A QSAR study on inhibitory activities of 1-phenylbenzimidazoles against the platelet-derived growth factor receptor

Bioorganic and Medicinal Chemistry

Volumn 12, Issue 15, 2004, Pages 4009-4015

  Zhong, Chongli ^a   He, Jingtao ^a   Xue, Chunyu ^a   Li, Yajun ^a  

^a BEIJING UNIVERSITY OF CHEMICAL TECHNOLOGY   (China)

Author keywords

Connectivity index; QSAR; The platelet derived growth factor receptor

Indexed keywords

ANTINEOPLASTIC AGENT; IMIDAZOLE DERIVATIVE; PLATELET DERIVED GROWTH FACTOR RECEPTOR;

ARTICLE; DRUG ACTIVITY; MOLECULAR MODEL; PREDICTION; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; BENZIMIDAZOLES; DRUG DESIGN; ENZYME INHIBITORS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; RECEPTORS, PLATELET-DERIVED GROWTH FACTOR;

EID: 3042795630     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2004.06.002     Document Type: Article

References (24)

1. Claesson-Welsl L. Cytokines. 5:1993;31
2. Meyer-Ingold W., Eichner W. Cell Biol. Int. 19:1995;389
3. Palmer B.D., Smaill J.B., Boyd M., Boschelli D.H., Doherty A.M., Hamby J.M., Khatana S.S., Kramer J.B., Kraker A.J., Panek R.L., Lu G.H., Dahring T.K., Winters R.T., Showalter H.D.H., Denny W.A. J. Med. Chem. 41:1998;5457
4. Palmer B.D., Kraker A.J., Hartl B.G., Panopoulos A.D., Panek R.L., Batley B.L., Lu G.H., Trumpp-Kallmeyer S., Showalter H.D.H., Denny W.A. J. Med. Chem. 42:1999;2373
5. Dolle R.E., Dunn J.A., Bobko M., Singh B., Kuster J.E., Baizman E., Harris A.L., Sawutz S.G., Miller D., Wang S., Faltynek C.R., Xie W., Sarup J., Bode C.E., Pagani E.D., Silver P.J. J. Med. Chem. 37:1994;2627
6. Maguire M.P., Sheets K.R., McVety K., Spada A.P., Ziberstein A.A. J. Med. Chem. 37:1994;29
7. Oblak M., Randić M., Solmajer T. J. Chem. Inf. Comput. Sci. 40:2000;994
8. Pierre D., Michel L., David S.G. J. Med. Chem. 43:2000;4098
9. Zhu L.L., Hou T.J., Chen L.R., Xu X.J. J. Chem. Inf. Comput. Sci. 41:2001;1032
10. Kurup A., Garg R., Hansch C. Chem. Rev. 101:2001;2573
11. Naumann T., Matter T. J. Med. Chem. 45:2002;2366
12. Shen Q., Lu Q.-Z., Jiang J.-H., Shen G.-L., Yu R.-Q. Eur. J. Pharm. Sci. 20:2003;63
13. Kier L.B., Hall L.H. Molecular Connectivity in Chemistry and Drug Research. 1976;Academic, New York
14. Kier L.B., Hall L.H. Molecular Connectivity in Structure-Activity Analysis. 1986;Wiley, New York
15. Zhong C., Hu Q. J. Pharm. Sci. 92:2003;2284
16. Yang C., Zhong C. J. Chem. Inf. Comput. Sci. 43:2003;1998
17. He J., Zhong C. Eur. Polym. J. 39:2003;1297
18. Yang C., Zhao L., Zhong C. Int. J. Thermophys. 24:2003;1651
19. Zhong C., Yang C. J. Polym. Sci.: Polym. Phys. Ed. 40:2002;401
20. Zhong C., Yang C., Li Q. Ind. Eng. Chem. Res. 41:2002;2826
21. Liu D., Zhong C. Polym. J. 34:2002;954
22. Li, Y.; Hu, Q.; Zhong, C. Ind. Eng. Chem. Res., in press
23. Randić M. J. Comput. Chem. 12:1991;970
24. Randić M. J. Mol. Graph. Model. 20:2001;19