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Volumn 47, Issue 2, 2004, Pages 102-107

A comparison of the exponential decay slope between PEG-IFN alfa-2b/ribavirin and IFN alfa-2b/ribavirin combination therapy in patients with chronic hepatitis C genotype 1b infection and a high viral load

Author keywords

Chronic hepatitis C; Genotype 1; HCV dynamics; PEG interferon; Ribavirin

Indexed keywords

PEGINTERFERON ALPHA2B; RECOMBINANT ALPHA2B INTERFERON; RIBAVIRIN;

EID: 3042636460     PISSN: 03005526     EISSN: None     Source Type: Journal    
DOI: 10.1159/000077833     Document Type: Article
Times cited : (14)

References (23)
  • 1
    • 0031567749 scopus 로고    scopus 로고
    • Hepatitis C: Global prevalence
    • 1WHO: Hepatitis C: Global prevalence. Wkly Epidemiol Rec 1997;72:341-344.
    • (1997) Wkly Epidemiol Rec , vol.72 , pp. 341-344
  • 2
    • 0030933395 scopus 로고    scopus 로고
    • Natural history of liver fibrosis progression in patients with chronic hepatitis C
    • The OBSVIRC, METAVIR, CLINIVIR, and DOSVIRC groups
    • Poynard T, Bedossa P, Opolon P: Natural history of liver fibrosis progression in patients with chronic hepatitis C. The OBSVIRC, METAVIR, CLINIVIR, and DOSVIRC groups. Lancet 1997;349:825-832.
    • (1997) Lancet , vol.349 , pp. 825-832
    • Poynard, T.1    Bedossa, P.2    Opolon, P.3
  • 7
    • 0035934568 scopus 로고    scopus 로고
    • Peginterferon alfa-2b in combination with ribabirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C. Results of a randomized trial
    • Manns MP, McHutchison JG, Gordon SC, Rustgi VK, Shiffman M, Reindollar R, Goodman ZD, Koury K, Ling M, Albrecht JK: Peginterferon alfa-2b in combination with ribabirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C. Results of a randomized trial. Lancet 2001;35:958-965.
    • (2001) Lancet , vol.35 , pp. 958-965
    • Manns, M.P.1    McHutchison, J.G.2    Gordon, S.C.3    Rustgi, V.K.4    Shiffman, M.5    Reindollar, R.6    Goodman, Z.D.7    Koury, K.8    Ling, M.9    Albrecht, J.K.10
  • 8
    • 0036240477 scopus 로고    scopus 로고
    • Mechanism of action of ribavirin in the combination treatment of chronic HCV infection
    • Lau JYN, Tam RC, Liand TJ, Hong Z: Mechanism of action of ribavirin in the combination treatment of chronic HCV infection. Hepatology 2002;35:1002-1009.
    • (2002) Hepatology , vol.35 , pp. 1002-1009
    • Lau, J.Y.N.1    Tam, R.C.2    Liand, T.J.3    Hong, Z.4
  • 9
    • 0033806292 scopus 로고    scopus 로고
    • Population pharmacokinetics and phamacodynamic analysis of ribavirin in patients with chronic hepatitis C
    • Jen JF, Glue P, Gupta S: Population pharmacokinetics and phamacodynamic analysis of ribavirin in patients with chronic hepatitis C. Ther Drug Monit 2000;22:555-565.
    • (2000) Ther Drug Monit , vol.22 , pp. 555-565
    • Jen, J.F.1    Glue, P.2    Gupta, S.3
  • 10
    • 0032475822 scopus 로고    scopus 로고
    • Hepatitis C viral dynamics in vivo and the antiviral efficacy on interferon-alpha therapy
    • Neumann AU, Lam NP, Dahari H: Hepatitis C viral dynamics in vivo and the antiviral efficacy on interferon-alpha therapy. Science 1998;282:1167-1169.
    • (1998) Science , vol.282 , pp. 1167-1169
    • Neumann, A.U.1    Lam, N.P.2    Dahari, H.3
  • 12
    • 17844396894 scopus 로고    scopus 로고
    • A potent antiviral effect on hepatitis C viral dynamics in serum and peripheral blood mononuclear cells during combination therapy with high-dose daily interferon alfa plus ribavirin and intravenous twice-daily treatment with interferon beta
    • Asahina Y, Izumi N, Uchihara M, Noguchi O, Tsuchiya K, Hamano K, Itakura J, Miyake S, Sakai T: A potent antiviral effect on hepatitis C viral dynamics in serum and peripheral blood mononuclear cells during combination therapy with high-dose daily interferon alfa plus ribavirin and intravenous twice-daily treatment with interferon beta. Hepatology 2001;34:377-384.
    • (2001) Hepatology , vol.34 , pp. 377-384
    • Asahina, Y.1    Izumi, N.2    Uchihara, M.3    Noguchi, O.4    Tsuchiya, K.5    Hamano, K.6    Itakura, J.7    Miyake, S.8    Sakai, T.9
  • 14
    • 18344375635 scopus 로고    scopus 로고
    • Viral dynamics and pharmacokinetics in combined interferon alfa-2b and ribavirin therapy for patients infected with hepatitis C virus genotype 1b and high pretreatment viral load
    • Tsubota A, Akuta N, Suzuki F, Suzuki Y, Someya T, Kobayashi M, Arase Y, Saitoh S, Ikeda K, Kumada H: Viral dynamics and pharmacokinetics in combined interferon alfa-2b and ribavirin therapy for patients infected with hepatitis C virus genotype 1b and high pretreatment viral load. Intervirology 2002;45:33-42.
    • (2002) Intervirology , vol.45 , pp. 33-42
    • Tsubota, A.1    Akuta, N.2    Suzuki, F.3    Suzuki, Y.4    Someya, T.5    Kobayashi, M.6    Arase, Y.7    Saitoh, S.8    Ikeda, K.9    Kumada, H.10
  • 16
    • 0030039045 scopus 로고    scopus 로고
    • Effect of interferon alfa on the dynamics of hepatitis C virus turnover in vivo
    • Zeuzem S, Schmidt JM, Lee JH, Ruster B, Roth WK: Effect of interferon alfa on the dynamics of hepatitis C virus turnover in vivo. Hepatology 1996;23:366-371.
    • (1996) Hepatology , vol.23 , pp. 366-371
    • Zeuzem, S.1    Schmidt, J.M.2    Lee, J.H.3    Ruster, B.4    Roth, W.K.5
  • 18
    • 0032055507 scopus 로고    scopus 로고
    • Ribavirin inhibits viral-induced macrophage production of TNF, IL-1, the procoagulant fgl2 prothrombinase and preserves Th1 cytokine production but inhibits Th2 cytokine response
    • Ning Q, Brown D, Parodo J, Cattral M, Gorczynski R, Cole E, Fung L, Ding JW, Liu MF, Rotstein O, Phillips MJ, Levy G: Ribavirin inhibits viral-induced macrophage production of TNF, IL-1, the procoagulant fgl2 prothrombinase and preserves Th1 cytokine production but inhibits Th2 cytokine response. J Immunol 1998;160:3487-3493.
    • (1998) J Immunol , vol.160 , pp. 3487-3493
    • Ning, Q.1    Brown, D.2    Parodo, J.3    Cattral, M.4    Gorczynski, R.5    Cole, E.6    Fung, L.7    Ding, J.W.8    Liu, M.F.9    Rotstein, O.10    Phillips, M.J.11    Levy, G.12
  • 20
    • 0010693314 scopus 로고    scopus 로고
    • Effects of the ribavirin-interferon alpha combination on cultured peripheral blood mononuclear cells from chronic hepatitis C patients
    • Martin J, Navas S, Quiroga JA, Pardo M, Carreno V: Effects of the ribavirin-interferon alpha combination on cultured peripheral blood mononuclear cells from chronic hepatitis C patients. Cytokine 1998;10:635-644.
    • (1998) Cytokine , vol.10 , pp. 635-644
    • Martin, J.1    Navas, S.2    Quiroga, J.A.3    Pardo, M.4    Carreno, V.5
  • 21
    • 0036788253 scopus 로고    scopus 로고
    • Peginterferon alone or with ribavirin enhances HCV-specific CD4+ T-helper 1 responses in patients with chronic hepatitis C
    • Kamal SM, Fehr J, Roesler B, Peters T, Rasenack JW: Peginterferon alone or with ribavirin enhances HCV-specific CD4+ T-helper 1 responses in patients with chronic hepatitis C. Gastroenterology 2002;123:1070-1083.
    • (2002) Gastroenterology , vol.123 , pp. 1070-1083
    • Kamal, S.M.1    Fehr, J.2    Roesler, B.3    Peters, T.4    Rasenack, J.W.5
  • 23
    • 0035811016 scopus 로고    scopus 로고
    • RNA virus error catastrophe: Direct molecular test by using ribavirin
    • Crotty S, Cameron CE, Andino R: RNA virus error catastrophe: Direct molecular test by using ribavirin. Proc Natl Acad Sci USA 2001;98:6895-6900.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 6895-6900
    • Crotty, S.1    Cameron, C.E.2    Andino, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.