MCM2 - A promising marker for premalignant lesions of the lung: A cohort study

BMC Cancer

Volumn 1, Issue , 2001, Pages

  Tan, Dong Feng ^a   Huberman, Joel A ^a   Hyland, Andrew ^a   Loewen, Gregory M ^a   Brooks, John S J ^a   Beck, Amy F ^a   Todorov, Ivan T ^b   Bepler, Gerold ^a  

^a ROSWELL PARK CANCER INSTITUTE   (United States)

^b CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

KI 67 ANTIGEN; MINICHROMOSOME MAINTENANCE PROTEIN 2; MONOCLONAL ANTIBODY KI 67; PROTEIN ANTIBODY; TUMOR MARKER; UNCLASSIFIED DRUG; DIAGNOSTIC AGENT; MCM2 PROTEIN, MAMMALIAN; NUCLEAR PROTEIN;

ARTICLE; BRONCHUS BIOPSY; CANCER SURVIVAL; CARCINOMA IN SITU; CELL ASSAY; CELL PROLIFERATION; CELL SURFACE; COHORT ANALYSIS; CONTROLLED STUDY; EARLY DIAGNOSIS; HUMAN; HUMAN TISSUE; LUNG ALVEOLUS EPITHELIUM; LUNG CANCER; LUNG DYSPLASIA; MAJOR CLINICAL STUDY; METAPLASIA; OBSERVER VARIATION; PRECANCER; SENSITIVITY AND SPECIFICITY; SPUTUM; STAINING; STATISTICAL ANALYSIS; BIOSYNTHESIS; BRONCHUS; CHEMISTRY; CLINICAL TRIAL; DISEASE FREE SURVIVAL; EPITHELIUM CELL; IMMUNOHISTOCHEMISTRY; LUNG TUMOR; MULTICENTER STUDY; PATHOLOGY;

BRONCHI; COHORT STUDIES; DISEASE-FREE SURVIVAL; EPITHELIAL CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; KI-67 ANTIGEN; LUNG NEOPLASMS; NUCLEAR PROTEINS; PRECANCEROUS CONDITIONS; TUMOR MARKERS, BIOLOGICAL;

EID: 3042522612     PISSN: 14712407     EISSN: None     Source Type: Journal    
DOI: 10.1186/1471-2407-1-6     Document Type: Article

References (35)

1. Greenlee RT, Hill-Harmon MB, Murray T, Thun M: Cancer statistics, 2001 CA Cancer J Clin 2001, 51:15-36
2. Mountain C: Revisions in the international system for staging lung cancer Chest 1997, 111:1710-1717
3. Martini N, Ginsberg R: Treatment of stage I and II disease In: Comprehensive textbook of thoracic oncologyEdited by Aisner J, Arriagada R, Green M, Martini N, Perry M. pp. 339-350. Baltimore: Williams and Williams; 1996339-350
4. Patz EF Jr, Rossi S, Harpole DH Jr, Herndon JE, Goodman PC: Correlation of tumor size and survival in patients with stage IA non-small cell lung cancer Chest 2000, 117:1568-1571
5. Patz E, Goodman P, Bepler G: Early detection and screening for lung cancer N Engl J Med 2000, 343:1627-1633
6. Saccomanno G, Archer VE, Auerbach O, Saunders RP, Brennan LM: Development of carcinoma of the lung as reflected in exfoliated cells Cancer 1974, 33:256-270
7. Morice R, Lee J, Kurie J, Khuri F, Ro J, Kemp B, Broxson A, Liu D, Hong W: Bronchial squamous metaplasia and dysplasia in current and former smokers Proc Am Soc Clin Oncol 1999, 18:472a
8. Venmans B, van Boxem T, Smit E, Psotmus P, Sutedja T: Outcome of bronchial carcinoma in situ Chest 2000, 117:1572-1576
9. Tockman MS, Gupta PK, Myers JD, Frost JK, Baylin SB, Gold EB, Chase AM, Wilkinson PH, Mulshine JL: Sensitive and specific monoclonal antibody recognition of human lung cancer antigen on preserved sputum cells: a new approach to early lung cancer detection J Clin Oncol 1988, 6:1685-1693
10. Bechtel JJ, Petty TL, Saccomanno G: Five year survival and later outcome of patients with X-ray occult lung cancer detected by sputum cytology Lung Cancer 2000, 30:1-7
11. Kelman Z, Hurwitz J: Protein-PCNA interactions: a DNA-scanning mechanism? Trends Biochem. Sci. 1998, 23:
12. Tsurimoto T: PCNA, a multifunctional ring on DNA Biochim. Biophys. Acta 1998, 1443:23-39
13. Kreitz S, Fackelmayer FO, Gerdes J, Knippers R: The proliferation-specific human Ki-67 protein is a constituent of compact chromatin Exp. Cell Res. 2000, 261:284-292
14. Endl E, Gerdes J: The Ki-67 protein: fascinating forms and an unknown function Exp Cell Res 2000, 257:231-237
15. Schulter C, Duchrow M, Wohlenberg C, Becker MH, Key G, Flad HD, Gerdes J: The cell proliferation-associated antigen of antibody Ki-67: a very large, ubiquitous nuclear protein with numerous repeated elements, representing a new kind of cell cycle-maintaining proteins J Cell Biol 1993, 123:513-522
16. Maeshima Y, Kashihara N, Sugiyama H, Makino H, Ota Z: Antisense oligonucleotides to proliferating cell nuclear antigen and Ki-67 inhibit human mesangial cell proliferation J Am Soc Nephrol 1996, 7:2219-2229
17. Lavezzi AM, Santambrogio L, Bellaviti N, Biondo B, Nosotti M, Radice F, Matturri L: Prognostic significance of different biomarkers in non-small cell lung cancer Oncol Rep 1999, 6:819-825
18. Fukuse T, Hirata T, Naiki H, Hitomi S, Wada H: Expression of proliferating cell nuclear antigen and CD44 variant isoforms in the primary and metastatic sites of non-small cell lung carcinoma with intrapulmonary metastases Cancer 1999, 86:1174-1181
19. Oyama T, Osaki T, Nose N, Ichiki Y, Inoue M, Imoto H, Yoshimatsu T, Kodate M, Uramoto H, Mizoue T, Yano K, Yasumoto K: Evaluations of p53 immunoreactivity, nucleolar organizer regions, and proliferating cell nuclear antigen in non-small cell lung carcinoma Anticancer Res 2000, 20:505-510
20. Shiba M, Kohno H, Kakizawa K, Iizasa T, Otsuji M, Saitoh Y, Hiroshima K, Ohwada H, Fujisawa T: Ki-67 immunostaining and other prognostic factors including tobacco smoking in patients with resected non-small cell lung carcinoma Cancer 2000, 89:1457-1465
21. Pendleton N, Dixon GR, Burnett HE, Occleston NL, Myskow MW, Green JA: Expression of proliferating cell nuclear antigen (PCNA) in dysplasia of the bronchial epithelium J Pathol 1993, 170:169-172
22. Tormanen U, Nuorva K, Soini Y, Paakko P: Apoptotic activity is increased in parallel with the metaplasia-dysplasia-carcinoma sequence of the bronchial epithelium Br J Cancer 1999, 79:996-1002
23. Kitaguchi S, Takeshima Y, Nishisaka T, Inai K: Proliferative activity, p53 expression and loss of heterozygosity on 3p, 9p and 17p in atypical adenomatous hyperplasia of the lung Hiroshima J Med Sci 1998, 47:17-25
24. Yokose T, Ito Y, Ochiai A: High prevalence of atypical adenomatous hyperplasia of the lung in autopsy specimens from elderly patients with malignant neoplasms Lung Cancer 2000, 29:125-130
25. Todorov IT, Werness BA, Wang HQ, Buddharaju LN, Todorova PD, Slocum HK, Brooks JS, Huberman JA: HsMCM2/BM28: a novel proliferation marker for human tumors and normal tissues Lab Invest 1998, 78:73-78
26. Kearsey SE, Maiorano D, Holmes EC, Todorov IT: The role of MCM proteins in the cell cycle control of genome duplication Bioessays 1996, 18:183-190
27. Lei M, Tye BK: Initiating DNA synthesis: from recruiting to activating the MCM complex J Cell Sci 2001, 14:1447-1454
28. Labib K, Tercero JA, Diffley JFX: Uninterrupted MCM2-7 function required for DNA replication fork progression Science 2000, 288:1643-1647
29. Freeman A, Morris LS, Mills AD, Stoeber K, Laskey RA, Williams GH, Coleman N: Minichromosome maintenance proteins as biological markers of dysplasia and malignancy Clin Cancer Res 1999, 5:2121-2132
30. Williams GH, Romanowski P, Morris L, Madine M, Mills AD, Stoeber K, Marr J, Laskey RA, Coleman N: Improved cervical smear assessment using antibodies against proteins that regulate DNA replication Proc Natl Acad Sci U S A 1998, 95:14932-14937
31. Matthews MJ, Mackay B, Lukeman J: The pathology of non-small cell carcinoma of the lung Semin Oncol 1983, 10:34-55
32. Melamed MR, Flehinger BJ, Zaman MB, Heelan RT, Perchick WA, Martini N: Screening for early lung cancer. Results of the Memorial Sloan-Kettering study in New York Chest 1984, 86:44-53
33. Fontana RS, Sanderson DR, Woolner LB, Taylor WF, Miller WE, Muhm JR: Lung cancer screening: the Mayo program J Occup Med 1986, 28:746-750
34. Tockman MS: Survival and mortality from lung cancer in a screened population. The Johns Hopkins Study Chest 1986, 89 (Suppl):324S-325S
35. Todorov IT, Attaran A, Kearsey SE: BM28, a human member of the MCM2-3-5 family, is displaced from chromatin during DNA replication J. Cell Biol. 1995, 129:1433-1445