Design, synthesis, and binding affinities of potential positron emission tomography (PET) ligands for visualization of brain dopamine D3 receptors

Journal of Medicinal Chemistry

Volumn 49, Issue 1, 2006, Pages 358-365

  Leopoldo, Marcello ^a   Lacivita, Enza ^a   De Giorgio, Paola ^a   Colabufo, Nicola A ^a   Niso, Mauro ^a   Berardi, Francesco ^a   Perrone, Roberto ^a  

^a UNIVERSITY OF BARI   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON 11; DOPAMINE 3 RECEPTOR; N [4 [4 (2,3 DICHLOROPHENYL)PIPERAZIN 1 YL]BUTYL] 7 METHOXY 2 BENZOFURANCARBOXAMIDE; N [4 [4 (5 METHOXY 2 BENZISOXAZOLYL)PIPERAZIN 1 YL]BUTYL] 4 (1H IMIDAZOL 1 YL)BENZAMIDE; N [4 [4 (5 METHOXY 2 BENZISOXAZOLYL)PIPERAZIN 1 YL]BUTYL] 4 (4 MORPHOLINYL)BENZAMIDE; N [4 [4 (5 METHOXY 2 BENZISOXAZOLYL)PIPERAZIN 1 YL]BUTYL] 5 (2 FURANYL) 1H PYRAZOLE 3 CARBOXAMIDE; RADIOLIGAND; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CELL STRAIN CACO 2; CONTROLLED STUDY; DRUG DESIGN; DRUG RECEPTOR BINDING; DRUG UPTAKE; HUMAN; HUMAN CELL; LIPOPHILICITY; POSITRON EMISSION TOMOGRAPHY;

ANIMALS; BENZOFURANS; BRAIN; CACO-2 CELLS; DRUG DESIGN; HUMANS; LIGANDS; MOLECULAR STRUCTURE; PIPERAZINES; POSITRON-EMISSION TOMOGRAPHY; PROTEIN BINDING; RATS; RECEPTORS, DOPAMINE D3; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 30444439721     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm050734s     Document Type: Article

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