Patterns of resistance and DHFR/DHPS genotypes of Plasmodium falciparum in rural Tanzania prior to the adoption of sulfadoxine-pyrimethamine as first-line treatment

Transactions of the Royal Society of Tropical Medicine and Hygiene

Volumn 98, Issue 6, 2004, Pages 347-353

  Eriksen, Jaran ^a,d   Mwankusye, S ^b   Mduma, S ^b   Kitua, A ^b   Swedberg, G ^c   Tomson, G ^d   Gustafsson, L L ^a   Warsame, M ^d  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (Tanzania)

^c UPPSALA UNIVERSITY   (Sweden)

^d KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Chloroquine; Drug resistance; Malaria; Molecular markers; Plasmodium falciparum; Policy change; Sulfadoxine pyrimethamine; Tanzania

Indexed keywords

CHLOROQUINE; DIHYDROFOLATE REDUCTASE; DIHYDROPTEROATE SYNTHASE; FANSIDAR; HEMOGLOBIN; ANTIMALARIAL AGENT; PYRIMETHAMINE; SULFADOXINE; SULFADOXINE-PYRIMETHAMINE;

ARTICLE; CONTROLLED STUDY; CONVALESCENCE; DRUG BLOOD LEVEL; DRUG HALF LIFE; DRUG RESPONSE; FEMALE; GENE MUTATION; GENOTYPE; HUMAN; INFANT; MAJOR CLINICAL STUDY; MALARIA FALCIPARUM; MALE; NONHUMAN; PARASITOLOGY; PATIENT MONITORING; PLASMODIUM FALCIPARUM; PRESCHOOL CHILD; RANDOMIZATION; RURAL AREA; STATISTICAL SIGNIFICANCE; TANZANIA; TREATMENT OUTCOME; ANIMAL; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; DEVELOPING COUNTRY; DRUG COMBINATION; DRUG EFFECT; DRUG RESISTANCE; GENETICS; HEALTH; POINT MUTATION; RANDOMIZED CONTROLLED TRIAL;

PLASMODIUM FALCIPARUM;

ANIMALS; ANTIMALARIALS; CHILD, PRESCHOOL; CHLOROQUINE; DEVELOPING COUNTRIES; DIHYDROPTEROATE SYNTHASE; DRUG COMBINATIONS; DRUG RESISTANCE; FEMALE; GENOTYPE; HUMANS; INFANT; MALARIA, FALCIPARUM; MALE; PLASMODIUM FALCIPARUM; POINT MUTATION; PYRIMETHAMINE; RURAL HEALTH; SULFADOXINE; TANZANIA; TETRAHYDROFOLATE DEHYDROGENASE;

EID: 3042784232     PISSN: 00359203     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.trstmh.2003.10.010     Document Type: Article

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