메뉴 건너뛰기




Volumn 5, Issue 3, 2004, Pages 296-300

Antiepileptic drugs and reduced bone mineral density

Author keywords

Antiepileptic drugs; Bone mineral density; Bone turnover; Osteopenia; Osteoporosis

Indexed keywords

ALENDRONIC ACID; ANTICONVULSIVE AGENT; BISPHOSPHONIC ACID DERIVATIVE; CALCITONIN; CALCIUM; CARBAMAZEPINE; PARATHYROID HORMONE; PHENOBARBITAL; PHENYTOIN; PRIMIDONE; SELECTIVE ESTROGEN RECEPTOR MODULATOR; VALPROIC ACID; VITAMIN D;

EID: 3042663663     PISSN: 15255050     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yebeh.2004.02.005     Document Type: Review
Times cited : (62)

References (60)
  • 1
    • 0015492164 scopus 로고
    • Effect of chronic anticonvulsant therapy on serum 25-hydroxycalciferol levels in adults
    • Hahn T.J. Hendin B.A. Scharp C.R. Haddad J.G. Effect of chronic anticonvulsant therapy on serum 25-hydroxycalciferol levels in adults N. Engl. J. Med. 1972 900-904
    • (1972) N. Engl. J. Med. , pp. 900-904
    • Hahn, T.J.1    Hendin, B.A.2    Scharp, C.R.3    Haddad, J.G.4
  • 5
    • 0016662601 scopus 로고
    • Serum 25-hydroxycalciferol levels and bone mass in children on chronic anticonvulsant therapy
    • Hahn T.J. Hendin B.A. Scharp C.R. Boisseau V.C. Haddad J.G. Serum 25-hydroxycalciferol levels and bone mass in children on chronic anticonvulsant therapy N. Engl. J. Med. 292 1975 550-554
    • (1975) N. Engl. J. Med. , vol.292 , pp. 550-554
    • Hahn, T.J.1    Hendin, B.A.2    Scharp, C.R.3    Boisseau, V.C.4    Haddad, J.G.5
  • 9
    • 0034842745 scopus 로고    scopus 로고
    • Practice patterns of neurologists regarding bone and mineral effects of antiepileptic drug therapy
    • Valmadrid C. Voorhes C. Litt B. Schneyer C.R. Practice patterns of neurologists regarding bone and mineral effects of antiepileptic drug therapy Arch. Neurol. 58 2001 1369-1374
    • (2001) Arch. Neurol. , vol.58 , pp. 1369-1374
    • Valmadrid, C.1    Voorhes, C.2    Litt, B.3    Schneyer, C.R.4
  • 10
    • 0024537992 scopus 로고
    • Increased circulating levels of gamma-carboxyglutamic acid-containing protein and decreased bone mass in children on anticonvulsant therapy
    • Takeshita N. Seino Y. Ishida H. et al. Increased circulating levels of gamma-carboxyglutamic acid-containing protein and decreased bone mass in children on anticonvulsant therapy Calcif. Tissue Int. 44 1989 80-85
    • (1989) Calcif. Tissue Int. , vol.44 , pp. 80-85
    • Takeshita, N.1    Seino, Y.2    Ishida, H.3
  • 11
    • 0034027502 scopus 로고    scopus 로고
    • Changes in bone turnover and deoxypryidinoline levels in epileptic patients
    • Telci A. Cakatay U. Kurt B.B. et al. Changes in bone turnover and deoxypryidinoline levels in epileptic patients Clin. Chem. Lab. Med. 38 2000 47-50
    • (2000) Clin. Chem. Lab. Med. , vol.38 , pp. 47-50
    • Telci, A.1    Cakatay, U.2    Kurt, B.B.3
  • 12
    • 0023875297 scopus 로고
    • Effects of anticonvulsant drug therapy on bone mineral density in a pediatric population
    • Timperlake R.W. Cook S.D. Thomas K.A. et al. Effects of anticonvulsant drug therapy on bone mineral density in a pediatric population J. Pediat. Orthop. 8 1988 467-470
    • (1988) J. Pediat. Orthop. , vol.8 , pp. 467-470
    • Timperlake, R.W.1    Cook, S.D.2    Thomas, K.A.3
  • 13
    • 0028292967 scopus 로고
    • Bone mineral density measured by dual energy X-ray absorptiometry and novel markers of bone formation and resorption in patients on antiepileptic drugs
    • Valimaki M. Tiihonen M. Latinen K. et al. Bone mineral density measured by dual energy X-ray absorptiometry and novel markers of bone formation and resorption in patients on antiepileptic drugs J. Bone Miner. Res. 9 1994 631-637
    • (1994) J. Bone Miner. Res. , vol.9 , pp. 631-637
    • Valimaki, M.1    Tiihonen, M.2    Latinen, K.3
  • 14
    • 0033002623 scopus 로고    scopus 로고
    • Bone mineral density of epileptic patients on long term antiepileptic therapy: A quantitative digital radiographic study
    • Kubota F. Kifune A. Shibata N. et al. Bone mineral density of epileptic patients on long term antiepileptic therapy: a quantitative digital radiographic study Epilepsy Res. 33 1999 93-97
    • (1999) Epilepsy Res. , vol.33 , pp. 93-97
    • Kubota, F.1    Kifune, A.2    Shibata, N.3
  • 15
    • 0018853236 scopus 로고
    • Bone mineral status measured by direct photon absorptiometry in institutionalized adults receiving long-term anticonvulsant therapy and multivitamin supplementation
    • Barden H.S. Mazess R.B. Rose P.G. McAweeney W. Bone mineral status measured by direct photon absorptiometry in institutionalized adults receiving long-term anticonvulsant therapy and multivitamin supplementation Calcif. Tissue Int. 31 1980 117-121
    • (1980) Calcif. Tissue Int. , vol.31 , pp. 117-121
    • Barden, H.S.1    Mazess, R.B.2    Rose, P.G.3    McAweeney, W.4
  • 16
    • 0025333653 scopus 로고
    • Vitamin D status of ambulatory and nonambulatory mentally retarded children with and without carbamazepine treatment
    • Lamberg-Allardt C. Wilska M. Saraster K.L. Gronlund T. Vitamin D status of ambulatory and nonambulatory mentally retarded children with and without carbamazepine treatment Ann. Nutr. Metab. 34 1990 216-220
    • (1990) Ann. Nutr. Metab. , vol.34 , pp. 216-220
    • Lamberg-Allardt, C.1    Wilska, M.2    Saraster, K.L.3    Gronlund, T.4
  • 17
    • 0016731057 scopus 로고
    • The effect of anticonvulsant therapy on serum levels of 25-hydroxyvitamin D, calcium and parathyroid hormone
    • Bouillon R. Reynaert J. Claes J.H. Lissens W. DeMoor P. The effect of anticonvulsant therapy on serum levels of 25-hydroxyvitamin D, calcium and parathyroid hormone J. Clin. Endocrinol. Metab. 41 1975 1130-1135
    • (1975) J. Clin. Endocrinol. Metab. , vol.41 , pp. 1130-1135
    • Bouillon, R.1    Reynaert, J.2    Claes, J.H.3    Lissens, W.4    DeMoor, P.5
  • 18
    • 0022515632 scopus 로고
    • A comparative study of the relative influence of different anticonvulsant drugs, UV exposure and diet on vitamin D and calcium metabolism in outpatients with epilepsy
    • Gough H. Goggin G. Bissessar A. Baker M. Crowley M. Callaghan N. A comparative study of the relative influence of different anticonvulsant drugs, UV exposure and diet on vitamin D and calcium metabolism in outpatients with epilepsy Q. J. Med. 230 1986 569-577
    • (1986) Q. J. Med. , vol.230 , pp. 569-577
    • Gough, H.1    Goggin, G.2    Bissessar, A.3    Baker, M.4    Crowley, M.5    Callaghan, N.6
  • 19
    • 0034794545 scopus 로고    scopus 로고
    • Long term valproate and lamotrigine treatment may be a marker for reduced growth and bone mass in children with epilepsy
    • Guo C.Y. Ronen G. Atkinson S. Long term valproate and lamotrigine treatment may be a marker for reduced growth and bone mass in children with epilepsy Epilepsia 42 2001 1141-1147
    • (2001) Epilepsia , vol.42 , pp. 1141-1147
    • Guo, C.Y.1    Ronen, G.2    Atkinson, S.3
  • 20
    • 0015752461 scopus 로고
    • Incidence of anticonvulsant osteomalacia and effect of vitamin D: Controlled therapeutic trial
    • Christiansen C. Rodbro P. Lund M. Incidence of anticonvulsant osteomalacia and effect of vitamin D: controlled therapeutic trial Br. Med. J. 4 1973 695-701
    • (1973) Br. Med. J. , vol.4 , pp. 695-701
    • Christiansen, C.1    Rodbro, P.2    Lund, M.3
  • 21
    • 0019980298 scopus 로고
    • Serum vitamin D metabolites in epileptic patients treated with 2 different anti-convulsants
    • Tjellesen L. Christiansen C. Serum vitamin D metabolites in epileptic patients treated with 2 different anti-convulsants Acta Neurol. Scand. 66 1982 335-341
    • (1982) Acta Neurol. Scand , vol.66 , pp. 335-341
    • Tjellesen, L.1    Christiansen, C.2
  • 22
    • 0020514188 scopus 로고
    • Does carbamazepine cause disturbances in calcium metabolism in epileptic patients?
    • Tjellesen L. Nilas L. Christiansen C. Does carbamazepine cause disturbances in calcium metabolism in epileptic patients? Acta Neurol. Scand. 68 1983 13-19
    • (1983) Acta Neurol. Scand , vol.68 , pp. 13-19
    • Tjellesen, L.1    Nilas, L.2    Christiansen, C.3
  • 23
    • 0015466657 scopus 로고
    • Influence of diphenylhydantoin and phenobarbital on intestinal calcium transport in the rat
    • Koch H.C. Kraft D. von Herrath D. Influence of diphenylhydantoin and phenobarbital on intestinal calcium transport in the rat Epilepsia 13 1972 829-841
    • (1972) Epilepsia , vol.13 , pp. 829-841
    • Koch, H.C.1    Kraft, D.2    von Herrath, D.3
  • 24
    • 0021238171 scopus 로고
    • Decreased serum ionized calcium and normal vitamin D metabolite levels in patients with anticonvulsant drug treatment
    • Weinstein R. Bryce G. Sappington L.J. King D.W. Gallagher B.B. Decreased serum ionized calcium and normal vitamin D metabolite levels in patients with anticonvulsant drug treatment J. Clin. Endocrinol. Metab. 58 1984 1003-1009
    • (1984) J. Clin. Endocrinol. Metab. , vol.58 , pp. 1003-1009
    • Weinstein, R.1    Bryce, G.2    Sappington, L.J.3    King, D.W.4    Gallagher, B.B.5
  • 25
    • 0020067475 scopus 로고
    • Decreased serum 24, 25-dihydroxyvitamin D concentration during long-term anticonvulsant therapy in adult epileptics
    • Zerwekh J. Homan R. Tindall R. Pak C.Y. Decreased serum 24, 25-dihydroxyvitamin D concentration during long-term anticonvulsant therapy in adult epileptics Ann. Neurol. 12 1982 184-186
    • (1982) Ann. Neurol. , vol.12 , pp. 184-186
    • Zerwekh, J.1    Homan, R.2    Tindall, R.3    Pak, C.Y.4
  • 26
    • 0002959924 scopus 로고
    • Dynamic differences in trabecular bone remodeling between patients after jejuno-ileal bypass for obesity and epileptic patients receiving anticonvulsant therapy
    • Mosedike L. Melsen F. Dynamic differences in trabecular bone remodeling between patients after jejuno-ileal bypass for obesity and epileptic patients receiving anticonvulsant therapy Metab. Bone Dis. Relat. Res. 2 1980 77-82
    • (1980) Metab. Bone Dis. Relat. Res. , vol.2 , pp. 77-82
    • Mosedike, L.1    Melsen, F.2
  • 30
    • 0015699938 scopus 로고
    • Vitamin D-dependent rickets in institutionalized, mentally retarded children receiving long-term anticonvulsant therapy: I. A survey of 288 patients
    • Lifshitz F. Maclaren N.K. Vitamin D-dependent rickets in institutionalized, mentally retarded children receiving long-term anticonvulsant therapy: I. A survey of 288 patients J. Pediatr. 83 1973 612-620
    • (1973) J. Pediatr. , vol.83 , pp. 612-620
    • Lifshitz, F.1    Maclaren, N.K.2
  • 31
    • 0034008836 scopus 로고    scopus 로고
    • Increased bone turnover in epileptic patients treated with carbamazepine
    • Verotti A. Greco R. Morgese G. Chiarelli F. Increased bone turnover in epileptic patients treated with carbamazepine Ann. Neurol. 47 2000 385-388
    • (2000) Ann. Neurol. , vol.47 , pp. 385-388
    • Verotti, A.1    Greco, R.2    Morgese, G.3    Chiarelli, F.4
  • 32
    • 0034097478 scopus 로고    scopus 로고
    • Long-term anticonvulsant therapy leads to low bone mineral density: Evidence for direct drug effects of phenytoin and carbamazepine on human osteoblast-like cells
    • Feldkamp J. Becker A. Wilte O.W. Scharff D. Scherbaum W.A. Long-term anticonvulsant therapy leads to low bone mineral density: evidence for direct drug effects of phenytoin and carbamazepine on human osteoblast-like cells Exp. Clin. Endocrinol. Diabetes 108 2000 37-43
    • (2000) Exp. Clin. Endocrinol. Diabetes , vol.108 , pp. 37-43
    • Feldkamp, J.1    Becker, A.2    Wilte, O.W.3    Scharff, D.4    Scherbaum, W.A.5
  • 33
    • 0018139085 scopus 로고
    • Interaction of diphenylhydantoin and phenobarbital with hormonal mediation of fetal rat bone resorption in vitro
    • Hahn T.J. Scharp C.R. Richardson C.A. Halstead L.R. Kahn A.J. Teitelbaum S.L. Interaction of diphenylhydantoin and phenobarbital with hormonal mediation of fetal rat bone resorption in vitro J. Clin. Invest. 62 1978 406-414
    • (1978) J. Clin. Invest. , vol.62 , pp. 406-414
    • Hahn, T.J.1    Scharp, C.R.2    Richardson, C.A.3    Halstead, L.R.4    Kahn, A.J.5    Teitelbaum, S.L.6
  • 34
    • 0032882451 scopus 로고    scopus 로고
    • Bone density and antiepileptic drugs: A case controlled study
    • Stephen L.J. McLellan A.R. Harrison J.H. et al. Bone density and antiepileptic drugs: a case controlled study Seizure 8 1999 339-342
    • (1999) Seizure , vol.8 , pp. 339-342
    • Stephen, L.J.1    McLellan, A.R.2    Harrison, J.H.3
  • 35
    • 0029088857 scopus 로고
    • Effect of carbamazepine and valproate on bone mineral density
    • Sheth R. Wesolewski C.A. Jacob J.C. et al. Effect of carbamazepine and valproate on bone mineral density J. Pediatr. 127 1995 256-262
    • (1995) J. Pediatr. , vol.127 , pp. 256-262
    • Sheth, R.1    Wesolewski, C.A.2    Jacob, J.C.3
  • 36
    • 0031691046 scopus 로고    scopus 로고
    • Evaluation of bone mineral density in children receiving antiepileptic drugs
    • Akin R. Okutan V. Sarici U. Evaluation of bone mineral density in children receiving antiepileptic drugs Pediatr. Neurol. 19 1998 129-131
    • (1998) Pediatr. Neurol. , vol.19 , pp. 129-131
    • Akin, R.1    Okutan, V.2    Sarici, U.3
  • 37
    • 0030944719 scopus 로고    scopus 로고
    • Bone status after long-term anticonvulsant therapy in epileptic patients: Evaluation using quantitative ultrasound of calcaneus and phalanges
    • Pluskiewicz W. Nowakowska J. Bone status after long-term anticonvulsant therapy in epileptic patients: evaluation using quantitative ultrasound of calcaneus and phalanges Ultrasound Med. Biol. 23 1997 553-558
    • (1997) Ultrasound Med. Biol. , vol.23 , pp. 553-558
    • Pluskiewicz, W.1    Nowakowska, J.2
  • 38
    • 0028153198 scopus 로고
    • Effects of anti-epileptic drug therapy on bone mineral density in ambulatory epileptic children
    • Chung S. Ahn C. Effects of anti-epileptic drug therapy on bone mineral density in ambulatory epileptic children Brain Dev. 16 1994 382-385
    • (1994) Brain Dev. , vol.16 , pp. 382-385
    • Chung, S.1    Ahn, C.2
  • 42
    • 0026011883 scopus 로고
    • A prospective study to evaluate the dose of vitamin D required to correct low 25-hydroxyvitamin D levels, calcium, and alkaline phosphatase in patients at risk of developing antiepileptic drug induced osteomalacia
    • Collins N. Maher J. Cole M. Baker M. Callaghan N. A prospective study to evaluate the dose of vitamin D required to correct low 25-hydroxyvitamin D levels, calcium, and alkaline phosphatase in patients at risk of developing antiepileptic drug induced osteomalacia Q. J. Med. 286 1991 113-122
    • (1991) Q. J. Med. , vol.286 , pp. 113-122
    • Collins, N.1    Maher, J.2    Cole, M.3    Baker, M.4    Callaghan, N.5
  • 44
    • 0034075103 scopus 로고    scopus 로고
    • Effect of vitamin D and calcium on bone mineral density in children with CP and epilepsy in full time care
    • Jekovec-Vrhosek M. Kocijancic A. Prezelj J. Effect of vitamin D and calcium on bone mineral density in children with CP and epilepsy in full time care Dev. Med. Child Neurol. 42 2000 403-405
    • (2000) Dev. Med. Child Neurol. , vol.42 , pp. 403-405
    • Jekovec-Vrhosek, M.1    Kocijancic, A.2    Prezelj, J.3
  • 45
    • 0019455573 scopus 로고
    • Factors causing rickets in institutionalized handicapped children on anticonvulsant therapy
    • Morijiri Y. Sato J. Factors causing rickets in institutionalized handicapped children on anticonvulsant therapy Arch. Dis. Child 56 1981 446-449
    • (1981) Arch. Dis. Child , vol.56 , pp. 446-449
    • Morijiri, Y.1    Sato, J.2
  • 46
    • 0016432937 scopus 로고
    • Effects of anticonvulsants and inactivity on bone disease in epileptics
    • Murchison L.E. Bewsher P.D. Chesters M. et al. Effects of anticonvulsants and inactivity on bone disease in epileptics Postgrad. Med. J. 51 1975 18-21
    • (1975) Postgrad. Med. J. , vol.51 , pp. 18-21
    • Murchison, L.E.1    Bewsher, P.D.2    Chesters, M.3
  • 47
    • 0016528063 scopus 로고
    • Osteomalacia associated with anticonvulsant drug therapy in mentally retarded children
    • Tolman K.G. Jubiz W. Sannella J.J. et al. Osteomalacia associated with anticonvulsant drug therapy in mentally retarded children Pediatrics 56 1975 45-51
    • (1975) Pediatrics , vol.56 , pp. 45-51
    • Tolman, K.G.1    Jubiz, W.2    Sannella, J.J.3
  • 49
    • 0021080595 scopus 로고
    • Low plasma 25-hydroxyvitamin D and serum calcium levels in institutionalized epileptic subjects: Associated risk factors, consequences and response to treatment with vitamin D
    • Davie M.W. Emberson C.E. Lawson D.E. et al. Low plasma 25-hydroxyvitamin D and serum calcium levels in institutionalized epileptic subjects: associated risk factors, consequences and response to treatment with vitamin D Q. J. Med. 205 1983 79-91
    • (1983) Q. J. Med. , vol.205 , pp. 79-91
    • Davie, M.W.1    Emberson, C.E.2    Lawson, D.E.3
  • 50
    • 0023025983 scopus 로고
    • Long term anticonvulsant therapy and vitamin D metabolism in ambulatory pubertal children
    • Ala-Houhala M. Korpela R. Koivikko M. Long term anticonvulsant therapy and vitamin D metabolism in ambulatory pubertal children Neuropediatrics 17 1986 212-216
    • (1986) Neuropediatrics , vol.17 , pp. 212-216
    • Ala-Houhala, M.1    Korpela, R.2    Koivikko, M.3
  • 52
  • 53
    • 0015789957 scopus 로고
    • Anticonvulsant drugs and vitamin D metabolism
    • Livingston S. Berman W. Pauli L. Anticonvulsant drugs and vitamin D metabolism JAMA 224 1973 1034-1035
    • (1973) JAMA , vol.224 , pp. 1034-1035
    • Livingston, S.1    Berman, W.2    Pauli, L.3
  • 54
    • 0035859862 scopus 로고    scopus 로고
    • Decreased bone mass and increased bone turnover with valproate therapy in adults with epilepsy
    • Sato Y. Kondo I. Ishida S. et al. Decreased bone mass and increased bone turnover with valproate therapy in adults with epilepsy Neurology 57 2001 445-449
    • (2001) Neurology , vol.57 , pp. 445-449
    • Sato, Y.1    Kondo, I.2    Ishida, S.3
  • 55
    • 0036094249 scopus 로고    scopus 로고
    • Antiepileptic drug-induced bone loss in young male patients who have seizures
    • Andresss D.L. Ozuna J. Tirschwell D. et al. Antiepileptic drug-induced bone loss in young male patients who have seizures Arch. Neurol. 59 2002 781-786
    • (2002) Arch. Neurol. , vol.59 , pp. 781-786
    • Andresss, D.L.1    Ozuna, J.2    Tirschwell, D.3
  • 56
    • 0030940090 scopus 로고    scopus 로고
    • Vitamin D, calcium, and bone status in children with developmental delay in relation to anticonvulsant use and ambulatory status
    • Baer M. Kozlowski B. Blyler E.M. Trahms C.M. Taylor M.L. Hogan M.P. Vitamin D, calcium, and bone status in children with developmental delay in relation to anticonvulsant use and ambulatory status Am. J. Clin. Nutr. 65 1997 1042-1051
    • (1997) Am. J. Clin. Nutr. , vol.65 , pp. 1042-1051
    • Baer, M.1    Kozlowski, B.2    Blyler, E.M.3    Trahms, C.M.4    Taylor, M.L.5    Hogan, M.P.6
  • 58
    • 1642566070 scopus 로고    scopus 로고
    • Treatment of anticonvulsant drug-induced bone disease
    • Drezner M.K. Treatment of anticonvulsant drug-induced bone disease Epilepsy Behav. 5 Suppl 2 2004 41-47
    • (2004) Epilepsy Behav. , vol.5 , Issue.SUPPL. 2 , pp. 41-47
    • Drezner, M.K.1
  • 59
    • 1642484485 scopus 로고    scopus 로고
    • Epilepsy and bone health in adults
    • Pack A. Morrell M.J. Epilepsy and bone health in adults Epilepsy Behav. 5 Suppl 2 2004 24-29
    • (2004) Epilepsy Behav. , vol.5 , Issue.SUPPL. 2 , pp. 24-29
    • Pack, A.1    Morrell, M.J.2
  • 60
    • 1642566108 scopus 로고    scopus 로고
    • Pathophysiology of bone loss in patients receiving anticonvulsant therapy
    • Fitzpatrick L.A. Pathophysiology of bone loss in patients receiving anticonvulsant therapy Epilepsy Behav. 5 Suppl 2 2004 3-15
    • (2004) Epilepsy Behav. , vol.5 , Issue.SUPPL. 2 , pp. 3-15
    • Fitzpatrick, L.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.