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Volumn 5, Issue 6, 2004, Pages 1359-1372

Long-term oral carvedilol in chronic heart failure

Author keywords

blocker therapy; Carvedilol; Chronic heart failure; Sympathetic nervous system

Indexed keywords

AMIODARONE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BISOPROLOL; CAPTOPRIL; CARVEDILOL; CYCLOSPORIN; DIGOXIN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENALAPRIL; ENOXIMONE; FLUOXETINE; HYDROCHLOROTHIAZIDE; METOPROLOL SUCCINATE; METOPROLOL TARTRATE; NEBIVOLOL; RIFAMPICIN; WARFARIN;

EID: 3142528609     PISSN: 14656566     EISSN: None     Source Type: Journal    
DOI: 10.1517/14656566.5.6.1359     Document Type: Review
Times cited : (5)

References (108)
  • 1
    • 0031030370 scopus 로고    scopus 로고
    • The epidemiology of heart failure
    • COWIE MR, MOSTERD A, WOOD DA et al.: The epidemiology of heart failure. Eur. Heart J. (1997) 18(2):208-225.
    • (1997) Eur. Heart J. , vol.18 , Issue.2 , pp. 208-225
    • Cowie, M.R.1    Mosterd, A.2    Wood, D.A.3
  • 2
    • 0026695294 scopus 로고
    • The neurohormonal hypothesis: A theory to explain the mechanism of disease progression in heart failure
    • PACKER M: The neurohormonal hypothesis: a theory to explain the mechanism of disease progression in heart failure. J. Am. Coll. Cardiol. (1992) 20(1):248-254.
    • (1992) J. Am. Coll. Cardiol. , vol.20 , Issue.1 , pp. 248-254
    • Packer, M.1
  • 4
    • 0030663953 scopus 로고    scopus 로고
    • Molecular and cellular mechanisms of myocardial failure
    • COLUCCI WS: Molecular and cellular mechanisms of myocardial failure. Am. J. Cardiol. (1997) 80(11A):15L-25L.
    • (1997) Am. J. Cardiol. , vol.80 , Issue.11 A
    • Colucci, W.S.1
  • 5
    • 0029037793 scopus 로고
    • Structural basis for heart failure. Ventricular remodeling and its pharmacological inhibition
    • COHN JN: Structural basis for heart failure. Ventricular remodeling and its pharmacological inhibition. Circulation (1995) 91(10):2504-2507.
    • (1995) Circulation , vol.91 , Issue.10 , pp. 2504-2507
    • Cohn, J.N.1
  • 6
    • 0024989562 scopus 로고
    • Role of the sympathetic nervous system in the genesis of ventricular arrhythmia
    • PODRID PJ, FUCHS T, CANDINAS R: Role of the sympathetic nervous system in the genesis of ventricular arrhythmia. Circulation (1990) 82(Suppl. I):I103-I113.
    • (1990) Circulation , vol.82 , Issue.SUPPL. I
    • Podrid, P.J.1    Fuchs, T.2    Candinas, R.3
  • 7
    • 0030660245 scopus 로고    scopus 로고
    • Mechanism of action of beta-blocking agents in heart failure
    • BRISTOW MR: Mechanism of action of beta-blocking agents in heart failure. Am. J. Cardiol. (1997) 80(11A):26L-40L.
    • (1997) Am. J. Cardiol. , vol.80 , Issue.11 A
    • Bristow, M.R.1
  • 8
    • 0028271342 scopus 로고
    • Clinical pharmacokinetics and pharmacodynamics of carvedilol
    • MORGAN T: Clinical pharmacokinetics and pharmacodynamics of carvedilol. Clin. Pharmacokinet. (1994) 26(5):335-346.
    • (1994) Clin. Pharmacokinet. , vol.26 , Issue.5 , pp. 335-346
    • Morgan, T.1
  • 9
    • 0023571649 scopus 로고
    • Pharmacokinetics and bioavailability of carvedilol, a vasodilating beta-blocker
    • VON MOLLENDORFF E, REIFF K, NEUGEBAUER G: Pharmacokinetics and bioavailability of carvedilol, a vasodilating beta-blocker. Eur. J. Clin. Pharmacol. (1987) 33(5):511-513.
    • (1987) Eur. J. Clin. Pharmacol. , vol.33 , Issue.5 , pp. 511-513
    • Von Mollendorff, E.1    Reiff, K.2    Neugebauer, G.3
  • 10
    • 0025300364 scopus 로고
    • Stereoselective disposition of carvedilol in man after intravenous and oral administration of the racemic compound
    • NEUGEBAUER G, AKPAN W, KAUFMANN B, REIFF K: Stereoselective disposition of carvedilol in man after intravenous and oral administration of the racemic compound. Eur. J. Clin. Pharmacol. (1990) 38(2):108-111.
    • (1990) Eur. J. Clin. Pharmacol. , vol.38 , Issue.2 , pp. 108-111
    • Neugebauer, G.1    Akpan, W.2    Kaufmann, B.3    Reiff, K.4
  • 12
    • 0030848298 scopus 로고    scopus 로고
    • In vitro identification of the human cytochrome P450 enzymes involved in the metabolism of R(+)- and S(-)-carvedilol
    • OLDHAM HG, CLARKE SE: In vitro identification of the human cytochrome P450 enzymes involved in the metabolism of R(+)- and S(-)-carvedilol. Drug Metab. Dispos. (1997) 25(8):970-977.
    • (1997) Drug Metab. Dispos. , vol.25 , Issue.8 , pp. 970-977
    • Oldham, H.G.1    Clarke, S.E.2
  • 14
    • 0029048320 scopus 로고
    • Carvedilol, a novel multiple action antihypertensive agent with antioxidant activity and the potential for myocardial and vascular protection
    • FEUERSTEIN GZ, RUFFOLO RR Jr: Carvedilol, a novel multiple action antihypertensive agent with antioxidant activity and the potential for myocardial and vascular protection. Eur. Heart J. (1995) 16(Suppl. 11):38-42.
    • (1995) Eur. Heart J. , vol.16 , Issue.SUPPL. 11 , pp. 38-42
    • Feuerstein, G.Z.1    Ruffolo Jr., R.R.2
  • 15
    • 0032506784 scopus 로고    scopus 로고
    • Carvedilol
    • FRISHMAN WH: Carvedilol. N. Engl. J. Med. (1998) 339(24):1759-1765.
    • (1998) N. Engl. J. Med. , vol.339 , Issue.24 , pp. 1759-1765
    • Frishman, W.H.1
  • 16
    • 0025613596 scopus 로고
    • Pharmacokinetics of carvedilol in older and younger patients
    • MORGAN T, ANDERSON A, CRIPPS J, ADAM W: Pharmacokinetics of carvedilol in older and younger patients. J. Hum. Hypertens. (1990) 4(6):709-715.
    • (1990) J. Hum. Hypertens. , vol.4 , Issue.6 , pp. 709-715
    • Morgan, T.1    Anderson, A.2    Cripps, J.3    Adam, W.4
  • 17
    • 0029035966 scopus 로고
    • Stereoselective disposition of carvedilol is determined by CYP2D6
    • ZHOU HH, WOOD AJ: Stereoselective disposition of carvedilol is determined by CYP2D6. Clin. Pharmacol. Ther. (1995) 57(5):518-524.
    • (1995) Clin. Pharmacol. Ther. , vol.57 , Issue.5 , pp. 518-524
    • Zhou, H.H.1    Wood, A.J.2
  • 18
    • 0001088546 scopus 로고    scopus 로고
    • Dose-proportional stereoselective kinetics of carvedilol in patients with CHF
    • TENERO D, ILSON B, BOYLE D et al.: Dose-proportional stereoselective kinetics of carvedilol in patients with CHF. Clin. Pharmacol. Ther. (1996) 59(2):201.
    • (1996) Clin. Pharmacol. Ther. , vol.59 , Issue.2 , pp. 201
    • Tenero, D.1    Ilson, B.2    Boyle, D.3
  • 19
    • 0032957957 scopus 로고    scopus 로고
    • The pharmacokinetics of carvedilol and its metabolites after single and multiple dose oral administration in patients with hypertension and renal insufficiency
    • GEHR TW, TENERO DM, BOYLE DA, QIAN Y, SICA DA, SHUSTERMAN NH: The pharmacokinetics of carvedilol and its metabolites after single and multiple dose oral administration in patients with hypertension and renal insufficiency. Eur. J. Clin. Pharmacol. (1999) 55(4):269-277.
    • (1999) Eur. J. Clin. Pharmacol. , vol.55 , Issue.4 , pp. 269-277
    • Gehr, T.W.1    Tenero, D.M.2    Boyle, D.A.3    Qian, Y.4    Sica, D.A.5    Shusterman, N.H.6
  • 20
    • 0035131087 scopus 로고    scopus 로고
    • Dilated cardiomyopathy in dialysis patients-beneficial effects of carvedilol: A double-blind, placebo-controlled trial
    • CICE G, FERRARA L, DI BENEDETTO A et al.: Dilated cardiomyopathy in dialysis patients-beneficial effects of carvedilol: a double-blind, placebo-controlled trial. J. Am. Coll. Cardiol. (2001) 37(2):407-411.
    • (2001) J. Am. Coll. Cardiol. , vol.37 , Issue.2 , pp. 407-411
    • Cice, G.1    Ferrara, L.2    Di Benedetto, A.3
  • 21
    • 0024151060 scopus 로고
    • Pharmacokinetics and bioavailability of carvedilol in patients with liver cirrhosis
    • NEUGEBAUER G, GABOR M, REIFF K: Pharmacokinetics and bioavailability of carvedilol in patients with liver cirrhosis. Drugs (1988) 36(Suppl. 6):148-151.
    • (1988) Drugs , vol.36 , Issue.SUPPL. 6 , pp. 148-151
    • Neugebauer, G.1    Gabor, M.2    Reiff, K.3
  • 22
  • 23
    • 0034749793 scopus 로고    scopus 로고
    • Effect of fluoxetine on carvedilol pharmacokinetics, CYP2D6 activity, and autonomic balance in heart failure patients
    • GRAFF DW, WILLIAMSON KM, PIEPER JA et al.: Effect of fluoxetine on carvedilol pharmacokinetics, CYP2D6 activity, and autonomic balance in heart failure patients. J. Clin. Pharmacol. (2001) 41(1):97-106.
    • (2001) J. Clin. Pharmacol. , vol.41 , Issue.1 , pp. 97-106
    • Graff, D.W.1    Williamson, K.M.2    Pieper, J.A.3
  • 24
    • 0025327495 scopus 로고
    • Carvedilol increases the systemic bioavailability of oral digoxin
    • DE MEY C, BRENDEL E, ENTERLING D: Carvedilol increases the systemic bioavailability of oral digoxin. Br. J. Clin. Pharmacol. (1990) 29(4):486-490.
    • (1990) Br. J. Clin. Pharmacol. , vol.29 , Issue.4 , pp. 486-490
    • De Mey, C.1    Brendel, E.2    Enterling, D.3
  • 25
    • 0030721683 scopus 로고    scopus 로고
    • Elevation of cyclosporin A blood levels during carvedilol treatment in renal transplant patients
    • KAIJSER M, JOHNSSON C, ZEZINA L, BACKMAN U, DIMENY E, FELLSTROM B: Elevation of cyclosporin A blood levels during carvedilol treatment in renal transplant patients. Clin. Transplant. (1997) 11(6):577-581.
    • (1997) Clin. Transplant. , vol.11 , Issue.6 , pp. 577-581
    • Kaijser, M.1    Johnsson, C.2    Zezina, L.3    Backman, U.4    Dimeny, E.5    Fellstrom, B.6
  • 26
    • 12144286498 scopus 로고    scopus 로고
    • CYP2D6 genotype and induction of intestinal drug transporters by rifampin predict presystemic clearance of carvedilol in healthy subjects
    • GIESSMANN T, MODESS C, HECKER U et al.: CYP2D6 genotype and induction of intestinal drug transporters by rifampin predict presystemic clearance of carvedilol in healthy subjects. Clin. Pharmacol. Ther. (2004) 75(3):213-222.
    • (2004) Clin. Pharmacol. Ther. , vol.75 , Issue.3 , pp. 213-222
    • Giessmann, T.1    Modess, C.2    Hecker, U.3
  • 27
    • 0042945639 scopus 로고    scopus 로고
    • Beta-blockade in heart failure: Selective versus nonselective agents
    • METRA M, NODARI S, DEI CAS L: Beta-blockade in heart failure: selective versus nonselective agents. Am. J. Cardiovasc. Drugs (2001) 1(1):3-14.
    • (2001) Am. J. Cardiovasc. Drugs , vol.1 , Issue.1 , pp. 3-14
    • Metra, M.1    Nodari, S.2    Dei Cas, L.3
  • 28
    • 0042868378 scopus 로고    scopus 로고
    • Beta-adrenoceptor genotype influences the response to carvedilol in patients with congestive heart failure
    • KAYE DM, SMIRK B, WILLIAMS C, JENNINGS G, ESLER M, HOIST D: Beta-adrenoceptor genotype influences the response to carvedilol in patients with congestive heart failure. Pharmacogenetics (2003) 13(7):379-382.
    • (2003) Pharmacogenetics , vol.13 , Issue.7 , pp. 379-382
    • Kaye, D.M.1    Smirk, B.2    Williams, C.3    Jennings, G.4    Esler, M.5    Hoist, D.6
  • 29
    • 0035499907 scopus 로고    scopus 로고
    • Lack of evidence for peripheral alpha(1)-adrenoceptor blockade during long-term treatment of heart failure with carvedilol
    • KUBO T, AZEVEDO ER, NEWTON GE, PARKER JD, FLORAS JS: Lack of evidence for peripheral alpha(1)-adrenoceptor blockade during long-term treatment of heart failure with carvedilol. J. Am. Coll. Cardiol. (2001) 38(5):1463-1469.
    • (2001) J. Am. Coll. Cardiol. , vol.38 , Issue.5 , pp. 1463-1469
    • Kubo, T.1    Azevedo, E.R.2    Newton, G.E.3    Parker, J.D.4    Floras, J.S.5
  • 30
    • 0029085811 scopus 로고
    • Double-blind, placebo-controlled study of the long-term efficacy of carvedilol in patients with severe chronic heart failure
    • KRUM H, SACKNER-BERNSTEIN JD, GOLDSMITH RL et al.: Double-blind, placebo-controlled study of the long-term efficacy of carvedilol in patients with severe chronic heart failure. Circulation (1995) 92(6):1499-1506.
    • (1995) Circulation , vol.92 , Issue.6 , pp. 1499-1506
    • Krum, H.1    Sackner-Bernstein, J.D.2    Goldsmith, R.L.3
  • 31
    • 0028947523 scopus 로고
    • Carvedilol improves left ventricular function and symptoms in chronic heart figure: A double-blind randomized study
    • OLSEN SL, GILBERT EM, RENLUND DG, TAYLOR DO, YANOWITZ FD, BRISTOW MR: Carvedilol improves left ventricular function and symptoms in chronic heart figure: a double-blind randomized study. J. Am. Coll. Cardiol. (1995) 25(6):1225-1231.
    • (1995) J. Am. Coll. Cardiol. , vol.25 , Issue.6 , pp. 1225-1231
    • Olsen, S.L.1    Gilbert, E.M.2    Renlund, D.G.3    Taylor, D.O.4    Yanowitz, F.D.5    Bristow, M.R.6
  • 32
    • 10544223267 scopus 로고    scopus 로고
    • Carvedilol produces dose-related improvements in left ventricular function and survival in subjects with chronic heart failure
    • MOCHA Investigators
    • BRISTOW MR, GILBERT EM, ABRAHAM WT et al.: Carvedilol produces dose-related improvements in left ventricular function and survival in subjects with chronic heart failure. MOCHA Investigators. Circulation (1996) 94(11):2807-2816.
    • (1996) Circulation , vol.94 , Issue.11 , pp. 2807-2816
    • Bristow, M.R.1    Gilbert, E.M.2    Abraham, W.T.3
  • 33
    • 0031230455 scopus 로고    scopus 로고
    • Safety and efficacy of carvedilol in severe heart failure
    • The US Carvedilol Heart Failure Study Group
    • COHN JN, FOWLER MB, BRISTOW MR et al.: Safety and efficacy of carvedilol in severe heart failure. The US Carvedilol Heart Failure Study Group. J. Card. Fail. (1997) 3(3):173-179.
    • (1997) J. Card. Fail. , vol.3 , Issue.3 , pp. 173-179
    • Cohn, J.N.1    Fowler, M.B.2    Bristow, M.R.3
  • 34
    • 0031050642 scopus 로고    scopus 로고
    • Randomised, placebo-controlled trial of carvedilol in patients with congestive heart failure due to ischaemic heart disease
    • AUSTRALIA/NEW ZEALAND Heart Failure Research Collaborative Group
    • AUSTRALIA/NEW ZEALAND Heart Failure Research Collaborative Group: Randomised, placebo-controlled trial of carvedilol in patients with congestive heart failure due to ischaemic heart disease. Lancet (1997) 349(9049):375-380.
    • (1997) Lancet , vol.349 , Issue.9049 , pp. 375-380
  • 35
    • 0032845314 scopus 로고    scopus 로고
    • Pulmonary function, cardiac function, and exercise capacity in a follow-up of patients with congestive heart failure treated with carvedilol
    • GUAZZI M, AGOSTONI P, MATTURRI M, PONTONE G, GUAZZI MD: Pulmonary function, cardiac function, and exercise capacity in a follow-up of patients with congestive heart failure treated with carvedilol. Am. Heart J. (1999) 138(3 Pt 1):460-467.
    • (1999) Am. Heart J. , vol.138 , Issue.3 PART 1 , pp. 460-467
    • Guazzi, M.1    Agostoni, P.2    Matturri, M.3    Pontone, G.4    Guazzi, M.D.5
  • 36
    • 0030997947 scopus 로고    scopus 로고
    • Left ventricular remodeling with carvedilol in patients with congestive heart failure due to ischemic heart disease
    • Australia-New Zealand Heart Failure Research Collaborative Group
    • DOUGHTY RN, WHALLEY GA, GAMBLE G, MACMAHON S, SHARPE N: Left ventricular remodeling with carvedilol in patients with congestive heart failure due to ischemic heart disease. Australia-New Zealand Heart Failure Research Collaborative Group. J. Am. Coll. Cardiol. (1997) 29(5):1060-1066.
    • (1997) J. Am. Coll. Cardiol. , vol.29 , Issue.5 , pp. 1060-1066
    • Doughty, R.N.1    Whalley, G.A.2    Gamble, G.3    Macmahon, S.4    Sharpe, N.5
  • 37
    • 0036895484 scopus 로고    scopus 로고
    • Effects of carvedilol on left ventricular remodeling and systolic function in elderly patients with heart failure
    • PALAZZUOLI A, BRUNI F, PUCCETTI L et al.: Effects of carvedilol on left ventricular remodeling and systolic function in elderly patients with heart failure. Eur. J. Heart Fail. (2002) 4(6):765-770.
    • (2002) Eur. J. Heart Fail. , vol.4 , Issue.6 , pp. 765-770
    • Palazzuoli, A.1    Bruni, F.2    Puccetti, L.3
  • 38
    • 10544231452 scopus 로고    scopus 로고
    • Carvedilol inhibits clinical progression in patients with mild symptoms of heart failure
    • US Carvedilol Heart Failure Study Group
    • COLUCCI WS, PACKER M, BRISTOW MR et al.: Carvedilol inhibits clinical progression in patients with mild symptoms of heart failure. US Carvedilol Heart Failure Study Group. Circulation (1996) 94(11):2800-2806.
    • (1996) Circulation , vol.94 , Issue.11 , pp. 2800-2806
    • Colucci, W.S.1    Packer, M.2    Bristow, M.R.3
  • 39
    • 10544251442 scopus 로고    scopus 로고
    • Double-blind, placebo-controlled study of the effects of carvedilol in patients with moderate to severe heart failure. The PRECISE Trial. Prospective Randomized Evaluation of Carvedilol on Symptoms and Exercise
    • PACKER M, COLUCCI WS, SACKNER-BERNSTEIN JD et al.: Double-blind, placebo-controlled study of the effects of carvedilol in patients with moderate to severe heart failure. The PRECISE Trial. Prospective Randomized Evaluation of Carvedilol on Symptoms and Exercise. Circulation (1996) 94(11):2793-2799.
    • (1996) Circulation , vol.94 , Issue.11 , pp. 2793-2799
    • Packer, M.1    Colucci, W.S.2    Sackner-Bernstein, J.D.3
  • 40
    • 0035370722 scopus 로고    scopus 로고
    • Comparative effects of carvedilol and metoprolol on left ventricular ejection fraction in heart failure: Results of a meta-analysis
    • PACKER M, ANTONOPOULOS GV, BERLIN JA, CHITTAMS J, KONSTAM MA, UDELSON JE: Comparative effects of carvedilol and metoprolol on left ventricular ejection fraction in heart failure: results of a meta-analysis. Am. Heart J. (2001) 141 (6):899-907.
    • (2001) Am. Heart J. , vol.141 , Issue.6 , pp. 899-907
    • Packer, M.1    Antonopoulos, G.V.2    Berlin, J.A.3    Chittams, J.4    Konstam, M.A.5    Udelson, J.E.6
  • 41
    • 0012806233 scopus 로고    scopus 로고
    • Carvedilol improves diastolic function in patients with diastolic heart failure
    • BERGSTROM A, ANDERSSON B, EDNER M et al.: Carvedilol improves diastolic function in patients with diastolic heart failure. Circulation (2001) 104(17 Suppl. 2):718.
    • (2001) Circulation , vol.104 , Issue.17 SUPPL. 2 , pp. 718
    • Bergstrom, A.1    Andersson, B.2    Edner, M.3
  • 42
    • 0033230514 scopus 로고    scopus 로고
    • Beta-blockade in heart failure: A comparison of carvedilol with metoprolol
    • SANDERSON JE, CHAN SK, YIP G et al.: Beta-blockade in heart failure: a comparison of carvedilol with metoprolol. J. Am. Coll. Cardiol. (1999) 34(5):1522-1528.
    • (1999) J. Am. Coll. Cardiol. , vol.34 , Issue.5 , pp. 1522-1528
    • Sanderson, J.E.1    Chan, S.K.2    Yip, G.3
  • 43
    • 0033602801 scopus 로고    scopus 로고
    • Prospective, randomized comparison of effect of long-term treatment with metoprolol or carvedilol on symptoms, exercise, ejection fraction, and oxidative stress in heart failure
    • KUKIN ML, KALMAN J, CHARNEY RH et al.: Prospective, randomized comparison of effect of long-term treatment with metoprolol or carvedilol on symptoms, exercise, ejection fraction, and oxidative stress in heart failure. Circulation (1999) 99(20):2645-2651.
    • (1999) Circulation , vol.99 , Issue.20 , pp. 2645-2651
    • Kukin, M.L.1    Kalman, J.2    Charney, R.H.3
  • 44
    • 0032693742 scopus 로고    scopus 로고
    • Long-term effects of carvedilol in idiopathic dilated cardiomyopathy with persistent left ventricular dysfunction despite chronic metoprolol
    • The Heart-Muscle Disease Study Group
    • DI LENARDA A, SABBADINI G, SALVATORE L et al.: Long-term effects of carvedilol in idiopathic dilated cardiomyopathy with persistent left ventricular dysfunction despite chronic metoprolol. The Heart-Muscle Disease Study Group. J. Am. Coll. Cardiol. (1999) 33(7):1926-1934.
    • (1999) J. Am. Coll. Cardiol. , vol.33 , Issue.7 , pp. 1926-1934
    • Di Lenarda, A.1    Sabbadini, G.2    Salvatore, L.3
  • 45
    • 0034255060 scopus 로고    scopus 로고
    • Differential effects of beta-blockers in patients with heart failure: A prospective, randomized, double-blind comparison of the long-term effects of metoprolol versus carvedilol
    • METRA M, GIUBBINI R, NODARI S, BOLDI E, MODENA MG, DEI CAS L: Differential effects of beta-blockers in patients with heart failure: A prospective, randomized, double-blind comparison of the long-term effects of metoprolol versus carvedilol. Circulation (2000) 102(5):546-551.
    • (2000) Circulation , vol.102 , Issue.5 , pp. 546-551
    • Metra, M.1    Giubbini, R.2    Nodari, S.3    Boldi, E.4    Modena, M.G.5    Dei Cas, L.6
  • 46
    • 1642494797 scopus 로고    scopus 로고
    • Effects of carvedilol on left ventricular remodelling in patients following acute myocardial infarction: The CAPRICORN echo substudy
    • DOUGHTY RN, WHALLEY GA, WALSH H, GAMBLE G, SHARPE N: Effects of carvedilol on left ventricular remodelling in patients following acute myocardial infarction: the CAPRICORN echo substudy. Circulation (2004) 109(2):201-206.
    • (2004) Circulation , vol.109 , Issue.2 , pp. 201-206
    • Doughty, R.N.1    Whalley, G.A.2    Walsh, H.3    Gamble, G.4    Sharpe, N.5
  • 47
    • 0032958134 scopus 로고    scopus 로고
    • Carvedilol prevents remodeling in patients with left ventricular dysfunction after acute myocardial infarction
    • SENIOR R, BASU S, KINSEY C, SCHAEFFER S, LAHIRI A: Carvedilol prevents remodeling in patients with left ventricular dysfunction after acute myocardial infarction. Am. Heart J. (1999) 137(4 Pt 1):646-652.
    • (1999) Am. Heart J. , vol.137 , Issue.4 PART 1 , pp. 646-652
    • Senior, R.1    Basu, S.2    Kinsey, C.3    Schaeffer, S.4    Lahiri, A.5
  • 48
    • 0034816963 scopus 로고    scopus 로고
    • Regression of left ventricular remodeling in chronic heart failure: Comparative and combined effects of captopril and carvedilol
    • KHATTAR RS, SENIOR R, SOMAN P et al.: Regression of left ventricular remodeling in chronic heart failure: comparative and combined effects of captopril and carvedilol. Am. Heart J. (2001) 142(4):704-713.
    • (2001) Am. Heart J. , vol.142 , Issue.4 , pp. 704-713
    • Khattar, R.S.1    Senior, R.2    Soman, P.3
  • 49
    • 0141852691 scopus 로고    scopus 로고
    • Do patients necessarily have to start with an angiotensin convening enzyme inhibitor in the treatment of heart failure? Results of the CARMEN (Carvedilol ACE inhibitor remodelling mild CHF Evaluation) study
    • REMME WJ, RIEGGER G, HILDEBRANDT P et al.: Do patients necessarily have to start with an angiotensin convening enzyme inhibitor in the treatment of heart failure? Results of the CARMEN (Carvedilol ACE inhibitor remodelling mild CHF Evaluation) study. J. Am. Coll. Cardiol. (2003) 41(6 Suppl. A): 162A.
    • (2003) J. Am. Coll. Cardiol. , vol.41 , Issue.6 SUPPL. A
    • Remme, W.J.1    Riegger, G.2    Hildebrandt, P.3
  • 50
    • 0141628832 scopus 로고    scopus 로고
    • Replacement of angiotensin converting enzyme inhibition by carvedilol results in long-term reversed left ventricular remodeling in mild heart failure and is well tolerated: Results of the CARMEN (Carvedilol ACE-inhibitor Remodeling in Mild Heart Failure Evaluation) study
    • REMME WJ, SOLER-SOLER J, RYDEN L et al.: Replacement of angiotensin converting enzyme inhibition by carvedilol results in long-term reversed left ventricular remodeling in mild heart failure and is well tolerated: results of the CARMEN (Carvedilol ACE-inhibitor Remodeling in Mild Heart Failure Evaluation) study. J. Am. Coll. Cardiol. (2003) 41(6 Suppl. A):205A.
    • (2003) J. Am. Coll. Cardiol. , vol.41 , Issue.6 SUPPL. A
    • Remme, W.J.1    Soler-Soler, J.2    Ryden, L.3
  • 51
    • 0035810547 scopus 로고    scopus 로고
    • Effect of carvedilol on outcome after myocardial infarction in patients with left-ventricular dysfunction: The CAPRICORN randomised trial
    • DARGIE HJ: Effect of carvedilol on outcome after myocardial infarction in patients with left-ventricular dysfunction: the CAPRICORN randomised trial. Lancet (2001) 357(9266):1385-1390.
    • (2001) Lancet , vol.357 , Issue.9266 , pp. 1385-1390
    • Dargie, H.J.1
  • 52
    • 0030835669 scopus 로고    scopus 로고
    • Beneficial effects of intravenous and oral carvedilol treatment in acute myocardial infarction. A placebo-controlled, randomized trial
    • BASU S, SENIOR R, RAVAL U, VAN DER DOES R, BRUCKNER T, LAHIRI A: Beneficial effects of intravenous and oral carvedilol treatment in acute myocardial infarction. A placebo-controlled, randomized trial. Circulation (1997) 96(1):183-191.
    • (1997) Circulation , vol.96 , Issue.1 , pp. 183-191
    • Basu, S.1    Senior, R.2    Raval, U.3    Van Der Does, R.4    Bruckner, T.5    Lahiri, A.6
  • 53
    • 0026779879 scopus 로고
    • Carvedilol, a new vasodilator and beta adrenoceptor antagonist, is an antioxidant and free radical scavenger
    • YUE TL, CHENG HY, LYSKO PG et al.: Carvedilol, a new vasodilator and beta adrenoceptor antagonist, is an antioxidant and free radical scavenger. J. Pharmacol. Exp. Ther. (1992) 263(1):92-98.
    • (1992) J. Pharmacol. Exp. Ther. , vol.263 , Issue.1 , pp. 92-98
    • Yue, T.L.1    Cheng, H.Y.2    Lysko, P.G.3
  • 55
    • 0033951439 scopus 로고    scopus 로고
    • Antioxidant action of the antihypertensive drug, carvedilol, against lipid peroxidation
    • NOGUCHI N, NISHINO K, NIKI E: Antioxidant action of the antihypertensive drug, carvedilol, against lipid peroxidation. Biochem. Pharmacol. (2000) 59(9):1069-1076.
    • (2000) Biochem. Pharmacol. , vol.59 , Issue.9 , pp. 1069-1076
    • Noguchi, N.1    Nishino, K.2    Niki, E.3
  • 56
    • 0035879973 scopus 로고    scopus 로고
    • Radical-scavenging and iron-chelating properties of carvedilol, an antihypertensive drug with antioxidative activity
    • OETTL K, GREILBERGER J, ZANGGER K, HASLINGER E, REIBNEGGER G, JURGENS G: Radical-scavenging and iron-chelating properties of carvedilol, an antihypertensive drug with antioxidative activity. Biochem. Pharmacol. (2001) 62(2):241-248.
    • (2001) Biochem. Pharmacol. , vol.62 , Issue.2 , pp. 241-248
    • Oettl, K.1    Greilberger, J.2    Zangger, K.3    Haslinger, E.4    Reibnegger, G.5    Jurgens, G.6
  • 57
    • 0037129862 scopus 로고    scopus 로고
    • Carvedilol decreases elevated oxidative stress in human failing myocardium
    • NAKAMURA K, KUSANO K, NAKAMURA Y et al.: Carvedilol decreases elevated oxidative stress in human failing myocardium. Circulation (2002) 105(24):2867-2871.
    • (2002) Circulation , vol.105 , Issue.24 , pp. 2867-2871
    • Nakamura, K.1    Kusano, K.2    Nakamura, Y.3
  • 58
    • 0035182486 scopus 로고    scopus 로고
    • Antioxidant properties of carvedilol and metoprolol in heart failure: A double-blind randomised controlled trial
    • ARUMANAYAGAM M, CHAN S, TONG S et al.: Antioxidant properties of carvedilol and metoprolol in heart failure: a double-blind randomised controlled trial. J. Cardiovasc. Pharmacol. (2001) 37(1):48-54.
    • (2001) J. Cardiovasc. Pharmacol. , vol.37 , Issue.1 , pp. 48-54
    • Arumanayagam, M.1    Chan, S.2    Tong, S.3
  • 59
    • 0033979444 scopus 로고    scopus 로고
    • Carvedilol prevents epinephrine-induced apoptosis in human coronary artery endothelial cells: Modulation of Fas/Fas ligand and caspase-3 pathway
    • ROMEO F, LI D, SHI M, MEHTA JL: Carvedilol prevents epinephrine-induced apoptosis in human coronary artery endothelial cells: modulation of Fas/Fas ligand and caspase-3 pathway. Cardiovasc. Res. (2000) 45(3):788-794.
    • (2000) Cardiovasc. Res. , vol.45 , Issue.3 , pp. 788-794
    • Romeo, F.1    Li, D.2    Shi, M.3    Mehta, J.L.4
  • 60
    • 0032498614 scopus 로고    scopus 로고
    • Possible involvement of stress-activated protein kinase signaling pathway and Fas receptor expression in prevention of ischemia/reperfusion-induced cardiomyocyte apoptosis by carvedilol
    • YUE TL, MA XL, WANG X et al.: Possible involvement of stress-activated protein kinase signaling pathway and Fas receptor expression in prevention of ischemia/reperfusion-induced cardiomyocyte apoptosis by carvedilol. Circ. Res. (1998) 82(2):166-174.
    • (1998) Circ. Res. , vol.82 , Issue.2 , pp. 166-174
    • Yue, T.L.1    Ma, X.L.2    Wang, X.3
  • 61
    • 0027529916 scopus 로고
    • Carvedilol inhibits vascular smooth muscle cell proliferation
    • SUNG CR ARLETH AJ, OHLSTEIN EH: Carvedilol inhibits vascular smooth muscle cell proliferation. J. Cardiovasc. Pharmacol. (1993) 21(2):221-227.
    • (1993) J. Cardiovasc. Pharmacol. , vol.21 , Issue.2 , pp. 221-227
    • Sung, C.R.1    Arleth, A.J.2    Ohlstein, E.H.3
  • 62
    • 0028934620 scopus 로고
    • Inhibition of human vascular smooth muscle cell proliferation by the novel multiple-action antihypertensive agent carvedilol
    • PATEL MK, CHAN P, BETTERIDGE LJ, SCHACHTER M, SEVER PS: Inhibition of human vascular smooth muscle cell proliferation by the novel multiple-action antihypertensive agent carvedilol. J. Cardiovasc. Pharmacol. (1995) 25(4):652-657.
    • (1995) J. Cardiovasc. Pharmacol. , vol.25 , Issue.4 , pp. 652-657
    • Patel, M.K.1    Chan, P.2    Betteridge, L.J.3    Schachter, M.4    Sever, P.S.5
  • 63
    • 0001472278 scopus 로고    scopus 로고
    • Carvedilol improves renal hemodynamics in patients with chronic heart failure
    • ABRAHAM WT. TSVETKOVA T: LOWES BD et al.: Carvedilol improves renal hemodynamics in patients with chronic heart failure. Circulation (1998) 98(Suppl. 1):378-379.
    • (1998) Circulation , vol.98 , Issue.SUPPL. 1 , pp. 378-379
    • Abraham, W.T.1    Tsvetkova, T.2    Lowes, B.D.3
  • 64
    • 0042945638 scopus 로고    scopus 로고
    • Improvement of endothelial dysfunction in patients with congestive heart failure during treatment with carvedilol
    • REFSGAARD J, ANDREASEN F, GOETZSCHE O et al.: Improvement of endothelial dysfunction in patients with congestive heart failure during treatment with carvedilol. Eur. Heart J. (1999) 20(Suppl.):375.
    • (1999) Eur. Heart J. , vol.20 , Issue.SUPPL. , pp. 375
    • Refsgaard, J.1    Andreasen, F.2    Goetzsche, O.3
  • 65
    • 0034828069 scopus 로고    scopus 로고
    • Carvedilol increases plasma vascular endothelial growth factor (VEGF) in patients with chronic heart failure
    • DE BOER RA, SIEBELINK HJ, TIO RA, BOOMSMA F, VAN VELDHUISEN DJ: Carvedilol increases plasma vascular endothelial growth factor (VEGF) in patients with chronic heart failure. Eur. J. Heart Fail. (2001) 3(3):331-333.
    • (2001) Eur. J. Heart Fail. , vol.3 , Issue.3 , pp. 331-333
    • De Boer, R.A.1    Siebelink, H.J.2    Tio, R.A.3    Boomsma, F.4    Van Veldhuisen, D.J.5
  • 66
    • 0031893064 scopus 로고    scopus 로고
    • Carvedilol inhibits endothelin-1 biosynthesis in cultured human coronary artery endothelial cells
    • OHLSTEIN EH, ARLETH AJ, STORER B, ROMANIC AM: Carvedilol inhibits endothelin-1 biosynthesis in cultured human coronary artery endothelial cells. J. Mol. Cell. Cardiol. (1998) 30(1):167-173.
    • (1998) J. Mol. Cell. Cardiol. , vol.30 , Issue.1 , pp. 167-173
    • Ohlstein, E.H.1    Arleth, A.J.2    Storer, B.3    Romanic, A.M.4
  • 67
    • 0037090717 scopus 로고    scopus 로고
    • Comparison of effects of carvedilol versus metoprolol on cytokine levels in patients with idiopathic dilated cardiomyopathy
    • OHTSUKA T, HAMADA M, SAEKI H et al.: Comparison of effects of carvedilol versus metoprolol on cytokine levels in patients with idiopathic dilated cardiomyopathy Am. J. Cardiol. (2002) 89(8):996-999.
    • (2002) Am. J. Cardiol. , vol.89 , Issue.8 , pp. 996-999
    • Ohtsuka, T.1    Hamada, M.2    Saeki, H.3
  • 68
    • 0036673266 scopus 로고    scopus 로고
    • Carvedilol does not alter the insulin sensitivity in patients with congestive heart failure
    • REFSGAARD J, THOMSEN C, ANDREASEN F, GOTZSCHE O: Carvedilol does not alter the insulin sensitivity in patients with congestive heart failure. Eur. J. Heart Fail. (2002) 4(4):445-453.
    • (2002) Eur. J. Heart Fail. , vol.4 , Issue.4 , pp. 445-453
    • Refsgaard, J.1    Thomsen, C.2    Andreasen, F.3    Gotzsche, O.4
  • 69
    • 0037097293 scopus 로고    scopus 로고
    • Effect of carvedilol on microcirculatory and glucose metabolic regulation in patients with congestive heart failure secondary to ischemic cardiomyopathy
    • BOTTCHER M, REFSGAARD J, GOTZSCHE O, ANDREASEN F, NIELSEN TT: Effect of carvedilol on microcirculatory and glucose metabolic regulation in patients with congestive heart failure secondary to ischemic cardiomyopathy. Am. J. Cardiol. (2002) 89(12):1388-1393.
    • (2002) Am. J. Cardiol. , vol.89 , Issue.12 , pp. 1388-1393
    • Bottcher, M.1    Refsgaard, J.2    Gotzsche, O.3    Andreasen, F.4    Nielsen, T.T.5
  • 70
    • 0028081393 scopus 로고
    • Effects of short- and long-term carvedilol administration on rest and exercise hemodynamic variables, exercise capacity and clinical conditions in patients with idiopathic dilated cardiomyopathy
    • METRA M, NARDI M, GIUBBINI R, DEI CAS L: Effects of short- and long-term carvedilol administration on rest and exercise hemodynamic variables, exercise capacity and clinical conditions in patients with idiopathic dilated cardiomyopathy. J. Am. Coll. Cardiol. (1994) 24(7):1678-1687.
    • (1994) J. Am. Coll. Cardiol. , vol.24 , Issue.7 , pp. 1678-1687
    • Metra, M.1    Nardi, M.2    Giubbini, R.3    Dei Cas, L.4
  • 71
    • 0037626650 scopus 로고    scopus 로고
    • Myocardial viability as a determinant of the ejection fraction response to carvedilol in patients with heart failure (CHRISTMAS trial): Randomised controlled trial
    • CLELAND JG, PENNELL DJ, RAY SG et al.: Myocardial viability as a determinant of the ejection fraction response to carvedilol in patients with heart failure (CHRISTMAS trial): randomised controlled trial. Lancet (2003) 362(9377):14-21.
    • (2003) Lancet , vol.362 , Issue.9377 , pp. 14-21
    • Cleland, J.G.1    Pennell, D.J.2    Ray, S.G.3
  • 72
    • 0042945637 scopus 로고    scopus 로고
    • Analysis of 24 hour ambulatory ECGs from the CHRISTMAS study
    • MACFARLANE PW, MURRAY GD, MCGOWAN J et al.: Analysis of 24 hour ambulatory ECGs from the CHRISTMAS study. Circulation (2002) 106(19 Suppl.):613.
    • (2002) Circulation , vol.106 , Issue.19 SUPPL. , pp. 613
    • Macfarlane, P.W.1    Murray, G.D.2    Mcgowan, J.3
  • 73
    • 0033915738 scopus 로고    scopus 로고
    • Efficacy of carvedilol on complex ventricular arrhythmias in dilated cardiomyopathy: Double-blind, randomized, placebo-controlled study
    • CICE G, TAGLIAMONTE E, FERRARA L, IACONO A: Efficacy of carvedilol on complex ventricular arrhythmias in dilated cardiomyopathy: double-blind, randomized, placebo-controlled study. Eur. Heart J. (2000) 21(15):1259-1264.
    • (2000) Eur. Heart J. , vol.21 , Issue.15 , pp. 1259-1264
    • Cice, G.1    Tagliamonte, E.2    Ferrara, L.3    Iacono, A.4
  • 74
    • 0029845423 scopus 로고    scopus 로고
    • Comparative hemodynamic, left ventricular functional, and antiadrenergic effects of chronic treatment with metoprolol versus carvedilol in the failing heart
    • GILBERT EM, ABRAHAM WT, OLSEN S et al: Comparative hemodynamic, left ventricular functional, and antiadrenergic effects of chronic treatment with metoprolol versus carvedilol in the failing heart. Circulation (1996) 94(11):2817-2825.
    • (1996) Circulation , vol.94 , Issue.11 , pp. 2817-2825
    • Gilbert, E.M.1    Abraham, W.T.2    Olsen, S.3
  • 75
    • 0034800915 scopus 로고    scopus 로고
    • Prospective crossover comparison of carvedilol and metoprolol in patients with chronic heart failure
    • MAACK C, ELTER T, NICKENIG G et al.: Prospective crossover comparison of carvedilol and metoprolol in patients with chronic heart failure. J. Am. Coll. Cardiol. (2001) 38(4):939-946.
    • (2001) J. Am. Coll. Cardiol. , vol.38 , Issue.4 , pp. 939-946
    • Maack, C.1    Elter, T.2    Nickenig, G.3
  • 76
    • 0029937949 scopus 로고    scopus 로고
    • The effect of carvedilol on morbidity and mortality in patients with chronic heart failure
    • US Carvedilol Heart Failure Study Group
    • PACKER M, BRISTOW MR, COHN JN et al.: The effect of carvedilol on morbidity and mortality in patients with chronic heart failure. US Carvedilol Heart Failure Study Group. N. Engl. J. Med. (1996) 334(21):1349-1355.
    • (1996) N. Engl. J. Med. , vol.334 , Issue.21 , pp. 1349-1355
    • Packer, M.1    Bristow, M.R.2    Cohn, J.N.3
  • 77
    • 0035978763 scopus 로고    scopus 로고
    • Effect of carvedilol on survival in severe chronic heart failure
    • PACKER M, COATS AJ, FOWLER MB et al.: Effect of carvedilol on survival in severe chronic heart failure. N. Engl. J. Med. (2001) 344(22):1651-1658.
    • (2001) N. Engl. J. Med. , vol.344 , Issue.22 , pp. 1651-1658
    • Packer, M.1    Coats, A.J.2    Fowler, M.B.3
  • 78
    • 3142776467 scopus 로고    scopus 로고
    • Comparison of carvedilol and metoprolol on clinical outcomes in patients with chronic heart failure in the Carvedilol Or Metoprolol European Trial (COMET): Randomised controlled trial
    • POOLE-WILSON PA, SWEDBERG K, CLELAND JG et al.: Comparison of carvedilol and metoprolol on clinical outcomes in patients with chronic heart failure in the Carvedilol Or Metoprolol European Trial (COMET): randomised controlled trial. Lancet (2003) 362(9377):7-13.
    • (2003) Lancet , vol.362 , Issue.9377 , pp. 7-13
    • Poole-Wilson, P.A.1    Swedberg, K.2    Cleland, J.G.3
  • 79
    • 0037159310 scopus 로고    scopus 로고
    • Effect of carvedilol on the morbidity of patients with severe chronic heart failure: Results of the carvedilol prospective randomized cumulative survival (COPERNICUS) study
    • PACKER M, FOWLER MB, ROECKER EB et al.: Effect of carvedilol on the morbidity of patients with severe chronic heart failure: results of the carvedilol prospective randomized cumulative survival (COPERNICUS) study. Circulation (2002) 106(17):2194-2199.
    • (2002) Circulation , vol.106 , Issue.17 , pp. 2194-2199
    • Packer, M.1    Fowler, M.B.2    Roecker, E.B.3
  • 80
    • 0037433183 scopus 로고    scopus 로고
    • Effects of initiating carvedilol in patients with severe chronic heart failure: Results from the COPERNICUS Study
    • KRUM H, ROECKER EB, MOHACSI P et al.: Effects of initiating carvedilol in patients with severe chronic heart failure: results from the COPERNICUS Study. JAMA (2003) 289(6):712-718.
    • (2003) JAMA , vol.289 , Issue.6 , pp. 712-718
    • Krum, H.1    Roecker, E.B.2    Mohacsi, P.3
  • 81
    • 0348225238 scopus 로고    scopus 로고
    • A comment on COMET: How to interpret a positive trial?
    • MASSIE BM: A comment on COMET: how to interpret a positive trial? J. Card. Fail. (2003) 9:425-428.
    • (2003) J. Card. Fail , vol.9 , pp. 425-428
    • Massie, B.M.1
  • 82
    • 0346199335 scopus 로고    scopus 로고
    • A clinical pharmacologist's response to Dr Milton Packer's perspective on the results of the COMET trial
    • SHEPHERD AMM: A clinical pharmacologist's response to Dr Milton Packer's perspective on the results of the COMET trial. J. Card. Fail. (2003) 9:454-457.
    • (2003) J. Card. Fail , vol.9 , pp. 454-457
    • Shepherd, A.M.M.1
  • 83
    • 0346199336 scopus 로고    scopus 로고
    • Do β-blockers prolong survival in heart failure only by inhibiting the β1-receptor? A perspective on the results of the COMET trial
    • PACKER M: Do β-blockers prolong survival in heart failure only by inhibiting the β1-receptor? A perspective on the results of the COMET trial. J. Card. Fail. (2003) 9(6):429-443.
    • (2003) J. Card. Fail , vol.9 , Issue.6 , pp. 429-443
    • Packer, M.1
  • 84
    • 0346829866 scopus 로고    scopus 로고
    • Selective versus nonselective β-blockade for heart failure therapy: Are there lessons to be learned from the COMET trial?
    • BRISTOW MR, FELDMAN AM, ADAMS KF JR, GOLDSTEIN S: Selective versus nonselective β-blockade for heart failure therapy: are there lessons to be learned from the COMET trial? J. Card. Fail. (2003) 9(6):444-453.
    • (2003) J. Card. Fail. , vol.9 , Issue.6 , pp. 444-453
    • Bristow, M.R.1    Feldman, A.M.2    Adams Jr., K.F.3    Goldstein, S.4
  • 85
    • 0038501073 scopus 로고    scopus 로고
    • Beta blockers in heart failure
    • DARGIE HJ: Beta blockers in heart failure. Lancet (2003) 362(9377):2-3.
    • (2003) Lancet , vol.362 , Issue.9377 , pp. 2-3
    • Dargie, H.J.1
  • 86
    • 0022980843 scopus 로고
    • β1- and β2-actrenergic receptor subpopulations in non failing and failing human ventricular myocardium: Coupling of both receptor subtypes to muscle contraction and selective β1-receptor down-regulation in heart failure
    • BRISTOW MR, GINSBURG R, UMANS V et al: β1- and β2-actrenergic receptor subpopulations in non failing and failing human ventricular myocardium: coupling of both receptor subtypes to muscle contraction and selective β1-receptor down-regulation in heart failure. Circ. Res. (1986) 59:297-309.
    • (1986) Circ. Res. , vol.59 , pp. 297-309
    • Bristow, M.R.1    Ginsburg, R.2    Umans, V.3
  • 87
    • 33751285021 scopus 로고    scopus 로고
    • Cardiorenal epinephrine kinetics: Evidence for neuronal release in the human heart
    • JOHANSSON M, RUNDQVIST B, EISENHOFER G, FRIBERG P: Cardiorenal epinephrine kinetics: evidence for neuronal release in the human heart. Am. J. Physiol. (1997) 273(5 Pt 2):H2178-H2185.
    • (1997) Am. J. Physiol. , vol.273 , Issue.5 PART 2
    • Johansson, M.1    Rundqvist, B.2    Eisenhofer, G.3    Friberg, P.4
  • 88
    • 0034806747 scopus 로고    scopus 로고
    • Enhanced in vivo and in vitro contractile responses to β2-adrenergic receptor stimulation in dogs susceptible to lethal arrhythmias
    • HOULE MS, ALTSHULD RA, BILLMAN GE: Enhanced in vivo and in vitro contractile responses to β2-adrenergic receptor stimulation in dogs susceptible to lethal arrhythmias. J. Appl. Physiol. (2001) 91:1627-1637.
    • (2001) J. Appl. Physiol. , vol.91 , pp. 1627-1637
    • Houle, M.S.1    Altshuld, R.A.2    Billman, G.E.3
  • 89
    • 0025310770 scopus 로고
    • Selective β1-adrenoceptor blockade enhances positive inotropic responses to endogenous catecholamines mediated through β2-adrenoceptors in human atrial myocardium
    • HALL JA, KAUMANN AJ, BROWN MJ: Selective β1-adrenoceptor blockade enhances positive inotropic responses to endogenous catecholamines mediated through β2-adrenoceptors in human atrial myocardium. Circ. Res. (1990) 66:1610-1623.
    • (1990) Circ. Res. , vol.66 , pp. 1610-1623
    • Hall, J.A.1    Kaumann, A.J.2    Brown, M.J.3
  • 90
    • 0035024537 scopus 로고    scopus 로고
    • Bucindolol, a nonselective beta 1-and beta 2-adrenergic receptor antagonist, decreases beta-adrenergic receptor density in cultured embryonic chick cardiac myocyte membranes
    • ASANO K, ZISMAN LS, YOSHIKAWA T et al.: Bucindolol, a nonselective beta 1-and beta 2-adrenergic receptor antagonist, decreases beta-adrenergic receptor density in cultured embryonic chick cardiac myocyte membranes. J. Cardiovasc. Pharmacol. (2001) 37(6):678-691.
    • (2001) J. Cardiovasc. Pharmacol. , vol.37 , Issue.6 , pp. 678-691
    • Asano, K.1    Zisman, L.S.2    Yoshikawa, T.3
  • 91
    • 3142571368 scopus 로고    scopus 로고
    • Atypical binding of carvedilol to beta adrenoceptors prevents beta blocker rebound phenomenon
    • KINDERMANN M, MAACK C, SCHALLER S et al.: Atypical binding of carvedilol to beta adrenoceptors prevents beta blocker rebound phenomenon. Circulation (2003) 108(Suppl. IV):IV-370.
    • (2003) Circulation , vol.108 , Issue.SUPPL. IV
    • Kindermann, M.1    Maack, C.2    Schaller, S.3
  • 92
    • 0028213385 scopus 로고
    • Positive inotropic effects of the beta 2-adrenoceptor agonist terbutaline in the human heart: Effects of long-term beta 1-adrenoceptor antagonist treatment
    • SCHAFERS RF, ADLER S, DAUL A et al.: Positive inotropic effects of the beta 2-adrenoceptor agonist terbutaline in the human heart: effects of long-term beta 1-adrenoceptor antagonist treatment. J. Am. Coll. Cardiol. (1994) 23(5):1224-1233.
    • (1994) J. Am. Coll. Cardiol. , vol.23 , Issue.5 , pp. 1224-1233
    • Schafers, R.F.1    Adler, S.2    Daul, A.3
  • 93
    • 3042671609 scopus 로고    scopus 로고
    • Lack of heart rate effects on the mortality benefits of carvedilol compared to metoprolol in the patients with heart failure: Results from the Carvedilol or Metoprolol European Trial (COMET)
    • METRA M, CLELAND JG, DI LENARDA A et al.: Lack of heart rate effects on the mortality benefits of carvedilol compared to metoprolol in the patients with heart failure: results from the Carvedilol or Metoprolol European Trial (COMET). J. Am. Coll. Cardiol. (2004) 43 (5 Suppl. A):157A.
    • (2004) J. Am. Coll. Cardiol. , vol.43 , Issue.5 SUPPL. A
    • Metra, M.1    Cleland, J.G.2    Di Lenarda, A.3
  • 94
    • 3042622589 scopus 로고    scopus 로고
    • Beta-blocker dose does not influence the beneficial effects of carvedilol compared to metoprolol in the patients with heart failure: Results from the Carvedilol or Metoprolol European Trial (COMET)
    • METRA M, POOLE-WILSON PA, CLELAND JG et al.: Beta-blocker dose does not influence the beneficial effects of carvedilol compared to metoprolol in the patients with heart failure: results from the Carvedilol or Metoprolol European Trial (COMET). J. Am. Coll. Cardiol. (2004) 43(5 Suppl. A): 206A.
    • (2004) J. Am. Coll. Cardiol. , vol.43 , Issue.5 SUPPL. A
    • Metra, M.1    Poole-Wilson, P.A.2    Cleland, J.G.3
  • 95
    • 0032558449 scopus 로고    scopus 로고
    • Clinical effects of beta-adrenergic blockade in chronic heart failure: A meta-analysis of double-blind, placebo-controlled, randomized trials
    • LECHAT P, PACKER M, CHALON S, CUCHERAT M, ARAB T, BOISSEL JP: Clinical effects of beta-adrenergic blockade in chronic heart failure: a meta-analysis of double-blind, placebo-controlled, randomized trials. Circulation (1998) 98(12):1184-1191.
    • (1998) Circulation , vol.98 , Issue.12 , pp. 1184-1191
    • Lechat, P.1    Packer, M.2    Chalon, S.3    Cucherat, M.4    Arab, T.5    Boissel, J.P.6
  • 96
    • 0030941991 scopus 로고    scopus 로고
    • Effects of beta-blocker therapy on mortality in patients with heart failure. A systematic overview of randomized controlled trials
    • DOUGHTY RN, RODGERS A, SHARPE N, MACMAHON S: Effects of beta-blocker therapy on mortality in patients with heart failure. A systematic overview of randomized controlled trials. Eur. Heart J. (1997) 18(4):560-565.
    • (1997) Eur. Heart J. , vol.18 , Issue.4 , pp. 560-565
    • Doughty, R.N.1    Rodgers, A.2    Sharpe, N.3    Macmahon, S.4
  • 97
    • 0001648213 scopus 로고    scopus 로고
    • Safety and tolerability of carvedilol in patients with severe chronic heart failure: Results of the COPERNICUS study
    • KRUM H, COATS AJ, FOWLER MB et al.: Safety and tolerability of carvedilol in patients with severe chronic heart failure: results of the COPERNICUS study. Circulation (2001) 104(17 Suppl.):717.
    • (2001) Circulation , vol.104 , Issue.17 SUPPL. 717 , pp. 717
    • Krum, H.1    Coats, A.J.2    Fowler, M.B.3
  • 98
    • 3142637396 scopus 로고    scopus 로고
    • Exchange of beta-blocking therapy in heart failure patients. Experiences from the post-study phase of COMET (The Carvedilol or Metoprolol European Trial)
    • for the COMET INVESTIGATORS (In Press)
    • DI LENARDA A, POOLE-WILSON PA, CLELAND JG et al., for the COMET INVESTIGATORS: Exchange of beta-blocking therapy in heart failure patients. Experiences from the post-study phase of COMET (The Carvedilol or Metoprolol European Trial). J. Am. Coll. Cardiol. (In Press).
    • J. Am. Coll. Cardiol.
    • Di Lenarda, A.1    Poole-Wilson, P.A.2    Cleland, J.G.3
  • 99
    • 17944374924 scopus 로고    scopus 로고
    • Guidelines for the diagnosis and treatment of chronic heart failure
    • for the Task Force For The Diagnosis And Treatment Of Chronic Heart Failure, European Society of Cardiology:
    • REMME WJ, SWEDBERG K, for the Task Force For The Diagnosis And Treatment Of Chronic Heart Failure, European Society of Cardiology: guidelines for the diagnosis and treatment of chronic heart failure. Eur. Heart J. (2001) 22(17):1527-1560.
    • (2001) Eur. Heart J. , vol.22 , Issue.17 , pp. 1527-1560
    • Remme, W.J.1    Swedberg, K.2
  • 100
    • 0035846616 scopus 로고    scopus 로고
    • ACC/AHA Guidelines for the evaluation and management of chronic heart failure in the adult: Executive summary. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to revise the 1995 Guidelines for the evaluation and management of heart failure)
    • HUNT SA, BAKER DW, CHIN MH et al.: ACC/AHA Guidelines for the evaluation and management of chronic heart failure in the adult: executive summary. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to revise the 1995 Guidelines for the evaluation and management of heart failure): developed in collaboration with the International Society for Heart and Lung Transplantation; endorsed by the Heart Failure Society of America. Circulation (2001) 104(24):2996-3007.
    • (2001) Circulation , vol.104 , Issue.24 , pp. 2996-3007
    • Hunt, S.A.1    Baker, D.W.2    Chin, M.H.3
  • 101
    • 0033549290 scopus 로고    scopus 로고
    • Effect of meroprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervention Trial in Congestive Heart Failure (MERIT-HF)
    • MERIT-HF STUDY GROUP
    • MERIT-HF STUDY GROUP: Effect of meroprolol CR/XL in chronic heart failure: metoprolol CR/XL Randomised Intervention Trial in Congestive Heart Failure (MERIT-HF). Lancet (1999) 353(9169):2001-2007.
    • (1999) Lancet , vol.353 , Issue.9169 , pp. 2001-2007
  • 102
    • 0034104565 scopus 로고    scopus 로고
    • Effects of controlled-release metoprolol on total mortality, hospitalizations, and well-being in patients with heart failure: The Metoprolol CR/XL Randomized Intervention Trial in congestive heart failure (MERIT-HF)
    • MERIT-HF Study Group
    • HJALMARSON A, GOLDSTEIN S, FAGERBERG B et al.: Effects of controlled-release metoprolol on total mortality, hospitalizations, and well-being in patients with heart failure: the Metoprolol CR/XL Randomized Intervention Trial in congestive heart failure (MERIT-HF). MERIT-HF Study Group. JAMA (2000) 283(10):1295-1302.
    • (2000) JAMA , vol.283 , Issue.10 , pp. 1295-1302
    • Hjalmarson, A.1    Goldstein, S.2    Fagerberg, B.3
  • 103
    • 0033514046 scopus 로고    scopus 로고
    • The Cardiac Insufficiency Bisoprolol Study II (CIBIS-II): A randomised trial
    • CIBIS-II INVESTIGATORS AND COMMITTEES
    • CIBIS-II INVESTIGATORS AND COMMITTEES: The Cardiac Insufficiency Bisoprolol Study II (CIBIS-II): a randomised trial. Lancet (1999) 353(9146):9-13.
    • (1999) Lancet , vol.353 , Issue.9146 , pp. 9-13
  • 104
    • 0032552240 scopus 로고    scopus 로고
    • Effect of beta-blockade on mortality among high-risk and low-risk patients after myocardial infarction
    • GOTTLIEB SS, MCCARTER RJ, VOGEL RA: Effect of beta-blockade on mortality among high-risk and low-risk patients after myocardial infarction. N. Engl. J. Med. (1998) 339(8):489-497.
    • (1998) N. Engl. J. Med. , vol.339 , Issue.8 , pp. 489-497
    • Gottlieb, S.S.1    Mccarter, R.J.2    Vogel, R.A.3
  • 105
    • 0035821326 scopus 로고    scopus 로고
    • Practical aspects of using beta-adrenergic blockade in systolic heart failure
    • GHEORGHIADE M, EICHHORN EJ. Practical aspects of using beta-adrenergic blockade in systolic heart failure. Am. J. Med. (2001) 110(Suppl. 7A):68S-73S.
    • (2001) Am. J. Med. , vol.110 , Issue.SUPPL. 7A
    • Gheorghiade, M.1    Eichhorn, E.J.2
  • 106
    • 0037380626 scopus 로고    scopus 로고
    • Beta-blockers in chronic heart failure
    • GHEORGHIADE M, COLUCCI WS, SWEDBERG K: Beta-blockers in chronic heart failure. Circulation (2003) 107(12):1570-1575.
    • (2003) Circulation , vol.107 , Issue.12 , pp. 1570-1575
    • Gheorghiade, M.1    Colucci, W.S.2    Swedberg, K.3
  • 107
    • 0029998396 scopus 로고    scopus 로고
    • Differential effect of chronic treatment with two beta-blocking agents on insulin sensitivity: The carvedilol-metoprolol study
    • JACOB S, RETT K, WICKLMAYR M, AGRAWAL B, AUGUSTIN HJ, DIETZE GJ: Differential effect of chronic treatment with two beta-blocking agents on insulin sensitivity: the carvedilol-metoprolol study. J. Hypertens. (1996) 14(4):489-494.
    • (1996) J. Hypertens. , vol.14 , Issue.4 , pp. 489-494
    • Jacob, S.1    Rett, K.2    Wicklmayr, M.3    Agrawal, B.4    Augustin, H.J.5    Dietze, G.J.6
  • 108
    • 0030943599 scopus 로고    scopus 로고
    • Metabolic and cardiovascular effects of carvedilol and atenolol in non-insulin-dependent diabetes mellitus and hypertension. A randomized, controlled trial
    • GIUGLIANO D, ACAMPORA R, MARFELLA R et al.: Metabolic and cardiovascular effects of carvedilol and atenolol in non-insulin-dependent diabetes mellitus and hypertension. A randomized, controlled trial. Ann. Intern. Med. (1997) 126(12):955-959.
    • (1997) Ann. Intern. Med. , vol.126 , Issue.12 , pp. 955-959
    • Giugliano, D.1    Acampora, R.2    Marfella, R.3


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