Antagonistic effects of IL-4 and interferon-gamma (IFN-γ) on inducible nitric oxide synthase expression in bovine macrophages exposed to Gram- positive bacteria

Clinical and Experimental Immunology

Volumn 109, Issue 3, 1997, Pages 431-438

  Jungi, T W ^a,b   Brcic, M ^a   Sager, H ^a   Dobbelaere, D A E ^a   Furger, A ^a   Roditi, I ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b Institute of Veterinary Anatomy   (Switzerland)

Author keywords

Cattle; IL 4; Inducible nitric oxide synthase; Interferon gamma; Macrophages; NO

Indexed keywords

ALPHA INTERFERON; GAMMA INTERFERON; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 4; NEUTRALIZING ANTIBODY; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ARTICLE; COW; GENE EXPRESSION REGULATION; GRAM POSITIVE BACTERIUM; HELPER CELL; IMMUNOASSAY; LISTERIA MONOCYTOGENES; MACROPHAGE; MACROPHAGE ACTIVATION; MACROPHAGE FUNCTION; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; SALMONELLA DUBLIN; SPECIES DIFFERENCE;

EID: 0030850289     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.1997.4891384.x     Document Type: Article

References (40)

1. Street NE, Mosmann TR. Functional diversity of T lymphocytes due to secretion of different cytokine patterns. FASEB J 1991; 5:171-7.
2. + T-cell clones obtained from cattle chronically infected with Fasciola hepatica and specific for adult worm antigen express both unrestricted and Th2 cytokine profiles. Infect Immun 1994; 62:818-27.
3. Brown WC, Davis WC, Tuo W. Human interleukin-12 upregulates proliferation and interferon-gamma production by parasite antigen-stimulated Th cell clones and gamma/delta T cells of cattle. Ann NY Acad Sci 1996; 795:321-4.
4. Adams DO, Hamilton TA. The cell biology of macrophage activation. Annu Rev Immunol 1984; 2:283-318.
5. Nathan CF, Prendergast TJ, Wiebe ME et al. Activation of human macrophages. Comparison of other cytokines with interferon-gamma. J Exp Med 1984; 160:600-5.
6. Nishioka Y, Sone S, Orino E, Nii A, Ogura T, Down-regulation by interleukin 4 of activation of human alveolar macrophages to the tumoricidal state. Cancer Res 1991; 51:5526-31.
7. Sone S, Yanagawa H, Nishioka Y et al. Interleukin-4 as a potent down-regulator tor human alveolar macrophages capable of producing tumour necrosis factor-alpha and interleukin-1. Eur Resp J 1992; 5:174-81.
8. Moutabarrik A, Takahara S, Namiki M et al. Contrasting effects of interferon-gamma and interleukin-4 on neopterin generation from human adherent monocytes. Lymphokine Cytokine Res 1992; 11:327-30.
9. Kumaratilake LM, Ferrante A. IL-4 inhibits macrophage-mediated killing of Plasmodium falciparum in vitro. A possible parasite-immune evasion mechanism. J Immunol 1992; 149:194-9.
10. Gautam S, Tebo JM, Hamilton TA. IL-4 suppresses cytokine gene expression induced by IFN-gamma and/or IL-2 in murine peritoneal macrophages. J Immunol 1992; 148:1725-30.
11. Bogdan C, Nathan C. Modulation of macrophage function by transforming growth factor beta, interleukin-4, and interleukin-10. Ann NY Acad Sci 1993; 685:713-39.
12. Stein M, Keshav S, Harris N, Gordon S. Interleukin 4 potently enhances murine macrophage mannose receptor activity: a marker of alternative immunologic macrophage activation. J Exp Med 1992; 176:287-92.
13. van Hal PT, Hopstaken Broos JP, Wijkhuijs JM, te Velde AA, Figdor CG, Hoogsteden HC. Regulation of aminopeptidase-N (CD13) and Fe epsilon RIIb (CD23) expression by IL-4 depends on the stage of maturation of monocytes/macrophages. J Immunol 1992; 149:1395-401.
14. McBride WH, Economou JS, Nayersina R, Comora S, Essner R. Influences of interleukins 2 and 4 on tumor necrosis factor production by murine mononuclear phagocytes. Cancer Res 1990; 50:2949-52.
15. Ruppert J, Friedrichs D, Xu H, Peters JH. IL-4 decreases the expression of the monocyte differentiation marker CD14, paralleled by an increasing accessory potency. Immunobiology 1991; 182:449-64.
16. Lauener RP, Goyert SM, Geha RS, Vercelli D. Interleukin 4 down-regulates the expression of CD14 in normal human monocytes. Eur J Immunol 1990; 20:2375-81.
17. Ding AH, Nathan CF, Stuehr DJ. Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production. J Immunol 1988; 141:2407-12.
18. Adler H, Peterhans E, Nicolet J, Jungi TW. Inducible L-arginine-dependent nitric oxide synthase activity in bovine bone marrow-derived macrophages. Biochem Biophys Res Commun 1994; 198:510-5.
19. Adler H, Frech B, Thöny M, Pfister H, Peterhans E, Jungi TW. Inducible nitric oxide synthase in cattle. Differential cytokine regulation of nitric oxide synthase in bovine and murine macrophages. J Immunol 1995; 154:4710-8.
20. Billman-Jacobe H, Carrigan M, Cockram F, Corner LA, Gill U, Hill JF, Milner AR, Wood PR. A comparison of the interferon gamma assay with the absorbed ELISA for the diagnosis of Johne's disease in cattle. Austr Vet J 1992; 69:25-28.
21. Rothel JS, Jones SL, Corner LA, Cox JC, Wood PR. A sandwich enzyme immunoassy for bovine interferon-gamma and its use for detection of tuberculosis in cattle. Austr Vet J 1990; 67:134-7.
22. Heussler VT, Eichhorn M, Dobbelaere DAE. Cloning of a full-length cDNA encoding bovine interleukin 4 by the polymerase chain reaction. Gene 1992; 114:273-8.
23. Bayne RAL, Kilbride EA, Lainson FA, Tetley L, Barry JD. A major surface antigen of procyclic stage Trypanosoma congolense. Mol Biochem Parasitol 1943; 61:295-310.
24. Brun R, Schoenenberger M. Cultivation and in vitro cloning of procyclic culture forms of Trypanosoma brucei in a semi-defined medium. Acta Tropica 1979; 36:289-92.
25. Julius MH, Simpson E, Herzenberg LA. A rapid method for the isolation of functional thymus-derived murine lymphocytes. Eur J Immunol 1973; 3:645-9.
26. Jungi TW, Thöny M, Brcic M, Adler B, Pauli U, Peterhans E. Induction of nitric oxide synthase in bovine mononuclear phagocytes is differentiation stage-dependent. Immunobiology 1996; 195:385-400.
27. Nakagawa Tosa N, Morimatsu M, Kawasaki M, Nakatsuji H, Syuto B, Saito M. Stimulation of haptoglobin synthesis by interleukin-6 and tumor necrosis factor, but not by interleukin-1, in bovine primary cultured hepatocytes. J Vet Med Sci 1995; 57:219-23.
28. Pighetti GM, Sordillo LM. Enhanced antigen-specific responses in bovine mammary glands following administration of interleukin-2. J Dairy Sci 1995; 78:528-37.
29. Hill FW, Klein WR, Hoyer MJ et al. Antitumor effect of locally injected low doses of recombinant human interleukin-2 in bovine vulval papilloma and carcinoma. Vet Immunol Immunopathol 1994; 41:19-29.
30. Alpizar E, Spicer LJ. Effects of interleukin-6 on proliferation and follicle-stimulating hormone-induced estradiol production by bovine granulosa cells in vitro: dependence on size of follicle. Biol Reprod 1994; 50:38-43.
31. Chitko McKown CG, Ruef BJ, Rice Ficht AC, Brown WC. Interleukin-10 downregulates proliferation and expression of interleukin-2 receptor p55 chain and interferon-gamma, but not interleukin-2 or interleukin-4, by parasite-specific helper T cell clones obtained from cattle chronically infected with Babesia bovis or Fasciola hepatica. J Interferon Cytokine Res 1995; 15:915-22.
32. Chapman CG, Clinkenbeard HE, Parker KE, Spackman VM, Dobbelaere DAE, Robinson JH, Browne MJ. Structure/function analysis of interleukin 4: interspecies comparison and site-directed mutagenesis. Biochem Soc Trans 1994; 22:234S.
33. Schneemann M, Schoedon G, Hofer S, Blau N, Guerrero L, Schaffner A. Nitric oxide synthase is not a constituent of the antimicrobial armature of human mononuclear phagocytes. J Infect Dis 1993; 167:1358-63.
34. Adler H, Adler B, Peveri P, Werner ER, Wachter H, Peterhans E, Jungi TW. Differential regulation of inducible nitric oxide synthase production in bovine and caprine macrophages. J Infect Dis 1996; 173:971-8.
35. Adler B, Adler H, Jungi TW, Peterhans E. Interferon-alpha primes macrophages for lipopolysaccharide-induced apoptosis. Biochem Biophys Res Commun 1995; 215:921-7.
36. Goff WL, Johnson WC, Wyatt CR, Cluff CW. Assessment of bovine mononuclear phagocytes and neutrophils for induced L-arginine-dependent-nitric oxide production. Vet Immunol Immunopathol 1996; 55:45-62.
37. Mason GL, Yang Z, Olchowy TWJ, Jian Z, Bochsler PN. Nitric oxide production and expression of inducible nitric oxide synthase by bovine alveolar macrophages. Vet Immunol Immunopathol 1996; 53:15-27.
38. 2- production as a sensitive and rapid assay for the quantilation of murine IFN-gamma. J Immunol Methods 1991; 139:107-14.
39. Wright SD. CD14 and innate recognition of bacteria. J Immunol 1995; 155:6-8.
40. Trinchieri G. Role of interleukin-12 in human Th1 response. Chem Immunol 1996; 63:14-29.