Expression of the proto-oncoprotein breast cancer nuclear receptor auxiliary factor (Brx) is altered in eutopic endometrium of women with endometriosis

Fertility and Sterility

Volumn 85, Issue 1, 2006, Pages 63-70

  Hearns Stokes, Rhonda ^a,b,c,d   Mayers, Chantal ^a,c   Zahn, Christopher ^c   Cruess, David ^e   Gustafsson, Jan Åke ^f   Segars, James ^a,b,c   Nieman, Lynnette ^a,g  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^b Combined Federal Fellowship in Reproductive Endocrinology ^*  (United States)

^c UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

^d GENETICS AND IVF INSTITUTE   (United States)

^e Uniformed Services University of the Health Sciences   (United States)

^f KAROLINSKA INSTITUTE   (Sweden)

^g NONE   (United States)

Author keywords

Brx; Endometriosis; Endometrium; Estrogen receptor alpha; Estrogen receptor beta; Immunohistochemistry; Menstrual cycle

Indexed keywords

CELL NUCLEUS RECEPTOR; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; ONCOPROTEIN;

ADULT; ARTICLE; BREAST CANCER; CONTROLLED STUDY; ENDOMETRIOSIS; ENDOMETRIUM; ENDOMETRIUM BIOPSY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MENSTRUAL CYCLE; OBSERVATIONAL STUDY; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN EXPRESSION; PROTEIN LOCALIZATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADULT; BIOPSY; ENDOMETRIOSIS; ENDOMETRIUM; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MENSTRUAL CYCLE; PROTO-ONCOGENE PROTEINS; STROMAL CELLS;

EID: 30344468154     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2005.06.053     Document Type: Article

References (39)

1. K. Barnhart, R. Dunsmoor-Su, C. Coutifaris Effect of endometriosis on in vitro fertilization Fertil Steril 77 2002 1148 1155
2. C.A. Winkel Evaluation and management of women with endometriosis Obstet Gynecol 102 2003 397 408
3. J. Sampson Peritoneal endometriosis due to menstrual dissemination of endometrial tissue into the peritoneal cavity Am J Obstet Gynecol 14 1927 422 469
4. J. Halme, M.G. Hammond, J. Hulka Retrograde menstruation in healthy women and in patients with endometriosis Obstet Gynecol 64 1984 151 154
5. R.F. Kruitwagen, L.G. Poels, W.N. Willemsen, P.H. Jays, C.M. Thomas, R. Rolland Retrograde seeding of endometrial epithelial cells by uterine-tubal flushing Fertil Steril 56 1991 414 420
6. J. Kitawaki, N. Kado, H. Ishihara, H. Koshiba, Y. Kitaoka, H. Honjo Endometriosis the pathophysiology as an estrogen-dependent disease J Steroid Biochem Mol Biol 83 2002 149 155
7. B. Gurates, S. Bulun Endometriosis the ultimate hormonal disease Semin Reprod Med 21 2003 125 134
8. Z. Weihua, S. Saji, S. Makinen, G. Cheng, M. Warner, J.-A. Gustafsson Estrogen receptor (ER) beta, a modulator of ER alpha in the uterus Proc Natl Acad Sci U S A 97 2000 5936 5941
9. H.O. Critchley, T.A. Henderson, R.W. Kelly, G.S. Scobie, L.R. Evans, N.P. Groome Wild-type estrogen receptor (ER beta1) and the splice variant (ERbetacx/beta2) are both expressed within the human endometrium throughout the normal menstrual cycle Clin Endocrinol Metab 87 2002 5265 5273
10. A.W. Brandenberger, D.I. Lebovic, M.K. Tee, I.P. Ryan, J.F. Tseng, R.B. Jaffe Oestrogen receptor (ER)-alpha and (ER)-beta isoforms in normal endometrium and endometriosis-derived stromal cells Mol Hum Reprod 5 1999 651 655
11. A. Witek, U. Mazurek, M. Paul, G. Bierzynska-Macyszyn, T. Wilczok Quantitative analysis of estrogen receptor mRNA in human endometrium throughout the menstrual cycle using real-time reverse transcription-polymerase chain reaction assay Folia Histochem Cytobiol 39 2001 116 118
12. G. Lecce, G. Meduri, M. Ancelin, C. Bergeron, M. Perrot-Applanat Presence of estrogen receptor b in the human endometrium throughout the cycle expression in glandular, stromal, and vascular cells J Clin Endocrinol Metab 86 2001 1379 1386
13. S. Matsuzaki, T. Fukaya, T. Suzuki, T. Murakami, H. Sasano, A. Yajima Oestrogen receptor a and b mRNA expression in human endometrium throughout the menstrual cycle Mol Human Reprod 5 1999 559 564
14. H.O. Critchley, R.M. Brenner, T.A. Henderson, K. Williams, N.R. Nayak, O.D. Slayden Estrogen receptor b, but not estrogen receptor a, is present in the vascular endothelium of the human and nonhuman primate endometrium J Clin Endocrinol Metab 86 2001 1370 1378
15. A.H. Taylor, F. Al-Azzawui Immunolocalisation of oestrogen receptor beta in human tissues J Mol Endocrinol 24 2000 145 155
16. S. Kato, H. Endoh, Y. Masuhiro, T. Kitamoto, S. Uchiyama, H. Sasaki Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase Science 270 1995 1491 1494
17. P.H. Driggers, J.H. Segars, D.M. Rubino The proto-oncoprotein Brx activates estrogen receptor beta by a p38 mitogen-activated protein kinase pathway J Biol Chem 276 2001 46792 46797
18. J.H. Segars, P.H. Driggers Estrogen action and cytoplasmic signaling cascades. Part I membrane-associated signaling complexes Trends Endocrinol Metab 13 2002 349 354
19. D. Rubino, P. Driggers, D. Arbit, L. Kemp, B. Miller, O. Coso Characterization of Brx, a novel Dbl family member that modulates estrogen receptor action Oncogene 16 1998 2513 2526
20. P.H. Driggers, J.H. Segars Estrogen action and cytoplasmic signaling pathways. Part II: the role of growth factors and phosphorylation in estrogen signaling Trends Endocrinol Metab 13 2002 422 428
21. D. Diviani, J. Soderling, J.D. Scott AKAP-Lbc anchors protein kinase A and nucleates Galpha12-selective Rho-mediated stress fiber formation J Biol Chem 276 2001 44247 44257
22. B.T. Miller, D.M. Rubino, P.H. Driggers, B. Haddad, M. Cisar, K. Gray Expression of brx proto-oncogene in normal ovary and in epithelial neoplasms Am J Obstet Gynecol 182 2000 286 295
23. R.A. Cerione, Y. Zheng The Dbl family of oncogenes Curr Opin Cell Biol 8 1996 216 222
24. K. Elkind-Hirsch, J.W. Goldzieher, W.E. Gibbons, P.K. Besch Evaluation of the OvuSTICK urinary luteinizing hormone kit in normal and stimulated menstrual cycles Obstet Gynecol 67 1986 450 453
25. R.W. Noyes, A.T. Hertig, J. Rock Dating the endometrial biopsy Fertil Steril 1 1950 3 25
26. A.M.M. Van Pelt, D.G. De Rooij, B. Van Der Burg, P.T. Van Der Saag, J.-A. Gustafsson, G.G. Kuiper Ontogeny of estrogen receptor-beta expression in rat testis Endocrinology 140 1999 478 483
27. B. Lessey, D. Metzger, A. Haney, K. McCarty Immunohistochemical analysis of estrogen and progesterone receptors in endometriosis comparison with normal endometrium during the menstrual cycle and the effect of medical therapy Fertil Steril 15 1989 409 415
28. H. Wang, H.O. Critchley, R.W. Kelly, D. Shen, D.T. Baird Progesterone receptor subtype B is differentially regulated in human endometrial stroma Mol Hum Reprod 4 1998 407 412
29. R.L. Jones, R.W. Kelly, H.O. Critchley Chemokine and cyclooxygenase-2 expression in human endometrium coincides with leukocyte accumulation Hum Reprod 12 1997 1300 1306
30. S. Daya Understanding statistics chi-square test for larger (r×c) contingency tables Evid Based Obstet Gynecol 3 2001 116 117
31. J.-A. Gustafsson Estrogen receptor beta- a new dimension in estrogen mechanism of action J Endocrinol 163 1999 379 383
32. S. Matsuzaki, T. Murakami, S. Uehara, M. Canis, H. Sasano, K. Okamura Expression of estrogen receptor alpha and beta in peritoneal and ovarian endometriosis Fertil Steril 75 2001 1198 1205
33. Y.Y. Hsieh, C.C. Chang, F.J. Tsai, C.C. Lin, C.H. Tsai Estrogen receptor alpha dinucleotide repeat and cytochrome P450c17alpha gene polymorphisms are associated with susceptibility to endometriosis Fertil Steril 83 2005 567 572
34. H.A. Harris, K.L. Bruner-Tran, X. Zhang, K.G. Osteen, C.R. Lyttle A selective estrogen receptor-{beta} agonist causes lesion regression in an experimentally induced model of endometriosis Hum Reprod 20 2005 936 941
35. R.V. Schillace, J.D. Scott Organization of kinases, phosphatases, and receptor signaling complexes J Clin Invest 103 1999 761 765
36. E. Klussmann, B. Edemir, B. Pepperle, G. Tamma, V. Henn, E. Klauschenz Ht31 the first protein kinase A anchoring protein to integrate protein kinase A and Rho signaling FEBS Lett 507 2001 264 268
37. K.L. VanGolen Relationship between growth factor signaling and motility in aggressive cancers Breast Cancer Res 5 2003 174 179
38. L.C. Giudice, L.C. Kao Endometriosis Lancet 364 2004 1789 1799
39. K.L. Sharpe-Timms Endometrial anomalies in women with endometriosis Ann N Y Acad Sci 943 2001 131 147