Analysis of HLA genes in families with autoimmune diabetes and thyroiditis

Human Immunology

Volumn 65, Issue 6, 2004, Pages 640-647

  Levin, Lara ^a   Ban, Yoshiyuki ^a   Concepcion, Erlinda ^a   Davies, Terry F ^a   Greenberg, David A ^b   Tomer, Yaron ^a,c  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

^c MOUNT SINAI MEDICAL CENTER   (United States)

Author keywords

autoimmune thyroid disease; genetics; HLA; linkage; type 1 diabetes

Indexed keywords

HLA ANTIGEN CLASS 2; HLA DR3 ANTIGEN; HLA DR4 ANTIGEN;

ALLELE; ARTICLE; AUTOIMMUNE DISEASE; CONTROLLED STUDY; FEMALE; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENETIC ANALYSIS; GENETIC SUSCEPTIBILITY; GENOME ANALYSIS; HASHIMOTO DISEASE; HLA SYSTEM; HUMAN; IMMUNOGENETICS; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; MALE; MULTIGENE FAMILY; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; RISK ASSESSMENT; SCORING SYSTEM; STATISTICAL SIGNIFICANCE;

ALLELES; DIABETES MELLITUS, TYPE 1; GENETIC PREDISPOSITION TO DISEASE; HLA-DR3 ANTIGEN; HLA-DR4 ANTIGEN; HUMANS; LINKAGE DISEQUILIBRIUM; QUANTITATIVE TRAIT LOCI; THYROIDITIS, AUTOIMMUNE;

EID: 3042569014     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humimm.2004.02.026     Document Type: Article

References (43)

1. Levin L., Tomer Y. The etiology of autoimmune diabetes and thyroiditis evidence for common genetic susceptibility. Autoimmun Rev. 2:2003;377
2. Weetman A.P., Jenkins R.C. Disease associations with autoimmune thyroid disease. Thyroid. 12:2002;977
3. Kordonouri O., Klinghammer A., Lang E.B., Gruters-Kieslich A., Grabert M., Holl R.W. Thyroid autoimmunity in children and adolescents with type 1 diabetes a multicenter survey. Diabetes Care. 25:2002;1346
4. Bright G.M., Blizzard R.M., Kaiser D.L., Clarke W.L. Organ-specific autoantibodies in children with common endocrine diseases. J Pediatr. 100:1982;8
5. McCanlies E., O'Leary L.A., Foley T.P., Kramer M.K., Burke J.P., Libman A., Swan J.S., Steenkiste A.R., McCarthy B.J., Trucco M., Dorman J.S. Hashimoto's thyroiditis and insulin-dependent diabetes mellitus differences among individuals with and without abnormal thyroid function. J Clin Endocrinol Metab. 83:1998;1548
6. Burek C.L., Rose N.R., Guire K.E., Hoffman W.H. Thyroid autoantibodies in black and in white children and adolescents with type 1 diabetes mellitus and their first degree relatives. Autoimmunity. 7:1990;157
7. Riley W.J., Maclaren N.K., Lezotte D.C., Spillar R.P., Rosenbloom A.L. Thyroid autoimmunity in insulin-dependent diabetes mellitus the case for routine screening. J Pediatr. 99:1981;350
8. Holl R.W., Bohm B., Loos U., Grabert M., Heinze E., Homoki J. Thyroid autoimmunity in children and adolescents with type 1 diabetes mellitus effect of age, gender and HLA type. Horm Res. 52:1999;113
9. Tomer Y, Greenberg DA, Davies TF: The genetic susceptibility to type 1 (insulin dependent) diabetes mellitus and autoimmune thyroid diseases: from epidemiological observations to gene mapping. In Volpe R (ed): Contemporary Endocrinology: Autoimmune Endocrinopathies. Totowa, NJ, Humana Press, 1999
10. Pociot F., McDermott M.F. Genetics of type 1 diabetes mellitus. Genes Immun. 3:2002;235
11. Farid N.R., Bear J.C. The human major histocompatibility complex and endocrine disease. Endocr Rev. 2:1981;50
12. Bode H.H., Dorf M.E., Forbes A.P. Familial lymphocytic thyroiditis analysis of linkage with histocompatibility and blood group. J Clin Endocrinol Metab. 37:1973;692
13. Roman S.H., Greenberg D.A., Rubinstein P., Wallenstein S., Davies T.F. Genetics of autoimmune thyroid disease lack of evidence for linkage to HLA within families. J Clin Endocrinol Metab. 74:1992;496
14. Barbesino G., Tomer Y., Concepcion E.S., Davies T.F., Greenberg D.A. Linkage analysis of candidate genes in autoimmune thyroid disease I. Selected immunoregulatory genes. J Clin Endocrinol Metab. 83:1998;1580
15. Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Diabetes Care. 20:1997;1183
16. Tomer Y., Barbesino G., Greenberg D.A., Concepcion E.S., Davies T.F. Mapping the major susceptibility loci for familial Graves' and Hashimoto's diseases Evidence for genetic heterogeneity and gene interactions. J Clin Endocrinol Metab. 84:1999;4656
17. Tomer Y, Ban Y, Concepcion E, Barbesino G, Villanueva R, Greenberg DA, Davies TF: Common and unique susceptibility loci in Graves' and Hashimoto's diseases: results of whole genome screening in a dataset of 102 multiplex multi-generational families. Am J Hum Genet 73:736, 2003
18. Marsh S.G., Bodmer J.G., Albert E.D., Bodmer W.F., Bontrop R.E., Dupont B., Erlich H.A., Hansen J.A., Mach B., Mayr W.R., Parham P., Petersdorf E.W., Sasazuki T., Schreuder G.M., Strominger J.L., Svejgaard A., Terasaki P.I. Nomenclature for factors of the HLA system, 2000. Hum Immunol. 62:2001;419
19. Westman P., Kuismin T., Partanen J., Koskimies S. An HLA-DR typing protocol using group-specific PCR-amplification followed by restriction enzyme digests. Eur J Immunogenet. 20:1993;103
20. Ott J. A computer program for linkage analysis of general human pedigrees. Am J Hum Genet. 28:1976;528
21. Greenberg D.A., Abreu P., Hodge S.E. The power to detect linkage in complex disease by means of simple LOD-score analyses. Am J Hum Genet. 63:1998;870
22. Kyvik K.O., Green A., Beck-Nielsen H. Concordance rates of insulin dependent diabetes mellitus a population based study of young Danish twins. BMJ. 311:1995;913
23. Brix T.H., Christensen K., Holm N.V., Harvald B., Hegedus L. A population-based study of Graves' diseases in Danish twins. Clin Endocrinol. 48:1998;397
24. Gudbjartsson D.F., Jonasson K., Frigge M.L., Kong A. Allegro, a new computer program for multipoint linkage analysis. Nat Genet. 25:2000;12
25. Dib C., Faure S., Fizames C., Samson D., Drouot N., Vignal A., Millasseau P., Marc S., Hazan J., Seboun E., Lathrop M., Gapay G., Morissete J., Weissenbach J. A comprehensive genetic map of the human genome base on 5, 264 microsatellites. Nature. 380:1996;152
26. Greenberg DA, Abreu PC: Determining trait locus position from multipoint analysis: Accuracy and power of three different statistics. Genet Epidemiol 21:299, 2001
27. Kruglyak L., Daly M.J., Reeve-Daly M.P., Lander E.S. Parametric and nonparametric linkage analysis a unified multipoint approach. Am J Hum Genet. 58:1996;1347
28. Spielman R.S., McGinnis R.E., Ewens W.J. Transmission test for linkage disequilibrium the insulin gene region and insulin-dependent diabetes mellitus. Am J Hum Genet. 52:1993;506
29. Ban Y., Davies T.F., Greenberg D.A., Concepcion E.S., Tomer Y. The influence of human leucocyte antigen (HLA) genes on autoimmune thyroid disease (AITD) results of studies in HLA-DR3 positive AITD families. Clin Endocrinol (Oxf). 57:2002;81
30. Hawkins B.R., Ma J.T., Lam K.S., Wang C.C., Yeung R.T. Analysis of linkage between HLA haplotype and susceptibility to Graves' disease in multiple-case Chinese families in Hong Kong. Acta Endocrinol (Copenh). 110:1985;66
31. Sakai K., Shirasawa S., Ishikawa N., Ito K., Tamai H., Kuma K., Akamizu T., Tanimura M., Furugaki K., Yamamoto K., Sasazuki T. Identification of susceptibility loci for autoimmune thyroid disease to 5q31-q33 and Hashimoto's thyroiditis to 8q23-q24 by multipoint affected sib-pair linkage analysis in Japanese. Hum Mol Genet. 10:2001;1379
32. Vaidya B., Imrie H., Perros P., Young E.T., Kelly W.F., Carr D., Large D.M., Toft A.D., McCarthy M.I., Kendall-Taylor P., Pearce S.H. The cytotoxic T lymphocyte antigen-4 is a major Graves' disease locus. Hum Mol Genet. 8:1999;1195
33. Shields D.C., Ratanachaiyavong S., McGregor A.M., Collins A., Morton N.E. Combined segregation and linkage analysis of Graves' disease with a thyroid autoantibody diathesis. Am J Hum Genet. 55:1994;540
34. Ban Y., Davies T.F., Greenberg D.A., Concepcion E.S., Tomer Y. The influence of human leucocyte antigen (HLA) genes on autoimmune thyroid disease (AITD) results of studies in HLA-DR3 positive AITD families. Clin Endocrinol (Oxf). 57:2002;81
35. Pociot F., McDermott M.F. Genetics of type 1 diabetes mellitus. Genes Immun. 3:2002;235
36. Balducci-Silano P.L., Layrisse Z., Dominguez E., Amaro R., Gunczler P., Lanes R., Zaro R. HLA-DQA1 and DQB1 allele and genotype contribution to IDDM susceptibility in an ethnically mixed population. Eur J Immunogenet. 21:1994;405
37. Fernandes A.P., Louzada-Junior P., Foss M.C., Donadi E.A. HLA-DRB1, DQB1, and DQA1 allele profile in Brazilian patients with type 1 diabetes mellitus. Ann N Y Acad Sci. 958:2002;305
38. Holl R.W., Bohm B., Loos U., Grabert M., Heinze E., Homoki J. Thyroid autoimmunity in children and adolescents with type 1 diabetes mellitus effect of age, gender and HLA type. Horm Res. 52:1999;113
39. Chuang L.M., Wu H.P., Chang C.C., Tsai W.Y., Chang H.M., Tai T.Y., Lin B.J. HLA DRB1/DQA1/DQB1 haplotype determines thyroid autoimmunity in patients with insulin-dependent diabetes mellitus. Clin Endocrinol (Oxf). 45:1996;631
40. Allen D.B., MacDonald M.J., Gottschall J.L., Hunter J.B. Autoimmune thyroid phenomena are not evidence for human lymphocyte antigen-genetic heterogeneity in insulin-dependent diabetes. Am J Med Genet. 33:1989;405
41. Djilali-Saiah I., Bertin E., Larger E., Timsit J., Assan R., Boitard C., Bach J.F., Caillat-Zucman S. Major histocompatibility class II genes polymorphism in insulin dependent diabetes mellitus with or without associated thyroid autoimmunity. Hum Immunol. 59:1998;176
42. Payami H., Joe S., Thomson G. Autoimmune thyroid disease in type 1 diabetes. Genet Epidemiol. 6:1989;137
43. Torfs C.P., King M.-C., Huey B., Malmgren J., Grumet F.C. Genetic interrelationship between insulin-dependent diabetes mellitus, the autoimmune thyroid diseases, and rheumatoid arthritis. Am J Hum Genet. 38:1986;170