Estrogen and progesterone improve scopolamine-induced impairment of spatial memory

Journal of Medical and Dental Sciences

Volumn 51, Issue 1, 2004, Pages 89-98

  Tanabe, Fumiko ^a   Miyasaka, Naoyuki ^a   Kubota, Toshiro ^a   Aso, Takeshi ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

Estrogen; Progesterone; Radial maze; Scopolamine; Working memory

Indexed keywords

ESTROGEN; MUSCARINIC RECEPTOR BLOCKING AGENT; PROGESTERONE; SCOPOLAMINE;

ANALYSIS OF VARIANCE; ANIMAL; ARTICLE; BLOOD; CHEMICALLY INDUCED DISORDER; COMPARATIVE STUDY; DELAYED RELEASE FORMULATION; DRUG EFFECT; DRUG IMPLANT; ESTROGEN THERAPY; FEMALE; MAZE TEST; MEMORY; MEMORY DISORDER; OVARIECTOMY; RAT; SPRAGUE DAWLEY RAT;

ANALYSIS OF VARIANCE; ANIMALS; DELAYED-ACTION PREPARATIONS; DRUG IMPLANTS; ESTROGEN REPLACEMENT THERAPY; ESTROGENS; FEMALE; MAZE LEARNING; MEMORY; MEMORY DISORDERS; MUSCARINIC ANTAGONISTS; OVARIECTOMY; PROGESTERONE; RATS; RATS, SPRAGUE-DAWLEY; SCOPOLAMINE;

EID: 3042701662     PISSN: 13428810     EISSN: 13428810     Source Type: Journal    
DOI: None     Document Type: Article

References (55)

1. Writing group for the Women's Health Initiative Investigators. Risks and Benefits of Estrogen Plus Progestin in Healthy Postmenopausal Women. Principal Results From the Women's Health Initiative Randomized Controlled Trial. JAMA. 2002;3:288.
2. McEwen BS, Alves SE. Estrogen actions in the central nervous system. Endocrine reviews 1999;20:279-307.
3. Luine VN. Estradiol increases choline acetyltransferase activity in specific basal forebrain nuclei and projection areas of female rats. Exp Neurol 1985;89:484-490.
4. Wu X, Glinn MA, Ostrowski NL, et al. Raloxifene and estradiol benzoate both fully restore hippocampal choline acetyltransferase activity in ovariectomized rats. Brain Res 1999;847:98-104.
5. Gibbs RB. Effect of gonadal hormone replacement on measures of basal forebrain cholinergic function. Neuroscience 2000;101:931-938.
6. Bowen DM, Smith CB, White P, et al. Chemical pathology of this organic dementias: Quantitative estimation of cellular changes in post-mortem brains. Brain 1977;100:427-453.
7. Wang PN, Liao SQ, Liu RS, et al. Effects of estrogen on cognition, mood, and cerebral blood flow in AD, a controlled study. Neurology 2000;54:2061-2066.
8. Resnick SM, Maki PM, Golski S, et al. Effects of estrogen replacement therapy on PET cerebral blood flow and neuropsychological performance. Horm. Behav 1998;34:171-182.
9. Wolf OT, Kudielka BM, Hellhammer DH, et al. Two weeks of transdermal estradiol treatment in postmenopausal elderly women and its effect on memory and mood: verbal memory changes are associated with the treatment induced estradiol levels. Psychoneuroendocrinology 1999;24:727-741.
10. Henderson VW, Paganini-Hill A, Miller BL, et al. Estrogen for Altzheimer's disease in women, randomized, double-blind, placebo-controlled trial. Neurology 2000;54:195-301.
11. Schneider LS, Farlow MR, Henderson VW, et al. Effects of estrogen replacement therapy on response to tacrine in patients with Alzheimer's disease. Neurology 1996;46:1580-1584.
12. Sawada H, Ibi M, Kihara T, et al. Estradiol protects mesencephalic dopaminergic neurons from oxidative stress-induced neuronal death. Rapid Communication, J. Neurosci. Res 1998;54:707-719.
13. Woolly CS, McEwen BS. Estradiol regulates hippocampal dendritic spine density via an N-metyl-D-aspalate receptor-dependent mechanism. J. Neurosci 199414:7680-7687.
14. Farr SA, Banks WA, Morley JE. Estradiol potentiates acetylcholine and glutamate-mediated post-trial memory processing in the hippocampus. Brain Res 2000:864:263-269.
15. Foy MR, Xu J, Xie X, et al. 17beta-estradiol enhances NMDA receptor-mediated EPSPs and long-term potentiation. J Neurophysiol 1999;81:925-929.
16. Weiland NG. Estadiol selectively regulates agonists binding sites on the N-metyl-D- asparate receptor complex in the CA1 region of the hippocampus. Endocrinology 1992;131:662-668.
17. McNeill AM, Zhang C, Stanczyk FZ, et al. Estrogen increases endothelial nitric oxide synthase via estrogen receptors in rat cerebral blood vessels: Effect preserved after concurrent treatment with medroxyprogesterone acetate or progesterone. Stroke 200233:1685-1692.
18. Wit H, Schmitt L, Purdy R, et al. Effects of acute progesterone administration in healthy postmenopausal women and normally cycling women. Psychoneuroendocrinology 2001;26:697-710.
19. McAuley JW, Reynolds IJ, Kroboth FJ, et al. Orally administered progesterone enhances sensitivity to triazolam in postmenopausal women. J Clini Psychopharmacol 1995;15: 3-11.
20. Bitran D, Purdy RH, Kellogg CK. Anxiolytic effect of progesterone is associated with increases in cortical allopregnanolone and GABAA receptor function. Pharmacol Biochem Behav 1993;45:423-428.
21. Lambert JJ, Belelli D, Hill-Venning C, et al. Neurosteroids and GABAA receptor function. Trends Pharmacol Sci 1995;16:295-303.
22. Johansson I-M, Birzniece V, Lindblad C, et al. Allopregnanolone inhibits learning in the Morris water maze. Brain Res 2002;934:125-131.
23. 3H!norepinephrine release evoked by N-metyl-D-aspartate in the rat hippocampus. Proc Natl Acad Sci USA. 1995;92:3774-3778.
24. 1 receptor agonist properties, facilitates NMDA receptor-dependent learning in mice. European J Pharmaco 1997;328:9-18.
25. 1 receptor agonist SA4503 and neuroactive steroids on performance in a radial arm maze task in rats. neuropharmacology 2000;39:1617-1627.
26. Roof LR, Duvdrvani R, Braswell L, et al. Progesterone Facilitates Cognitive Recovery and Reduces Secondary Neuronal Loss Caused by Cortical Contusion Injury in Male Rats. Exp Neurol 1994;129:64-69.
27. Stein DG. Brain damage, sex hormones and recovery: a new role for progesterone and estrogen. Trend Neurosci 2001;24:386-391.
28. Ohkura T, Isse K, Akazawa K, et al. Evaluation of estrogen treatment in female patients with dementia of the Alzheimer type. Endocrinol Jpn 1994;41:361-371.
29. Schairer CJ, Troisi R, Sturgeon S, et al. Menopausal estrogen and estrogen-progestin replacement therapy and breast cancer risk. JAMA 2000;283:485-491.
30. Bimonte HA, Denenberg VH. Estradiol facilitates performance as working memory load increases. Pshychoneuroendocrinology 1999;24:161-173.
31. Gibbs RB. Effects of estrogen on basal forebrain cholinergic neurons vary as a function of dose and duration of treatment. Brain Res 1997;757:10-16.
32. Daniel JM, Roberts SL, Dohanich GP. Effects of ovarian hormones and environment on radial maze and water maze performance of female rats. Physiol Behav 1999;66:11-20.
33. Fader AJ, Johnson PE. M, Dohanich GP. Estrogen improves working but not reference memory and prevents amnestic effects of scopolamine on a radial-arm-maze. Pharmacol Biochem Behav 1999;62:711-717.
34. Gibbs RB. Estrogen replacement enhances acquisition of a spatial memory task and reduces deficits associated with hippocampal muscarinic receptor inhibition. Horm Behav 1999;36:222-33.
35. Gibbs RB. Long-term treatment with estrogen and progesterone enhances acquisition of spatial memory task by ovariectomized aged rats. Neurobiol Aging 2000;21:107-116.
36. Lydon RG, Nakajima S. Differential effects of scopolamine on working and reference memory depend upon level of training. Pharmacol Biochem Behav 1992;43:645-650.
37. Biggan SL, Ingles JL, Beninger RJ. Scopolamine differentially affects memory of 8- and 16-month-old rats in the double Y-Maze. Neurobiol Aging 1996;17:25-30.
38. Spangler EL, Chachich ME, Curtis NJ, et al. Age-related impairment in complex maze learning in rats: Relationship to neophobia and cholinergic antagonism. Neurobiol Aging 1989;10:133-141.
39. 1 muscarinic acetylcholine receptors activate extracellular signal-regulated kinase in CA1 pyramidal neurons in mouse hippocampal slices. Mol Cell Neurosci 2001;18:512-524.
40. El-Bakri NK, Adem A, Suliman IA, et al. Estrogen and progesterone treatment: effects in muscarinic M4 receptor subtype in the rat brain. Brain Res 2002;948:131-137.
41. Gibbs RB. Fluctuation in relative levels of choline acetyltransferase mRNA in different regions of the rat basal forebrain across the estrous cycle: effects of estrogen and progesterone. J Neuroscie 1996;16:1049-1055.
42. Woolly CS, McEwen BS. Roles of estradiol and progesterone in regulation of hippocampal dendric spine density during the estrus cycle in the rat. J Comp Neurol 1993;336:293-306.
43. Smith YR, Minoshima S, Kuhl DE, et al. Effects of long-term hormone therapy on cholinergic synaptic concentration in healthy postmenopausal women. J Clin Endocrinol Metabolism 2001;86:679-684.
44. Gibbs RB. Treatment with estrogen and progesterone affects relative levels of brain-derived neurotrophic factor mRNA and protein in different regions of the adult rat brain. Brain Res 1999;844:20-27.
45. 1) receptors. Brain Res 1998;799:64-77.
46. Al-Dahan MIM, Thomas PJ. Contrasting effects of testicularand ovarian steroids upon muscarinic binding sites in the brain. Pharmacol 1987;34:250-258.
47. Wilkinson M, Giles A, Wilkinson DA. M2 muscarinic ([3H]N-methyl scopolamine) binding in micropunches of rat venticular myocardium: characterization and modification by progesterone. Can. J physiol Pharmacol 1992;70:943-948.
48. Wilkinson M, Siauw M, Horackova M. Modulation of cardiac M2 muscarinic receptor binding by progesterone-related steroids. J Mol Cell Cardiol 1995;27:1831-1839.
49. Perriotti LI, Beck KD, Luine VN, et al. Progesterone and cocaine administration affect serotonin in the medial prefrontal cortex of ovariectomized rats. Neurosci Letters 2000;291:155-158.
50. Day JC, Piazza PV, Le Moal M, et al. Cocaine-induced increase in cortical acetylcholine relrease: Interaction with the hypothalamo-pituitary-adrenal axis. Eur J Neurosci 1997;9:1130-1136.
51. Ikemoto S, Goeders NE. Intra-medial prefrontal cortex injections of scopolamine increase instrumental responses for cocaine: An intravenous self-administration study in rats. Brain Rres Bulletin 2000;51:151-158.
52. Yabase M, Carino MA, Horita A. Cocaine produces cholinergically mediated analeptic and EEG arousal effects in rabbits and rats. Pharmacol Biochem Behav 1990;37:375-377.
53. Nilsen J, Brinton RD. Impact of progestines on estradiol potentiation of the glutamate calcium response. Neuroreport 2002;13:825-830.
54. Vongher JM, Frye A. Progesterone in conjunction with estradiol has neuroprotective effects in an animal model of neurodegeneration. Pharmacol Biochem Behav 1999;64:777-785.
55. Chen J, Chopp M, Li Y. Neuroprotective effects of progesterone after transient middle cerebral artery occlusion in rat. J Neurol Scie 1999;171:24-30.