Expression of mitochondria-dependent apoptosis genes (p53, Bax, and Bcl-2) in rat granulosa cells during follicular development

Journal of the Society for Gynecologic Investigation

Volumn 11, Issue 5, 2004, Pages 311-317

  Choi, DooSeok ^a   Hwang, SeongSoo ^b   Lee, EunYoung ^b   Yoon, Sarah ^b   Yoon, Byung Koo ^b   Bae, DukSoo ^b  

^a Sungkyunkwan University School of Medicine   (South Korea)

^b NONE

Author keywords

Apoptosis; follicular development; mitochondria dependent genes; rat granulosa cells

Indexed keywords

CASPASE 3; CHORIONIC GONADOTROPIN; ESTROGEN; FOLLITROPIN; MESSENGER RNA; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53;

ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL CULTURE; CELL DEATH; CELL SELECTION; CONTROLLED STUDY; CORRELATION ANALYSIS; CULTURE MEDIUM; DOWN REGULATION; FEMALE; FLUORESCENCE ANALYSIS; GRANULOSA CELL; HORMONE ACTION; MITOCHONDRION; NONHUMAN; OVARY; OVARY FOLLICLE DEVELOPMENT; OVARY FUNCTION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RAT; STATISTICAL SIGNIFICANCE; WESTERN BLOTTING;

ANIMALS; BCL-2-ASSOCIATED X PROTEIN; CHORIONIC GONADOTROPIN; ESTROGENS; FEMALE; FOLLICLE STIMULATING HORMONE; GENES, BCL-2; GENES, P53; GRANULOSA CELLS; MITOCHONDRIA; OVARIAN FOLLICLE; OVARY; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS;

EID: 3042587324     PISSN: 10715576     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jsgi.2004.01.015     Document Type: Article

References (30)

1. Arends M.J., Morris R.G., Wyllie A.H. Apoptosis The role of the endonuclease. Am J Pathol. 136:1990;593-608
2. Hughes F.M. Jr, Gorospe W.C. Biochemical identification of apoptosis (programmed cell death) in granulosa cells Evidence for a potential mechanism underlying follicular atresia. Endocrinology. 129:1991;2415-2422
3. Tilly J.L., Billig H., Kowalski K.I., Hsueh A.J. Epidermal growth factor and basic fibroblast growth factor suppress the spontaneous onset of apoptosis in cultured rat ovarian granulosa cells and follicles by a tyrosine kinase-dependent mechanism. Mol Endocrinol. 6:1992;1942-1950
4. Tilly J.L., Kowalski K.I., Schomberg D.W., Hsueh A.J. Apoptosis in atretic ovarian follicles is associated with selective decreases in messenger ribonucleic acid transcripts for gonadotropin receptors and cytochrome P450 aromatase. Endocrinology. 131:1992;1670-1676
5. Chinnaiyan A.M. The apoptosome Heart and soul of the cell death machine. Neoplasia. 1:1999;5-15
6. Zimmermann K.C., Green D.R. How cells die Apoptosis pathways. J Allergy Clin Immunol. 108:2001;S99-103
7. Kluck R.M., Bossy-Wetzel E., Green R.D., Newmeyer D.D. The release of cytochrome c from mitochondria A primary site for Bcl-2 regulation of apoptosis. Science. 275:1997;1132-1136
8. Yang J., Liu X., Bhalla K., et al. Prevention of apoptosis by Bcl-2 Release of cytochrome c from mitochondria blocked. Science. 275:1997;1129-1132
9. Tilly K.I., Banerjee S., Banerjee P.P., Tilly J.L. Expression of the p53 and Wilms' tumor suppressor genes in the rat ovary Gonadotropin regression in vivo and immunohistochemical localization of nuclear p53 protein to apoptotic granulosa cells of atretic follicles. Endocrinilogy. 136:1995;1394-1402
10. Jurgensmeier J.M., Xie Z., Deveraux Q., Ellerby L., Bredesen D., Reed J.C. Bax directly induces release of cytochrome c from isolated mitochondria. Proc Natl Acad Sci U S A. 95:1998;4997-5002
11. Porter A.G., Janicke R.U. Emerging roles of caspase-3 in apoptosis. Cell Death Differ. 6:1999;99-104
12. Billig H., Furuta I., Hsueh A.J. Estrogens inhibit and androgens enhance ovarian granulosa cell apoptosis. Endocrinology. 133:1993;2204-2212
13. Robker R.L., Richards J.S. Hormone-induced proliferation and differentiation of granulosa cells A coordinated balance of the cell cycle regulators cyclin D2 and p27Kip1. Mol Endocrinol. 12:1998;924-940
14. Ratoosh S.L., Richards J.S. Regulation of the content and phosphorylation of RII by adenosine 3, 5-monophosphate, follicle-stimulating hormone, and estradiol in cultured granulosa cells. Endocrinology. 117:1985;917-927
15. Uberla K., Platzer C., Diamantstein T., Blankenstein T. Generation of competitor DNA fragments for quantitative PCR. PCR Methods Appl. 1:1991;136-139
16. Kaipai A., Hsueh A.J.W. Regulation of ovarian follicular atresia. Annu Rev Physiol. 59:1997;349-363
17. Tilly J.L., Tilly K.I., Kenton M.L., Johnson A.L. Expression of the bcl-2 gene family in the immature rat ovary Equine chorionic gonadotropin-mediated inhibition of apoptosis is associated with decrease bax and constitutive bcl-2 and bcl-xlong messenger ribonucleic acid levels. Endocrinology. 136:1995;232-241
18. Greenwald G.S., Roy S.K. Follicular development and its control. Knobil E., Neill J.D. The physiology of reproduction. 1994;629-660 Raven Press, New York
19. Sadrkhanloo R., Hofeditz C., Erickson G.F. Evidence for widespread atresia in the hypophysectomized estrogen-treated rat. Endocrinlogy. 120:1987;146-155
20. Braw R.H., Tsafriri A. Effect of PMSG on follicular atresia in the rat ovary. J Reprod Fertil. 59:1980;267-272
21. Li J., Kim J.M., Liston P., et al. Expression of inhibitor of apoptosis proteins (IAPs) in rat granulosa cells during ovarian follicular development and atresia. Endocrinology. 139:1998;1321-1328
22. Korsmeyer S.J. Bcl-2 initiates a new category of oncogenes; regulators of cell death. Blood. 80:1992;879-886
23. Reed J.C. Bcl-2 and the regulation of programmed cell death. J Cell Biol. 124:1994;1-6
24. Miyashita T., Krajewski S., Krajewska M., et al. Tumor suppressor p53 is a regulator of Bcl-2 and Bax gene expression in vitro and in vivo. Oncogene. 9:1994;1799-1805
25. Bernardi P., Broekemeier K.M., Pfeiffer D.R. Recent progress on regulation of the mitochondrial permeability transition pore A cyclosporin-sensitive pore in the inner mitochondrial membrane. J Bioenerg Biomembr. 26:1994;509-517
26. Liu X., Kim C.N., Yang J., Jemmerson R., Wang X. Induction of apoptotic program in cell-free extracts Requirement for dATP and cytochrome c. Cell. 86:1996;147-157
27. Hay M.F., Cran D.G., Moor R.M. Structural changes occurring during atresia in ovarian follicles. Cell Tissue Res. 169:1976;515-529
28. Breckwoldt M., Selvaraj N., Aharoni D., et al. Expression of Ad4-BP/cytochrome P450 side chain cleavage enzyme and induction of cell death in long-term cultures of human granulosa cells. Mol Hum Reprod. 2:1996;391-400
29. Makrigiannakis A., Coukos G., Christofidou-Solomidou M., et al. N-cadherin-mediated human granulosa cell adhesion prevents apoptosis A role in follicular atresia and luteolysis? Am J Pathol. 154:1999;1391-1406
30. Schor N.F., Tyurina Y.Y., Tyurin V.A., Kagan V.E. Differential membrane antioxidant effects of immediate and long-term estradiol treatment of MCF-7 breast cancer cells. Biochem Biophys Res Commun. 260:1999;410-415