Synthesis and antiviral activity of novel C-methyl branched cyclopropyl nucleosides

Archives of Pharmacal Research

Volumn 26, Issue 9, 2003, Pages 679-685

  Eun, Yee Kwak ^a   Joon, Hee Hong ^b   Park, Youngja ^c   Bo, Gil Choi ^a  

^a Chonnam National University   (South Korea)

^b Chosun University   (South Korea)

^c Sookmyung Women's University   (South Korea)

Author keywords

Antiviral agent; Cyclopropyl nucleoside; Simmons Smith cyclopropanation

Indexed keywords

(1'S,2'S) 2 AMINO 9 ((2' HYDROXYETHYL 1' (METHYL)CYCLOPROP 1' YL)METHYL) 6 CHLOROPURINE; (1'S,2'S) 9 ((2' HYDROXYMETHYL 1' (METHYL)CYCLOPROP 1' YL)METHYL)ADENINE; (1'S,2'S)-2-AMINO-9-((2'-HYDROXYETHYL-1'-(METHYL)CYCLOPROP-1'-YL)METHYL)-6-CHLOROPURINE; (1'S,2'S)-9-((2'-HYDROXYMETHYL-1'-(METHYL)CYCLOPROP-1'-YL)METHYL)ADENINE; ADENINE; ANTIVIRUS AGENT; CYCLOPROPANE DERIVATIVE; GANCICLOVIR; PURINE DERIVATIVE; PURINE NUCLEOSIDE; RIBAVIRIN; ZIDOVUDINE;

ARTICLE; CHEMICAL STRUCTURE; COMPARATIVE STUDY; CYCLIZATION; CYTOMEGALOVIRUS; CYTOTOXICITY TEST; DRUG EFFECT; HERPES SIMPLEX VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1; KOREA; METHYLATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SYNTHESIS; X RAY CRYSTALLOGRAPHY;

ADENINE; ANTIVIRAL AGENTS; CRYSTALLOGRAPHY, X-RAY; CYCLIZATION; CYCLOPROPANES; CYTOMEGALOVIRUS; CYTOTOXICITY TESTS, IMMUNOLOGIC; GANCICLOVIR; HERPESVIRUS 1, HUMAN; HIV-1; KOREA; MAGNETIC RESONANCE SPECTROSCOPY; METHYLATION; MOLECULAR STRUCTURE; PURINE NUCLEOSIDES; PURINES; RIBAVIRIN; ZIDOVUDINE;

EID: 30444434575     PISSN: 02536269     EISSN: 02536269     Source Type: Journal    
DOI: 10.1007/bf02976674     Document Type: Article

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