Is the insulin resistance syndrome the price to be paid to achieve body weight stability?

International Journal of Obesity

Volumn 29, Issue 10, 2005, Pages 1295-1298

  Tremblay, A ^a   Boule N ^a   Doucet, E ^b   Woods, S C ^c  

^a UNIVERSITÉ LAVAL   (Canada)

^b UNIVERSITY OF OTTAWA   (Canada)

^c UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

Appetite control; Energy expenditure; Insulin

Indexed keywords

ARTICLE; BODY WEIGHT; DIABETES MELLITUS; DIET; ENERGY BALANCE; ENERGY EXPENDITURE; HUMAN; HYPERINSULINEMIA; INSULIN BLOOD LEVEL; ISCHEMIC HEART DISEASE; MEDICAL RESEARCH; METABOLIC SYNDROME X; PHYSICAL ACTIVITY; PRIORITY JOURNAL;

ENERGY METABOLISM; HUMANS; INSULIN RESISTANCE; METABOLIC SYNDROME X; WEIGHT LOSS;

EID: 30544453973     PISSN: 03070565     EISSN: 14765497     Source Type: Journal    
DOI: 10.1038/sj.ijo.0803019     Document Type: Article

References (27)

1. Reaven GM. Role of insulin resistance in human disease. Diabetes 1988; 37: 1495-1507.
2. Després JP, Moorjani S, Lupien PJ, Tremblay A, Nadeau A, Bouchard C. Regional distribution of body fat, plasma lipoproteins and cardiovascular disease. Arteriosclerosis 1990; 10: 497-511.
3. Woods SC, Lotter EC, McKay ID, Porte DJ. Chronic intracerebroventricular infusion of insulin reduces food intake and body weight of baboons. Nat Med 1979; 282: 503-505.
4. Woods SC, Porte DJ. Insulin and the set-point regulation of body weight. In: Novin D, Bray GA, Wyrwichka W (eds). Hunger: Basic Mechanisms and Clinical Implications. Raven Press: New York; 1976. pp 273-280.
5. Porte D, Woods SC. Regulation of food intake and body weight by insulin. Diabetologia 1981; 20: 274-280.
6. Woods SC. Insulin and the brain: a mutual dependency. Prog Psychobiol Physiol Psychol 1995; 16: 53-81.
7. Woods SC, Seeley RJ, Porte DJ, Schwartz MW. Signals that regulate food intake and energy homeostasis. Science 1998; 280: 1378-1383.
8. Porte DJ, Seeley RJ, Woods SC, Baskin DG, Figlewiez DP, Schwartz MW. Obesity, diabetes and the CNS. Diabetologia 1998; 41: 863-881.
9. Rowe JW, Young JB, Minaker KL, Steven AL, Pallotta J, Lansberg L. Effect of insulin and glucose infusions on sympathetic nervous system activity in normal man. Diabetes 1981; 30: 219-225.
10. Berne C, Fagius J, Pollare T, Hemjdahl P. The sympathetic response to euglycemic hyperinsulinemia. Diabetologia 1992; 35: 873-879.
11. Vollenweider P, Tappy L, Randin D, Schneiter P, Jequier E, Nicod P, Scherrer U. Differential effects of hyperinsulinemia and carbohydrate metabolism on sympathetic nerve activity and muscle blood flow in humans. J Clin Invest 1993; 92: 147-154.
12. Schwartz MW, Sipols AJ, Marks JL, Sanacora G, White JD, Scheurink A, Kahn SE, Baskin DG, Woods SC, Figlewicz DP, Porte D. Inhibition of hypothalamic neuropeptide Y gene expression by insulin. Endocrinology 1992; 130: 3608-3616.
13. Benoit SC, Air EE, Coolen LM, Strauss R, Jackman A, Clegg DJ, Seeley RJ, Woods SC. The catabolic action of insulin in the brain is mediated by melanocortins. J Neurosci 2002; 22: 9048-9052.
14. Doucet E, St-Pierre S, Aimeras N, Mauriege P, Despres JP, Richard D, Bouchard C, Tremblay A. Fasting insulin levels influence plasma leptin levels independently from the contribution of adiposity: evidence from both a cross-sectional and an intervention study. J Clin Endocrinol Metabol 2000; 85: 4231-4237.
15. Air EE, Benoit SC, Clegg DJ, Seeley RJ, Woods SC. Insulin and leptin combine additively to reduce food intake and body weight in rats. Endocrinology 2002; 143: 2449-2452.
16. Schwartz MW, Peskind E, Raskind M, Boyko EJ, Porte Jr D. Cerebrospinal fluid leptin levels: relationship to plasma levels and to adiposity in humans. Nat Med 1996; 2: 589-593.
17. Seeley RJ, Yagaloff K, Fisher S, Burn P, Thiele T, van Dijk G, Baskin D, Schwartz M. Melanocortin receptors in leptin effects. Nature 1997; 390: 349.
18. Boden G, Chen X, Kolaczynski JW, Polansky M. Effects of prolonged hyperinsulinemia on serum leptin in normal human subjects. J Clin Invest 1997; 100: 1107-1113.
19. Saad MF, Khan A, Sharma A, Michael R, Riad-Gabriel MG, Boyadjian R, Jinagouda SD, Steil GM, Kamdar V. Physiological insulinemia acutely modulates plasma leptin. Diabetes 1998; 47: 544-549.
20. Tremblay A, Nadeau A, Després J-P, Bouchard C. Hyperinsulinemia and regulation of energy balance. Am J Clin Nutr 1995; 61: 827-830.
21. Swinburn B, Nyomba BL, Saad MF, Zurlo F, Raz I, Knowler WC, Lillioja S, Bogardus C, Ravussin E. Insulin resistance associated with low rates of weight gain in Pima Indians. J Clin Invest 1991; 88: 168-173.
22. Schwartz MW, Boyko EJ, Kahn SE, Ravussin E, Bogardus C. Reduced insulin secretion: an independent predictor of body weight gain. J Clin Endocrinol Metabol 1995; 80: 1571-1576.
23. Tremblay A, Doucet E. Obesity: a disease or a biological adaptation? Obes Rev 2000; 1: 27-35.
24. Doucet E, St-Pierre S, Alméras N, Després J-P, Bouchard C, Tremblay A. Evidence for the existence of adaptive thermogenesis during weight loss. Br J Nutr 2001; 85: 715-723.
25. Ravussin E, Lillioja S, Knowler WC, Christin L, Freymond D, Abbott WGH, Boyce V, Howard BV, Bogardus C. Reduced rate of energy expenditure as a risk factor for body-weight gain. N Engl J Med 1988; 318: 467-472.
26. Pasman WJ, Saris WH, Westerterp-Plantenga MS. Predictors of weight maintenance. Obes Res 1999; 7: 43-50.
27. Eckel RH. Insulin resistance: an adaptation for weight maintenance. Lancet 1992; 340: 1452-1453.