Segmental duplication density decrease with distance to human-mouse breaks of synteny

European Journal of Human Genetics

Volumn 14, Issue 2, 2006, Pages 216-221

  Sainz, Jesus ^a   Rovensky, Pavol ^a   Gudjonsson, Sigurjon A ^a   Thorleifsson, Gudmar ^a   Stefansson, Kari ^a   Gulcher, Jeffrey R ^a  

^a DECODE GENETICS   (Iceland)

Author keywords

Evolution; Segmental duplications; Synteny

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; ARTIFACT REDUCTION; BIOINFORMATICS; CHROMOSOME DUPLICATION; COMPUTER ANALYSIS; CONTROLLED STUDY; CORRELATION ANALYSIS; GENE FREQUENCY; GENE SEQUENCE; GENOME ANALYSIS; HUMAN; HUMAN VERSUS ANIMAL COMPARISON; MOUSE; NONHUMAN; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SYNTENY;

ANIMALS; COMPUTATIONAL BIOLOGY; EVOLUTION, MOLECULAR; GENE DUPLICATION; GENOME; GENOMICS; HUMANS; MICE; SPECIES SPECIFICITY; SYNTENY;

ANIMALIA;

EID: 31344474496     PISSN: 10184813     EISSN: 14765438     Source Type: Journal    
DOI: 10.1038/sj.ejhg.5201534     Document Type: Article

References (23)

1. Ohno S, Wolf U, Atkin NB: Evolution from fish to mammals by gene duplication. Hereditas 1968; 59: 169-187.
2. Lander ES, Linton LM, Birren B et al: Initial sequencing and analysis of the human genome. Nature 2001; 409: 860-921.
3. Waterston RH, Lindblad-Toh K, Birney E et al: Initial sequencing and comparative analysis of the mouse genome. Nature 2002; 420: 520-562.
4. Cheung VG, Nowak N, Jang W et al: Integration of cytogenetic landmarks into the draft sequence of the human genome. Nature 2001; 409: 953-958.
5. Bailey JA, Gu Z, Clark RA et al: Recent segmental duplications in the human genome. Science 2002; 297: 1003-1007.
6. Cheung J, Estivill X, Khaja R et al: Genome-wide detection of segmental duplications and potential assembly errors in the human genome sequence. Genome Biol 2003; 4: R25.
7. Gratacos M, Nadal M, Martin-Santos R et al: A polymorphic genomic duplication on human chromosome 15 is a susceptibility factor for panic and phobic disorders. Cell 2001; 106: 367-379.
8. Mazzarella R, Schlessinger D: Pathological consequences of sequence duplications in the human genome. Genome Res 1998; 8: 1007-1021.
9. Emanuel BS, ShaikhATH: Segmental duplications: an 'expanding' role in genomic instability and disease. Nat Rev Genet 2001; 2: 791-800.
10. Stankiewicz P, Lupski JR: Genome architecture, rearrangements and genomic disorders. Trends Genet 2002; 18: 74-82.
11. Singleton AB, Farrer M, Johnson J et al: Alpha-Synuclein locus triplication causes Parkinson's disease. Science 2003; 302: 841.
12. Samonte RV, Eichler EE: Segmental duplications and the evolution of the primate genome. Nat Rev Genet 2002; 3: 65-72.
13. Eichler EE: Recent duplication, domain accretion and the dynamic mutation of the human genome. Trends Genet 2001; 17: 661-669.
14. Goidts V, Szamalek JM, Hameister H, Kehrer-Sawatzki H: Segmental duplication associated with the human-specific inversion of chromosome 18: A further example of the impact of segmental duplications on karyotype and genome evolution in primates. Hum Genet 2004; 115: 116-122.
15. Skaletsky H, Kuroda-Kawaguchi T, Minx PJ et al: The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes. Nature 2003; 423: 825-837.
16. Rozen S, Skaletsky H, Marszalek JD et al: Abundant gene conversion between arms of palindromes in human and ape Y chromosomes. Nature 2003; 423: 873-876.
17. Dehal P, Predki P, Olsen AS et al: Human chromosome 19 and related regions in mouse: Conservative and lineage-specific evolution. Science 2001; 293: 104-111.
18. Armengol L, Pujana MA, Cheung J, Scherer SW, Estivill X: Enrichment of segmental duplications in regions of breaks of synteny between the human and mouse genomes suggest their involvement in evolutionary rearrangements. Hum Mol Genet 2003; 12: 2201-2208.
19. Kent WJ: BLAT - the BLAST-like alignment tool. Genome Res 2002; 12: 656-664.
20. Bailey JA, Yavor AM, Viggiano L et al: Human-specific duplication and mosaic transcripts: The recent paralogous structure of chromosome 22. Am J Hum Genet 2002; 70: 83-100.
21. Gregory SG, Sekhon M, Schein J et al: A physical map of the mouse genome. Nature 2002; 418: 743-750.
22. She X, Jiang Z, Clark RA et al: Shotgun sequence assembly and recent segmental duplications within the human genome. Nature 2004; 431: 927-930.
23. Navarro A, Barton NH: Chromosomal speciation and molecular divergence - accelerated evolution in rearranged chromosomes. Science 2003; 300: 321-324.