메뉴 건너뛰기




Volumn 130, Issue 1, 2006, Pages 33-38

Promoter hypermethylation of the p16 gene and loss of its protein expression is correlated with tumor progression in extrahepatic bile duct carcinomas

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P16;

EID: 30444450833     PISSN: 00039985     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (17)

References (41)
  • 1
    • 0028860304 scopus 로고
    • Liver, gallbladder, extrahepatic bile duct, and pancreas
    • Carriaga MT, Henson DE. Liver, gallbladder, extrahepatic bile duct, and pancreas. Cancer. 1995;75:171-190.
    • (1995) Cancer , vol.75 , pp. 171-190
    • Carriaga, M.T.1    Henson, D.E.2
  • 2
    • 0346769307 scopus 로고    scopus 로고
    • Ministry of Health and Welfare, Korea. Survey report on cancer patients in 1992. Available at: http://www.mohw.go.kr/english/index.html, 1996. Accessed November 20, 2004.
    • (1996) Survey Report on Cancer Patients in 1992
  • 3
    • 0033965567 scopus 로고    scopus 로고
    • High frequency of K-ras mutations in biliary tract carcinomas of cases with a long common channel in the papilla of Vater
    • Hidaka E, Yanagisawa A, Seki M, Setoguchi T, Kato Y. High frequency of K-ras mutations in biliary tract carcinomas of cases with a long common channel in the papilla of Vater. Cancer Res. 2000;60:522-524.
    • (2000) Cancer Res , vol.60 , pp. 522-524
    • Hidaka, E.1    Yanagisawa, A.2    Seki, M.3    Setoguchi, T.4    Kato, Y.5
  • 4
    • 0028997957 scopus 로고
    • Ki-ras mutations as a prognostic factor in extrahepatic bile system cancer, PANK-ras project investigators
    • Malats N, Porta M, Pinol JL, Corominas JM, Rifa J, Real FX. Ki-ras mutations as a prognostic factor in extrahepatic bile system cancer, PANK-ras project investigators. J Clin Oncol. 1995;13:1679-1686.
    • (1995) J Clin Oncol , vol.13 , pp. 1679-1686
    • Malats, N.1    Porta, M.2    Pinol, J.L.3    Corominas, J.M.4    Rifa, J.5    Real, F.X.6
  • 5
    • 0036793788 scopus 로고    scopus 로고
    • K-ras mutation, p53 overexpression, and microsatellite instability in biliary tract cancers: A population-based study in China
    • Rashid A, Ueki T, Gao YT, et al. K-ras mutation, p53 overexpression, and microsatellite instability in biliary tract cancers: a population-based study in China. Clin Cancer Res. 2002;8:3156-3163.
    • (2002) Clin Cancer Res , vol.8 , pp. 3156-3163
    • Rashid, A.1    Ueki, T.2    Gao, Y.T.3
  • 6
    • 0034107937 scopus 로고    scopus 로고
    • Aberrations of the K-ras, p53, and APC genes in extrahepatic bile duct cancer
    • Suto T, Habano W, Sugai T, et al. Aberrations of the K-ras, p53, and APC genes in extrahepatic bile duct cancer. J Surg Oncol. 2000;73:158-163.
    • (2000) J Surg Oncol , vol.73 , pp. 158-163
    • Suto, T.1    Habano, W.2    Sugai, T.3
  • 7
    • 0031852049 scopus 로고    scopus 로고
    • Diagnosis and prognostic value of incidence of K-ras codon 12 mutation in resected distal bile duct carcinoma
    • Rijken AM, van Gulik TM, Polak MM, Sturm PD, Gouma DJ, Offerhaus GJ. Diagnosis and prognostic value of incidence of K-ras codon 12 mutation in resected distal bile duct carcinoma. J Surg Oncol. 1998;68:187-192.
    • (1998) J Surg Oncol , vol.68 , pp. 187-192
    • Rijken, A.M.1    Van Gulik, T.M.2    Polak, M.M.3    Sturm, P.D.4    Gouma, D.J.5    Offerhaus, G.J.6
  • 8
    • 0035870269 scopus 로고    scopus 로고
    • B-catenin mutations in biliary tract cancers: A population-based study in China
    • Rashid A, Gao YT, Bhakta S, et al. B-catenin mutations in biliary tract cancers: a population-based study in China. Cancer Res. 2001;61:3406-3409.
    • (2001) Cancer Res , vol.61 , pp. 3406-3409
    • Rashid, A.1    Gao, Y.T.2    Bhakta, S.3
  • 9
    • 0035312199 scopus 로고    scopus 로고
    • Differing rates of loss of Dpc4 expression and p53 overexpression among carcinomas of the proximal and distal bile ducts: Evidence for a biological distinction
    • Argani P, Shaukat A, Kaushal M, et al. Differing rates of loss of Dpc4 expression and p53 overexpression among carcinomas of the proximal and distal bile ducts: evidence for a biological distinction. Cancer. 2001;91:1332-1341.
    • (2001) Cancer , vol.91 , pp. 1332-1341
    • Argani, P.1    Shaukat, A.2    Kaushal, M.3
  • 10
    • 0033150246 scopus 로고    scopus 로고
    • Chromosome 9p21 loss and p16 inactivation in primary sclerosing cholangitis-associated cholangiocarcinoma
    • Ahrendt SA, Eisenberger CF, Yip L, et al. Chromosome 9p21 loss and p16 inactivation in primary sclerosing cholangitis-associated cholangiocarcinoma. J Surg Res. 1999;84:88-93.
    • (1999) J Surg Res , vol.84 , pp. 88-93
    • Ahrendt, S.A.1    Eisenberger, C.F.2    Yip, L.3
  • 11
    • 1842428729 scopus 로고    scopus 로고
    • Alterations of p16 and prognosis in biliary tact cancers from a population-based study in china
    • Ueki T, Hsing AW, Gao YT, et al. Alterations of p16 and prognosis in biliary tact cancers from a population-based study in china. Clin Cancer Res. 2004;10:1717-1725.
    • (2004) Clin Cancer Res , vol.10 , pp. 1717-1725
    • Ueki, T.1    Hsing, A.W.2    Gao, Y.T.3
  • 13
    • 0036771842 scopus 로고    scopus 로고
    • INK4a promoter mutations are frequent in primary sclerosing cholangitis (PSC) and PSC associated cholangiocarcinoma
    • INK4a promoter mutations are frequent in primary sclerosing cholangitis (PSC) and PSC associated cholangiocarcinoma. Gastroenterology. 2002;123:1090-1098.
    • (2002) Gastroenterology , vol.123 , pp. 1090-1098
    • Taniai, M.1    Higuchi, H.2    Burgart, L.J.3    Gores, G.J.4
  • 14
    • 0034125594 scopus 로고    scopus 로고
    • Expression and clinical significance of the G1-S modulators in carcinoma of the extrahepatic bile duct
    • Ito Y, Takeda T, Sakon M, Monden M, Tsujimoto M, Matsuura N. Expression and clinical significance of the G1-S modulators in carcinoma of the extrahepatic bile duct. Anticancer Res. 2000;20:337-344.
    • (2000) Anticancer Res , vol.20 , pp. 337-344
    • Ito, Y.1    Takeda, T.2    Sakon, M.3    Monden, M.4    Tsujimoto, M.5    Matsuura, N.6
  • 15
    • 0036518697 scopus 로고    scopus 로고
    • Down-regulated pi 6 expression predicts poor prognosis in patients with extrahepatic biliary tract carcinomas
    • Ichikawa K, Imura J, Kawamata H, Takeda J, Fujimori T. Down-regulated pi 6 expression predicts poor prognosis in patients with extrahepatic biliary tract carcinomas. Int J Oncol. 2002;20:453-461.
    • (2002) Int J Oncol , vol.20 , pp. 453-461
    • Ichikawa, K.1    Imura, J.2    Kawamata, H.3    Takeda, J.4    Fujimori, T.5
  • 16
    • 0033773706 scopus 로고    scopus 로고
    • Alterations of retinoblastoma protein and p16INK4 protein expression in extrahepatic bile duct carcinomas
    • Cui X, Hui AM, Li X, et al. Alterations of retinoblastoma protein and p16INK4 protein expression in extrahepatic bile duct carcinomas. Hepatogastroenterology. 2000;47:1216-1220.
    • (2000) Hepatogastroenterology , vol.47 , pp. 1216-1220
    • Cui, X.1    Hui, A.M.2    Li, X.3
  • 17
    • 0038327718 scopus 로고    scopus 로고
    • Promoter methylation of INK43/ARF as detected in bile: Significance for the differential diagnosis in biliary disease
    • Klump B, Hsieh CJ, Dette S, Holzmann K, et al. Promoter methylation of INK43/ARF as detected in bile: significance for the differential diagnosis in biliary disease. Clin Cancer Res. 2003;9:1773-1778.
    • (2003) Clin Cancer Res , vol.9 , pp. 1773-1778
    • Klump, B.1    Hsieh, C.J.2    Dette, S.3    Holzmann, K.4
  • 18
    • 5044235077 scopus 로고    scopus 로고
    • Promoter hypermethylation of DAP-kinase is associated with poor survival in primary biliary tract carcinoma patients
    • Tozawa T, Tamura G, Honda T, et al. Promoter hypermethylation of DAP-kinase is associated with poor survival in primary biliary tract carcinoma patients. Cancer Sci. 2004;95:736-740.
    • (2004) Cancer Sci , vol.95 , pp. 736-740
    • Tozawa, T.1    Tamura, G.2    Honda, T.3
  • 19
    • 30444454359 scopus 로고    scopus 로고
    • Promoter methylation profiles of tumor suppressor genes in intrahepatic and extrahepatic cholangiocarcinoma
    • Yang B, House MG, Guo M, Herman JG, Clark DP. Promoter methylation profiles of tumor suppressor genes in intrahepatic and extrahepatic cholangiocarcinoma. Mod Pathol. 2004;17:1-9.
    • (2004) Mod Pathol , vol.17 , pp. 1-9
    • Yang, B.1    House, M.G.2    Guo, M.3    Herman, J.G.4    Clark, D.P.5
  • 20
    • 0036056617 scopus 로고    scopus 로고
    • Genetic and epigenetic alterations of the INK4a-ARF pathway in cholangiocarcinoma
    • Tannapfel A, Sommerer F, Benicke M, et al. Genetic and epigenetic alterations of the INK4a-ARF pathway in cholangiocarcinoma. J Pathol. 2002;197:624-631.
    • (2002) J Pathol , vol.197 , pp. 624-631
    • Tannapfel, A.1    Sommerer, F.2    Benicke, M.3
  • 21
    • 0036735305 scopus 로고    scopus 로고
    • Aberrant CpG island methylation of multiple genes in intrahepatic cholangiocarcinoma
    • Lee S, Kim WH, Jung HY, Yang MH, Kang GH. Aberrant CpG island methylation of multiple genes in intrahepatic cholangiocarcinoma. Am J Pathol. 2002;161:1015-1022.
    • (2002) Am J Pathol , vol.161 , pp. 1015-1022
    • Lee, S.1    Kim, W.H.2    Jung, H.Y.3    Yang, M.H.4    Kang, G.H.5
  • 22
    • 0031943659 scopus 로고    scopus 로고
    • Assessment of expression of p53, MIB-1 (Ki-67 antigen) and argyrophil nucleolar organizer regions in carcinomas of the extrahepatic bile duct
    • Suto T, Sugai T, Nakamura S, et al. Assessment of expression of p53, MIB-1 (Ki-67 antigen) and argyrophil nucleolar organizer regions in carcinomas of the extrahepatic bile duct. Cancer. 1998;82:86-92.
    • (1998) Cancer , vol.82 , pp. 86-92
    • Suto, T.1    Sugai, T.2    Nakamura, S.3
  • 23
    • 0029849620 scopus 로고    scopus 로고
    • Cancer cell cycles
    • Sherr CJ. Cancer cell cycles. Science. 1996;274:1672-1677.
    • (1996) Science , vol.274 , pp. 1672-1677
    • Sherr, C.J.1
  • 24
    • 0029052951 scopus 로고
    • Tumor-derived p16 alleles encoding proteins defective in cell-cycle inhibition
    • Koh J, Enders GH, Dynlacht BD, Harlow E. Tumor-derived p16 alleles encoding proteins defective in cell-cycle inhibition. Nature. 1995;375:506-510.
    • (1995) Nature , vol.375 , pp. 506-510
    • Koh, J.1    Enders, G.H.2    Dynlacht, B.D.3    Harlow, E.4
  • 25
    • 0038146961 scopus 로고    scopus 로고
    • Hypermethylation of the p76 gene and lack of p16 expression in hepatoblastoma
    • Shim YH, Park HJ, Choi MS, et al. Hypermethylation of the p76 gene and lack of p16 expression in hepatoblastoma. Mod Pathol. 2003;16:430-436.
    • (2003) Mod Pathol , vol.16 , pp. 430-436
    • Shim, Y.H.1    Park, H.J.2    Choi, M.S.3
  • 28
    • 0028845142 scopus 로고
    • Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all human cancers
    • Herman JG, Merlo A, Mao L, et al. Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all human cancers. Cancer Res. 1995;55:4525-4530.
    • (1995) Cancer Res , vol.55 , pp. 4525-4530
    • Herman, J.G.1    Merlo, A.2    Mao, L.3
  • 30
    • 0033626213 scopus 로고    scopus 로고
    • Increase in the frequency of gene inactivation by hypermethylation in lung cancer during the process of metastasis and its relation to the status of p53
    • Seike M, Gemma A, Hosoya Y, et al. Increase in the frequency of gene inactivation by hypermethylation in lung cancer during the process of metastasis and its relation to the status of p53. Clin Cancer Res. 2000;6:4307-4313.
    • (2000) Clin Cancer Res , vol.6 , pp. 4307-4313
    • Seike, M.1    Gemma, A.2    Hosoya, Y.3
  • 31
    • 0037191509 scopus 로고    scopus 로고
    • Alterations in the p16/pRb cell cycle checkpoint occur commonly in primary and metastatic human prostatic cancer
    • Jarrard DF, Modder J, Fadden P, et al. Alterations in the p16/pRb cell cycle checkpoint occur commonly in primary and metastatic human prostatic cancer. Cancer Lett. 2002;185:191-199.
    • (2002) Cancer Lett , vol.185 , pp. 191-199
    • Jarrard, D.F.1    Modder, J.2    Fadden, P.3
  • 32
    • 4043112816 scopus 로고    scopus 로고
    • Differential impact of p16 inactivation by promoter methylation in non-small cell lung and colorectal cancer: Clinical implications
    • Gonzalez-Quevedo R, Garcia-Aranda C, Moran A, et al. Differential impact of p16 inactivation by promoter methylation in non-small cell lung and colorectal cancer: clinical implications. Int J Oncol. 2004;24:349-355.
    • (2004) Int J Oncol , vol.24 , pp. 349-355
    • Gonzalez-Quevedo, R.1    Garcia-Aranda, C.2    Moran, A.3
  • 33
    • 0036007249 scopus 로고    scopus 로고
    • BAX and p16INK4A are independent positive prognostic markers for advanced tumour stage of nonsmall cell lung cancer
    • Gessner C, Liebers U, Kuhn H, et al. BAX and p16INK4A are independent positive prognostic markers for advanced tumour stage of nonsmall cell lung cancer. Eur Respir J. 2002;19:134-140.
    • (2002) Eur Respir J , vol.19 , pp. 134-140
    • Gessner, C.1    Liebers, U.2    Kuhn, H.3
  • 34
    • 3042522794 scopus 로고    scopus 로고
    • Differences in loss of p16INK4 protein expression by promoter methylation between left- and right-sided primary colorectal carcinomas
    • Schneider-Stock R, Boltze C, Peters B, et al. Differences in loss of p16INK4 protein expression by promoter methylation between left- and right-sided primary colorectal carcinomas. Int J Oncol. 2003;23:1009-1013.
    • (2003) Int J Oncol , vol.23 , pp. 1009-1013
    • Schneider-Stock, R.1    Boltze, C.2    Peters, B.3
  • 35
    • 0035187023 scopus 로고    scopus 로고
    • p16/p14(ARF)cell cycle regulatory pathways in primary neuroblastoma: P16 expression is associated with advanced stage disease
    • Omura-Minamisawa M, Diccianni MB, Chang RC, et al. p16/p14(ARF)cell cycle regulatory pathways in primary neuroblastoma: p16 expression is associated with advanced stage disease. Clin Cancer Res. 2001;7:3481-3490.
    • (2001) Clin Cancer Res , vol.7 , pp. 3481-3490
    • Omura-Minamisawa, M.1    Diccianni, M.B.2    Chang, R.C.3
  • 38
    • 0024583738 scopus 로고
    • Long-term survival in carcinoma of the biliary tract: Analysis of the prognostic factors in 146 resection
    • Ouchi K, Matsuno S, Sato T. Long-term survival in carcinoma of the biliary tract: analysis of the prognostic factors in 146 resection. Arch Surg. 1989;124:248-252.
    • (1989) Arch Surg , vol.124 , pp. 248-252
    • Ouchi, K.1    Matsuno, S.2    Sato, T.3
  • 39
    • 0027493312 scopus 로고
    • Clinicopathologic factors influencing survival of patients with bile duct carcinoma: Multivariate statistical analysis
    • Bhuiya MMR, Nimura Y, Kamiya J, Kondo S, Nagino M, Hayakawa N. Clinicopathologic factors influencing survival of patients with bile duct carcinoma: multivariate statistical analysis. World J Surg. 1993;17:653-657.
    • (1993) World J Surg , vol.17 , pp. 653-657
    • Bhuiya, M.M.R.1    Nimura, Y.2    Kamiya, J.3    Kondo, S.4    Nagino, M.5    Hayakawa, N.6
  • 40
    • 0034212946 scopus 로고    scopus 로고
    • Loss of p16(INK4) protein, alone and together with loss of retinoblastoma protein, correlate with hepatocellular carcinoma progression
    • Hui AM, Shi YZ, Li X, Takayama T, Makuuchi M. Loss of p16(INK4) protein, alone and together with loss of retinoblastoma protein, correlate with hepatocellular carcinoma progression. Cancer Lett. 2000;154:93-99.
    • (2000) Cancer Lett , vol.154 , pp. 93-99
    • Hui, A.M.1    Shi, Y.Z.2    Li, X.3    Takayama, T.4    Makuuchi, M.5
  • 41
    • 0036742764 scopus 로고    scopus 로고
    • Expression of G1-S modulators (p53, p16, p27, cyclin D1, Rb) and Smad4/Dpc4 in intrahepatic cholangiocarcinoma
    • Kang YK, Kim WH, Jang JJ. Expression of G1-S modulators (p53, p16, p27, cyclin D1, Rb) and Smad4/Dpc4 in intrahepatic cholangiocarcinoma. Hum Pathol. 2002;33:877-883.
    • (2002) Hum Pathol , vol.33 , pp. 877-883
    • Kang, Y.K.1    Kim, W.H.2    Jang, J.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.