Structure of a site specific major groove (2S,3S)-N6-(2,3,4- trihydroxybutyl)-2′-deoxyadenosyl DNA adduct of butadiene diol epoxide

Chemical Research in Toxicology

Volumn 17, Issue 6, 2004, Pages 717-730

  Scholdberg, Tandace A ^a   Nechev, Lubomir V ^a,b   Merritt, W Keither ^a   Harris, Thomas M ^a   Harris, Constance M ^a   Lloyd, R Stephen ^a,c   Stone, Michael P ^a  

^a VANDERBILT INGRAM CANCER CENTER   (United States)

^b ALNYLAM PHARMACEUTICALS   (United States)

^c OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,3 BUTADIENE DERIVATIVE; ADENINE DERIVATIVE; BUTADIENE DIEPOXIDE; BUTADIENE DIOL EPOXIDE; CARCINOGEN; DEOXYADENOSINE DERIVATIVE; DEOXYRIBOSE; DNA; DNA POLYMERASE; EPOXIDE; HYDROXYL GROUP; N 6 (2,3,4 TRIHYDROXYBUTYL) 2' DEOXYADENOSINE; OLIGODEOXYNUCLEOTIDE; PROTON; STYRENE; UNCLASSIFIED DRUG;

ALKYLATION; ARTICLE; BASE PAIRING; CALCULATION; CHEMICAL STRUCTURE; DNA ADDUCT; HYDROGEN BOND; METABOLITE; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEAR OVERHAUSER EFFECT; ONCOGENE N RAS; SITE DIRECTED MUTAGENESIS;

ALKYLATION; DEOXYADENOSINES; DNA ADDUCTS; DNA-DIRECTED DNA POLYMERASE; EPOXY COMPOUNDS; GENES, RAS; GLYCOLS; HYDROGEN BONDING; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; MUTAGENESIS, SITE-DIRECTED; OLIGODEOXYRIBONUCLEOTIDES; POLY U;

ESCHERICHIA COLI;

EID: 3042723930     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx034271+     Document Type: Article

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