메뉴 건너뛰기




Volumn 21, Issue 6, 2004, Pages 1047-1054

Simple rules defining the potential of compounds for transdermal delivery or toxicity

Author keywords

multivariate data analysis; quantitative structure activity relationships; transdermal absorption

Indexed keywords

DRUG;

EID: 3042764452     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:PHAM.0000029295.38564.e1     Document Type: Article
Times cited : (62)

References (17)
  • 1
    • 0026606514 scopus 로고
    • Predicting skin permeability
    • R. Potts and R. Guy. Predicting skin permeability. Pharm. Res. 9:663-669 (1992).
    • (1992) Pharm. Res. , vol.9 , pp. 663-669
    • Potts, R.1    Guy, R.2
  • 2
    • 0028013532 scopus 로고
    • Ab initio prediction of human skin permeability coefficients
    • W. Pugh and J. Hadgraft. Ab initio prediction of human skin permeability coefficients. Int. J. Pharm. 103:163-178 (1994).
    • (1994) Int. J. Pharm. , vol.103 , pp. 163-178
    • Pugh, W.1    Hadgraft, J.2
  • 3
    • 0028966130 scopus 로고
    • The factors that influence skin penetration of solutes
    • M. Abraham, H. Chadha, and R. Mitchell. The factors that influence skin penetration of solutes. J. Pharm. Pharmacol. 47:8-16 (1995).
    • (1995) J. Pharm. Pharmacol. , vol.47 , pp. 8-16
    • Abraham, M.1    Chadha, H.2    Mitchell, R.3
  • 4
    • 0029582936 scopus 로고
    • Epidermal permeability-penetrant structure relationships: 1. An analysis of methods of predicting penetration of monofunctional solutes from aqueous solutions
    • M. Roberts, W. Pugh, J. Hadgraft, and A. Watkinson. Epidermal permeability-penetrant structure relationships: 1. An analysis of methods of predicting penetration of monofunctional solutes from aqueous solutions. Int. J. Pharm. 126:219-233 (1995).
    • (1995) Int. J. Pharm. , vol.126 , pp. 219-233
    • Roberts, M.1    Pugh, W.2    Hadgraft, J.3    Watkinson, A.4
  • 5
    • 0029768028 scopus 로고    scopus 로고
    • Epidermal permeability-penetrant structure relationships: 3. The effect of hydrogen bonding interactions and molecular size on diffusion across the stratum corneum
    • W. Pugh, M. Roberts, and J. Hadgraft. Epidermal permeability-penetrant structure relationships: 3. The effect of hydrogen bonding interactions and molecular size on diffusion across the stratum corneum. Int. J. Pharm. 138:149-165 (1996).
    • (1996) Int. J. Pharm. , vol.138 , pp. 149-165
    • Pugh, W.1    Roberts, M.2    Hadgraft, J.3
  • 6
    • 0029950564 scopus 로고    scopus 로고
    • Epidermal permeability: Penetrant structure relationships. 2. The effect of H-bonding groups in penetrants on their diffusion through the stratum corneum
    • M. Roberts, W. Pugh, and J. Hadgraft. Epidermal permeability: penetrant structure relationships. 2. The effect of H-bonding groups in penetrants on their diffusion through the stratum corneum. Int. J. Pharm. 132:23-32 (1996).
    • (1996) Int. J. Pharm. , vol.132 , pp. 23-32
    • Roberts, M.1    Pugh, W.2    Hadgraft, J.3
  • 8
    • 0033995212 scopus 로고    scopus 로고
    • Epidermal permeability-penetrant structure relationships: 4, QSAR of permeant diffussion across human stratum in terms of molecular weight, H-bonding and electronic charge
    • W. Pugh, I. Degim, and J. Hadgraft. Epidermal permeability-penetrant structure relationships: 4, QSAR of permeant diffussion across human stratum in terms of molecular weight, H-bonding and electronic charge. Int. J. Pharm. 197:203-211 (2000).
    • (2000) Int. J. Pharm. , vol.197 , pp. 203-211
    • Pugh, W.1    Degim, I.2    Hadgraft, J.3
  • 9
    • 0035901712 scopus 로고    scopus 로고
    • The effect of structural QSAR parameters on skin penetration
    • T. Ghafourian and S. Fooladi. The effect of structural QSAR parameters on skin penetration. Int. J. Pharm. 217:1-11 (2001).
    • (2001) Int. J. Pharm. , vol.217 , pp. 1-11
    • Ghafourian, T.1    Fooladi, S.2
  • 10
    • 0029887895 scopus 로고    scopus 로고
    • Quantitative structure-activity relationships (QSARs) for skin corrosivity of organic acids, bases and phenols: Principal components and neural network analysis of extended datasets
    • M. Barratt. Quantitative structure-activity relationships (QSARs) for skin corrosivity of organic acids, bases and phenols: principal components and neural network analysis of extended datasets. Toxicology In Vitro 10:85-94 (1996).
    • (1996) Toxicology in Vitro , vol.10 , pp. 85-94
    • Barratt, M.1
  • 11
    • 0041573625 scopus 로고
    • Linear solvation energy relationship. 23. A comprehensive collection of the solvatochromic parameters and some methods for simplifying the generalized solvatochromic equation
    • M. Kamlet, J. Abboud, M. Abraham, and R. Taft. Linear solvation energy relationship. 23. A comprehensive collection of the solvatochromic parameters and some methods for simplifying the generalized solvatochromic equation. J. Org. Chem. 48:2877-2887 (1983).
    • (1983) J. Org. Chem. , vol.48 , pp. 2877-2887
    • Kamlet, M.1    Abboud, J.2    Abraham, M.3    Taft, R.4
  • 12
    • 0040524262 scopus 로고    scopus 로고
    • Estimation of molecular linear free energy relation descriptors using a group contribution approach
    • J. Platts, D. Butina, M. Abraham, and A. Hersey. Estimation of molecular linear free energy relation descriptors using a group contribution approach. J. Chem. Info. Comp. Sci. 39:835-845 (1999).
    • (1999) J. Chem. Info. Comp. Sci. , vol.39 , pp. 835-845
    • Platts, J.1    Butina, D.2    Abraham, M.3    Hersey, A.4
  • 13
    • 0035289779 scopus 로고    scopus 로고
    • Experimental and computational appoaches to estimate solubility and permeability in drug discovery and development settings
    • C. Lipinski, F. Lombardo, B. Dominy, and P. Feeney. Experimental and computational appoaches to estimate solubility and permeability in drug discovery and development settings. Adv. Drug Del. Rev. 46:3-26 (2001).
    • (2001) Adv. Drug Del. Rev. , vol.46 , pp. 3-26
    • Lipinski, C.1    Lombardo, F.2    Dominy, B.3    Feeney, P.4
  • 14
    • 2342599148 scopus 로고    scopus 로고
    • Molecular size as the main determinant of solute maximum flux across the skin
    • B. Magnusson, Y. Anissimov, S. Cross, and M. Roberts. Molecular size as the main determinant of solute maximum flux across the skin. J. Invest. Dermatol. 122:993-999 (2004).
    • (2004) J. Invest. Dermatol. , vol.122 , pp. 993-999
    • Magnusson, B.1    Anissimov, Y.2    Cross, S.3    Roberts, M.4
  • 16
    • 0036323878 scopus 로고    scopus 로고
    • Evaluation of a rule base for identifying contact allergens by using a regulatory database: Comparison of data on chemicals notified in the European Union with "structural alerts" used in the DEREK expert system
    • S. Zinke, I. Gerner, and E. Schlede. Evaluation of a rule base for identifying contact allergens by using a regulatory database: Comparison of data on chemicals notified in the European Union with "structural alerts" used in the DEREK expert system. Altern. Lab Anim. 30:285-298 (2002).
    • (2002) Altern. Lab Anim. , vol.30 , pp. 285-298
    • Zinke, S.1    Gerner, I.2    Schlede, E.3
  • 17
    • 0037331609 scopus 로고    scopus 로고
    • Fuzzy modelling of skin permeability coefficients
    • A. K. Pannier, R. M. Brand, D. D. Jones. Fuzzy modelling of skin permeability coefficients. Pharm. Res. 20:143-148 (2003).
    • (2003) Pharm. Res. , vol.20 , pp. 143-148
    • Pannier, A.K.1    Brand, R.M.2    Jones, D.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.