Divergent effects of bicuculline and picrotoxin on ketamine-induced apneustic breathing

Journal of Physiology and Pharmacology

Volumn 56, Issue SUPPL. 4, 2005, Pages 39-46

  Budzinska K ^a  

^a MOSSAKOWSKI MEDICAL RESEARCH CENTRE   (Poland)

Author keywords

Apneustic pattern; Bicuculline; Ketamine; Picrotoxin

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; 4 AMINOBUTYRIC ACID RECEPTOR BLOCKING AGENT; BICUCULLINE METHIODIDE; KETAMINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; PICROTOXIN; RECEPTOR SUBUNIT;

ANESTHESIA INDUCTION; ANIMAL EXPERIMENT; ANIMAL MODEL; APNEA; APNEUSTIC BREATHING; ARTICLE; ARTIFICIAL VENTILATION; BREATHING PATTERN; CAT; CONTROLLED STUDY; DRUG EFFECT; INSPIRATORY CAPACITY; NEUROTRANSMISSION; NONHUMAN; PARALYSIS; PROTEIN FUNCTION; SENSITIVITY ANALYSIS;

ANIMALS; APNEA; BICUCULLINE; BLOOD PRESSURE; CATS; DISEASE MODELS, ANIMAL; GABA ANTAGONISTS; INHALATION; INJECTIONS, INTRAVENOUS; KETAMINE; PHRENIC NERVE; PICROTOXIN; RECEPTORS, GABA-A; RESPIRATORY MECHANICS;

EID: 31344439816     PISSN: 08675910     EISSN: 08675910     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Foutz AS, Champagnat J, Denavit-Saubie M. N-methyl-D-aspartate NMDA receptors control respiratory off-switch in cat. Neurosci Lett 1988; 87: 221-226.
2. A receptor mediated fast synaptic inhibition in the rabbit brain-stem respiratory system. Acta Physiol Scand 1991; 142: 411- 420.
3. Hayashi F, Lipski J. The role of inhibitory amino acids in control of respiratory motor output in an arterially perfused rat. Respir Physiol 1992; 89: 47-63.
4. Lin LH, Chen LL, Zirrolli JA, Harris RA. General anaesthetics potentiate γ-aminobutyric acid actions on γ-aminobutyric acid A receptors expressed by Xenopus oocytes: lack of involvement of intracellular calcium. J Pharm Exp Ther 1992; 263: 569-578.
5. Suria A, Rasheed F. Evidence for involvement of amino acid neurotransmitters in anaesthesia and naloxone induced reversal of respiratory paralysis. Life Sci 1994; 54: 2021-2033.
6. Vallin A, Voltz C, Naquet R, Lloyd KG. Effects of pharmacological manipulation on neurotransmitter and other amino acid levels in the CSF of the Senegalese baboon Papio Papio. Brain Res 1991; 538: 15-23.
7. A receptor-mediated inhibition Anesthesiology 2000; 92: 1067-1073.
8. Little HJ, Clark A, Watson WP. Investigations into pharmacological antagonism of general anaesthesia Brit J Pharmacol 2000; 129: 1755-1763
9. Blennow G, Folbergrova J, Nilsson B, Siesjo BK. Cerebral metabolic and circulatory changes in the rat during sustained seizures induced by DL-homocysteine. Brain Res 1979; 179: 129-146.
10. Krolo M, Stuth EA, Tonkovic-Capin M, Hopp FA, Mc Crimmon DR, Zuperku EJ. Relative magnitude of tonic and phasic synaptic excitation of medullary inspiratory neurons in dogs. Am J Physiol 2000; 279: R639-R649
11. Pierrefiche O, Foutz AS, Champagnat J, Denavit-Saubie M. The bulbar network of respiratory neurons during apneusis induced by a blockade of NMDA receptors. Exp Brain Res 1992; 89: 623-639.
12. Flood P, Krasowski MD. Intravenous anesthetics differentially modulate ligand-gated ion channels. Anesthesiology 2000; 92: 1418-1425.
13. A receptor agonistic properties of ketamine: convulsive and anesthetic behavioral models in mice. Anesth Analg 2000; 91: 230-236.
14. Gage PW, Robertson B. Prolongation of inhibitory postsynaptic currents by pentobarbitone, halothane and ketamine in CA1 pyramidal cells in rat hippocampus. Br J Pharmacol 1985; 85:675-681.
15. Wakasugi M, Hirota K, Roth SH, Ito Y. The effects of general anesthetics on excitatory and inhibitory synaptic transmission in area CA1 of the rat hippocampus in vitro. Anesth Analg 1999; 88: 676-680.
16. Akaike N, Hattori Y, Oomura, Carpenter DO. Bicuculline and picrotoxin block γ-aminobutyric acid gated Cl- conductance by different mechanism. Experientia 1985; 41: 71-72.
17. Zhang H-G, Lee H-J, Rocheleau T, French-Constant RH, Jackson MB. Subunit composition determinates picrotoxin and bicuculline sensitivity of Drosophila γ-aminobutyric acid receptors. Mol Pharmacol 1995; 48: 835-840.
18. C receptors. Trends Neurosci 1995; 18: 515-519.
19. A receptor antagonists in the control of respiratory neuronal discharge patterns. J Neurophysiol 1998; 80: 2368-2377.
20. A receptors shape the discharge pattern of bulbar respiratory neurons. Brain Res 1996; 710: 150-160.
21. Krolo M, Stuth EA, Tonkovic-Capin M et al. Differential role ionotropic glutamate receptors in canine medullary inspiratory neurons of the ventral respiratory group. J Neurophysiol 1999; 82: 60-68.
22. Ozbek H, Bilen A, Ozcengiz D, Gunes Y, Ozalevli M, Akman H. The comparison of caudal ketamine, alfentanil and ketamine plus alfentanil administration for postoperative analgesia in children. Paediatr Anaesth 2002; 2: 610-616.
23. Durieux ME. Inhibition by ketamine of muscarinic acetylcholine receptor function. Anesth Analg 1995; 81: 57-62.
24. Lydic R, Baghdoyan HA. Ketamine and MK-801 decrease acetylcholine release in the pontine reticular formation, slow breathing, and disrupt sleep. Sleep 2002; 25: 617-622.
25. Suzuki T, Takagi R, Kawashima K. Picrotoxin increased acetylcholine release from rat cultured embryonic septal neurons. Neurosci Lett 2004; 356: 57-60
26. C receptors to acetylcholine release and directional selectivity in the rabbit retina. Vis Neurosci 1997; 14: 939-948.
27. Cumming JF. The development of an acute tolerance to ketamine. Anesth Analg 1976; 55: 788-791.