Prolongation of allograft survival in CCR7-deficient mice

Transplantation

Volumn 77, Issue 12, 2004, Pages 1809-1814

  Beckmann, Jan H ^a   Yan, Sheng ^a,b   Lührs, Heike ^a   Heid, Bettina ^a   Skubich, Susanne ^a   Förster, Reinhold ^a   Hoffmann, Matthias W ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b ZHEJIANG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CCR7; CYCLOSPORIN A;

ALLOGRAFT; ALLOIMMUNITY; ALLOTRANSPLANTATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DENDRITIC CELL; FLOW CYTOMETRY; GRAFT REJECTION; GRAFT SURVIVAL; HEART GRAFT; IMMUNE RESPONSE; IMMUNOHISTOLOGY; LYMPHOCYTE; LYMPHOID ORGAN; MOUSE; NONHUMAN; PRIORITY JOURNAL; SKIN GRAFT; SPLENECTOMY;

ANIMALS; B-LYMPHOCYTES; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; FLOW CYTOMETRY; GRAFT SURVIVAL; HEART TRANSPLANTATION; HOMOZYGOTE; LYMPHOCYTE COUNT; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; RECEPTORS, CHEMOKINE; SKIN TRANSPLANTATION; T-LYMPHOCYTES; TIME FACTORS; TRANSPLANTATION, HOMOLOGOUS;

EID: 3042569764     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.TP.0000131159.25845.EB     Document Type: Article

References (17)

1. Ascher NL, Hoffman RA, Hanto DW, et al. Cellular basis of allograft rejection. Immunol Rev 1984; 77: 217-232.
2. Cyster JG. Chemokines and cell migration in secondary lymphoid organs. Science 1999; 286: 2098-2102.
3. Forster R, Schubel A, Breitfeld D, et al. CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs. Cell 1999; 99: 23-33.
4. Hancock WW, Lu B, Gao W, et al. Requirement of the chemokine receptor CXCR3 for acute allograft rejection. J Exp Med 2000; 192: 1515-1520.
5. Gao W, Topham PS, King JA, et al. Targeting of the chemokine receptor CCR1 suppresses development of acute and chronic cardiac allograft rejection. J Clin Invest 2000; 105: 35-44.
6. Gao W, Faia KL, Csizmadia V, et al. Beneficial effects of targeting CCR5 in allograft recipients. Transplantation 2001; 72: 1199-1205.
7. Robinson LA, Nataraj C, Thomas DW, et al. A role for fractalkine and its receptor (CX3CR1) in cardiac allograft rejection. J Immunol 2000; 165: 6067-6072.
8. Corry RJ, Winn HJ, Russell PS. Heart transplantation in congenic strains of mice. Transplant Proc 1973; 5: 733-735.
9. Billingham RE, Medawar PB. The technique of free skin grafting in mammals. J Exp Biol 1951; 28: 385-401.
10. Larsen CP, Elwood ET, Alexander DZ, et al. Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways. Nature 1996; 381(6581): 434-438.
11. Lakkis FG, Arakelov A, Konieczny BT, et al. Immunologic 'ignorance' of vascularized organ transplants in the absence of secondary lymphoid tissue. Nat Med 2000; 6(6): 686-688.
12. Chin R, Zhou P, Alegre ML, et al. Confounding factors complicate conclusions in aly model. Nat Med 2001; 7(11): 1165-1166.
13. Zhou P, Hwang KW, Palucki D, et al. Secondary lymphoid organs are important but not absolutely required for allograft responses. Am J Transplant 2003; 3: 259-266.
14. Tang ML, Hale LP, Steeber DA, et al. L-selectin is involved in lymphocyte migration to sites of inflammation in the skin: Delayed rejection of allografts in L-selectin-deficient mice. J Immunol 1997; 158: 5191-5199.
15. Kreisel D, Krupnick AS, Gelman AE, et al. Non-hematopoietic allograft cells directly activate CD8+ T cells and trigger acute rejection: An alternative mechanism of allorecognition. Nat Med 2002; 8: 233-239.
16. Kreisel D, Krupnick AS, Balsara KR, et al. Mouse vascular endothelium activates CD8+ T lymphocytes in a B7-dependent fashion. J Immunol 2002; 169: 6154-6161.
17. Larsen CP, Steinman RM, Witmer-Pack M, et al. Migration and maturation of Langerhans cells in skin transplants and explants. J Exp Med 1990; 172: 1483-1493.