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Volumn 17, Issue 1, 2006, Pages 85-88

Genetics and molecular biology: Macrophage ACAT depletion - Mechanisms of atherogenesis

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL ACYLTRANSFERASE; CHOLESTEROL ACYLTRANSFERASE INHIBITOR;

EID: 30744466140     PISSN: 09579672     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.mol.0000203192.45649.ba     Document Type: Editorial
Times cited : (9)

References (11)
  • 2
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    • Potential role of acyl-coenzyme A:cholesterol transferase (ACAT) inhibitors as hypolipidemic and antiatherosclerosis drugs
    • Leon C, Hill JS, Wasan KM. Potential role of acyl-coenzyme A:cholesterol transferase (ACAT) inhibitors as hypolipidemic and antiatherosclerosis drugs. Pharm Res 2005; 22:1578-1588.
    • (2005) Pharm Res , vol.22 , pp. 1578-1588
    • Leon, C.1    Hill, J.S.2    Wasan, K.M.3
  • 3
    • 0034023061 scopus 로고    scopus 로고
    • Massive xanthomatosis and altered composition of atherosclerotic lesions in hyperlipidemic mice lacking acyl CoA:cholesterol acyltransferase 1
    • Accad M, Smith SJ, Newland DL, et al. Massive xanthomatosis and altered composition of atherosclerotic lesions in hyperlipidemic mice lacking acyl CoA:cholesterol acyltransferase 1. J Clin Invest 2000; 105:711-719.
    • (2000) J Clin Invest , vol.105 , pp. 711-719
    • Accad, M.1    Smith, S.J.2    Newland, D.L.3
  • 4
    • 0035139793 scopus 로고    scopus 로고
    • Increased atherosclerosis in LDL receptor-null mice lacking ACAT1 in macrophages
    • Fazio S, Major AS, Swift LL, et al. Increased atherosclerosis in LDL receptor-null mice lacking ACAT1 in macrophages. J Clin Invest 2001; 107:163-171.
    • (2001) J Clin Invest , vol.107 , pp. 163-171
    • Fazio, S.1    Major, A.S.2    Swift, L.L.3
  • 5
    • 0028964742 scopus 로고
    • Cell toxicity induced by inhibition of acyl coenzyme A:cholesterol acyltransferase and accumulation of unesterified cholesterol
    • Warner GJ, Stoudt G, Bamberger M, et al. Cell toxicity induced by inhibition of acyl coenzyme A:cholesterol acyltransferase and accumulation of unesterified cholesterol. J Biol Chem 1995; 270:5772-5778.
    • (1995) J Biol Chem , vol.270 , pp. 5772-5778
    • Warner, G.J.1    Stoudt, G.2    Bamberger, M.3
  • 6
    • 18444396937 scopus 로고    scopus 로고
    • Reduced ABCA1-mediated cholesterol efflux and accelerated atherosclerosis in apolipoprotein E-deficient mice lacking macrophage-derived ACAT1
    • Su YR, Dove DE, Major AS, et al. Reduced ABCA1-mediated cholesterol efflux and accelerated atherosclerosis in apolipoprotein E-deficient mice lacking macrophage-derived ACAT1. Circulation 2005; 111:2373-2381.
    • (2005) Circulation , vol.111 , pp. 2373-2381
    • Su, Y.R.1    Dove, D.E.2    Major, A.S.3
  • 7
    • 11144227415 scopus 로고    scopus 로고
    • ACAT1 deficiency disrupts cholesterol efflux and alters cellular morphology in macrophages
    • Dove DE, Su YR, Zhang W, et al. ACAT1 deficiency disrupts cholesterol efflux and alters cellular morphology in macrophages. Arterioscler Thromb Vasc Biol 2005; 25:128-134.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 128-134
    • Dove, D.E.1    Su, Y.R.2    Zhang, W.3
  • 8
    • 30744475957 scopus 로고    scopus 로고
    • ACAT1 deficiency increases cholesterol synthesis in mouse peritoneal macrophages
    • Sept 3. PMID: 16144700 [Epub ahead of print]
    • Dove DE, Su YR, Swift LL, et al. ACAT1 deficiency increases cholesterol synthesis in mouse peritoneal macrophages. Atherosclerosis, 2005; Sept 3. PMID: 16144700 [Epub ahead of print].
    • (2005) Atherosclerosis
    • Dove, D.E.1    Su, Y.R.2    Swift, L.L.3
  • 9
    • 24344496119 scopus 로고    scopus 로고
    • Acyl-coenzyme A:cholesterol acyltransferase promotes oxidized LDL/oxysterol-induced apoptosis in macrophages
    • Freeman NE, Rusinol AE, Linton M, et al. Acyl-coenzyme A:cholesterol acyltransferase promotes oxidized LDL/oxysterol-induced apoptosis in macrophages. J Lipid Res 2005; 46:1933-1943.
    • (2005) J Lipid Res , vol.46 , pp. 1933-1943
    • Freeman, N.E.1    Rusinol, A.E.2    Linton, M.3
  • 10
    • 13844271997 scopus 로고    scopus 로고
    • Systemic acyl-CoA:cholesterol acyltransferase inhibition reduces inflammation and improves vascular function in hypercholesterolemia
    • Kharbanda RK, Wallace S, Walton B, et al. Systemic acyl-CoA:cholesterol acyltransferase inhibition reduces inflammation and improves vascular function in hypercholesterolemia. Circulation 2005; 111:804-807.
    • (2005) Circulation , vol.111 , pp. 804-807
    • Kharbanda, R.K.1    Wallace, S.2    Walton, B.3
  • 11
    • 11144248038 scopus 로고    scopus 로고
    • Acyl-coenzyme a (CoA):cholesterol acyltransferase inhibition in rat and human aortic smooth muscle cells is nontoxic and retards foam cell formation
    • Rong JX, Kusunoki J, Oelkers P, et al. Acyl-coenzyme A (CoA):cholesterol acyltransferase inhibition in rat and human aortic smooth muscle cells is nontoxic and retards foam cell formation. Arterioscler Thromb Vasc Biol 2005; 25:122-127.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 122-127
    • Rong, J.X.1    Kusunoki, J.2    Oelkers, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.