Characterization of the rates of testosterone metabolism to various products and of glutathione transferase and sulfotransferase activities in rat intestine and comparison to the corresponding hepatic and renal drug-metabolizing enzymes

Chemico-Biological Interactions

Volumn 148, Issue 1-2, 2004, Pages 49-56

  Sohlenius Sternbeck, Anna Karin ^a   Orzechowski, Achim ^a  

^a ASTRAZENECA R AND D   (Sweden)

Author keywords

1 chloro 2,4 dinitrobenzene; CDNB; CYP; cytochrome P450; Cytochrome P450; glutathione transferase; Glutathione transferase; GST; high performance liquid chromatography; HPLC; Intestine; phenol sulfotransferase; pST; Rat; Sulfotransferase; Testosterone

Indexed keywords

16ALPHA HYDROXYTESTOSTERONE; 2ALPHA HYDROXYTESTOSTERONE; 6ALPHA HYDROXYTESTOSTERONE; 6BETA HYDROXYTESTOSTERONE; ANDROSTENEDIONE; DRUG METABOLIZING ENZYME; GLUTATHIONE TRANSFERASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SULFOTRANSFERASE; TESTOSTERONE; TESTOSTERONE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CATALYSIS; CECUM; COLON; COMPARATIVE STUDY; CONTROLLED STUDY; DUODENUM; ENZYME ACTIVITY; HORMONE SYNTHESIS; ILEUM; INTESTINE; INTESTINE MUCOSA; JEJUNUM; KIDNEY; MALE; NONHUMAN; RAT; TESTOSTERONE METABOLISM;

ANIMALS; ARYLSULFOTRANSFERASE; GLUTATHIONE TRANSFERASE; INTESTINAL MUCOSA; INTESTINES; KIDNEY; LIVER; MALE; MICROSOMES, LIVER; RATS; RATS, SPRAGUE-DAWLEY; TESTOSTERONE;

EID: 3042613491     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2004.05.001     Document Type: Article

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