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Volumn 90, Issue 7, 2004, Pages 765-770

Effects of spironolactone on endothelial function, vascular angiotensin converting enzyme activity, and other prognostic markers in patients with mild heart failure already taking optimal treatment

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BRAIN NATRIURETIC PEPTIDE; DIPEPTIDYL CARBOXYPEPTIDASE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; PLACEBO; PROCOLLAGEN TYPE 3 AMINOPROPEPTIDE; SPIRONOLACTONE; WARFARIN;

EID: 3042693878     PISSN: 13556037     EISSN: None     Source Type: Journal    
DOI: 10.1136/hrt.2003.017368     Document Type: Article
Times cited : (127)

References (39)
  • 1
    • 0033517302 scopus 로고    scopus 로고
    • The effect of spironolactone on morbidity and mortality in patients with severe heart failure
    • Randomized aldactone evaluation study investigators
    • Pitt B, Zannad F, Remme WJ, et al. The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized aldactone evaluation study investigators. N Engl J Med 1999;341:709-17.
    • (1999) N Engl J Med , vol.341 , pp. 709-717
    • Pitt, B.1    Zannad, F.2    Remme, W.J.3
  • 2
    • 0037417252 scopus 로고    scopus 로고
    • Eplerenone, a selective aldosterone blocker, in patients with LV dysfunction after MI
    • Pitt B, Remme WJ, Zannad F, et al. Eplerenone, a selective aldosterone blocker, in patients with LV dysfunction after MI. N Engl J Med 2003;384:1309-21.
    • (2003) N Engl J Med , vol.384 , pp. 1309-1321
    • Pitt, B.1    Remme, W.J.2    Zannad, F.3
  • 3
    • 3042688314 scopus 로고    scopus 로고
    • Effect of aldosterone on the vascular bed: Introducing aldosterone induced vasculopathy
    • Braunwald E, ed. New York: McGraw Hill
    • Struthers AD. Effect of aldosterone on the vascular bed: introducing aldosterone induced vasculopathy. In Braunwald E, ed. Harrison's advances in cardiology. New York: McGraw Hill, 2003:12-7.
    • (2003) Harrison's Advances in Cardiology , pp. 12-17
    • Struthers, A.D.1
  • 4
    • 0034651798 scopus 로고    scopus 로고
    • Spironolactone increases nitric oxide bioactivity, improves endothelial vasodilator dysfunction, and suppresses vascular angiotensin I/angiotensin II conversion in patients with chronic heart failure
    • Farquharson CA, Struthers AD. Spironolactone increases nitric oxide bioactivity, improves endothelial vasodilator dysfunction, and suppresses vascular angiotensin I/angiotensin II conversion in patients with chronic heart failure. Circulation 2000;101:594-7.
    • (2000) Circulation , vol.101 , pp. 594-597
    • Farquharson, C.A.1    Struthers, A.D.2
  • 5
    • 0036796624 scopus 로고    scopus 로고
    • Aldosterone induces acute endothelial dysfunction in vivo in man: Evidence for an aldosterone induced vasculopathy
    • Farquharson C, Struthers AD. Aldosterone induces acute endothelial dysfunction in vivo in man: evidence for an aldosterone induced vasculopathy. Clin Sci 2002;103:425-31.
    • (2002) Clin Sci , vol.103 , pp. 425-431
    • Farquharson, C.1    Struthers, A.D.2
  • 6
    • 0037035471 scopus 로고    scopus 로고
    • Mineralocorticoid receptor antagonism in experimental atherosclerosis
    • Rajagopalan S, Duquaine D, King S, et al. Mineralocorticoid receptor antagonism in experimental atherosclerosis. Circulation 2002;105:2212-6.
    • (2002) Circulation , vol.105 , pp. 2212-2216
    • Rajagopalan, S.1    Duquaine, D.2    King, S.3
  • 7
    • 0031600240 scopus 로고    scopus 로고
    • Mineralocorticoid blockade reduces vascular injury in stroke prone hypertensive rats
    • Rocha R, Chander PHN, Khanna K, et al. Mineralocorticoid blockade reduces vascular injury in stroke prone hypertensive rats. Hypertension 1998;31:451-8.
    • (1998) Hypertension , vol.31 , pp. 451-458
    • Rocha, R.1    Chander, P.H.N.2    Khanna, K.3
  • 8
    • 0028860490 scopus 로고
    • Effects of adding spironolactone to an angiotensin-converting enzyme inhibitor in chronic congestive heart failure secondary to coronary artery disease
    • Barr CS, Lang CC, Hanson J, et al. Effects of adding spironolactone to an angiotensin-converting enzyme inhibitor in chronic congestive heart failure secondary to coronary artery disease. Am J Cardiol 1995;76:1259-65.
    • (1995) Am J Cardiol , vol.76 , pp. 1259-1265
    • Barr, C.S.1    Lang, C.C.2    Hanson, J.3
  • 9
    • 0032125642 scopus 로고    scopus 로고
    • Effects of spironolactone on exercise capacity and neurohormonal factors in patients with heart failure treated with loop diuretics and angiotensin-converting enzyme inhibitor
    • Kinugawa T, Ogino K, Kato M, et al. Effects of spironolactone on exercise capacity and neurohormonal factors in patients with heart failure treated with loop diuretics and angiotensin-converting enzyme inhibitor. Gen Pharmacol 1998;31:93-9.
    • (1998) Gen Pharmacol , vol.31 , pp. 93-99
    • Kinugawa, T.1    Ogino, K.2    Kato, M.3
  • 10
    • 0030870613 scopus 로고    scopus 로고
    • Aldosterone blockade reduces vascular collagen turnover, improves heart rate variability and reduces early morning rise in heart rate in heart failure patients
    • MacFadyen RJ, Barr CS, Struthers AD. Aldosterone blockade reduces vascular collagen turnover, improves heart rate variability and reduces early morning rise in heart rate in heart failure patients. Cardiovasc Res 1997;35:30-4.
    • (1997) Cardiovasc Res , vol.35 , pp. 30-34
    • MacFadyen, R.J.1    Barr, C.S.2    Struthers, A.D.3
  • 11
    • 0035312341 scopus 로고    scopus 로고
    • Effect of spironolactone on plasma brain natriuretic peptide and left ventricular remodeling in patients with congestive heart failure
    • Tsutamoto T, Wada A, Maeda K, et al. Effect of spironolactone on plasma brain natriuretic peptide and left ventricular remodeling in patients with congestive heart failure. J Am Coll Cardiol 2001;37:1228-33.
    • (2001) J Am Coll Cardiol , vol.37 , pp. 1228-1233
    • Tsutamoto, T.1    Wada, A.2    Maeda, K.3
  • 12
    • 0034727695 scopus 로고    scopus 로고
    • Limitation of excessive extracellular matrix turnover may contribute to survival benefit of spironolactone therapy in patients with congestive heart failure: Insights from the randomized aldactone evaluation study (RALES)
    • Zannad F, Alla F, Dousset B, on behalf of RALES Investigators, et al. Limitation of excessive extracellular matrix turnover may contribute to survival benefit of spironolactone therapy in patients with congestive heart failure: insights from the randomized aldactone evaluation study (RALES). Circulation 2000;102:2700-6.
    • (2000) Circulation , vol.102 , pp. 2700-2706
    • Zannad, F.1    Alla, F.2    Dousset, B.3
  • 13
    • 0037125404 scopus 로고    scopus 로고
    • Long-term, dose-dependent effects of spironolactone on left ventricular function and exercise tolerance in patients with chronic heart failure
    • Cicoira M, Zanolla L, Rossi A, et al. Long-term, dose-dependent effects of spironolactone on left ventricular function and exercise tolerance in patients with chronic heart failure. J Am Coll Cardiol 2002;40:304-10.
    • (2002) J Am Coll Cardiol , vol.40 , pp. 304-310
    • Cicoira, M.1    Zanolla, L.2    Rossi, A.3
  • 14
    • 0035370038 scopus 로고    scopus 로고
    • Circadian variation in the effects of aldosterone blockade on heart rate variability and QT dispersion in congestive heart failure
    • Yee KM, Pringle SD, Struthers AD. Circadian variation in the effects of aldosterone blockade on heart rate variability and QT dispersion in congestive heart failure. J Am Coll Cardiol 2001;37:1800-7.
    • (2001) J Am Coll Cardiol , vol.37 , pp. 1800-1807
    • Yee, K.M.1    Pringle, S.D.2    Struthers, A.D.3
  • 15
    • 0037047070 scopus 로고    scopus 로고
    • Allopurinol improves endothelial dysfunction in chronic heart failure
    • Farquharson C, Butler R, Hill A, et al. Allopurinol improves endothelial dysfunction in chronic heart failure. Circulation 2002;106:221-6.
    • (2002) Circulation , vol.106 , pp. 221-226
    • Farquharson, C.1    Butler, R.2    Hill, A.3
  • 16
    • 0037047080 scopus 로고    scopus 로고
    • Allopurinol and endothelial function in heart failure
    • Landmesser U, Drexler H. Allopurinol and endothelial function in heart failure. Circulation 2002;106:173-5.
    • (2002) Circulation , vol.106 , pp. 173-175
    • Landmesser, U.1    Drexler, H.2
  • 17
    • 0029030732 scopus 로고
    • Measuring forearm blood flow and interpreting the responses to drugs and mediators
    • Benjamin N, Calver A, Collier J, et al. Measuring forearm blood flow and interpreting the responses to drugs and mediators. Hypertension 1995;25:918-23.
    • (1995) Hypertension , vol.25 , pp. 918-923
    • Benjamin, N.1    Calver, A.2    Collier, J.3
  • 18
    • 0026003041 scopus 로고
    • Evaluation of the Reynolds Pathfinder II system for 24 h heart rate variability analysis
    • Molgaard H. Evaluation of the Reynolds Pathfinder II system for 24 h heart rate variability analysis. Eur Heart J 1991;12:1153-62.
    • (1991) Eur Heart J , vol.12 , pp. 1153-1162
    • Molgaard, H.1
  • 19
    • 0029928495 scopus 로고    scopus 로고
    • Heart rate variability: Standards of measurement, physiological interpretation and clinical use
    • Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology
    • Anon. Heart rate variability: standards of measurement, physiological interpretation and clinical use. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. Circulation 1996;93:1043-65.
    • (1996) Circulation , vol.93 , pp. 1043-1065
  • 20
    • 0027195028 scopus 로고
    • Validity of the Minnesota living with heart failure questionnaire as a measure of therapeutic response to enalapril or placebo
    • Rector TS, Kubo SH, Cohn JN. Validity of the Minnesota living with heart failure questionnaire as a measure of therapeutic response to enalapril or placebo. Am J Cardiol 1993;71:1106-7.
    • (1993) Am J Cardiol , vol.71 , pp. 1106-1107
    • Rector, T.S.1    Kubo, S.H.2    Cohn, J.N.3
  • 21
    • 0020527558 scopus 로고
    • The hospital anxiety and depression scale
    • Zigmond AS, Snaith RP. The hospital anxiety and depression scale. Acta Psychiatr Scand 1983;67:361-70.
    • (1983) Acta Psychiatr Scand , vol.67 , pp. 361-370
    • Zigmond, A.S.1    Snaith, R.P.2
  • 22
    • 0037007153 scopus 로고    scopus 로고
    • Risk stratification for postoperative cardiovascular events via noninvasive assessment of endothelial function: A prospective study
    • Gokce N, Keaney JF Jr, Hunter LM, et al. Risk stratification for postoperative cardiovascular events via noninvasive assessment of endothelial function: a prospective study. Circulation 2002;105:1567-72.
    • (2002) Circulation , vol.105 , pp. 1567-1572
    • Gokce, N.1    Keaney Jr., J.F.2    Hunter, L.M.3
  • 23
    • 0035960677 scopus 로고    scopus 로고
    • Endothelial dysfunction, oxidative stress, and risk of cardiovascular events in patients with coronary artery disease
    • Heitzer T, Schlinzig T, Krohn K, et al. Endothelial dysfunction, oxidative stress, and risk of cardiovascular events in patients with coronary artery disease. Circulation 2001;104:2673-8.
    • (2001) Circulation , vol.104 , pp. 2673-2678
    • Heitzer, T.1    Schlinzig, T.2    Krohn, K.3
  • 24
    • 0034047179 scopus 로고    scopus 로고
    • Late prognostic value of flow-mediated dilation in the brachial artery of patients with chest pain
    • Neunteufl T, Heher S, Katzenschlager R, et al. Late prognostic value of flow-mediated dilation in the brachial artery of patients with chest pain. Am J Cardiol 2000;86:207-10.
    • (2000) Am J Cardiol , vol.86 , pp. 207-210
    • Neunteufl, T.1    Heher, S.2    Katzenschlager, R.3
  • 25
    • 0035838416 scopus 로고    scopus 로고
    • Prognostic significance of endothelial dysfunction in hypertensive patients
    • Perticone F, Ceravolo R, Pujia A, et al. Prognostic significance of endothelial dysfunction in hypertensive patients. Circulation 2001;104:191-6.
    • (2001) Circulation , vol.104 , pp. 191-196
    • Perticone, F.1    Ceravolo, R.2    Pujia, A.3
  • 26
    • 0342424181 scopus 로고    scopus 로고
    • Prognostic impact of coronary vasodilator dysfunction on adverse long-term outcome of coronary heart disease
    • Schachinger V, Britten MB, Zeiher AM. Prognostic impact of coronary vasodilator dysfunction on adverse long-term outcome of coronary heart disease. Circulation 2000;10:1899-906.
    • (2000) Circulation , vol.10 , pp. 1899-1906
    • Schachinger, V.1    Britten, M.B.2    Zeiher, A.M.3
  • 27
    • 0001654669 scopus 로고    scopus 로고
    • Long-term follow-up of patients with mild coronary artery disease and endothelial dysfunction
    • Al Suwaidi J, Hamasaki S, Higano ST, et al. Long-term follow-up of patients with mild coronary artery disease and endothelial dysfunction. Circulation 2000;101:948-54.
    • (2000) Circulation , vol.101 , pp. 948-954
    • Al Suwaidi, J.1    Hamasaki, S.2    Higano, S.T.3
  • 28
    • 0037031266 scopus 로고    scopus 로고
    • Prognostic value of coronary vascular endothelial dysfunction
    • Halcox JPJ, Schenke WH, Zalos G, et al. Prognostic value of coronary vascular endothelial dysfunction. Circulation 2002;106:653-8.
    • (2002) Circulation , vol.106 , pp. 653-658
    • Halcox, J.P.J.1    Schenke, W.H.2    Zalos, G.3
  • 29
    • 0027997655 scopus 로고
    • Effect of ACE inhibitors on endothelium dependent peripheral vasodilatation in patients with chronic heart failure
    • Nakamura M, Funakoshi T, Arakawa N, et al. Effect of ACE inhibitors on endothelium dependent peripheral vasodilatation in patients with chronic heart failure. J Am Coll Cardiol 1994;24:1321-7.
    • (1994) J Am Coll Cardiol , vol.24 , pp. 1321-1327
    • Nakamura, M.1    Funakoshi, T.2    Arakawa, N.3
  • 30
    • 0037031310 scopus 로고    scopus 로고
    • Endothelial function: A barometer of cardiovascular risk
    • Vita JA, Keaney JF. Endothelial function: a barometer of cardiovascular risk. Circulation 2002;106:640-2.
    • (2002) Circulation , vol.106 , pp. 640-642
    • Vita, J.A.1    Keaney, J.F.2
  • 31
    • 0035838423 scopus 로고    scopus 로고
    • Aldosterone induces angiotensin-converting-enzyme gene expression in cultured neonatal rat cardiocytes
    • Harada E, Yoshimura M, Yasue H, et al. Aldosterone induces angiotensin-converting-enzyme gene expression in cultured neonatal rat cardiocytes. Circulation 2001;104:137-9.
    • (2001) Circulation , vol.104 , pp. 137-139
    • Harada, E.1    Yoshimura, M.2    Yasue, H.3
  • 32
    • 0027436742 scopus 로고
    • ACE and myocardial fibrosis in the rat receiving AII or aldosterone
    • Sun Y, Ratajska A, Zhou G, et al. ACE and myocardial fibrosis in the rat receiving AII or aldosterone. J Lab Clin Med 1993;122:395-403.
    • (1993) J Lab Clin Med , vol.122 , pp. 395-403
    • Sun, Y.1    Ratajska, A.2    Zhou, G.3
  • 33
    • 0032588244 scopus 로고    scopus 로고
    • 1 receptor sub-type as a cardiac target of aldosterone: Role in aldosterone salt induced fibrosis
    • 1 receptor sub-type as a cardiac target of aldosterone: role in aldosterone salt induced fibrosis. Hypertension 1999;33:981-6.
    • (1999) Hypertension , vol.33 , pp. 981-986
    • Robert, V.1    Heymes, C.2    Silvestre, J.S.3
  • 34
    • 0037028862 scopus 로고    scopus 로고
    • Gradual reactivation over time of vascular tissue angiotensin I to angiotensin II conversion during chronic lisinopril therapy in chronic heart failure
    • Forquharson CA, Struthers AD. Gradual reactivation over time of vascular tissue angiotensin I to angiotensin II conversion during chronic lisinopril therapy in chronic heart failure. J Am Coll Cardiol 2002;39:767-75.
    • (2002) J Am Coll Cardiol , vol.39 , pp. 767-775
    • Forquharson, C.A.1    Struthers, A.D.2
  • 35
    • 0034176934 scopus 로고    scopus 로고
    • Treatment of heart failure guided by plasma N-BNP levels improves outcome
    • Troughton RW, Frampton CM, Yandle TG, et al. Treatment of heart failure guided by plasma N-BNP levels improves outcome. Lancet 2000;355:1126-30.
    • (2000) Lancet , vol.355 , pp. 1126-1130
    • Troughton, R.W.1    Frampton, C.M.2    Yandle, T.G.3
  • 36
    • 0032785114 scopus 로고    scopus 로고
    • Plasma brain natriuretic peptide level as a biochemical marker of morbidity and mortality in patients with asymptomatic or minimally symptomatic left ventricular dysfunction: Comparison with plasma angiotensin II and endothelin-1
    • Tsutamoto T, Wada A, Maeda K, et al. Plasma brain natriuretic peptide level as a biochemical marker of morbidity and mortality in patients with asymptomatic or minimally symptomatic left ventricular dysfunction: comparison with plasma angiotensin II and endothelin-1. Eur Heart J 1999;20:1799-807.
    • (1999) Eur Heart J , vol.20 , pp. 1799-1807
    • Tsutamoto, T.1    Wada, A.2    Maeda, K.3
  • 37
    • 0037382430 scopus 로고    scopus 로고
    • Long QTc predicts future cardiac death in stroke survivors
    • Wong KYK, MacWalter RS, Douglas D, et al. Long QTc predicts future cardiac death in stroke survivors. Heart 2003;89:377-89.
    • (2003) Heart , vol.89 , pp. 377-389
    • Wong, K.Y.K.1    MacWalter, R.S.2    Douglas, D.3
  • 38
    • 0035870772 scopus 로고    scopus 로고
    • Life threatening hyperkalaemia during combined therapy with ACE inhibitors and spironolactone: An analysis of 25 cases
    • Schepkens H, Vanholder R, Billiouwv JM, et al. Life threatening hyperkalaemia during combined therapy with ACE inhibitors and spironolactone: an analysis of 25 cases. Am J Med 2001;110:438-41.
    • (2001) Am J Med , vol.110 , pp. 438-441
    • Schepkens, H.1    Vanholder, R.2    Billiouwv, J.M.3
  • 39
    • 0035315810 scopus 로고    scopus 로고
    • Serious adverse events experienced by patients with chronic heart failure taking spironolactone
    • Berry C, McMurray JJV. Serious adverse events experienced by patients with chronic heart failure taking spironolactone. Heart 2001;85:e8.
    • (2001) Heart , vol.85
    • Berry, C.1    McMurray, J.J.V.2


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