Vitamin status and cognitive function in a long-term care population

BMC Geriatrics

Volumn 5, Issue , 2005, Pages

  Paulionis, Lina ^a,b   Kane, Sheri Lynn ^a,b   Meckling, Kelly A ^a,b  

^a UNIVERSITY OF GUELPH   (Canada)

^b St Joseph's Hospital and Home   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

COBALAMIN; CYANOCOBALAMIN; FOLIC ACID; HOMOCYSTEINE; NICOTINAMIDE; NICOTINIC ACID; NIZATIDINE; OMEPRAZOLE; PYRIDOXAL 5 PHOSPHATE; PYRIDOXINE; RANITIDINE; VITAMIN;

ADULT; AGED; ARTICLE; BLOOD SAMPLING; CANADA; COGNITION; CONTROLLED STUDY; FEMALE; HOSPITAL CARE; HUMAN; LONG TERM CARE; MAJOR CLINICAL STUDY; MALE; MENTAL HEALTH; METABOLISM; POPULATION; PREVALENCE; STOMACH ACID; VITAMIN BLOOD LEVEL; VITAMIN DEFICIENCY; VITAMIN SUPPLEMENTATION; BLOOD; COGNITION DISORDERS; CROSS-SECTIONAL STUDY; MIDDLE AGED; NUTRITIONAL STATUS; VERY ELDERLY;

AGED; AGED, 80 AND OVER; COGNITION DISORDERS; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; LONG-TERM CARE; MALE; MIDDLE AGED; NUTRITIONAL STATUS; VITAMINS;

EID: 30944451366     PISSN: 14712318     EISSN: 14712318     Source Type: Journal    
DOI: 10.1186/1471-2318-5-16     Document Type: Article

References (51)

1. Goodwin JS, Goodwin JM, Garry P: Association between nutritional status and cognitive functioning in a healthy elde rly population. JAMA 1983, 249:2917-2921.
2. Ortega RM, Requejo AM, Andres P, Lopez-Sobaler AM, Quintas ME, Redondo MR, Navia B, Rivas T: Dietary intake and cognitive function in a group of elderly people. Am J Clin Nutr 1997, 66:803-809.
3. La Rue A, Koehler KM, Wayne SJ, Chiulli SJ, Haaland KY, Garry PJ: Nutritional status and cognitive functioning in a normally aging sample: a 6-y reassessment. Am J Clin Nutr 1997, 65:20-29.
4. Greenwood CE, Winocur G: Decline in cognitive function with aging: impact of diet. Mature Medicine 1999:205-209.
5. Raskind M: Nutrition and cognitive function in the elderly. JAMA 1983, 249:2939-2940.
6. Bell IR, Edman JS, Miller J, Hebben N, Linn RT, Ray D, Kayne HL: Relationship of normal serum vitamin B12 and folate levels to cognitive test performance in subtypes of geriatric major depression. J Geriatr Psychiatry Neurol 1990, 3:98-105.
7. Driskell JA: Vitamin B6 requirements of humans. Nutr Res 1994, 14:293-324.
8. Riggs KM, Spiro A 3rd, Tucker K, Rush D: Relations of vitamin B12, vitamin B6, folate, and homocysteine to cognitive performance in the Normative Aging Study. Am J Clin Nutr 1996, 63:306-314.
9. Clarke R, Smith AD, Jobst KA, Refsum H, Sutton L, Ueland PM: Folate, vitamin B12 and serum total homocysteine levels in confirmed Alzheimer disease. Arch Neurol 1998, 55:1449-1455.
10. McCaddon A, Davies G, Hudson P, Tandy S, Cattell H: Total serum homocysteine in senile dementia of Alzheimer Type. Int J Geriat Psychiatry 1998, 13:235-239.
11. Kasper H: Vitamin Absorption in the Elderly. Int J Vitam Nutr Res 1999, 69:169-172.
12. Baik HW, Russell RM: Vitamin B12 deficiency in the elderly. Annu Rev Nutr 1999, 19:357-377.
13. Van den Berg H: Vitamin B6 status and requirements in older adults. Brit J Nutr 1999, 81:175-176.
14. Rose CS, Gyorgy P, Butler M, Andres R, Norris AH, Shock NW, Tobin J, Brin M, Spiegel H: Age differences in vitamin B6 status of 617 men. Am J Clin Nutr 1976, 29:847-853.
15. Krasinski SD, Russell RM, Samloff IM, Jacob RA, Dallal GE, McGandy RB, Hartz SC: Fundic atrophic gastritis in an elderly population: effect on hemoglobin and several serum nutritional indicators. J Am Geriatr Soc 1986, 34:S00-S06.
16. Bradford GS, Taylor CT: Omeprazole and Vitamin B12 deficiency. Annals Pharmacotherapy 1999, 33:641-643.
17. Russell RM: The aging process as a modifier of metabolism. Am J Clin Nutr 2000, 72(suppl):529S-532S.
18. Pennypacker LC, Allen RH, Kelly JP, Matthews LM, Grigsby J, Kaye K, Lindenbaum J, Stabler SP: High prevalence of cobalamin deficiency in elderly outpatients. J Am Geriatr Soc 1992, 40:1197-1204.
19. Selhub J: Homocysteine metabolism. Annu Rev Nutr 1999, 19:217-246.
20. Diaz-Arrastia R: Homocysteine and neurologic disease. Arch Neurol 2000, 57:1422-1428.
21. Molloy W: Standardized Mini-Mental State Examination. New Grange Press, Canada; 1999.
22. Joosten E, Lesaffre R, Riezler R: Are different reference intervals for methylmalonic acid and total homocysteine necessary in elderly people. Eur J Haematol 1996, 57:222-226.
23. Ortega RM, Manas LR, Andres P, Gaspar MJ, Agudo FR, Jimenez A, Pascual T: Functional and psychic deterioration in elderly people may be aggravated by folate deficiency. J Nutr 1996, 126:1992-1999.
24. Jacobson EL, Jacobson MK: Tissue NAD as a biochemical measure of niacin status in humans. Methods Enzymol 1997, 280:221-230.
25. Camilo E, Zimmerman J, Mason JB, Golner B, Russell R, Selhub J, Rosenberg IH: Folate synthesized by bacteria in the human upper small intestine is assimilated by the host. Gastroenterol 1996, 110:991-998.
26. Joosten E, van den Berg A, Riezler R, Naurath HJ, Lindenbaum J, Stabler SP, Allen RH: Metabolic evidence that deficiencies of vitamin B12 (cobalamin), folate, and vitamin B6 occur commonly in elderly people. Am J Clin Nutr 1993, 58:468-476.
27. Jacobson EL, Shieh WM, Huang AC: Mapping the role of NAD metabolism in prevention and treatment of carcinogenesis. Mol Cell Biochem 1999, 193:69-74.
28. Fu CS, Swendseid ME, Jacob RA, McKee RW: Biochemical markers for assessment of niacin status in young men: levels of erythrocyte niacin coenzymes and plasma tryptophan. J Nutr 1989, 119:1949-1955.
29. Knebl JA, Jacobson EL: Assessment of niacin status in an elderly population. The Gerontologist 1992, 32:247A.
30. Jacobson E: Niacin deficiency and cancer in women. J Am Coll Nutr 1993, 12:412-416.
31. Holleland G, Schneede J, Ueland PM, Lund PK, Refsum H, Sandberg S: Cobalamin deficiency in general practice. Assessment of the diagnostic utility and cost-benefit analysis of methylmalonic acid determination in relation to current diagnostic strategies. Clin Chem 1999, 45:189-198.
32. Yao Y, Yao SL, Yao SS, Yao G, Lou W: Prevalence of vitamin B12 deficiency among geriatric outpatients. J Fam Pract 1992, 35:524-528.
33. Termanini B, Gibril F, Sutliff VE, Yu F, Venzon DJ, Jensen RT: Effect of long-term gastric acid suppressive therapy on serum vitamin B12 levels in patients with Zollinger-Ellison syndrome. Am J Med 1998, 104:422-430.
34. Clissold SP, Campoli-Richards DM: Omeprazole: a preliminary review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential on peptic ulcer disease and Zollinger-Ellison syndrome. Drugs 1986, 32:15-47.
35. Lanzon-Miller S, Pounder RE, Hamilton MR, Ball S, Chronos NA, Raymond F, Olausson M, Cederberg C: Twenty-four-hour intragastric acidity and plasma gastrin concentration before and during treatment with either ranitidine or omeprazole. Aliment Pharmacol Ther 1987, 1:239-251.
36. Koop H: Metabolic consequences of long-term inhibition of acid secretion by omeprazole. Aliment Pharmacol Ther 1992, 6:399-406.
37. Force RW, Nahata MC: Effect of histamine H2-receptor antagonists on vitamin B12 absorption. Ann Pharmacother 1992, 26:1283-1286.
38. Carmel R, Green R, Jacobsen DW, Rasmussen K, Florea M, Azen C: Serum cobalamin, homocysteine, and methylmalonic acid concentrations in a multiethnic elderly population: ethnic and sex differences in cobalamin and metabolite abnormalities. Am J Clin Nutr 1999, 70:904-910.
39. Lindenbaum J, Rosenberg IH, Wilson PW, Stabler SP, Allen RH: Prevalence of cobalamin deficiency in the Framingham elderly population. Am J Clin Nutr 1994, 60:2-11.
40. Selhub J, Jacques PF, Wilson PW, Rush D, Rosenberg IH: Vitamin status and intake as primary determinants of homocysteinemia in an elderly population. JAMA 1993, 270:2693-2698.
41. Koehler KM, Romero LJ, Stauber PM, Pareo-Tubbeh SL, Liang HC, Baumgartner RN, Garry PJ, Allen RH, Stabler SP: Vitamin supplementation and other variables affecting serum homocysteine and methylmalonic acid concentrations in elderly men and women. J Am Coll Nutr 1996, 15:364-376.
42. Miller JW, Ribaya-Mercado JD, Russell RM, Shepard DC, Morrow FD, Cochary EF, Sadowski JA, Gershoff SN, Selhub J: Effect of vitamin B6-deficiency on fasting plasma homocysteine concentrations. Am J Clin Nutr 1992, 55:1154-1160.
43. Ubbink JB, Vermaak WJ, van der Merwe A, Becker PJ, Delport R, Potgieter HC: Vitamin requirements for the treatment of hyperhomocysteinemia in humans. J Nutr 1994, 124:1927-1933.
44. Nygard O, Vollset SE, Refsum H, Stensvold I, Tverdal A, Nordrehaug JE, Ueland M, Kvale G: Total plasma homocysteine and cardiovascular risk profile: The Hordaland Homocysteine Study. JAMA 1995, 274:1526-1533.
45. Kant AK, Moser-Veillon PB, Reynolds RD: Effect of age on changes in plasma, erythrocyte, and urinary B6 vitamers after an oral vitamin B6 load. Am J Clin Nutr 1988, 48:1284-1290.
46. Rasmussen K, Moller J, Lyngbak M, Pedersen AM, Dybkjaer L: Age-and gender-specific reference intervals for total homo-cysteine and methylmalonic acid in plasma before and after vitamin supplementation. Clin Chem 1996, 42:630-636.
47. Gartler SM, Hornug SK, Motulsky AG: Effect of chronologic age on induction of cystathionine synthase, uroporphyrinogen I synthase, and glucose-6-phosphate dehydrogenase activities in lymphocytes. Proc Natl Acad Sci USA 1981, 78:1916-1919.
48. Matthews FE, Dening T: Prevalence of dementia in institutional care. Lancet 2002, 360:225-226.
49. Keller HH: Malnutrition in institutionalized elderly: how and why? J Am Geriatr Soc 1993, 41:1212-1218.
50. Clarke DM, Wahlqvist ML, Strauss BJG: Undereating and undernutrition in old age: integrating bio-psychosocial aspects. Age and Ageing 1998, 27:527-534.
51. Litchford MD, Wakefield LM: Nutrient intakes and energy expenditures of residents with senile dementia of the Alzheimer's type. J Am Diet Assoc 1987, 87:211-213.