Expression of apoptosis-related proteins in adenomyotic uteri treated with danazol and GnRH agonists

International Journal of Gynecological Pathology

Volumn 23, Issue 3, 2004, Pages 248-258

  Ueki, Ken ^a   Kumagai, Koji ^a   Yamashita, Hidetoshi ^a   Li, Zhong Lian ^a   Ueki, Minoro ^a   Otsuki, Yoshinori ^a  

^a OSAKA MEDICAL COLLEGE   (Japan)

Author keywords

Adenomyosis; Agonist; Apoptosis; Danazol; GnRH; Necrosis; Phosphorylated bcl 2 microsatellite instability

Indexed keywords

DANAZOL; DNA FRAGMENT; ESTROGEN RECEPTOR; FAS ANTIGEN; FAS LIGAND; GONADORELIN AGONIST; PROTEIN BAX; PROTEIN BCL 2;

ADENOMYOSIS; ADULT; APOPTOSIS; ARTICLE; ELECTROPHORESIS; FEMALE; GENE MUTATION; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MENSTRUAL CYCLE; MICROSATELLITE INSTABILITY; NICK END LABELING; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; TRANSMISSION ELECTRON MICROSCOPY;

ADENOMYOMA; ADULT; ANTIGENS, CD95; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; DANAZOL; DNA, NEOPLASM; ENDOMETRIAL NEOPLASMS; ESTROGEN ANTAGONISTS; FAS LIGAND PROTEIN; FEMALE; GONADOTROPIN-RELEASING HORMONE; HUMANS; MEMBRANE GLYCOPROTEINS; MENSTRUAL CYCLE; MIDDLE AGED; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-BCL-2; RECEPTORS, ESTROGEN; RECEPTORS, PROGESTERONE;

EID: 3042824847     PISSN: 02771691     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.pgp.0000130109.80359.57     Document Type: Article

References (32)

1. Ninomiya E, Ito Y, Shibata MA, et al. The activation of caspase-3 and DNA fragmentation in B Cells phagocytosed by macrophages. Med Electron Microsc 2003;36:87-93.
2. Okamura N, Ito Y, Shibata MA, et al. Fas-mediated apoptosis in human lens epithelial cells of cataracts associated with diabetic retinopathy. Med Electron Microsc 2002;35:234-41.
3. Otsuki Y, Misaki O, Sugimoto O, et al. Cyclic bcl-2 gene expression in human uterine endometrium during menstrual cycle. Lancet 1994;344:28-9.
4. Baatout S, Derradji H, Petitfour O, et al. Mechanisms of radioinduced apoptosis. Can J Physiol Pharmacol 2002;80:629-37.
5. Segal-Bendirdjian E, Hillion J, Belmokhtar CA. Current concepts on apoptotic signaling pathways: New targets for anticancer strategies. Bull Cancer 2003;90:9-17.
6. Hildebrandt B, Wust P, Ahlers O, et al. The cellular and molecular basis of hyperthermia. Crit Rev Oncol Hematol 2002;43:33-56.
7. Koester SK, Bolton WE. Differentiation and assessment of cell death. Clin Chem Lab Med 1999;37:311-7.
8. Yamashita H, Otsuki Y, Matsumoto K, et al. Fas ligand, Fas antigen and bcl-2 expression in human endometrium during the menstrual cycle. Mol Hum Reprod 1999;5:358-64.
9. Watanabe H, Kanzaki H, Narukawa S, et al. Bcl-2 and Fas expression in eutopic and ectopic human endometrium during the menstrual cycle in relation to endometrial cell apoptosis. Am J Obstet Gynecol 1997;176:360-8.
10. Cohen I, Shapira J, Beyth Y, et al. Estrogen and progesterone receptors of adenomyosis in postmenopausal breast cancer patients treated with tamoxifen. Gynecol Obstet Invest 1998;45:126-31.
11. Imaoka I, Ascher SM, Sugimura K, et al. MR imaging of diffuse adenomyosis: changes after GnRH-analog therapy. J Magn Reson Imaging 2002;15:285-90.
12. Propst AM, Quade BJ, Gargiulo AR, et al. Adenomyosis demonstrates increased expression of the casic fibroblast growth factor receptor/ligand system compared with autologous endometrium. Menopause 2001;8:368-71.
13. Konopka B, Skasko E, Kluska A, et al. Changes in the concentrations of receptors of insulin-like growth factor-I, epithelial growth factor, oestrogens and progestagens in adenomyosis foci, endometrium and myometrium of women during menstrual cycle. Eur J Gynaecol Oncol 1998;19:93-7.
14. Matalliotakis IM, Athanassakis I, Goumenou AG, et al. The possible anti-inflammatory role of circulating human leukocyte antigen levels in women with endometriosis after treatment with danazol and leuprorelin acetate depot. Mediators Inflamm 2001;10:75-80.
15. Poncelet C, Leblanc M, Walker-Combrouze F, et al. Expression of cadherins and Cd44 isoforms in human endometrium and peritoneal endometriosis. Acta Obstet Gynecol Scand 2002;81:195-203.
16. Haldar S, Jena N, Croce CM. Inactivation of bcl-2 by phosphorylation. Proc Natl Acad Sci U S A 1995;92:4507-11.
17. Koshiyama M, Suzuki A, Ozawa M, et al. Adenocarcinomas arising from uterine adenomyosis: A report of four cases. Int J Gynecol Pathol 2002;21:239-45.
18. Pandis N, Karaiskos C, Bardi G, et al. Chromosome analysis of uterine adenomyosis. Detection of the leiomyoma-associated Del(7q) in three cases. Cancer Genet Cytogenet 1995;80:118-20.
19. Seidman JD, Kjerulff KH. Pathologic findings from the Maryland Women's Health Study: practice patterns in the diagnosis of adenomyosis. Int J Gynecol Pathol 1996;15:217-21.
20. Ferenczy A. Pathophysiology of adenomyosis. Hum Reprod Update 1998;4:312-22.
21. Grasl-Kraupp B, Ruttkay-Nedecky B, Koudelka H, et al. In situ detection of fragmented DNA (TUNEL assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: a cautionary note. Hepatology 1995;21:1465-8.
22. Hayashi R, Ito Y, Matsumoto K, et al. Quantitative differentiation of both free 3′-OH and 5′-OH DNA ends between heat-induced apoptosis and necrosis. J Histochem Cytochem 1998;46:1051-59.
23. Makino R, Yazyu H, Kishimoto Y, et al. F-SSCP: Fluorescence-based polymerase chain reaction-single-strand conformation polymorphism (PCR-SSCP) analysis. PCR Methods Appl 1992;2:10-3.
24. Makino R, Kaneko K, Kurahashi T, et al. Detection of mutation of the p53 gene with high sensitivity by fluorescence-based PCR-SSCP analysis using low-pH buffer and an automated DNA sequencer in a large number of DNA samples. Mutat Res 2000;452:83-90.
25. Ellison J, Squires G, Crutchfield C, et al. Detection of mutations and polymorphisms using fluorescence-based dideoxy fingerprinting (F-Ddf). Biotechniques 1994;17:742-3, 46-7, 48-53.
26. Chiaravalli AM, Furlan D, Facco C, et al. Immunohistochemical pattern of Hmsh2/Hmlh1 in familial and sporadic colorectal, gastric, endometrial and ovarian carcinomas with onstability in microsatellite sequences. Virchows Arch 2001;438:39-48.
27. Majno G, Joris I. Apoptosis, oncosis, and necrosis. An overview of cell death. Am J Pathol 1995;146:3-15.
28. Mutter GL, Wada H, Faquin WC, et al. K-ras mutations appear in the premalignant phase of both microsatellite stable and unstable endometrial carcinogenesis. Mol Pathol 1999;52:257-62.
29. Simpson JL, Bischoff FZ. Heritability and molecular genetic studies of endometriosis. Ann N Y Acad Sci 2002;955:239-51; discussion 293-5, 396-406.
30. Morgante G, Ditto A, La Marca A, et al. Low-dose danazol after combined surgical and medical therapy reduces the incidence of pelvic pain in women with moderate and severe endometriosis. Hum Reprod 1999;14:2371-4.
31. Rodi DJ, Janes RW, Sanganee HJ, et al. Screening of a library of phage-displayed peptides identifies human bcl-2 as a taxol-binding protein. J Mol Biol 1999;285:197-203.
32. Wang S, Wang Z, Boise L, et al. Loss of the bcl-2 phosphorylation loop Domain increases resistance of human leukemia cells (U937) to paclitaxel-mediated mitochondrial dysfunction and apoptosis. Biochem Biophys Res Commun 1999;259:67-72.