MRI signal hyperintensities in geriatric depression

American Journal of Psychiatry

Volumn 153, Issue 9, 1996, Pages 1212-1215

  Greenwald, Blaine S ^a   Kramer Ginsberg, Elisse ^b   Krishnan, K Ranga Rama ^b   Ashtari, Manzar ^b   Aupperle, Peter M ^b   Patel, Mahendra ^b  

^a ZUCKER HILLSIDE HOSPITAL   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

AGED; ARTICLE; BASAL GANGLION; CEREBROVASCULAR DISEASE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEMOGRAPHY; DEPRESSION; FEMALE; GERONTOPSYCHIATRY; GRAY MATTER; HUMAN; MAJOR CLINICAL STUDY; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; ONSET AGE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RATING SCALE; SINGLE BLIND PROCEDURE;

EID: 0029774110     PISSN: 0002953X     EISSN: None     Source Type: Journal    
DOI: 10.1176/ajp.153.9.1212     Document Type: Article

References (19)

1. Chimowitz MI, A wad IA, Furlan AJ: Periventricular lesions on MRI: facts and theories. Stroke 1989; 20:963-967
2. Krishnan KRR, Goli V, Ellinwood EH, France RD, Blazer DB, Nemcroff CB: Leukoencephalopathy in patients diagnosed as major depressive. Biol Psychiatry 1988; 23:519-522
3. Coffey CE, Figiel GS, Djang WT, Cress M, Saunders WB, Weiner RD: Leukoencephalopathy in elderly depressed patients referred for ECT. Biol Psychiatry 1988; 24:143-161
4. Coffey CE, Figiel GS, Djang WT, Saunders WB, Weiner RD: White matter hyperintensity on magnetic resonance imaging: clinical and neuroanatomical correlates in the depressed elderly. J Neuropsychiatry 1989; 1:135-144
5. Coffey CE, Figiel GS, Djang WT, Weiner RD: Subcortical hyper-intensity on magnetic resonance imaging: a comparison of normal and depressed elderly subjects. Am J Psychiatry 1990; 147: 187-189
6. Figiel GS, Krishnan KRR, Doraiswamy MP, Rao VP, Nemeroff CB, Boyko OB: Subcortical hyperintensities on brain magnetic resonance imaging: a comparison between late age onset and early onset elderly depressed subjects. Neurobiol Aging 1991; 26:245-247
7. Rabins PV, Pearlson GD, Aylward E, Kumar AJ, Dowell K: Cortical magnetic resonance imaging changes in elderly inpatients with major depression. Am J Psychiatry 1991; 148:617-620
8. Fujikawa T, Yamawaki S, Touhouda Y: Incidence of silent cerebral infarction in patients with major depression. Stroke 1993; 24:1631-1634
9. Spitzer RL, Williams JBW, Gibbon M: Structured Clinical Interview for DSM-III-R (SCID). New York, New York State Psychiatric Institute, Biometrics Research, 1988
10. Hamilton M: A rating scale for depression. J Neurol Neurosurg Psychiatry 1960; 23:56-62
11. Guy W (ed): ECDEU Assessment Manual for Psychopharmacology: Publication ADM 76-338. Washington, DC, US Department of Health, Education, and Welfare, 1976, pp 534-537
12. Krishnan KRR, Boyko OB, McDonald WM, Charles HC, MacFall JR, Tupler EA, Upchurch EW: Magnetic-resonance morphometry: image analysis methodology development for affective disorder. Depression 1993; 1:159-171
13. Krishnan KRR: Neuroanatomic substrates of depression in the elderly. J Geriatr Psychiatry Neurol 1993; 1:39-58
14. Stern Y: Behavior and the basal ganglia, in The Dementias. Edited by Mayeux R, Rosen WG. New York, Raven Press, 1983, pp 195-209
15. Zubenko GS, Sullivan P, Nelson JP, Belle SH, Huff FJ, Wolf GL: Brain imaging abnormalities in mental disorders of late life. Arch Neurol 1990; 47:1107-1111
16. Miller DS, Kumar A, Yousem DM, Gottleib GL: MRI high-intensity signals in late-life depression and Alzheimer's disease: a comparison of subjects without major vascular risk factors. Am J Geriatr Psychiatry 1994; 2:332-337
17. Coffey CE, Wilkinson WE, Weiner RD, Parashos IA, Djang WT, Webb CM, Figiel GS, Spritzer CE: Quantitative cerebral anatomy in depression: a controlled magnetic resonance imaging study. Arch Gen Psychiatry 1993; 50:7-16
18. Starkstein SE, Robinson RG, Price TR: Comparison of cortical and subcortical lesions in the production of poststroke mood disorders. Brain 1987; 110:1045-1059
19. Dupont RM, Jernigan TL, Heindel W, Butters N, Shafer K, Wilson T, Hesselink J, Gillin JC: Magnetic resonance imaging and mood disorders: localization of white matter and other subcortical abnormalities. Arch Gen Psychiatry 1995; 52:747-755