3D QSAR Analyses of Novel Tyrosine Kinase Inhibitors Based on Pharmacophore Alignment

Journal of Chemical Information and Computer Sciences

Volumn 41, Issue 4, 2001, Pages 1032-1040

  Zhu, L L ^a   Hou, T J ^a   Chen, L R ^b   Xu, X J ^a  

^a PEKING UNIVERSITY   (China)

^b PEKING UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

COMPUTER SIMULATION; HYDROGEN BONDS; HYDROPHOBICITY; MOLECULAR GRAPHICS; MOLECULES; OXYGEN;

MOLECULAR FIELD ANALYSIS (MFA);

PROTEINS;

BENZYLIDENE DERIVATIVE; ENZYME INHIBITOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; INDOLE DERIVATIVE; PROTEIN TYROSINE KINASE;

ARTICLE; BIOLOGICAL MODEL; CHEMICAL MODEL; CHEMICAL STRUCTURE; COMPARATIVE STUDY; DRUG EFFECT; METABOLISM; QUANTITATIVE STRUCTURE ACTIVITY RELATION; STEREOISOMERISM;

BENZYLIDENE COMPOUNDS; ENZYME INHIBITORS; INDOLES; MODELS, BIOLOGICAL; MODELS, CHEMICAL; MOLECULAR STRUCTURE; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, ERBB-2; STEREOISOMERISM;

EID: 0035385131     PISSN: 00952338     EISSN: None     Source Type: Journal    
DOI: 10.1021/ci010002i     Document Type: Article

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