Effect of recombinant factor VIIa on melagatran-induced inhibition of thrombin generation and platelet activation in healthy volunteers

Thrombosis and Haemostasis

Volumn 91, Issue 6, 2004, Pages 1090-1096

  Wolzt, Michael ^a   Levi, Marcel ^b   Sarich, Troy C ^c   Boström, Stig L ^d   Erikkson, Ulf G ^d   Erikkson Lepkowska, Maria ^d   Svensson, Mia ^d   Weitz, Jeffrey I ^e   Elg, Margareta ^d   Wåhlander, Karin ^d,f  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

^c ASTRAZENECA   (United Kingdom)

^d ASTRAZENECA R AND D   (Sweden)

^e MCMASTER UNIVERSITY   (Canada)

^f SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Anticoagulant; FVIIa; Melagatran; Shed blood; Ximelagatran

Indexed keywords

ALPHA 2 ANTIPLASMIN; BETA THROMBOGLOBULIN; BLOOD CLOTTING FACTOR 7A; FIBRINOPEPTIDE A; MELAGATRAN; PLACEBO; PROTHROMBIN COMPLEX; RECOMBINANT BLOOD CLOTTING FACTOR 7A; THROMBIN; THROMBIN ACTIVATABLE FIBRINOLYSIS INHIBITOR; THROMBIN ANTITHROMBIN COMPLEX; THROMBIN INHIBITOR; XIMELAGATRAN;

ADULT; ANTICOAGULATION; ARTICLE; BLOOD CLOTTING PARAMETERS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG BLOOD LEVEL; DRUG EFFECT; DRUG INFUSION; DRUG MECHANISM; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; PARALLEL DESIGN; PARTIAL THROMBOPLASTIN TIME; PRIORITY JOURNAL; PROTHROMBIN TIME; QUANTITATIVE ANALYSIS; RANDOMIZED CONTROLLED TRIAL; SINGLE BLIND PROCEDURE; STEADY STATE; THROMBOCYTE ACTIVATION; VENOUS BLOOD; VOLUNTEER;

EID: 3042531845     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/th03-09-0605     Document Type: Article

References (35)

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