Exclusion of PINK1 as candidate gene for the late-onset form of Parkinson's disease in two European populations

Journal of Negative Results in BioMedicine

Volumn 4, Issue , 2005, Pages

  Schlitter, Anna Melissa ^a   Kurz, Martin ^b,c   Larsen, Jan P ^c   Woitalla, Dirk ^d   Mueller, Thomas ^d   Epplen, Joerg T ^a   Dekomien, Gabriele ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

^b HEINRICH HEINE UNIVERSITY   (Germany)

^c STAVANGER UNIVERSITY HOSPITAL   (Norway)

^d ST JOSEF HOSPITAL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE; GLUTAMINE; PTEN INDUCED PUTATIVE KINASE; PTEN-INDUCED PUTATIVE KINASE;

ADULT; AGED; ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; DENATURING HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; EUROPE; EXON; FAMILY HISTORY; GENE; GENE SEQUENCE; GENETIC CODE; GENETIC VARIABILITY; GENOTYPE; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MUTATION; PARKINSON DISEASE; PATHOGENESIS; PINK1 GENE; POPULATION; RISK; SCREENING; SINGLE NUCLEOTIDE POLYMORPHISM; SINGLE STRAND CONFORMATION POLYMORPHISM; ALLELE; GENETICS; GERMANY; MIDDLE AGED; NORWAY; ONSET AGE;

ADULT; AGE OF ONSET; AGED; ALLELES; COHORT STUDIES; GENOTYPE; GERMANY; GLUTAMINE; HUMANS; MIDDLE AGED; MUTATION; NORWAY; PARKINSON DISEASE; PROTEIN KINASES;

EID: 30344483246     PISSN: 14775751     EISSN: 14775751     Source Type: Journal    
DOI: 10.1186/1477-5751-4-10     Document Type: Article

References (19)

1. Gilks WP, Abou-Sleiman PM, Gandhi S, Jain S, Singleton A, Lees AJ, Shaw K, Bhatia KP, Bonifati V, Quinn NP, Lynch J, Healy DG, Holton JL, Revesz T, Wood NW: A common LRRK2 mutation in idiopathic Parkinson's disease. Lancet 2005, 365:415-416.
2. Di Fonzo A, Rohe CF, Ferreira J, Chien HF, Vacca L, Stocchi F, Guedes L, Fabrizio E, Manfredi M, Vanacore N, Goldwurm S, Breedveld G, Sampaio C, Meco G, Barbosa E, Oostra BA, Bonifati V: A frequent LRRK2 gene mutation associated with autosomal dominant Parkinson's disease. Lancet 2005, 365:412-415.
3. Valente EM, Abou-Sleiman PM, Caputo V, Muqit MM, Harvey K, Gispert S, Ali Z, Del Turco D, Bentivoglio AR, Healy DG, Albanese A, Nussbaum R, Gonzalez-Maldonado R, Deller T, Salvi S, Cortelli P, Gilks WP, Latchman DS, Harvey RJ, Dallapiccola B, Auburger G, Wood NW: Hereditary early-onset Parkinson's disease caused by mutations in PINK1. Science 2004, 304:1158-1160.
4. Rogaeva E, Johnson J, Lang AE, Gulick C, Gwinn-Hardy K, Kawarai T, Sato C, Morgan A, Werner J, Nussbaum R, Petit A, Okun MS, McInerney A, Mandel R, Groen JL, Fernandez HH, Postuma R, Foote KD, Salehi-Rad S, Liang Y, Reimsnider S, Tandon A, Hardy J, St George-Hyslop P, Singleton AB: Analysis of the PINK1 gene in a large cohort of cases with Parkinson disease. Arch Neurol 2004, 61:1898-1904.
5. Shen J, Cookson MR: Mitochondria and dopamine: new insights into recessive parkinsonism. Neuron 2004, 43:301-304.
6. Strauss KM, Martins LM, Plun-Favreau H, Marx FP, Kautzmann S, Berg D, Gasser T, Wszolek Z, Muller T, Bornemann A, Wolburg H, Downward J, Riess O, Schulz JB, Kruger R: Loss of function mutations in the gene encoding Omi/HtrA2 in Parkinson's disease. Hum Mol Genet 2005.
7. Beal MF: Mitochondria, oxidative damage, and inflammation in Parkinson's disease. Ann N Y Acad Sci 2003, 991:120-131.
8. Dauer W, Przedborski S: Parkinson's disease: mechanisms and models. Neuron 2003, 39:889-909.
9. Foroud T, Uniacke SK, Liu L, Pankratz N, Rudolph A, Halter C, Shults C, Marder K, Conneally PM, Nichols WC, Parkinson Study G: Heterozygosity for a mutation in the parkin gene leads to later onset Parkinson disease. Neurology 2003, 60:796-801.
10. Oliveira SA, Scott WK, Martin ER, Nance MA, Watts RL, Hubble JP, Koller WC, Pahwa R, Stern MB, Hiner BC, Ondo WG, Allen FHJ, Scott BL, Goetz CG, Small GW, Mastaglia F, Stajich JM, Zhang F, Booze MW, Winn MP, Middleton LT, Haines JL, Pericak-Vance MA, Vance JM: Parkin mutations and susceptibility alleles in lateonset Parkinson's disease.[see comment]. Annals of Neurology 2003, 53:624-629.
11. Borg A DAHKMLHEMP: BRCA1 1675delA and 1135insA account for one third of Norwegian familial breast-ovarian cancer and are associated with later disease onset than less frequent mutations. Dis Markers 1999, Oct;15(1-3):79-84.:.
12. Klein C, Djarmati A, Hedrich K, Schafer N, Scaglione C, Marchese R, Kock N, Schule B, Hiller A, Lohnau T, Winkler S, Wiegers K, Hering R, Bauer P, Riess O, Abbruzzese G, Martinelli P, Pramstaller PP: PINK1, Parkin, and DJ-1 mutations in Italian patients with early-onset parkinsonism. Eur J Hum Genet 2005.
13. Groen JL, Kawarai T, Toulina A, Rivoiro C, Salehi-Rad S, Sato C, Morgan A, Liang Y, Postuma RB, St George-Hyslop P, Lang AE, Rogaeva E: Genetic association study of PINK1 coding polymorphisms in Parkinson's disease. Neurosci Lett 2004, 372:226-229.
14. Healy DG, Abou-Sleiman PM, Ahmadi KR, Muqit MM, Bhatia KP, Quinn NP, Lees AJ, Latchmann DS, Goldstein DB, Wood NW: The gene responsible for PARK6 Parkinson's disease, PINK1, does not influence common forms of parkinsonism. Ann Neurol 2004, 56:329-335.
15. Kurz M, Alves G, Aarsland D, Larsen JP: Familial Parkinson's disease: a community-based study. European Journal of Neurology 2003, 10:159-163.
16. Tandberg E, Larsen JP, Nessler EG, Riise T, Aarli JA: The epidemiology of Parkinson's disease in the county of Rogaland, Norway. Movement Disorders 1995, 10:541-549.
17. Larsen JP, Dupont E, Tandberg E: Clinical diagnosis of Parkinson's disease. Proposal of diagnostic subgroups classified at different levels of confidence. Acta Neurologica Scandinavica 1994, 89:242-251.
18. Hughes AJ, Daniel SE, Kilford L, Lees AJ: Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases. J Neurol Neurosurg Psychiatry 1992, 55:181-184.
19. Jaeckel S, Epplen JT, Kauth M, Miterski B, Tschentscher F, Epplen C: Polymerase chain reaction-single strand conformation polymorphism or how to detect reliably and efficiently each sequence variation in many samples and many genes. Electrophoresis 1998, 19:3055-3061.