Salmonella impairs RILP recruitment to Rab7 during maturation of invasion vacuoles

Molecular Biology of the Cell

Volumn 15, Issue 7, 2004, Pages 3146-3154

  Harrison, Rene E ^a   Brumell, John H ^b   Khandani, Arian ^a   Bucci, Cecilia ^c   Scott, Cameron C ^b   Jiang, Xiuju ^b   Finlay, B Brett ^d   Grinstein, Sergio ^b  

^a UNIVERSITY OF TORONTO   (Canada)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

^c UNIVERSITY OF SALENTO   (Italy)

^d UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

DYNEIN ADENOSINE TRIPHOSPHATASE; KINESIN; PROTEIN; RAB PROTEIN; RAB7 INTERACTING LYSOSOMAL PROTEIN; RAB7 PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL INFECTION; BACTERIAL REPRODUCTION; BACTERIAL SURVIVAL; CELL VACUOLE; CONTROLLED STUDY; ENDOSOME; EPITHELIUM CELL; HELA CELL; HUMAN; HUMAN CELL; LYSOSOME; MICROFILAMENT; MICROTUBULE; MICROTUBULE ORGANIZING CENTER; PRIORITY JOURNAL; SALMONELLA CONTAINING VACUOLE; SALMONELLA ENTERICA; SALMONELLA INDUCED FILAMENT;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; BACTERIAL PROTEINS; CARRIER PROTEINS; DYNEIN ATPASE; GLYCOPROTEINS; HELA CELLS; HUMANS; KINESIN; MITOCHONDRIA; RAB GTP-BINDING PROTEINS; SALMONELLA TYPHIMURIUM; VACUOLES;

BACTERIA (MICROORGANISMS); NEGIBACTERIA; SALMONELLA; SALMONELLA ENTERICA; STRAWBERRY CRINKLE VIRUS;

EID: 3042801832     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.E04-02-0092     Document Type: Article

References (26)

1. Amer, A.O., and Swanson, M.S. (2002). A phagosome of one's own: a microbial guide to life in the macrophage. Curr. Opin. Microbiol. 5, 56-61.
2. Beuzon, C.R., Salcedo, S.P., and Holden, D.W. (2002). Growth and killing of a Salmonella enterica serovar Typhimurium sifA mutant strain in the cytosol of different host cell lines. Microbiology 148, 2705-2715.
3. Boucrot, E., Beuzon, C.R., Holden, D.W., Gorvel, J.P., and Meresse, S. (2003). Salmonella typhimurium SifA effector protein requires its membrane-anchoring C-terminal hexapeptide for its biological function. J. Biol. Chem. 278, 14196-14202.
4. Brumell, J.H., Kujat-Choy, S., Brown, N.F., Vallance B.A., Knodler, L.A., and Finlay, B.B. (2003). SopD2 is a novel type III secreted effector of Salmonella typhimurium that targets late endocytic compartments upon delivery into host cells. Traffic 4, 36-48.
5. Brumell, J.H., Rosenberger, C.M., Gotto, G.T., Marcus, S.L., and Finlay, B.B. (2001a). SifA permits survival and replication of Salmonella typhimurium in murine macrophages. Cell Microbiol. 3, 75-84.
6. Brumell, J.H., Tang, P., Mills, S.D., and Finlay, B.B. (2001b). Characterization of Salmonella-induced filaments (Sifs) reveals a delayed interaction between Salmonella-containing vacuoles and late endocytic compartmemts. Traffic 2, 643-653.
7. Brumell, J.H., Tang, P., Zaharik, M.L., and Finlay, B.B. (2002). Disruption of the Salmonella-containing vacuole leads to increased replication of Salmonella enterica serovar typhimurium in the cytosol of epithelial cells. Infect. Immun. 70, 3264-3270.
8. Bucci, C., Thomsen, P., Nicoziani, P., McCarthy, J., and van Deurs, B. (2000). Rab 7, a key to lysosome biogenesis. Mol. Biol. Cell 11, 467-480.
9. Cantalupo, G., Alifano, P., Roberti, V., Bruni, C.B., and Bucci, C. (2001). Rab-interacting lysosomal protein (RILP): the Rab7 effector required for transport to lysosomes. EMBO J. 20, 683-693.
10. Garcia-del Portillo, F., and Finlay, B.B. (1995). Targeting of Salmonella typhimurium to vesicles containing lysosomal membrane glycoproteins bypasses compartments with mannose 6-phosphate receptors. J. Cell Biol. 129, 81-97.
11. Garcia-del Portillo, F., Zwick, M.B., Leung, KY., and Finlay, B.B. (1993). Salmonella induces the formation of filamentous structures containing lysosomal membrane glycoproteins in epithelial cells. Proc. Natl. Acad. Sci. USA 90, 10544-10548.
12. Guignot, J., Caron, E., Beuzon, C., Bucci, C., Kagan, J., Roy, C., and Holden, D.W. (2004). Microtubule motors control membrane dynamics of Salmonella-containing vacuoles. J. Cell Sci. 117, 1033-1045.
13. Harrison, R.E., Bucci, C., Vieira, O.V., Schroer, T.A., and Grinstein, S. (2003). Phagosomes fuse with late endosomes and/or lysosomes by extension of membrane protrusions along microtubules: role of Rab7 and RILP. Mol. Cell. Biol. 23, 6494-6506.
14. Hensel, M. (2000). Salmonella pathogenicity island 2. Mol. Microbiol. 36, 1015-1023.
15. Hopkins, S.C., Vale, R.D., and Kuntz, I.D. (2000). Inhibitors of kinesin activity from structure-based computer screening. Biochemistry 39, 2805-2814.
16. Jordens, I., Femandez-Borja, M., Marsman, M., Dusseljee, S., Janssen, L., Calafat, J., Janssen, H., Wubbolts, R., and Neefjes, J. (2001). The Rab7 effector protein RILP controls lysosomal transport by inducing the recruitment of dynein-dynactin motors. Curr. Biol. 11, 1680-1685.
17. Meresse, S., Steele-Mortimer, O., Finlay, B.B., and Gorvel, J.P. (1999). The rab7 GTPase controls the maturation of Salmonella typhimurium-containing vacuoles in HeLa cells. EMBO J. 18, 4394-4403.
18. Miller, S.I., and Mekalanos, J.J. (1990). Constitutive expression of the phoP regulon attenuates Salmonella virulence and survival within macrophages. J. Bacteriol. 172, 2485-2490.
19. Pfeifer, C.G., Marcus, S.L., Steele-Mortimer, O., Knodler, L.A., and Finlay, B.B. (1999). Salmonella typhimurium virulence genes are induced upon bacterial invasion into phagocytic and nonphagocytic cells. Infect. Immun. 67, 5690-5698.
20. Quintyne, N.J., Gill, S.R., Eckley, D.M., Crego, C.L., Compton, D.A., and Schroer, T.A. (1999). Dynactin is required for microtubule anchoring at centrosomes. J. Cell Biol. 147, 321-334.
21. Scott, C.C., Cuellar-Mata, P., Matsuo, T., Davidson, H.W., and Grinstein, S. (2002). Role of 3-phosphoinositides in the maturation of Salmonella-containing vacuoles within host cells. J. Biol. Chem. 277, 12770-12776.
22. Steele-Mortimer, O., Meresse, S., Gorvel, J.P., Toh, B.H., and Finlay, B.B. (1999). Biogenesis of Salmonella typhimurium-containing vacuoles in epithelial cells involves interactions with the early endocytic pathway. Cell Microbiol. 1, 33-49.
23. Stein, M.A., Leung, K.Y., Zwick, M., Garcia-del Portillo, F., and Finlay, B.B. (1996). Identification of a Salmonella virulence gene required for formation of filamentous structures containing lysosomal membrane glycoproteins within epithelial cells. Mol. Microbiol. 20, 151-164.
24. Tsolis, R.M., Kingsley, R.A., Townsend, S.M., Ficht, T.A., Adams, L.G., and Baumler, A.J. (1999). Of mice, calves, and men. Comparison of the mouse typhoid model with other Salmonella infections. Adv. Exp. Med. Biol. 473, 261-274.
25. Waterman, S.R., and Holden, D.W. (2003). Functions and effectors of the Salmonella pathogenicity island 2 type III secretion system. Cell Microbiol. 5, 501-511.
26. Wubbolts, R., Fernandez-Borja, M., Jordens, I., Reits, E., Dusseljee, S., Echeverri, C., Vallee, R.B., and Neefjes, J. (1999). Opposing motor activities of dynein and kinesin determine retention and transport of MHC class II-containing compartments. J. Cell Sci. 112, 785-795.