Effects of PACAP on neuronal damage and muscarinic receptor after global ischemia-reperfusion in old rat

Chinese Pharmacological Bulletin

Volumn 20, Issue 4, 2004, Pages 429-433

  Cui, Xu ^a   Han, Zhi Tao ^a   Liu, Xian Shuang ^a   Wang, Lu Ning ^a   Fang, Zheng Yu ^a   Li, Wen Bin ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

Apoptosis; Cerebral ischemia; Muscarine receptor; PACAP

Indexed keywords

EOSIN; HEMATOXYLIN; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; MUSCARINIC RECEPTOR; QUINUCLIDINYL BENZILATE;

ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; BINDING AFFINITY; BRAIN CORTEX; BRAIN INJURY; BRAIN ISCHEMIA; BRAIN LATERAL VENTRICLE; CONTROLLED STUDY; DISSOCIATION CONSTANT; HIPPOCAMPUS; NERVE INJURY; NEUROPROTECTION; NICK END LABELING; NONHUMAN; RAT; REPERFUSION INJURY;

EID: 3042675333     PISSN: 10011978     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Chung E, Iwasaki K, Mishima K et al. Repeated cerebral ischemia induced hippocampal cell death and impairments of spatial cognition in the rat. Life Sci 2002;72(4-5):609-19
2. Decker MW. The effects of aging on hippocampal and cortical projections of the forebrain cholinergic system. Brain Res, 1987;434(4):423-38
3. Uchida D, Arimura A, Somogyvari-Vigh A et al. Prevention of ischemia-induced death of hippocampal neurons by pituitary adenylate cyclase activating polypeptide. Brain Res, 1996;736(12):280-6
4. Reglodi D, Tamas A, Somogyvari-Vigh A et al. Effects of pretreatment with PACAP on the infarct size and functional outcome in rat permanent focal cerebral ischemia. Peptides, 2002; 23(12):2227-34
5. Pulsinelli WA, Brierley JB. A new model of bilateral hemispheric ischemia in the unanesthesized rat. Stroke, 1979;10 (3):267-72
6. Finkel T, Holbrook NJ. Oxidants, oxidative stress and biology of aging. Nature, 2000;408:239-47
7. Banks WA, Uchida D, Arimura A et al. Transport of pituitary adenylate cyclase-activating polypeptide across the blood-brain barrier and the prevention of ischemia-induced death of hippocampal neurons. Ann N Y Acad Sci, 1996;805:270-7
8. Onoue S, Endo K, Yajima T, Kashimoto K. Pituitary adenylate cyclase activating polypeptide regulates the basal production of nitric oxide in PC12 cells. Life Sci, 2002;71(2):205-14
9. Vaudry D, Pamantung TF, Basille M et al. PACAP protects cerebellar granule neurons against oxidative stress-induced apoptosis. Eur J Neurosci, 2002;15(9):1451-60
10. Shioda S, Ozawa H, Dohi K, Mizushima H. PACAP protects hippocampal neurons against apoptosis: Involvement of JNK/ SAPK signaling pathway. Ann N Y Acad Sci, 1998;865:111-7
11. Takei N, Torres E, Yuhara A et al. Pituitary adenylate cyclase-activating polypeptide promotes the survival of basal forebrain cholinergic neurons in vitro and in vivo comparion with effects of nerve growth factor. Eur J Neurosci, 2000;12(7): 2273-80
12. Masuo Y, Matsumoto Y, Tokito F et al. Effects of vasoactive intestinal polypeptide (VIP) and pituitary adenylate cyclase activating polypeptide (PACAP) on the spontaneous release of acetylcholine from the rat hippocampus by brain microdialysis. Brain Res, 1993;611(2):207-15
13. Roberto M, Brunelli M. PACAP-38 enhances excitatory synaptic transmission in the rat hippocampal CA, region. Learn Mem, 2000;7(5):303-11