Heterologous expression of rat P450 2E1 in a mammalian cell line: in situ metabolism and cytotoxicity of N-nitrosodimethylamine

Carcinogenesis

Volumn 19, Issue 2, 1998, Pages 321-329

  Lin, Hsia Lien ^a   Roberts, Elizabeth S ^a   Hollenberg, Paul F ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 METHYLPYRAZOLE; 4 NITROPHENYLPHOSPHATASE; 7 ETHOXYCOUMARIN DEETHYLASE; ACETYLCYSTEINE; ALCOHOL; ASCORBIC ACID; BUTYLATED HYDROXYANISOLE; CELL PROTEIN; COMPLEMENTARY DNA; CRYSTAL VIOLET; CYTOCHROME P450; DIMETHYLNITROSAMINE; DIMETHYLNITROSAMINE DEMETHYLASE; DNA; GLUTATHIONE; ISONIAZID; N METHYL DEXTRO ASPARTIC ACID; RNA;

ARTICLE; CARCINOGENESIS; CELL METABOLISM; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DNA METHYLATION; DOSE RESPONSE; ENZYME ACTIVITY; EXPRESSION VECTOR; FIBROBLAST CULTURE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; LD 50; MONOLAYER CULTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN METHYLATION; RAT; RNA METHYLATION;

ANIMALS; ANTIOXIDANTS; BLOTTING, WESTERN; BUTHIONINE SULFOXIMINE; CELL LINE; CELL SURVIVAL; COUMARINS; CYTOCHROME P-450 CYP2E1; DINITROCHLOROBENZENE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; ETHANOL; FIBROBLASTS; GLUTATHIONE TRANSFERASE; HUMANS; INDICATORS AND REAGENTS; ISONIAZID; NITROGEN OXIDES; NITROPHENOLS; NITROSO COMPOUNDS; PYRAZOLES; RATS; SPIN LABELS; TIME FACTORS; TRANSFECTION;

EID: 0031947060     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/19.2.321     Document Type: Article

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