Cytotoxic activity of 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide is underlain by DNA interchain cross-linking

Cellular and Molecular Life Sciences

Volumn 63, Issue 2, 2006, Pages 229-234

  Moshnikova, A B ^a   Afanasyev, V N ^b   Proussakova, O V ^a,c   Chernyshov, S ^a   Gogvadze, V ^a,d   Beletsky, I P ^a,c  

^a INSTITUTE OF THEORETICAL AND EXPERIMENTAL BIOPHYSICS   (Russian Federation)

^b INSTITUTE OF CELL BIOPHYSICS   (Russian Federation)

^c I M SECHENOV FIRST MOSCOW STATE MEDICAL UNIVERSITY   (Russian Federation)

^d KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Antitumor activity; Apoptosis; Cell cycle; Cross linker; Necrosis

Indexed keywords

1 (3 DIMETHYLAMINOPROPYL) 3 ETHYLCARBODIIMIDE;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ARTICLE; CELL CULTURE; CELL CYCLE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL DEATH; CELL KINETICS; CONTROLLED STUDY; DNA CROSS LINKING; DRUG CYTOTOXICITY; HUMAN; HUMAN CELL; LIFESPAN; MALE; MOUSE; NONHUMAN;

ANIMALS; CELL DEATH; CELL LINE; CERCOPITHECUS AETHIOPS; CROSS-LINKING REAGENTS; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYTOKINESIS; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHYLDIMETHYLAMINOPROPYL CARBODIIMIDE; HUMANS; MALE; MICE; MICE, INBRED DBA;

ANIMALIA;

EID: 30744457817     PISSN: 1420682X     EISSN: 15691632     Source Type: Journal    
DOI: 10.1007/s00018-005-5383-x     Document Type: Article

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