Enhanced insulin action on glucose transport and insulin signaling in 7-day unweighted rat soleus muscle

Journal of Applied Physiology

Volumn 97, Issue 1, 2004, Pages 63-71

  O'Keefe, Matthew P ^a   Perez, Felipe R ^a   Sloniger, Julie A ^a   Tischler, Marc E ^a   Henriksen, Erik J ^a  

^a UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

Author keywords

Insulin receptor substrate 1; p38 mitogen activated protein kinase; Phosphatidylinositol 3 kinase; Simulated weightlessness; Unweighted soleus

Indexed keywords

GLUCOSE; INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE B; PROTEIN P85; SERINE; WORTMANNIN;

ADAPTATION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME SYNTHESIS; FEMALE; GLUCOSE TRANSPORT; HORMONE ACTION; IMMOBILIZATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; RAT STRAIN; SIGNAL TRANSDUCTION; SIMULATION; SOLEUS MUSCLE; SPACE FLIGHT; WEIGHTLESSNESS;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; BIOLOGICAL TRANSPORT, ACTIVE; BODY WEIGHT; CITRATE (SI)-SYNTHASE; FEMALE; GLUCOSE; GLUCOSE TRANSPORTER TYPE 4; HEXOKINASE; INSULIN; INSULIN RESISTANCE; MONOSACCHARIDE TRANSPORT PROTEINS; MUSCLE PROTEINS; MUSCLE, SKELETAL; ORGAN SIZE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, INSULIN; SIGNAL TRANSDUCTION; TRIGLYCERIDES; WEIGHTLESSNESS SIMULATION;

EID: 3042614035     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/japplphysiol.01361.2003     Document Type: Article

References (39)

1. Adams GR, Ciaos VJ, and Baldwin KM. Skeletal muscle unweighting: spaceflight and ground-based models. J Appl Physiol 95: 2185-2201, 2003.
2. Alford EK, Roy RR, Hodgson JA, and Edgerton VR. Electromyography of rat soleus, medial gastrocnemius, and tibialis anterior during hind limb suspension. Exp Neurol 96: 635-649, 1987.
3. Bonen A, Elder GCB, and Tan MH. Hindlimb suspension increases insulin binding and glucose metabolism. J Appl Physiol 65: 1833-1839, 1988.
4. Childs TE, Spangenburg EE, Vyas DR, and Booth FW. Temporal alterations in protein signaling cascades during recovery from muscle atrophy. Am J Physiol Cell Physiol 285: C391-C398, 2003.
5. Cooney GJ, Thompson AL, Furler SM, Ye J, and Kraegen EW. Muscle long-chain acyl CoA esters and insulin resistance. Ann NY Acad Sci 967: 196-207, 2002.
6. Denton RM and Randle PJ. Concentration of glycerides and phospholipids in rat heart and gastrocnemius muscles: effects of alloxan-diabetes and perfusion. Biochem J 104: 416-422, 1967.
7. Fischbach GD and Robbins N. Changes in contractile properties of disused soleus muscles. J Physiol 201: 305-320, 1969.
8. Folch J, Lees M, and Sloane Stanley JH. A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem 226: 497-509, 1957.
9. Frayn KN and Maycock PF. Skeletal muscle triacylglycerol in the rat: methods for sampling and measurement, and studies of biological variability. J Lipid Res 21: 139-144, 1980.
10. Fujishiro M, Gotoh Y, Katagiri H H, Sakoda H, Ogihara T, Anai M, Onishi Y, Ono H, Abe M, Shojima N, Fukushima Y, Kikuchi M, Oka Y, and Asano T. Three mitogen-activated protein kinases inhibit insulin signaling by different mechanisms in 3T3-L1 adipocytes. Mol Endocrinol 17: 487-497, 2003.
11. Furtado LM, Poon V, and Klip A. GLUT4 activation: some thoughts on possible mechanisms. Acta Physiol Scand 178: 287-296, 2003.
12. Hajduch E, Alessi DR, Hemmings BA, and Hundal HS. Constitutive activation of protein kinase Bα by membrane targeting promotes glucose and system A amino acid transport, protein synthesis, and inactivation of glycogen synthase kinase 3 in L6 muscle cells. Diabetes 47: 1006-1013, 1998.
13. Hansen PA, Gulve EA, and Holloszy JO. Suitability of 2-deoxyglucose for in vitro measurement of glucose transport activity in skeletal muscle. J Appl Physiol 76: 979-985, 1994.
14. Henriksen EJ and Halseth AE. Early alterations in soleus GLUT-4, glucose transport, and glycogen in voluntary running rats. J Appl Physiol 76: 1862-1867, 1994.
15. Henriksen EJ and Jacob S. Effects of captopril on glucose transport activity in skeletal muscle of obese Zucker rats. Metabolism 44: 267-272, 1995.
16. Henriksen EJ, Rodnick KJ, Mondon CE, James DE, and Holloszy JO. Effect of denervation or unweighting on GLUT-4 protein in rat soleus muscle. J Appl Physiol 70: 2322-2327, 1991.
17. Henriksen EJ, Stump CS, Trinh THT, and Beaty SD. Role of glucose transport in glycogen supercompensation in reweighted rat skeletal muscle. J Appl Physiol 80: 1540-1546, 1996.
18. Henriksen EJ, Teachey MK, Taylor ZC, Jacob S, Krämer K, and Hasselwander O. Isomer-specific actions of conjugated linoleic acid on muscle glucose transport in the obese Zucker rat. Am J Physiol Endocrinol Metab 285: E98-E105, 2003.
19. Henriksen EJ and Tischler ME. Glucose uptake in rat soleus: effect of acute unloading and subsequent reloading. J Appl Physiol 64: 1428-1432, 1988.
20. Henriksen EJ and Tischler ME. Time course of the response of carbohydrate metabolism to unloading of the soleus. Metabolism 37: 201-208, 1988.
21. Henriksen EJ, Tischler ME, and Johnson DG. Increased response to insulin of glucose metabolism in the six-day unloaded rat soleus muscle. J Biol Chem 261: 10707-10712, 1986.
22. Ho R, Alcazar O, Fujii N, Hirshman M, and Goodyear LJ. p38γMAPK regulation of glucose uptake in L6 myotubes and mouse skeletal muscle (Abstract). Diabetes 52, Suppl 1: A279, 2003.
23. Jacob S, Machann J, Rett K, Brechtel K, Volk A, Renn W, Maerker E, Matthaei S, Schick F, Claussen CD, and Häring HU. Association of increased intramyocellular lipid content with insulin resistance in lean nondiabetic offspring of type 2 diabetic subjects. Diabetes 48: 1113-1119, 1999.
24. Jaspers SR, Henriksen E, Jacob S, and Tischler ME. Metabolism of branched-chain amino acids in leg muscles from tail-cast suspended intact and adrenalectomized rats. Metabolism 38: 109-114, 1989.
25. Jaspers SR and Tischler ME. Atrophy and growth failure of rat hindlimb muscles in tail-cast suspension. J Appl Physiol 57: 1472-1479, 1984.
26. Kitamura T, Ogawa W, Sakaue H, Hino Y, Kuroda S, Takata M, Matsumoto M, Maeda T, Konishi H, Kikkawa U, and Kasuga M. Requirement for activation of the serine-threonine kinase Akt (protein kinase B) in insulin stimulation of protein synthesis but not of glucose transport. Mol Cell Biol 18: 3708-3717, 1998.
27. Koebel DA, Fell RD, and Steffen JM. Increased glucose and 2-deoxy-d-glucose uptake in skeletal muscle of suspended rats. Aviat Space Environ Med 64: 1016-1022, 1993.
28. Kohn AD, Summers SA, Birnbaum MJ, and Roth RA. Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulated glucose uptake and glucose transporter 4 translocation. J Biol Chem 271: 31372-31378, 1996.
29. Koistinen HA, Chibalin AV, and Zierath JR. Aberrant p38 mitogen-activated protein kinase signaling in skeletal muscle from Type 2 diabetic patients. Diabetologia 46: 1324-1328, 2003.
30. Koyama K, Chen G, Lee Y, and Unger RH. Tissue triglycerides, insulin resistance, and insulin production: implications for hyperinsulinemia of obesity. Am J Physiol Endocrinol Metab 273: E708-E713, 1997.
31. Oakes ND, Cooney GJ, Camilleri S, Chisholm DJ, and Kraegen EW. Mechanisms of liver and muscle insulin resistance induced by chronic high-fat feeding. Diabetes 46: 1768-1774, 1997.
32. O'Keefe MP, Perez FR, Kinnick TR, Tischler ME, and Henriksen EJ. Development of whole-body and skeletal muscle insulin resistance after one day of hindlimb suspension. Metabolism In press.
33. Shepherd PR and Kahn BB. Glucose transporters and insulin action. N Engl J Med 341: 248-257, 1999.
34. Srere PA. Citrate synthase. Methods Enzymol 13: 3-10, 1969.
35. Stump CR, Balon TW, and Tipton CM. Effects of insulin and exercise on rat hindlimb muscles after simulated microgravity. J Appl Physiol 73: 2044-2053, 1992.
36. Thomason DB and Booth FW. Atrophy of the soleus muscle by hindlimb unweighting. J Appl Physiol 68: 1-12, 1990.
37. Ueki K, Yamamoto-Honda R, Kaburagi Y, Yamauchi T, Tobe K, Burgering BMT, Coffer PJ, Komuro I, Akanuma Y, Yazaki Y, and Kadowaki T. Potential role of protein kinase B in insulin-induced glucose transport, glycogen synthesis, and protein synthesis. J Biol Chem 273: 5315-5322, 1998.
38. Uyeda K and Racker E. Regulatory mechanisms in carbohydrate metabolism. VII. Hexokinase and phosphofructokinase. J Biol Chem 240: 4682-4688, 1965.
39. Zierath JR, Krook A, and Wallberg-Henriksson H. Insulin action and insulin resistance in human skeletal muscle. Diabetologia 43: 821-835, 2000.