The efficacy of omega-3 fatty acids on cognitive function in aging and dementia: A systematic review

Dementia and Geriatric Cognitive Disorders

Volumn 21, Issue 2, 2006, Pages 88-96

  Issa, Amalia M ^a,b   Mojica, Walter A ^a   Morton, Sally C ^a   Traina, Shana ^a,b,c   Newberry, Sydne J ^a   Hilton, Lara G ^a   Garland, Rena H ^a   MacLean, Catherine H ^a,c,d  

^a RAND CORPORATION   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Alzheimer's disease; Cognitive function in normal aging; Omega 3 fatty acids; Treatment of dementia

Indexed keywords

DOCOSAHEXAENOIC ACID; ICOSAPENTAENOIC ACID; LINOLENIC ACID; OMEGA 3 FATTY ACID;

AGING; CLINICAL TRIAL; COGNITION; COHORT ANALYSIS; COMPARATIVE STUDY; DATA ANALYSIS; DATA BASE; DATA EXTRACTION; DEMENTIA; DIETARY INTAKE; FISH; HUMAN; INCIDENCE; LONGITUDINAL STUDY; META ANALYSIS; METHODOLOGY; OBSERVATIONAL STUDY; PRIORITY JOURNAL; PUBLICATION; REVIEW; RISK FACTOR; SCORING SYSTEM; SYSTEMATIC REVIEW;

AGING; COGNITION DISORDERS; DEMENTIA; FATTY ACIDS, OMEGA-3; HUMANS;

EID: 30844442579     PISSN: 14208008     EISSN: None     Source Type: Journal    
DOI: 10.1159/000090224     Document Type: Review

References (23)

1. U.S. General Accounting Office: Alzheimer's Disease: Estimates of Prevalence in the United States (GAO/HEHS-98-16, 1-45). Washington, U.S. General Accounting Office, 1998.
2. Hebert LE, Beckett LA, Scherr PA, Evans DA: Annual incidence of Alzheimer disease in the United States projected to the years 2000 to 2050. Alz Dis Assoc Disord 2001;4:169-173.
3. Haan MN, Wallace R: Can dementia be prevented? Brain aging in a population-based context. Annu Rev Pub Health 2004;25:1-24.
4. Hashimoto M, Hossain S, Shimada T, Sugioka K, Yamasaki H, Fujii Y, Ishibashi Y, Oka J, Shido O: Docosahexaenoic acid provides protection from impairment of learning ability in Alzheimer's disease model rats. J Neurochem 2002;81:1084-1091.
5. Favrelere S, Stadelmann-Ingrand S, Huguet F, De Javel D, Piriou A, Tallineau C, Durand G: Age-related changes in ethanolamine glycerophospholipid fatty acid levels in rat frontal cortex and hippocampus. Neurobiol Aging 2000;21:653-660.
6. Calon F, Lim GP, Yang F, Morihara T, Teter B, Ubeda O, Rostaing P, Triller A, Salem N Jr, Ashe KH, Frautschy SA, Cole GM: Docosahexaenoic acid protects from dendritic pathology in an Alzheimer's disease mouse model. Neuron 2004;43:633-664.
7. Cooper JL: Dietary lipids in the aetiology of Alzheimer's disease: implications for therapy. Drugs Aging 2003;20:399-418.
8. Friedland R: Fish consumption and the risk of Alzheimer disease: is it time to make dietary recommendations? Arch Neurol 2003;60:923-924.
9. http://qualitycounts.com/fpfattyacids.html. Accessed February 10, 2005.
10. http://www.discount-vitamins-herbs.net/health-news27.htm. Accessed February 10, 2005.
11. Weil M, Bressler J, Parsons P, Bolla K, Glass T, Schwartz B: Blood mercury levels and neurobehavioral function. JAMA 2005;293:1875-1882.
12. MacLean CH, Issa AM, Newberry SJ, Mojica WA, Morton SC, Garland RH, Hilton LG, Traina SB, Shekelle PG: Effects of Omega-3 Fatty Acids on Cognitive Function with Aging, Dementia, and Neurological Diseases. Evidence Report/Technology Assessment No. 114 (Prepared by the Southern California Evidence-Based Practice Center, under contract No. 290-02-0003). Publication No. 05-E011-2. Rockville, Agency for Healthcare Research and Quality, February 2005.
13. Jadad AR, Moore RA, Carroll D, Jenkinson C, Reynolds DJ, Gavaghan DJ, McQuay HJ: Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control Clin Trials 1996;17:1-12.
14. Downs S, Black N: The feasibility of creating a checklist for the assessment of the methodological quality both of randomised and non-randomised studies of health care interventions. J Epidemiol Community Health 1998;52:377-384.
15. Saunders L, Soomro G, Buckingham J, Jamtvedt G, Raina P: Assessing the methodological quality of nonrandomized intervention studies. West J Nurs Res 2003;25:223-237.
16. Kalmijn S, Feskens EJ, Launer LJ, Kromhout D: Polyunsaturated fatty acids, antioxidants, and cognitive function in very old men. Am J Epidemiol 1997;145:33-41.
17. Barberger-Gateau P, Letenneur L, Deschamps V, Peres K, Dartigues JF, Renaud S: Fish, meat, and risk of dementia: cohort study. BMJ 2002;325:932-933.
18. Morris MC, Evans DA, Bienias JL, Tangney CC, Bennett DA, Wilson RS, Aggarwal N, Schneider J: Consumption of fish and n-3 fatty acids and risk of incident Alzheimer disease. Arch Neurol 2003;60:940-946.
19. Kalmijn S, Launer LJ, Ott A, Witteman JC, Hofman A, Breteler MM: Dietary fat intake and the risk of incident dementia in the Rotterdam study. Ann Neurol 1997;42:776-782.
20. Terano T, Fujishiro S, Ban T, Yamamoto K, Tanaka T, Noguchi Y, Tamura Y, Yazawa K, Hirayama T: Docosahexaenoic acid supplementation improves the moderately severe dementia from thrombotic cerebrovascular diseases. Lipids 1999;34(suppl):S345-S346.
21. Willet W: Overview of nutritional epidemiology; in Willet W (ed): Nutritional Epidemiology, ed 2. New York, Oxford University Press, 1998, pp 3-17.
22. Grimes DA, Schulz KF: Cohort studies: marching towards outcomes. Lancet 2002;359:341-345.
23. Grimes DA, Schulz KF: Bias and causal associations in observational research. Lancet 2002;359:248-252.