Systemic correction of a fatty acid oxidation defect by intramuscular injection of a recombinant adeno-associated virus vector

Human Gene Therapy

Volumn 17, Issue 1, 2006, Pages 71-80

  Conlon, Thomas J ^a   Walter, Glenn ^b   Owen, Renius ^a   Cossette, Travis ^a   Erger, Kirsten ^a   Gutierrez, Greg ^b   Goetzman, Eric ^c   Matern, Dietrich ^d   Vockley, Jerry ^c   Flotte, Terence R ^a,b  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

^c CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^d MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACYL COENZYME A DEHYDROGENASE; BUTYRYL COENZYME A DEHYDROGENASE; CARNITINE; FATTY ACID; GENE PRODUCT; PARVOVIRUS VECTOR; TRICARBOXYLIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL LINE; CITRIC ACID CYCLE; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; FATTY ACID OXIDATION; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VIVO STUDY; LIVER; MITOCHONDRION; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SKELETAL MUSCLE; VIRAL GENE THERAPY; VIRUS CAPSID; VIRUS RECOMBINANT; VIRUS STRAIN;

ANIMALS; BUTYRYL-COA DEHYDROGENASE; CARNITINE; CELL LINE; DEPENDOVIRUS; DNA, RECOMBINANT; FATTY ACIDS; FEMALE; FIBROBLASTS; GENE THERAPY; GENETIC VECTORS; HUMANS; INJECTIONS, INTRAMUSCULAR; LIPID METABOLISM, INBORN ERRORS; MASS SPECTROMETRY; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MITOCHONDRIA; MUSCLES; OXIDATION-REDUCTION; REPRODUCIBILITY OF RESULTS; TRANSDUCTION, GENETIC;

ADENO-ASSOCIATED VIRUS; ANIMALIA; MIRIDAE; PARVOVIRUS;

EID: 30744432678     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/hum.2006.17.71     Document Type: Article

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