Aldosterone blockade reduces vascular collagen turnover, improves heart rate variability and reduces early morning rise in heart rate in heart failure patients

Cardiovascular Research

Volumn 35, Issue 1, 1997, Pages 30-34

  MacFadyen, Robert J ^a   Barr, Craig S ^a   Struthers, Allan D ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

ACE inhibitors; Aldosterone; Collagen; Diurnal variation; Heart failure; Heart rate; Human; Spironolactone; Sympathetic nervous system

Indexed keywords

ALDOSTERONE; COLLAGEN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; PROCOLLAGEN; SPIRONOLACTONE;

ADRENERGIC SYSTEM; ADULT; AGED; AMINO TERMINAL SEQUENCE; ARTICLE; AUTONOMIC DYSFUNCTION; AUTONOMIC NERVOUS SYSTEM; BRADYCARDIA; CIRCADIAN RHYTHM; CLINICAL ARTICLE; CLINICAL TRIAL; COLLAGEN METABOLISM; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FEMALE; HEART ARRHYTHMIA; HEART DEATH; HEART FAILURE; HEART MUSCLE FIBROSIS; HEART RATE; HEART RATE VARIABILITY; HUMAN; MALE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RR INTERVAL;

AGED; ALDOSTERONE ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; BIOLOGICAL MARKERS; CIRCADIAN RHYTHM; DIURETICS; DOUBLE-BLIND METHOD; DRUG THERAPY, COMBINATION; ELECTROCARDIOGRAPHY, AMBULATORY; FEMALE; FIBROSIS; HEART FAILURE, CONGESTIVE; HEART RATE; HUMANS; MALE; MYOCARDIUM; PEPTIDE FRAGMENTS; PROCOLLAGEN; SPIRONOLACTONE;

EID: 0030870613     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(97)00091-6     Document Type: Article

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