Intra-medial prefrontal cortex injections of scopolamine increase instrumental responses for cocaine: An intravenous self-administration study in rats

Brain Research Bulletin

Volumn 51, Issue 2, 2000, Pages 151-158

  Ikemoto, Satoshi ^a   Goeders, Nick E ^a  

^a LOUISIANA STATE UNIV MEDICAL CENTER   (United States)

Author keywords

Locomotor activity; Mesocorticolimbic dopamine system; Nucleus accumbens; Reinforcement; Reward

Indexed keywords

CHOLINERGIC RECEPTOR; COCAINE; METHYLSCOPOLAMINE; MUSCARINIC RECEPTOR;

ANIMAL EXPERIMENT; ARTICLE; CHOLINERGIC RECEPTOR BLOCKING; CHOLINERGIC TRANSMISSION; CONTROLLED STUDY; DOPAMINERGIC SYSTEM; LOCOMOTION; MALE; NONHUMAN; NUCLEUS ACCUMBENS; PREFRONTAL CORTEX; PRIORITY JOURNAL; RAT; REINFORCEMENT; REWARD;

ANIMALS; COCAINE; COCAINE-RELATED DISORDERS; INJECTIONS, INTRAVENOUS; MALE; MOTOR ACTIVITY; MUSCARINIC ANTAGONISTS; NUCLEUS ACCUMBENS; PREFRONTAL CORTEX; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, MUSCARINIC; SCOPOLAMINE; SELF ADMINISTRATION;

EID: 0033955985     PISSN: 03619230     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0361-9230(99)00214-2     Document Type: Article

References (23)

1. Broersen L.M., Heinsbroek R.P.W., de Bruin J.P.C., Uylings H.B.M., Olivier B. The role of the medial prefrontal cortex of rats in short-term memory functioning Further support for involvement of cholinergic, rather than dopaminergic mechanisms . Brain Res. 674:1995;221-229.
2. Caine S.B., Koob G.F. Effects of mesolimbic dopamine depletion on responding maintained by cocaine and food. J. Exp. Anal. Behav. 61:1994;213-221.
3. Davis W.M., Smith S.G. Central cholinergic influence on self-administration of morphine and amphetamine. Life Sci. 16:1975;237-246.
4. Day J.C., Piazza P.V., Le Moal M., Maccari S. Cocaine-induced increase in cortical acetylcholine release Interaction with the hypothalamo-pituitary-adrenal axis . Eur. J. Neurosci. 9:1997;1130-1136.
5. de Belleroche J.S., Winn P., Murzi E., Williams S.F., Herberg L.J. Presynaptic modulation of dopamine-induced locomotor activity by oxotremorine in nucleus accumbens of the rat. J. Neural Trans. 54:1982;137-143.
6. Gaykema R.P., Luiten P.G., Nyakas C., Traber J. Cortical projection patterns of the medial septum-diagonal band complex. J. Comp. Neurol. 293:1990;103-124.
7. Glick S.D., Cox R.D. Dopaminergic and cholinergic influences on morphine self-administration in rats. Res. Comm. Chem. Pathol. Pharm. 12:1975;17-24.
8. Goeders N.E., Smith J.E. Cortical dopaminergic involvement in cocaine reinforcement. Science. 221:1983;773-775.
9. Goeders N.E., Smith J.E. Reinforcing properties of cocaine in the medial prefrontal cortex Primary action on presynaptic dopaminergic terminals . Pharm. Biochem. Behav. 25:1986;191-199.
10. Granon S., Poucet B., Thinus-Blanc C., Changeux J.P., Vidal C. Nicotinic and muscarinic receptors in the rat prefrontal cortex Differential roles in working memory, response selection and effortful processing . Psychopharmacology. 119:1995;139-144.
11. Heidbreder C.A., Shippenberg T.S. Evidence for an involvement of muscarinic cholinergic systems in the induction but not expression of behavioral sensitization to cocaine. Synapse. 24:1996;182-192.
12. Ikemoto S., Glazier B.S., Murphy J.M., McBride W.J. Rats self-administer carbachol directly into the nucleus accumbens. Physiol. Behav. 63:1998;811-814.
13. Jones D.L., Mogenson G.J., Wu M. Injections of dopaminergic, cholinergic, serotonergic and GABAergic drugs into the nucleus accumbens Effects on locomotor activity in the rat . Neuropharmacology. 20:1981;29-37.
14. Paxinos G., Watson C. The rat brain in stereotaxic coordinates. 3rd ed. 1997;Academic Press, San Diego.
15. Pettit H.O., Ettenberg A., Bloom F.E., Koob G.F. Destruction of dopamine in the nucleus accumbens selectively attenuates cocaine but not heroin self-administration in rats. Psychopharmacology. 84:1984;167-173.
16. Ragozzino M.E., Kesner R.P. The effects of muscarinic cholinergic receptor blockade in the rat anterior cingulate and prelimbic/infralimbic cortices on spatial working memory. Neurobiol. Learn. Mem. 69:1998;241-257.
17. Roberts D.C.S., Corcoran M.E., Fibiger H.C. On the role of ascending catecholaminergic systems in intravenous self-administration of cocaine. Pharmacol. Biochem. Behav. 6:1977;615-620.
18. Roberts D.C.S., Koob G.F., Klonoff P., Fibiger H.C. Extinction and recovery of cocaine self-administration following 6-hydroxydopamine lesions of the nucleus accumbens. Pharmacol. Biochem. Behav. 12:1980;781-787.
19. Robledo P., Weissenborn R., Robbins T.W., Everitt B.J. Effects of lesions of the nucleus basalis magnocellularis on the acquisition of cocaine self-administration in rats. Eur. J. Neurosci. 10:1998;1946-1955.
20. Satoh K., Fibiger H.C. Cholinergic neurons of the laterodorsal tegmental nucleus Efferent and afferent connections . J. Comp. Neurol. 253:1986;277-302.
21. Weissenborn R., Robbins T.W., Everitt B.J. Effects of medial prefrontal or anterior cingulate cortex lesions on responding for cocaine under fixed-ratio and second-order schedules of reinforcement in rats. Psychopharmacology. 134:1997;242-257.
22. Wilson J.M., Carroll M.E., Lac S.T., DiStefano L.M., Kish S.J. Choline acetyltransferase activity is reduced in rat nucleus accumbens after unlimited access to self-administration of cocaine. Neurosci. Lett. 180:1994;29-32.
23. Wilson M.C., Schuster C.R. Cholinergic influence on intravenous cocaine self-administration by Rhesus monkeys. Pharm. Biochem. Behav. 1:1973;643-649.