogenesis of HIV-1 dementia
    • Fine, S. M., Angel, R. A., Perry, S. W., Epstein, L. G., Rothstein, J. D., Dewhurst, S., and Gelbard, H. A. 1996. Tumor necrosis factor alpha inhibits glutamate uptake by primary human astrocytes. Implications for pathogenesis of HIV-1 dementia. J. Biol. Chem. 271:15303-15306.
    • (1996) J. Biol. Chem. , vol.271 , pp. 15303-15306
    • Fine, S.M.1    Angel, R.A.2    Perry, S.W.3    Epstein, L.G.4    Rothstein, J.D.5    Dewhurst, S.6    Gelbard, H.A.7
  • 26
    • 0034308136 scopus 로고    scopus 로고
    • Extracellular accumulation of nitric oxide, hydrogen peroxide, and glutamate in astrocytic cultures following glutathione depletion, complex I inhibition, and/or lipopolysaccharide-induced activation
    • McNaught, K. S. and Jenner, P. 2000. Extracellular accumulation of nitric oxide, hydrogen peroxide, and glutamate in astrocytic cultures following glutathione depletion, complex I inhibition, and/or lipopolysaccharide-induced activation. Biochem. Pharmacol. 60:979-988.
    • (2000) Biochem. Pharmacol. , vol.60 , pp. 979-988
    • McNaught, K.S.1    Jenner, P.2
  • 27
    • 0035426434 scopus 로고    scopus 로고
    • Glial activation: A driving force for pathological pain
    • Watkins, L. R., Milligan, E. D., and Maier, S. F. 2001. Glial activation: a driving force for pathological pain. Trends Neurosci. 24:450-455.
    • (2001) Trends Neurosci. , vol.24 , pp. 450-455
    • Watkins, L.R.1    Milligan, E.D.2    Maier, S.F.3
  • 28
    • 0030005401 scopus 로고    scopus 로고
    • Function of metabotropic glutamate receptors in learning and memory
    • Riedel, G. 1996. Function of metabotropic glutamate receptors in learning and memory. Trends Neurosci. 19:219-224.
    • (1996) Trends Neurosci. , vol.19 , pp. 219-224
    • Riedel, G.1
  • 30
    • 0028961665 scopus 로고
    • Astrocytes in glutamate neurotransmission
    • Hansson, E. and Rönnbäck, L. 1995. Astrocytes in glutamate neurotransmission. FASEB J. 9:343-350.
    • (1995) FASEB J. , vol.9 , pp. 343-350
    • Hansson, E.1    Rönnbäck, L.2
  • 31
    • 0035287432 scopus 로고    scopus 로고
    • Glia: Listening and talking to the synapse
    • Haydon, P. G. 2001. Glia: listening and talking to the synapse. Nature Neurosci. Rev. 2:185-193.
    • (2001) Nature Neurosci. Rev. , vol.2 , pp. 185-193
    • Haydon, P.G.1
  • 32
    • 0032862658 scopus 로고    scopus 로고
    • Expression patterns and regulation of glutamate transporters in the developing and adult nervous system
    • Sims, K. D. and Robinson, M. B. 1999. Expression patterns and regulation of glutamate transporters in the developing and adult nervous system. Crit. Rev. Neurobiol. 13:169-197.
    • (1999) Crit. Rev. Neurobiol. , vol.13 , pp. 169-197
    • Sims, K.D.1    Robinson, M.B.2
  • 33
    • 0026335130 scopus 로고
    • New roles for glia
    • Barres, B. A. 1991. New roles for glia. J. Neurosci. 11:3685-3694.
    • (1991) J. Neurosci. , vol.11 , pp. 3685-3694
    • Barres, B.A.1
  • 34
    • 0036159649 scopus 로고    scopus 로고
    • Blocked gap junction coupling increases glutamate-induced neurotoxicity in neuron-astrocyte co-cultures
    • Ozog, M. A., Siushansian, R., and Naus, C. C. 2002. Blocked gap junction coupling increases glutamate-induced neurotoxicity in neuron-astrocyte co-cultures. J. Neuropathol. Exp. 61:132-141.
    • (2002) J. Neuropathol. Exp. , vol.61 , pp. 132-141
    • Ozog, M.A.1    Siushansian, R.2    Naus, C.C.3
  • 36
    • 0025196959 scopus 로고
    • Metabolism and role of glutamate in mammalian brain
    • Erecinska, M., and Silver, I. A. 1990. Metabolism and role of glutamate in mammalian brain. Prog. Neurobiol. 35:245-296.
    • (1990) Prog. Neurobiol. , vol.35 , pp. 245-296
    • Erecinska, M.1    Silver, I.A.2
  • 37
    • 0018670663 scopus 로고
    • Functional interactions between neurons and astrocytes. I. Turnover and metabolism of putative amino acid transmitters
    • Hertz, L. 1979. Functional interactions between neurons and astrocytes. I. Turnover and metabolism of putative amino acid transmitters. Prog. Neurobiol. 13:277-323.
    • (1979) Prog. Neurobiol. , vol.13 , pp. 277-323
    • Hertz, L.1
  • 38
    • 0019347565 scopus 로고
    • Transport and metabolism of glutamate and GABA in neurons and glial cells
    • Schousboe, A. 1981. Transport and metabolism of glutamate and GABA in neurons and glial cells. Int. Rev. Neurobiol. 22:1-45.
    • (1981) Int. Rev. Neurobiol. , vol.22 , pp. 1-45
    • Schousboe, A.1
  • 39
    • 0035001341 scopus 로고    scopus 로고
    • Glutamate uptake
    • Danbolt, N. C. 2001. Glutamate uptake. Prog. Neurobiol. 65:1-105.
    • (2001) Prog. Neurobiol. , vol.65 , pp. 1-105
    • Danbolt, N.C.1
  • 40
    • 0036386818 scopus 로고    scopus 로고
    • Novel approaches to targeting glutamate receptors for the treatment of chronic pain: Review article
    • Chizh, B. A. 2002. Novel approaches to targeting glutamate receptors for the treatment of chronic pain: review article. Amino Acids 23:169-176.
    • (2002) Amino Acids , vol.23 , pp. 169-176
    • Chizh, B.A.1
  • 41
    • 0036391844 scopus 로고    scopus 로고
    • Glutamatergic mechanisms in different disease states: Overview and therapeutical implications - An introduction
    • Tzschentke, T. M. 2002. Glutamatergic mechanisms in different disease states: overview and therapeutical implications - an introduction. Amino Acids 23:147-152.
    • (2002) Amino Acids , vol.23 , pp. 147-152
    • Tzschentke, T.M.1
  • 44
    • 0028085245 scopus 로고
    • Psychosocial outcome 5-8 years after severe traumatic brain lesions and the impact of rehabilitation services
    • Schalén, W., Hansson, L., Nordström, G., and Nordström, C -H. 1994. Psychosocial outcome 5-8 years after severe traumatic brain lesions and the impact of rehabilitation services. Brain Injury 8:49-64.
    • (1994) Brain Injury , vol.8 , pp. 49-64
    • Schalén, W.1    Hansson, L.2    Nordström, G.3    Nordström, C.H.4
  • 47
    • 0027488953 scopus 로고
    • Abnormal stimulus processing in posttraumatic stress disorder
    • McFarlane, A. C., Weber, D. L., and Clark, C. R. 1993. Abnormal stimulus processing in posttraumatic stress disorder. Biol. Psychiatry 34:311-320.
    • (1993) Biol. Psychiatry , vol.34 , pp. 311-320
    • McFarlane, A.C.1    Weber, D.L.2    Clark, C.R.3
  • 48
    • 0027282258 scopus 로고
    • Organic mental disorders as hypothetical pathogenetic processes
    • Lindqvist, G. and Malmgren, H. 1993. Organic mental disorders as hypothetical pathogenetic processes. Acta Psychiatr. Scand. (Suppl) 373:5-17.
    • (1993) Acta Psychiatr. Scand. (Suppl) , vol.373 , pp. 5-17
    • Lindqvist, G.1    Malmgren, H.2
  • 49
    • 0036556421 scopus 로고    scopus 로고
    • Brain plasticity and microglia: Is transsynaptic glial activation in the thalamus after limb denervation linked to cortical plasticity and central sensitisation? J
    • Paris
    • Banati, R. B. 2002. Brain plasticity and microglia: is transsynaptic glial activation in the thalamus after limb denervation linked to cortical plasticity and central sensitisation? J. Physiol. (Paris) 96:289-299.
    • (2002) Physiol. , vol.96 , pp. 289-299
    • Banati, R.B.1
  • 50
    • 0036805791 scopus 로고    scopus 로고
    • Hypothalamic-pituitary-adrenal axis, neuroendocrine factors and stress
    • Tsigos, C. and Chrousos, G. P. 2002. Hypothalamic-pituitary-adrenal axis, neuroendocrine factors and stress. J. Psychosom. Res. 53:865-871.
    • (2002) J. Psychosom. Res. , vol.53 , pp. 865-871
    • Tsigos, C.1    Chrousos, G.P.2
  • 51
    • 0026062606 scopus 로고
    • Glucocorticoids inhibit glucose transport and glutamate uptake in hippocampal astrocytes: Implications for glucocorticoid neurotoxicity
    • Virgin, C. E., Jr., Ha, T. P., Packan, D. R., Tombaugh, G. C., Yang, S. H., Horner, H. C., and Sapolsky, R. M. 1991. Glucocorticoids inhibit glucose transport and glutamate uptake in hippocampal astrocytes: implications for glucocorticoid neurotoxicity. J. Neurochem. 57:1422-1428.
    • (1991) J. Neurochem. , vol.57 , pp. 1422-1428
    • Virgin Jr., C.E.1    Ha, T.P.2    Packan, D.R.3    Tombaugh, G.C.4    Yang, S.H.5    Horner, H.C.6    Sapolsky, R.M.7
  • 52
    • 0024822252 scopus 로고
    • Arachidonic acid induces a prolonged inhibition of glutamate uptake into glial cells
    • Barbour, B., Szatkowski, M., Ingledew, N., and Attwell, D. 1989. Arachidonic acid induces a prolonged inhibition of glutamate uptake into glial cells. Nature 342:918-919.
    • (1989) Nature , vol.342 , pp. 918-919
    • Barbour, B.1    Szatkowski, M.2    Ingledew, N.3    Attwell, D.4
  • 54
    • 0028906351 scopus 로고
    • Acidosis causes failure of astrocyte glutamate uptake during hypoxia
    • Swanson, R. A., Farrell, K., and Simon, R. P. 1995. Acidosis causes failure of astrocyte glutamate uptake during hypoxia. J. Cereb. Blood Flow Metab. 15:417-424.
    • (1995) J. Cereb. Blood Flow Metab. , vol.15 , pp. 417-424
    • Swanson, R.A.1    Farrell, K.2    Simon, R.P.3
  • 55
    • 0029804572 scopus 로고    scopus 로고
    • Cytokine modulation of glial glutamate uptake: A possible involvement of nitric oxide
    • Ye, Z. C. and Sontheimer, H. 1996. Cytokine modulation of glial glutamate uptake: a possible involvement of nitric oxide. Neuroreport 7:2181-2185.
    • (1996) Neuroreport , vol.7 , pp. 2181-2185
    • Ye, Z.C.1    Sontheimer, H.2
  • 57
    • 0037312860 scopus 로고    scopus 로고
    • Novel glucocorticoid effects on acute inflammation in the CNS
    • Dinkel, K., MacPherson, A., and Sapolsky, R. M. 2003. Novel glucocorticoid effects on acute inflammation in the CNS. J. Neurochem. 84:705-716.
    • (2003) J. Neurochem. , vol.84 , pp. 705-716
    • Dinkel, K.1    MacPherson, A.2    Sapolsky, R.M.3
  • 58
    • 0033612963 scopus 로고    scopus 로고
    • IL-1β differentially regulates calcium wave propagation between primary human fetal astrocytes via pathways involving P2 receptors and gap junction channels
    • John, G. R., Scemes, E., Suadicani, S. O., Liu, J. S. H., Charles, P. C., Lee, S. C., Spray, D. C., and Brosnan, C. F. 1999. IL-1β differentially regulates calcium wave propagation between primary human fetal astrocytes via pathways involving P2 receptors and gap junction channels. Proc. Natl. Acad. Sci. USA 96:11613-11618.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 11613-11618
    • John, G.R.1    Scemes, E.2    Suadicani, S.O.3    Liu, J.S.H.4    Charles, P.C.5    Lee, S.C.6    Spray, D.C.7    Brosnan, C.F.8
  • 59
    • 0035018058 scopus 로고    scopus 로고
    • Propentofylline, a glial modulating agent exhibits anti-allodynic properties in a rat model of neuropathic pain
    • Sweitzer, S. M., Schubert, P., and DeLeo, J. A. 2001. Propentofylline, a glial modulating agent exhibits anti-allodynic properties in a rat model of neuropathic pain. J. Pharmacol. Exp. Ther. 297:1210-1217.
    • (2001) J. Pharmacol. Exp. Ther. , vol.297 , pp. 1210-1217
    • Sweitzer, S.M.1    Schubert, P.2    DeLeo, J.A.3


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