MCMV induces neointima in IFN-γR-/- mice: Intimal cell apoptosis and persistent proliferation of myofibroblasts

BMC Musculoskeletal Disorders

Volumn 2, Issue , 2001, Pages 1-12

  Hamamdzic, Damir ^a   Harley, Russell A ^a   Hazen Martin, Debra ^a   LeRoy, E Carwile ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON RECEPTOR; PLATELET DERIVED GROWTH FACTOR A; PLATELET DERIVED GROWTH FACTOR B; TRANSFORMING GROWTH FACTOR BETA1;

ABDOMINAL AORTA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTERITIS; ARTERY INTIMA PROLIFERATION; ARTICLE; CELL INFILTRATION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOMEGALOVIRUS INFECTION; HISTOPATHOLOGY; IMMUNOCOMPETENCE; IMMUNOHISTOCHEMISTRY; IMMUNOSUPPRESSIVE TREATMENT; INCUBATION TIME; INTIMA; ISOLATED ARTERY; ISOLATED HEART; MOUSE; MYOFIBROBLAST; NONHUMAN; UPREGULATION; WHOLE BODY RADIATION;

EID: 3142581897     PISSN: 14712474     EISSN: 14712474     Source Type: Journal    
DOI: 10.1186/1471-2474-2-3     Document Type: Article

References (45)

1. Bouchard C: Physical inactivity. Can J Cardiol 1999, 15 Suppl G:89G-92G
2. Paradis G, Fodor JG: Diet and the prevention of cardiovascular diseases. Can J Cardiol 1999, 15 Suppl G:81G-88G
3. Reeder B, Bouchard C: Obesity and cardiovascular diseases. Can J Cardiol 1999, 15 Suppl G:69G-72G
4. Pickering T: Cardiovascular pathways: socioeconomic status and stress effects on hypertension and cardiovascular function. Ann N Y Acad Sci 1999, 896:262-277
5. Fuster V: Human lesion studies. Ann N Y Acad Sci 1997, 811:207-24
6. Moder KG, Miller TD, Tazelaar HD: Cardiac involvement in systemic lupus erythematosus. Mayo Clin Proc 1999, 74:275-284
7. Cook NS, Zerwes HG, Rudin M, Beckmann N, Schuurman HJ: Chronic graft loss: dealing with the vascular alterations in solid organ transplantation. Transplant Proc 1998, 30(5):2413-2418
8. Kahaleh MB, LeRoy EC: Autimmunity and vascular involvement in systemic sclerosis (SSc). Autoimmunity 1999, 31:195-214
9. Yamashita K, Ouchi K, Shirai M, Gondo T, Nakazawa T, Ito H: Distribution of Chlamydia pneumoniae infection in the atherosclerotic carotid artery. Stroke 1998, 29(4):773-778
10. Muhlestein JB: Bacterial infections and atherosclerosis J Investig Med 1998, 46(8):396-402
11. Pandey JP, LeRoy EC: Human cytomegalovirus and the vasculopathies of autoimmune diseases (especially scleroderma), allograft rejection, and coronary restenosis. Arthritis Rheum 1998, 41:10-15
12. Neidhart M, Kuchen S, Distler O, Bruhlman P, Michel BA, Gay RE, Gay S: Increased serum levels of antibodies against human cytomegalovirus and prevalence of autoantibodies in systemic sclerosis. Arthritis Rheum 1999, 42:389-392
13. Mocarski ES: Cytomegalo viruses and their Replication. Fields Virology. Edited by Fields BN et al. Pennsylvania, Lippincott-Raven, 19962447-2491
14. Nieto FJ, Adam E, Sorlie P, Farzadegan H, Melnick JL, Constock GW, Szklo M: Cohort study of Cytomegalovirus infection as a risk factor for carotid intimal-medial thickening, a measure of subclinical atherosclerosis. Circulation 1996, 94:922-927
15. Lunardi C, Bason C, Navone R, Millo E, Damonte G, Corrocher R, Puccetti A: Systemic sclerosis immunoglobulin G antibodies bind the human cytomegalovims late protein UL94 and induce apoptosis in human endothelial cells. Nat Med 2000, 6(10):1183-1186
16. Kahaleh MB, Fan PS, Otsuka T: Gammadelta receptor bearing T cells in scleroderma: enhanced interaction with vascular endothelial cells in vitro. Clin Immunol 1999, 1(2):188-195
17. Shoenfeld Y, Sherer Y, Harats D: Atherosclerosis as an infectious, inflammatory and autoimmune disease. Trends Immunol 2001, 22(6):293-295
18. Presti RM, Pollock JL, Dal Canto AJ, O'Guin AK, Virgin IV HW: Interferon γ regulates acute and latent murine cytomegalovirus infection and chronic disease of the great vessels. J Exp Med 1998, 188:577-588
19. Sorlie PD, Adam E, Melnick SL, Folsom A, Skelton T, Chambless LE, Barnes R, Melnick JL: Cytomegalovirus/herpesvirus and carotid atherosclerosis: the ARIC study. J Med Virol 1994, 42:33-37
20. Melnick JL, Adam E, DeBakey ME: Cytomegalovirus and atherosclerosis. Bioessays 1995, 17:899-903
21. Koskinen P, Lemstrom K, Bruggeman C, Lautenschlager I, Hayry P: Acute cytomegalovirus infection induces subendothelial inflammation (endothelialitis) in the allograft vascular wall. A possible linkage with enhanced allograft atherosclerosis. Am J Pathol 1994, 144:41-50
22. Dummer S, Lee A, Breinig MK, Kormos Ho RM, Griffth B: Investigation of cytomegalovirus infection as a risk factor for coronary atherosclerosis in the explanted hearts of patients undergoing heart transplantation. J Med Virol 1994, 44:305-309
23. McDonald K, Rector TS, Braunlin EA, Kubo SH, Olivari NT: Association of coronary artery disease in cardiac transplant recipients with cytomegalovirus infection. Am J Cardiol 1989, 64:359-362
24. Grattan MT, Moreno-Cabral CE, Stames VA, Oyer PE, Stinson EB, Shumway NE: Cytomegalovirus infection is associated with cardiac allograft rejection and atherosclerosis. JAMA 1989, 261:3561-3566
25. Speir E, Modali R, Huang ES, Leon MB, Shawl F, Finkel T, Epstein SE: Potential role of human cytomegalovirus and p53 interaction in coronary restenosis. Science 1994, 265:391-394
26. Zhou YF, Leon MB, Waclawiw MA, Popma JJ, Yu ZX, Finkel T, Epstein SE: Association between prior cytomegalovirus infection and the risk of restenosis after coronary atherectomy. N Engl J Med 1996, 335:624-630
27. Yonemicu Y, Nakagawa K, Tanaka S, Mori R, Sugimachi K, Sueishi K: In situ detection of frequent and active infection of human cytomegalovirus in inflammatory abdominal aortic aneurysms: possible pathogenic role in sustained chronic inflammatory reaction. Lab Invest 1996, 74:723-736
28. Tanaka S, Komori K, Okadome K, Sugimachi K, Mori R: Detection of active cytomegalovirus infection in inflammatory aortic aneurysms with RNA polymerase chain reaction. J Vasc Surg 1994, 20:235-243
29. Hafner J, Schneider E, Burg G, Cassina PC: Management of leg ulcers in patients with rheumatoid arthritis or systemic sclerosis: the importance of concomitant arterial and venous disease. J Vasc Surg. 2000, 32(2):322-329
30. Ho M, Veale D, Eastmond C, Nuki G, Belch J: Macrovascular disease and systemic sclerosis. Ann Rheum Dis. 2000, 59(1):39-43
31. Stafford L, Englert H, Gover J, Bertouch J: Distribution of macro vascular disease in scleroderma. Ann Rheum Dis 1998, 57(8):476-479
32. Pollock JL, Virgin HW: Latency, without persistence, of murine cytomegalovirus in spleen and kidney. J Virol 1995, 69:1762-1768
33. Kurz S, Steffens HP, Mayer A, Harris JR, Reddehase MJ: Latency versus persistence of intermittent recurrences: evidence for latent state of murine cytomegalovirus in the lungs. J Virol 1997, 71:2980-2987
34. Mayo D, Armstrong JA, Ho M: Activation of latent murine cytomegalovirus infection: cocultivation, cell transfer, and the effect of immunosuppression. J Infect Dis 1978, 138:890-896
35. Balthesen M, Messerle M, Reddehase MJ: Lungs are a major organ site of cytomegalovirus latency and recurrence. J Virol 1993, 67:5360-5366
36. Dangler CA, Baker SE, Kariuki Njenga M, Chia SH: Murine cytomegalovirus associated arteritis. Vet Pathol 1995, 32:127-133
37. Dechanet J, Merville P, Lim A, Retiere C, Pitard V, Lafarge X, Michelson S, Meric C, Hallet MM, Kourilsky P, Potaux L, Bonneville M, Moreau JF: Implication of gammadelta T cells in the human immune response to cytomegalovirus. J Clin Invest 1999, 103(10):1437-1449
38. Hautmann MB, Madsen CS, Owens GK: A transforming growth factor beta (TGFbeta) control element drives TGFbeta-induced stimulation of smooth muscle alpha-actin gene expression in concert with two CArG elements. J Biol Chem 1997, 272(16):10948-56
39. Funayama H, Ikeda U, Takahashi M, Sakata Y, Kitagawa S, Takahashi Y, Masuyama J, Furukawa Y, Miura Y, Kano S, Matsuda M, Shimada K: Human monocyte-endothelial cell interaction induces platelet-derived growth factor expression. Cardiovasc Res 1998, 37(1):216-224
40. Michelson S, Alcami J, Kim SJ, Danielpour D, Bachelerie F, Picard L, Bessia C, Paya C, Virelizier JL: Human cytomegalovirus infection induces transcription and secretion of transforming growth factor beta 1. J Virol 1994, 68(9):5730-5737
41. Taichman RS, Nassiri MR, Reilly MJ, Ptak RG, Emerson SG, Drach JC: Infection and replication of human cytomegalovirus in bone marrow stromal cells: effects on the production of IL-6, MIP-1alpha, and TGF-beta1. Bone Marrow Transplant 1997, 19(5):471-480
42. Van Coillie E, Van Damme J, Opdenakker G: The MCP/eotaxin subfamily of CC chemokines. Cytokine Growth Factor Rev 1999, 10:61-86
43. Hasegawa M, Sato S, Takehara K: Augmented production of chemokines (monocyte chemotactic protein-1 (MCP-1), macrophage inflammatory protein-1 alpha (MIP-1alpha) and MIP-1beta) in patients with systemic sclerosis: MCP-1 and MIP-1alpha may be involved in the development of pulmonary fibrosis. Clin Exp Immunol 1999, 117(1):159-165
44. Yoshida H, Sumichika H, Hamano S, He X, Minamishima Y, Kimura G, Nomoto K: Induction of apoptosis of T cells by infecting mice with murine cytomegalo virus. J. Virol. 1995, 69:4769-4775
45. Sgonc R, Gruschwitz MS, Dietrich H, Recheis H, Gershwin ME, Wick G: Endothelial cell apoptosis is a primary pathogenic event underlying skin lesions in avian and human scleroderma. J Clin Invest 1996, 98:785-792