First-degree heart block in the fetus of an anti-SSA/Ro-positive mother: Reversal after a short course of dexamethasone treatment

Arthritis and Rheumatism

Volumn 50, Issue 7, 2004, Pages 2223-2226

  Vesel, Samo ^a   Mazić, Uroš ^a   Blejec, Tanja ^a   Podnar, Tomaž ^a  

^a UNIVERSITY MEDICAL CENTRE LJUBLJANA   (Slovenia)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; DEXAMETHASONE; LA ANTIBODY; LA ANTIGEN; RO ANTIBODY; UNCLASSIFIED DRUG;

ADULT; ARTICLE; AUTOIMMUNE DISEASE; CASE REPORT; CONGENITAL HEART BLOCK; DOPPLER ECHOGRAPHY; DRUG EFFICACY; EARLY DIAGNOSIS; ECHOCARDIOGRAPHY; FEMALE; FETUS; FETUS DISEASE; FETUS ECHOGRAPHY; FIRST DEGREE HEART BLOCK; HUMAN; MALE; MATERNAL DISEASE; OLIGOHYDRAMNIOS; PR INTERVAL; PRIORITY JOURNAL; SINGLE DRUG DOSE; STEROID THERAPY;

ADULT; ANTIBODIES, ANTINUCLEAR; DEXAMETHASONE; ECHOCARDIOGRAPHY, DOPPLER, PULSED; FEMALE; FETAL HEART; GLUCOCORTICOIDS; HEART BLOCK; HUMANS; PREGNANCY; TREATMENT OUTCOME; ULTRASONOGRAPHY, PRENATAL;

EID: 3142672780     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.20341     Document Type: Article

References (17)

1. Michaelsson M, Engle MA. Congenital complete heart block: an international study of the natural history. Cardiovasc Clin 1972;4:85-101.
2. Tseng CE, Buyon JP. Neonatal lupus syndromes. Rheum Dis Clin North Am 1997;23:31-54.
3. Friedman DM, Rupel A, Glickstein J, Buyon JP. Congenital heart block in neonatal lupus: the pediatric cardiologist's perspective. Indian J Pediatr 2002;69:517-22.
4. Julkunen H, Kaaja R, Siren MK, Mack C, McCready S, Maddison P, et al. Immune-mediated congenital heart block (CHB): identifying and counseling patients at risk for having children with CHB. Semin Arthritis Rheum 1998;28:97-106.
5. Brucato A, Frassi M, Franceschini F, Cimaz R, Faden D, Pisoni MP, et al. Risk of congenital complete heart block in newborns of mothers with anti-Ro/SSA antibodies detected by counterimmunoelectrophoresis: a prospective study of 100 women. Arthritis Rheum 2001;44:1832-5.
6. Buyon JP, Hiebert R, Copel J, Craft J, Friedman D, Skvorvon ML, et al. Autoimmune-associated congenital heart block: demographics, mortality, morbidity and recurrence rates obtained from a national neonatal lupus registry. J Am Coll Cardiol 1998;31:1658-66.
7. Julkunen H, Eronen M. The rate of recurrence of isolated congenital heart block: a population-based study. Arthritis Rheum 2001;44:487-8.
8. Moak JP, Barron KS, Hougen TJ, Wiles HB, Balaji S, Buyon JP, et al. Congenital heart block: development of late-onset cardiomyopathy, a previously underappreciated sequela. J Am Coll Cardiol 2001;37:238-42.
9. Saleeb S, Copel J, Friedman D, Buyon JP. Comparison of treatment with fluorinated glucocorticoids to the natural history of autoantibody-associated congenital heart block: retrospective review of the Research Registry for Neonatal Lupus. Arthritis Rheum 1999;42:2335-45.
10. Rosenthal D, Druzin M, Clifford C, Dubin A. A new therapeutic approach to the fetus with congenital heart block: preemptive, targeted therapy with dexamethasone. Obstet Gynecol 1998;92:689-91.
11. Theander E, Brucato A, Gudmundsson S, Salomonsson S, Wahren-Herlenius M, Manthorpe R. Primary Sjögren's syndrome-treatment of fetal incomplete atrioventricular block with dexamethasone. J Rheumatol 2001;28:373-6.
12. Askanase AD, Friedman DM, Copel J, Dische MR, Dubin A, Buyon JP, et al. Spectrum and progression of conduction abnormalities in infants born to mothers with anti-SSA/Ro-SSB/La antibodies. Lupus 2002;11:145-51.
13. Scott JR. Risk to the children born to the mothers with autoimmune disease. Lupus 2002;11:655-60.
14. Costedaout-Chalumeau N, Amoura Z, Le Thi Hong D, Wechsler B, Vauthier D, Piette JC. Questions about dexamethasone use for the prevention of anti-SSA related congenital heart block. Ann Rheum Dis 2003;62:1010-2.
15. Glickstein JS, Buyon J, Friedman D. Pulsed Doppler echocardiographic assessment of the fetal PR interval. Am J Cardiol 2000;86:236-9.
16. Rosenthal D, Friedman DM, Buyon J, Dubin A. Validation of the Doppler PR interval in the fetus. J Am Soc Echocardiogr 2002;15:1029-30.
17. Buyon JP, Friedman DM. Autoantibody-associated congenital heart block: the clinical perspective. Curr Rheumatol Rep 2003;5:374-8.