Antimalarial activity of methylpiperazinyl-substituted benzophenone-based farnesyltransferase inhibitors

Pharmazie

Volumn 61, Issue 1, 2006, Pages 63-65

  Kettler, K ^a   Wiesner, J ^b   Ortmann, R ^a   Dahse, H M ^c   Jomaa, H ^b   Schlitzer, Martin ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b JUSTUS LIEBIG UNIVERSITY   (Germany)

^c HANS KNÖLL INSTITUTE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMALARIAL AGENT; BENZOPHENONE DERIVATIVE; CHLOROQUINE; CYCLOGUANIL; N [3 BENZOYL 4 [2 (4 CHLOROPHENYL)(4 METHYL 1 PIPERAZINYL)ACETYLAMINO]PHENYL] 3 [5 (4 METHYLSULFONYLPHENYL) 2 FURYL]ACRYLIC ACID AMIDE; N [3 BENZOYL 4 [2 (4 METHYL 1 PIPERAZINYL) 2 PHENYLACETYLAMINO]PHENYL] 3 [5 (4 CHLOROPHENYL) 2 FURYL]ACRYLIC ACID AMIDE; N [3 BENZOYL 4 [2 (4 METHYL 1 PIPERAZINYL) 2 PHENYLACETYLAMINO]PHENYL] 3 [5 (4 METHYLSULFONYLPHENYL) 2 FURYL]ACRYLIC ACID AMIDE; PIPERAZINE DERIVATIVE; PROTEIN FARNESYLTRANSFERASE INHIBITOR; PYRIMETHAMINE; UNCLASSIFIED DRUG;

ANTIMALARIAL ACTIVITY; ARTICLE; DRUG CYTOTOXICITY; DRUG DETERMINATION; DRUG SELECTIVITY; HUMAN; HUMAN CELL; IC 50; NONHUMAN; PLASMODIUM FALCIPARUM; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTIMALARIALS; BENZOPHENONES; CELL SURVIVAL; ENZYME INHIBITORS; FARNESYLTRANSTRANSFERASE; GLUTATHIONE TRANSFERASE; HELA CELLS; HUMANS; INDICATORS AND REAGENTS; MAGNETIC RESONANCE SPECTROSCOPY; PIPERAZINES; PLASMODIUM FALCIPARUM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 31144451267     PISSN: 00317144     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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